The Correlation Between Reading Comprehension and Writing Ability of the Second Year Students of Sman 1 Muaro Sentajo Teluk Kuantan in Recount Texts

The objective of this research is to find out the level of students\u27 ability in reading comprehension and writing ability in recount texts and the correlation between those variables of the second year students of SMAN 1 Muaro Sentajo. The sample of this research was class XI IPS 2 which consist 25 students. The data were collected by using two kinds of test, reading comprehension and written test. The result of this research showed that the students got good level with the average score 73.28 in reading comprehension, and in writing the students got good level with the average score 76.12. The result of this research proved that there is a positive correlation between reading comprehension and writing ability on recount texts. The rxy distribution of coefficient correlation is 0.8. It means that the correlation was in a high level. So, Ha (alternative hypothesis) of this research is accepted, and null hypothesis (Ho) is rejected. Is there any difference between students\u27 reading and writing score? So, the researcher try to find out students\u27 reading and writing score and their correlation. Finally, the researcher suggests for the teacher, they should have some efforts to develop the students\u27 motivation and encourage them to practice their reading comprehension and writing ability in recount texts

Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease

It is widely thought that demyelination contributes to the degeneration of axons and, in combination with acute inflammatory injury, is responsible for progressive axonal loss and persistent clinical disability in inflammatory demyelinating disease. In this study we sought to characterize the relationship between demyelination, inflammation and axonal transport changes using a Plp1-transgenic mouse model of Pelizaeus-Merzbacher disease. In the optic pathway of this non-immune mediated model of demyelination, myelin loss progresses from the optic nerve head towards the brain, over a period of months. Axonal transport is functionally perturbed at sites associated with local inflammation and 'damaged' myelin. Surprisingly, where demyelination is complete, naked axons appear well preserved despite a significant reduction of axonal transport. Our results suggest that neuroinflammation and/or oligodendrocyte dysfunction are more deleterious for axonal health than demyelination per se, at least in the short ter

Ultraviolet writing of channel waveguides in proton-exchanged LiNbO₃

We report on a direct ultraviolet (UV) writing method for the fabrication of channel waveguides at 1.55 µm in LiNbO3 through UV irradiation of surface and buried planar waveguides made by annealed proton exchange and reverse proton exchange. A systematic study of the guidance properties as a function of the UV writing conditions is presented

Finding Data Should be Easier than Finding Oil

The competitiveness of modern enterprises heavily depends on their ability to make the right business decisions by relying on efficient and timely analysis of the right business critical data. In large and data intensive companies such as Equinor, a Norwegian multinational oil and gas company with more than 20,000 employees, gathering such data is not a trivial task due to the growing size and complexity of corporate information sources. As a result, the data gathering task is often the most time-consuming part of the decision making process, in particular when it comes to the work processes of Equinor's exploration geologists that should find in a timely manner new exploitable accumulations of oil or gas in given areas by analysing data about these areas. In this work we present our experience in addressing this data challenge tast at Equinor. We have developed and deployed at Equinor a semantic data access system that relies on the Ontology Based Data Access (OBDA) approach. Our system is based on our solid theoretical contributions and has been extensively evaluated at Equinor

Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia

Oligodendrocytes are critical for the development of the plasma membrane and cytoskeleton of the axon. In this paper, we show that fast axonal transport is also dependent on the oligodendrocyte. Using a mouse model of hereditary spastic paraplegia type 2 due to a null mutation of the myelin Plp gene, we find a progressive impairment in fast retrograde and anterograde transport. Increased levels of retrograde motor protein subunits are associated with accumulation of membranous organelles distal to nodal complexes. Using cell transplantation, we show categorically that the axonal phenotype is related to the presence of the overlying Plp null myelin. Our data demonstrate a novel role for oligodendrocytes in the local regulation of axonal function and have implications for the axonal loss associated with secondary progressive multiple sclerosis

In Situ X-ray Absorption Spectroscopy of Metal/Nitrogen-doped Carbons in Oxygen Electrocatalysis

