Can culture beat Covid-19? Evidence that exposure to facemasks with cultural symbols increases solidarity

Facemasks have become integral to everyday life. We propose that exposure to facemasks with a solidarity-related cultural symbol can activate cultural values such as mutual trust and increase corresponding interpersonal perceptions, thereby enhancing collective resilience in the Covid-19 pandemic. In three (two of which preregistered) studies, we examined whether exposure to facemasks with a solidarity-related cultural symbol predicts positive interpersonal perceptions, and whether this depends on death awareness. Across studies, exposure to facemasks with a cultural symbol (either pride flag or National Health Service) increased positive interpersonal perceptions, an index of solidarity, in people for whom this symbol represents a meaningful social identity. This was found whether participants were reminded of death, a neutral experience, or a negative experience. Importantly, in Study 3, exposure to facemasks with a solidarity-related cultural symbol (vs. surgical) led to greater increases in positive interpersonal perceptions when death awareness was high. Together, our findings suggest that wearing facemasks with a cultural symbol that relates to solidarity can be a vehicle for shaping people's personality impressions of others. Applied directions for the activation of people's social identities via facemask selection to promote collective resilience in the Covid-19 pandemic are discussed

Short-term PsychoEducation for Carers To Reduce Over Medication of people with intellectual disabilities (SPECTROM): study protocol

Introduction Psychotropic medications that are primarily licenced for the treatment of psychiatric disorders are used widely (32%–85%) among people with intellectual disabilities (ID) often for the management of problem (challenging) behaviour in the absence of a psychiatric disorder. Care staff play a pivotal role in the prescribing process. Currently, no staff training programme exists to address the issue of overprescribing of psychotropic medication in people with ID, thus highlighting an urgent need for developing a psychoeducational programme (PEP) specifically designed to address this issue. We propose to develop a PEP for care staff using the methodology described in the UK Medical Research Council guide for complex interventions. Methods and analysis The development of the PEP will involve (1) gathering information on available relevant training programmes, (2) running four focus groups with care staff and other professionals to establish the content and format of the PEP, and (3) organising a co-design event involving all relevant stakeholders to discuss the format of the PEP. A core project team will develop the PEP under guidance from the PEP Development Group which will consist of 10–12 relevant stakeholder representatives. Feedback from selected stakeholders on a draft PEP will allow us to refine the PEP before implementation. The PEP will have web-based modules supplemented by face to face training sessions. When the final draft is ready, we will field test the PEP on six to eight care staff from community care homes for people with ID. After completing the field test, we will run a focus group involving participants in the PEP to get feedback on the PEP. Ethics and dissemination Ethics approval for this study was waived by the UK Health Regulatory Authority as the study does not collect any patient related information and only include care staff outside the UK NHS. This will be the first ever such universally freely available PEP supported by training manual and slides

Gambaran Perilaku Pencarian Pengobatan Penyakit Tuberkulosis (TB) pada Masyarakat di Wilayah Kerja Puskesmas Uitao Kecamatan Semau Kabupaten Kupang

Treatment-seeking behavior can be seen as a reflection of the implementation of the national health system and access to health services. In the context of treatment-seeking behavior in Indonesia, the use of national health facilities. Health seeking behavior or health seeking behavior, most Indonesians will try to treat themselves first by using medicines bought at kiosks without a doctor's prescription or using traditional ingredients in the surrounding environment and even asking a traditional healer for help. If they are not successful then they go to a medical health service place, this is because Indonesia has sources of treatment covering three interconnected sectors, namely self-medication (self-medication), medical treatment and traditional medicine. However, treatment is not only conventional in nature, there are alternative treatments that are popular with the community, especially in countries rich in culture and beliefs such as Indonesia. type of research used in this research is descriptive research with a quantitative approach. This study uses a descriptive approach with the aim of describing the object of research or research results. the sampling technique using total sampling. a sample size of 209 respondents. The results showed that treatment-seeking behavior at health facilities was 41.2%, while other treatments were 58.8%. poor knowledge about TB 54.4% compared to respondents with good knowledge about TB 45.6%. positive attitude towards TB treatment was 38.2% smaller than negative attitude 61.8%. Good belief in TB treatment-seeking behavior was 36.8% smaller than bad belief about TB treatment 63.2%

