A Novel Constraint Narrowing Technique for MIMO Unstable System

Frequency response data collection can be a boon for modeling of MIMO uncertain plant. System stability can be assessed either by transfer function or by state-space method. Both will arrive at matrix transformation and further decision approach. Both can be considered for diagonalization of matrix. It is a proven fact that when the matrix is diagonalized the elements of the principle diagonal are the Eigen values and these Eigen values are closed loop poles from which stability can be assessed. The feature of such a diagonal matrix is that its principle diagonal elements contain gains of all the feedback paths. Singular value decomposition is used here for diagonalization. Singular value decomposition technique has been demonstrated by many authors but, application of PCA with Euclidian norm has not been paid attention so far. The systems numerical array is fed to a digital processing tool such as Mat lab and SVD-PCA (Singular Value Decomposition- Principal Component Analysis) is applied to determine the reduction of disturbance or noise and to provide minimum sensitivity and error correction. There are Hull, Box and KB consistency narrowing techniques used previously and the idea is extended further and an SVD-PCA-Norm technique which is now referred as LA criteria has been demonstrated here

Experimental investigation of steel equal angle subjected to compression

This paper presents pin-ended compression tests on steel equal angles. Three nominal section sizes were tested. Detailed measurements of material properties, residual stresses, and geometrical imperfections were conducted. The pin ended specimens were tested with a minimal eccentricity of L/1,000 applied about the minor axis to cause compression at the tips of the legs. The test data are compared with the Indian specifications for hot-rolled steel structures. The section capacities obtained from the column tests are found to be between 15 and 40% higher than those calculated according to the specifications. It is concluded that there is no need to include the additional eccentricity specified in the steel structures standards accounting for the shift of the effective centroid, and that the eccentricity of L/1,000, specified for all section classes, should be applied to slender sections only

Analysis of steel I-beams with rectangular web openings: experimental and finite element investigation

Steel I-shaped beams with web openings of shapes like hexagonal, circular and rectangular at regular intervals have been used since last 60–70 years. Therefore aim of this paper is to examine the behaviour of steel I-beams with rectangular web openings by performinganexperimental and parametric study. A parametric study based on finite element analysis consists of effect of fillet radius, aspect ratio of rectangular openings, stiffeners position around the openings and effect of positions of openings on load carrying capacities of steel beam with rectangular web openings was carried out by using a commercial finite element software ANSYS v.12. An overall study of such type of beam was carried out and results shows that rectangular openings having fillet radius either 2 times thickness of web or 25 mm (whichever is minimum), aspect ratio of 1.6 and reinforcement either in the form of horizontal or vertical stiffeners around the web openings found to be very effective. The fillet radius and stiffeners also affect the stress distribution around the corner regions of openings. Load carrying capacities of perforated beams are almost equal to plain-webbed beams, when openings are placed within middle two-third(neutral zone) of the span

Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats

Organophosphate (OP) chemicals include commonly used pesticides and chemical warfare agents, and mechanistically they are potent inhibitors of the cholinesterase (ChE) enzyme. Epidemiological studies report long-term neuropsychiatric issues, including depression and cognitive impairments in OP-exposed individuals. Chlorpyrifos (CPF) is one of the most widely used pesticides worldwide. Multiple laboratory studies have reported on either the long-term behavioral effect of an acute high-dose CPF (30-250 mg/kg) or studied sub-chronic behavioral effects, particularly the motor and cognitive effects of repeated low-dose CPF. However, studies are lacking on chronic mood and depression-related morbidities following repeated CPF doses that would mimic occupationally relevant OP exposures. In this study, adult male rats were injected with CPF (1, 3, 5, or 10 mg/kg/d, s.c.) for 21 consecutive days. Dependent on the CPF dose, ChE activity was inhibited approximately 60-80% in the blood and about 20-50% in the hippocampus at 2-days after the end of CPF exposures. Following a 12-week washout period, a complete recovery of ChE activity was noted. However, CPF-treated rats exhibited a dose-dependent increase in signs related to anhedonia (sucrose preference test), anxiety (open-field and elevated plus-maze), and despair (forced swim test) at this stage. To the best of our knowledge, this could be the first laboratory study that demonstrates a cause-effect relationship between occupational-like CPF exposures in adult rats and the development of long-term depression-related outcomes and could provide an experimental system to study molecular mechanisms underlying environmental OP exposures and the elevated risk for chronic behavioral deficits

GADMS: Gathering Aggregated Data using Mobile Sink in Wireless Sensor Networks

WSNs consist of resource constrained sensor nodes that monitor the physical environment and transmit their data to the Sink through multi-hop communication. Mobile sinks are used to reduce the number of hops the data travels and thereby reducing the overall energy consumption. In this paper we propose Gathering Aggregated Data using Mobile Sink in Wireless Sensor Networks (GADMS) protocol that allows the mobile sink to collect data from WSNs where path of the mobile sink is not predetermined. The mobile sink halts at a point in the network and broadcasts an aggregate query. The average path length of a data packet is a constant and hence it can withstand node failures. The performance analysis shows that GADMS incurs less energy consumption and improved packet delivery ratio in comparison to SinkTrail.