Metal/nitrogen-doped carbons (M−N−C) are promising candidates as oxygen electrocatalysts due to their low cost, tunable catalytic activity and selectivity, and well-dispersed morphologies. To improve the electrocatalytic performance of such systems, it is critical to gain a detailed understanding of their structure and properties through advanced characterization. In situ X-ray absorption spectroscopy (XAS) serves as a powerful tool to probe both the active sites and structural evolution of catalytic materials under reaction conditions. In this review, we firstly provide an overview of the fundamental concepts of XAS and then comprehensively review the setup and application of in situ XAS, introducing electrochemical XAS cells, experimental methods, as well as primary functions on catalytic applications. The active sites and the structural evolution of M−N−C catalysts caused by the interplay with electric fields, electrolytes and reactants/intermediates during the oxygen evolution reaction and the oxygen reduction reaction are subsequently discussed in detail. Finally, major challenges and future opportunities in this exciting field are highlighted.</p

Interactions among mitochondrial proteins altered in glioblastoma

Mitochondrial dysfunction is putatively central to glioblastoma (GBM) pathophysiology but there has been no systematic analysis in GBM of the proteins which are integral to mitochondrial function. Alterations in proteins in mitochondrial enriched fractions from patients with GBM were defined with label-free liquid chromatography mass spectrometry. 256 mitochondrially-associated proteins were identified in mitochondrial enriched fractions and 117 of these mitochondrial proteins were markedly (fold-change &#8805;2) and significantly altered in GBM (p &#8804; 0.05). Proteins associated with oxidative damage (including catalase, superoxide dismutase 2, peroxiredoxin 1 and peroxiredoxin 4) were increased in GBM. Protein–protein interaction analysis highlighted a reduction in multiple proteins coupled to energy metabolism (in particular respiratory chain proteins, including 23 complex-I proteins). Qualitative ultrastructural analysis in GBM with electron microscopy showed a notably higher prevalence of mitochondria with cristolysis in GBM. This study highlights the complex mitochondrial proteomic adjustments which occur in GBM pathophysiology

Reduced Ordered Binary Decision Diagram with Implied Literals: A New knowledge Compilation Approach

Knowledge compilation is an approach to tackle the computational intractability of general reasoning problems. According to this approach, knowledge bases are converted off-line into a target compilation language which is tractable for on-line querying. Reduced ordered binary decision diagram (ROBDD) is one of the most influential target languages. We generalize ROBDD by associating some implied literals in each node and the new language is called reduced ordered binary decision diagram with implied literals (ROBDD-L). Then we discuss a kind of subsets of ROBDD-L called ROBDD-i with precisely i implied literals (0 \leq i \leq \infty). In particular, ROBDD-0 is isomorphic to ROBDD; ROBDD-\infty requires that each node should be associated by the implied literals as many as possible. We show that ROBDD-i has uniqueness over some specific variables order, and ROBDD-\infty is the most succinct subset in ROBDD-L and can meet most of the querying requirements involved in the knowledge compilation map. Finally, we propose an ROBDD-i compilation algorithm for any i and a ROBDD-\infty compilation algorithm. Based on them, we implement a ROBDD-L package called BDDjLu and then get some conclusions from preliminary experimental results: ROBDD-\infty is obviously smaller than ROBDD for all benchmarks; ROBDD-\infty is smaller than the d-DNNF the benchmarks whose compilation results are relatively small; it seems that it is better to transform ROBDDs-\infty into FBDDs and ROBDDs rather than straight compile the benchmarks.Comment: 18 pages, 13 figure

Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

Human genetic factors predispose to tuberculosis (TB). We studied 7.6 million genetic variants in 5,530 people with pulmonary TB and in 5,607 healthy controls. In the combined analysis of these subjects and the follow-up cohort (15,087 TB patients and controls altogether), we found an association between TB and variants located in introns of the ASAP1 gene on chromosome 8q24 (P = 2.6 × 10−11 for rs4733781; P = 1.0 × 10−10 for rs10956514). Dendritic cells (DCs) showed high ASAP1 expression that was reduced after Mycobacterium tuberculosis infection, and rs10956514 was associated with the level of reduction of ASAP1 expression. The ASAP1 protein is involved in actin and membrane remodeling and has been associated with podosomes. The ASAP1-depleted DCs showed impaired matrix degradation and migration. Therefore, genetically determined excessive reduction of ASAP1 expression in M. tuberculosis–infected DCs may lead to their impaired migration, suggesting a potential mechanism of predisposition to TB