Ethical prescribing of psychotropic medications for people with neurodevelopmental disorders

Objectives People with neurodevelopmental disorders (NDDs) such as intellectual and developmental disabilities (IDD) and autism are subjected to restrictive practices like physical restraint and the overuse of psychotropic medications for challenging behaviour in the absence of a psychiatric disorder. This practice may lead to human rights violations. Rational and evidence-based shared decision-making for person-centred planning will help reduce this practice. Methods We have discussed in this paper the issue of the overmedication of people with NDD, explaining how this practice may violate the United Nations (UN) Convention on the Rights of Persons with Disabilities (CRPD). Results We have discussed how the following UN CRPD Articles may be affected by overmedication, including Article 15 (degrading treatment or punishment), 16 (abuse), 17 (the integrity of the person), and 25 (health). The other Articles that may be indirectly affected by this practice are 5 (equality and non-discrimination), 9 (accessibility), 19 (independent living and community inclusion), 21 (access to information), 24 (education), 26 (rehabilitation), 27 (work and employment), 28 (adequate living standard), and 30 (participation in recreation and leisure). Conclusions Overmedication of people with NDD, particularly the off-licence use of psychotropics for challenging behaviour, the side effects of these medications impacting the person’s quality of life are likely to violet several UN Articles on Rights of Persons with Disabilities. Following the right guidelines may help reduce these human rights violations

Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue

Despite the substantial impact of skin scarring on patients and the healthcare system, there is a lack of strategies to prevent scar formation, let alone methods to remodel mature scars. Here, we took a unique approach inspired by how healthy hairbearing skin undergoes physiological remodelling during the regular cycling of hair follicles. In this pilot clinical study, we tested if hair follicles transplanted into human scars can facilitate tissue regeneration and actively remodel fibrotic tissue, similar to how they remodel the healthy skin. We collected full-thickness skin biopsies and compared the morphology and transcriptional signature of fibrotic tissue before and after transplantation. We found that hair follicle tranplantation induced an increase in the epidermal thickness, interdigitation of the epidermal-dermal junction, dermal cell density, and blood vessel density. Remodelling of collagen type I fibres reduced the total collagen fraction, the proportion of thick fibres, and their alignment. Consistent with these morphological changes, we found a shift in the cytokine milieu of scars with a long-lasting inhibition of pro-fibrotic factors TGFβ1, IL13, and IL-6. Our results show that anagen hair follicles can attenuate the fibrotic phenotype, providing new insights for developing regenerative approaches to remodel mature scars

Analisis Faktor Keteraturan Ibu dalam Menimbang Balita di Posyandu

Mothers’ regularity of weighing their children aged <5 yo at Posyandu is crucial to monitor the growth, nutritional status, and health of the children. Several factors could affect mothers’ regularity in weighing their children at Posyandu. This study aimed to identify factors affecting mothers to regularly measure the weight of their children <5 yo at Posyandu in Toobaun Village Kupang District. The study used an analytical survey with a cross-sectional study design. The sample was 57 mothers who had under-five children obtained by simple random sampling technique. Data were collected through interviews using questionnaires and analyzed using the chi-square test. The result showed that knowledge (p= 0,002) and distance home-posyandu (p=0,000) associated with mothers’ regularity of weighing their under-five children, while mother’s occupation had no association with mothers’ regularity of weighing their children( p=0,091). Health workers should encourage mothers to measure regularly the weight of their under-five children at Posyandu

Spatial patterns of zooplankton distribution and abundance in relation to phytoplankton, fish catch and some water quality parameters at Shirati bay, lake victoria-Tanzania