Salivary Gland Neoplasms in Indian Paediatric Population Visiting a Dental Institution

INTRODUCTION: With a probability of 50% malignancy, salivary gland tumors are not too commonly noticed in children and adolescents. Most of these have idiopathic etiology but a few pre-disposing factors have been reported in literature. We hereby report eighteen cases of paediatric salivary gland tumors in a study conducted from September 2013 to August 2018 at department of Oral and maxillofacial surgery at Tatyasaheb Kore Dental college and Research Centre, Kohlapur, Maharashtra, India..AIM & OBJECTIVES: This study aimed to inspect the distribution, clinical and histopathological features of salivary gland tumours in children and adolescents.MATERIAL AND METHODS: A total of 18 cases of salivary gland tumors encountered in paediatric age group were studied and explored for age, gender, site proneness and for histopathological nature.RESULTS: Female gender had a predominance over males. Parotid tumors were more common (77.78%) as compared to tumors of submandibular glands. Six cases were diagnosed with benign tumors (pleomorphic adenoma) and rest had malignant tumors (mucoepidermoid in nature). Majority of the cases did not report undergoing any prior treatment.CONCLUSION Present study revealed that salivary gland tumors in paediatric age group are quite rare with female gender being more prone. With majority of cases being mucoepidermoid in nature, parotid gland is most commonly affected

Salivary Gland Neoplasms in Indian Paediatric Population Visiting a Dental Institution

INTRODUCTION: With a probability of 50% malignancy, salivary gland tumors are not too commonly noticed in children and adolescents. Most of these have idiopathic etiology but a few pre-disposing factors have been reported in literature. We hereby report eighteen cases of paediatric salivary gland tumors in a study conducted from September 2013 to August 2018 at department of Oral and maxillofacial surgery at Tatyasaheb Kore Dental college and Research Centre, Kohlapur, Maharashtra, India..AIM & OBJECTIVES: This study aimed to inspect the distribution, clinical and histopathological features of salivary gland tumours in children and adolescents.MATERIAL AND METHODS: A total of 18 cases of salivary gland tumors encountered in paediatric age group were studied and explored for age, gender, site proneness and for histopathological nature.RESULTS: Female gender had a predominance over males. Parotid tumors were more common (77.78%) as compared to tumors of submandibular glands. Six cases were diagnosed with benign tumors (pleomorphic adenoma) and rest had malignant tumors (mucoepidermoid in nature). Majority of the cases did not report undergoing any prior treatment.CONCLUSION Present study revealed that salivary gland tumors in paediatric age group are quite rare with female gender being more prone. With majority of cases being mucoepidermoid in nature, parotid gland is most commonly affected

Priprava i vrednovanje biorazgradljivih implantata s kontroliranim oslobađanjem za postoperativnu primjenu

Biodegradable implants of ciprofloxacin hydrochloride for post operative site delivery were prepared using glyceryl monostearate and different concentrations of polyethylene glycol (PEG 6000) glycerol and Tween 80 as erosion enhancers by compression and molding technique. Formulations were subjected to in vitro drug release by the USP dissolution method, while promising formulations were subjected to in vitro drug release by the agar gel method and also to stability studies. It was observed that glyceryl monostearate formed hydrophobic matrix and delayed the drug delivery. Antibiotic release profile was controlled by using different combinations of erosion enhancers. The formulation prepared by compression method showed more delayed release as compared to formulations prepared by molding method.Biorazgradljivi implantati ciprofloksacin hidroklorida za postoperativnu primjenu pripravljeni su pomoću gliceril monostearata (GMS) i različitih koncentracija polietilen glikola (PEG 6000), glicerola i Tween 80 kao promotora erozije metodom kompresije i lijevanja. Oslobađanje ljekovite tvari iz pripravaka praćeno je in vitro prema USP metodi. Pripravci koji su dali dobre rezultate ispitani su i in vitro metodom s agarom te su podvrgnuti testovima stabilnosti. Primijećeno je da gliceril monostearat tvori hidrofobni matriks i usporava oslobađanje lijeka. Koristeći različite kombinacije promotora erozije postignuto je kontrolirano oslobađanje antibiotika. Oslobađanje iz implantata dobivenih metodom kompresije sporije je od implantata dobivenih metodom lijevanja