Dark soliton in a disorder potential

We consider dark soliton in a Bose-Einstein condensate in the presence of a weak disorder potential. Deformation of the soliton shape is analyzed within the Bogoliubov approach and by employing expansion in eigenstates of the P\"oschl-Teller Hamiltonian. Comparison of the results with the numerical simulations indicates that the linear response analysis reveals good agreement even if the strength of the disorder is of the order of the chemical potential of the system. In the second part of the paper we concentrate on quantum nature of the dark soliton and demonstrate that the soliton may reveal Anderson localization in the presence of a disorder. The Anderson localized soliton may decay due to quasi-particle excitations induced by the disorder. However, we show that the corresponding lifetime is much longer than condensate lifetime in a typical experiment.Comment: 10 pages, 3 figures, version accepted for publication in Phys. Rev.

Coupled variability in primary sensory areas and the hippocampus during spontaneous activity

The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.project NORTE-01-0145-FEDER-000013, supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER). NAPV was supported by Centro Universitario do Rio Grande do Norte, Champalimaud Foundation, and Brazilian National Council for Scientific and Technological Development (CNPq, Grant 249991/2013-6), CC-S (SFRH/BD/51992/2012). AJR (IF/00883/2013). SR by UFRN, CNPq (Research Productivity Grant 308775/2015-5), and S. Paulo Research Foundation FAPESP - Center for Neuromathematics (Grant 2013/07699-0)info:eu-repo/semantics/publishedVersio

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 - Meeting Abstracts - Antwerp, Belgium. 15–20 July 2017

This work was produced as part of the activities of FAPESP Research,\ud Disseminations and Innovation Center for Neuromathematics (grant\ud 2013/07699-0, S. Paulo Research Foundation). NLK is supported by a\ud FAPESP postdoctoral fellowship (grant 2016/03855-5). ACR is partially\ud supported by a CNPq fellowship (grant 306251/2014-0)

Achieving maturity: the state of practice in ontology engineering in 2009

In this paper we give an account of the current state of practice in ontology engineering based on the findings of a six months empirical survey we performed between October 2008 and March 2009 that analysed 148 ontology engineering projects from industry and academia. The survey focused on process-related issues and looked into the impact of research achievements on real-world ontology engineering projects, the complexity of particular ontology development tasks, the level of tool support, and the usage scenarios for ontologies. The main contributions of this survey compared to other works in the ontology engineering community are twofold: Firstly, the size of the data set the results are grounded on is by far larger than every other similar endeavour published in the last years. Secondly, the findings of the survey confirm the fact that ontology engineering is an established engineering discipline in respect of the maturity and level of acceptance of its main components, methodologies, methods and software tools, whereas further research should target the customization of existing technology to the specifics of vertical domains, as well as economic aspects of ontology engineering

Achieving maturity: the state of practice in ontology engineering in 2009

In this paper we give an account of the current state of practice in ontology engineering (OE) based on the findings of a 6 months empirical survey that analyzed 148 OE projects. The survey focused on process-related issues and looked into the impact of research achievements on real-world OE projects, the complexity of particular ontology development tasks, the level of tool support, and the usage scenarios for ontologies. The main contributions of this survey are twofold: 1) the size of the data set is larger than every other similar endeavor; 2) the findings of the survey confirm that OE is an established engineering discipline w.r.t the maturity and level of acceptance of its main components, methodologies, etc. whereas further research should target economic aspects of OE and the customization of existing technology to the specifics of vertical domains

Genetic factors in pathogenesis of diabetes mellitus after kidney transplantation

Maciej Tarnowski,1 Sylwia Słuczanowska-Głabowska,1 Andrzej Pawlik,1 Małgorzata Mazurek-Mochol,2 Elżbieta Dembowska2 1Department of Physiology, 2Department of Periodontology, Pomeranian Medical University, Szczecin, Poland Abstract: Posttransplant diabetes mellitus (PTDM) is one of the major metabolic complications after transplantation of solid organs including the kidney. This type of diabetes mellitus affects allograft survival, cardiovascular complications and overall patient survival. The modifiable risk factors that contribute to PTDM include obesity, some viral infections (eg, hepatitis C virus, cytomegalovirus) and especially immunosuppressive drugs including corticosteroids, tacrolimus, cyclosporine and sirolimus. Currently, predisposing genetic factors have been considered important in PTDM development. The commonly evaluated genetic determinants include genes encoding transcription factors, cytokines, chemokines, adipokines, ionic channels, glucose transporters, cytochrome P450 enzymes and other enzymes metabolizing drugs, drug transporters. Unfortunately, the results of studies are inconclusive and differ between populations. There is a need for large genome-wide association study to identify the genetic risk factors associated with PTDM development. Keywords: diabetes mellitus, kidney, transplantation, gene polymorphism, SN

Wpływ kolejnej laktacji na profil kwasów tłuszczowych w mleku krów wysokowydajnych

The objective of this study was to determine the effect of parity on the fatty acid profile of milk from 42 high-yielding cows, including 15 primiparous cows, 15 cows in their second lactation and 12 cows in their third lactation. Milk yield was evaluated and milk samples (462 in total) were collected between lactation days 6 and 60, at five-day intervals. The concentrations of 43 fatty acids were determined by gas chromatography in extracted fat. Cows in their third lactation were characterized by the highest milk yield – over 305-day lactation, they produced 13,160 kg of milk on average. Milk from primiparous cows had the most desirable fatty acid profile. It contained more (by ca. 12–17%) n-3 fatty acids and less (by 2.89–5.46%) fatty acids that adversely affect human health, compared with the other groups. Among essential fatty acids, differences were noted with respect to CLA (+9.5–9.8%), LNA (+12.7–18.7%) and DHA (+21–23%) to the advantage of the milk fat of primiparous cows.Celem podjętych badań było określenie wpływu kolejnej laktacji na profil kwasów tłuszczowych tłuszczu mleka 42 wysokowydajnych krów: 15 pierwiastek, 15 w drugiej laktacji i 12 w trzeciej laktacji. Oceniano ich wydajność mleczną i od 6. do 60. dnia laktacji co pięć dni pobierano próbki mleka (łącznie 462), a następnie ekstrahowano tłuszcz i metodą chromatografii gazowej określano profil 43 kwasów tłuszczowych. Krowy po trzecim wycieleniu charakteryzowały się najwyższą wydajnością i wyprodukowały w laktacji 305-dniowej średnio 13 160 kg mleka. Pierwiastki produkowały natomiast mleko o najkorzystniejszym profilu kwasów tłuszczowych. Zawierało ono więcej o 12–17% kwasów z grupy n-3 oraz o 2,89–5,46% mniej kwasów o negatywnym oddziaływaniu na zdrowie człowieka. Spośród funkcjonalnych kwasów tłuszczowych różnice na korzyść tłuszczu mleka pierwiastek dotyczyły głównie CLA (+9,5–9,8%), LNA (+12,7–18,7%) i DHA (+21–23%)