Spatial patterns and abundance of zooplankton in aquatic habitats are important determinants for production of fish species, invertebrates and availability of phytoplankton. Weekly monitoring for zooplankton abundance was conducted in Shirati Bay, Lake Victoria, to explore their spatial patterns in relation to phytoplankton, fish catch and some water quality parameters. The vertical distribution of zooplankton was generally higher close to the bottom as compared to surface waters of the lake. Zooplankton vertical distribution positively correlated with water transparency (r = 0.680, p = 0.011). The horizontal abundance of zooplankton was not significantly different amongst the three stations (p = 0.5143). While Copepoda was the dominant group in terms of composition, Rotifera had the highest diversity indices of all the zooplankton groups obtained. The abundance of nauplius larvae was significantly higher than that of the copepodites (p = 0.022). Nile perch, Lates niloticus dominated the total catches (47%) followed by Nile tilapia, Oreochromis niloticus (29%) and haplochromines (21%). The abundance of haplochromines and juvenile fishes correlated significantly with the abundance of zooplankton (r = 0.856, p = 0.002 and r = 0.58, p = 0.038, respectively). The current study revealed that zooplankton vertical distribution at Shirati Bay is mainly controlled by water transparency and predation by juvenile Nile perch, Nile tilapia and haplochromines.Keywords: chlorophyll-a; calanoid; cyclopoid; nauplius larvae; juvenile fis

UK psychiatrists' experience of withdrawal of antipsychotics prescribed for challenging behaviours in adults with intellectual disabilities and/or autism.

BACKGROUND: A high proportion of adults with intellectual disabilities are prescribed off-licence antipsychotics in the absence of a psychiatric illness. The National Health Service in England launched an initiative in 2016, 'Stopping over-medication of people with a learning disability [intellectual disability], autism or both' (STOMP), to address this major public health concern. AIMS: To gain understanding from UK psychiatrists working with adults with intellectual disabilities on the successes and challenges of withdrawing antipsychotics for challenging behaviours. METHOD: An online questionnaire was sent to all UK psychiatrists working in the field of intellectual disability (estimated 225). RESULTS: Half of the 88 respondents stated that they started withdrawing antipsychotics over 5 years ago and 52.3% stated that they are less likely to initiate an antipsychotic since the launch of STOMP. However, since then, 46.6% are prescribing other classes of psychotropic medication instead of antipsychotics for challenging behaviours, most frequently the antidepressants. Complete antipsychotic discontinuation in over 50% of patients treated with antipsychotics was achieved by only 4.5% of respondents (n = 4); 11.4% reported deterioration in challenging behaviours in over 50% of patients on withdrawal and the same proportion (11.4%) reported no deterioration. Only 32% of respondents made the diagnosis of psychiatric illness in all their patients themselves. Family and paid carers' concern, lack of multi-agency and multidisciplinary input and unavailability of non-medical psychosocial intervention are key reported factors hampering the withdrawal attempt. CONCLUSIONS: There is an urgent need to develop national guidelines to provide a framework for systematic psychotropic drug reviews and withdrawal where possible

Size constancy mechanisms: empirical evidence from touch

Several studies have shown the presence of large anisotropies for tactile distance perception across several parts of the body. Tactile distance between two touches on the dorsum of the hand is perceived as larger when they are oriented mediolaterally (across the hand) than proximo-distally (along the hand). This effect can be partially explained by the characteristics of primary somatosensory cortex representations. However, this phenomenon is significantly attenuated relative to differences in acuity and cortical magnification suggesting a process of tactile size constancy. It is unknown whether the same kind of compensation takes place also when estimating the size of a continuous object. Here, we investigated whether the tactile anisotropy that typically emerges when participants have to estimate the distance between two touches is also present when a continuous object touches the skin and participants have to estimate its size. In separate blocks, participants judged which of two tactile distances or objects on the dorsum of their hand felt larger. One stimulation (first or second) was aligned with the proximo-distal axis (along the hand), the other with the mediolateral axis (across the hand). Results showed a clear anisotropy for distances between two distinct points, with across distances consistently perceived as larger than along distance, as in previous studies. Critically, however, this bias was significantly reduced or absent for judgments of the length of continuous objects. These results suggest that a tactile size constancy process is more effective when the tactile size of an object has to be approximated compared to when the distance between two touches has to be determined. The possible mechanism subserving these results is described and discussed. We suggest that a lateral inhibition mechanism, when an object touches the skin, provides information through the distribution of the inhibitory subfields of the RF about the shape of the tactile RF itself. Such process allows an effective tactile size compensatory mechanism where a good match between the physical and perceptual dimension of the object is achieved