9,043 research outputs found
Model of aircraft noise adaptation
Development of an aircraft noise adaptation model, which would account for much of the variability in the responses of subjects participating in human response to noise experiments, was studied. A description of the model development is presented. The principal concept of the model, was the determination of an aircraft adaptation level which represents an annoyance calibration for each individual. Results showed a direct correlation between noise level of the stimuli and annoyance reactions. Attitude-personality variables were found to account for varying annoyance judgements
Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin.
A yearlong study was performed to examine the effect of antibiotic administration on the bacterial gut flora. Gram-negative facultative anaerobic bacteria were recovered from the feces of healthy adult volunteers administered amoxicillin, minocycline or placebo, and changes determined in antimicrobial resistance (AMR) gene carriage. Seventy percent of the 1039 facultative anaerobic isolates recovered were identified by MALDI-TOF as Escherichia coli. A microarray used to determine virulence and resistance gene carriage demonstrated that AMR genes were widespread in all administration groups, with the most common resistance genes being bla TEM, dfr, strB, tet(A), and tet(B). Following amoxicillin administration, an increase in the proportion of amoxicillin resistant E. coli and a three-fold increase in the levels of bla TEM gene carriage was observed, an effect not observed in the other two treatment groups. Detection of virulence genes, including stx1A, indicated not all E. coli were innocuous commensals. Approximately 150 E. coli collected from 6 participants were selected for pulse field gel electrophoresis (PFGE), and a subset used for characterisation of plasmids and Phenotypic Microarrays (PM). PFGE indicated some E. coli clones had persisted in volunteers for up to 1 year, while others were transient. Although there were no unique characteristics associated with plasmids from persistent or transient isolates, PM assays showed transient isolates had greater adaptability to a range of antiseptic biocides and tetracycline; characteristics which were lost in some, but not all persistent isolates. This study indicates healthy individuals carry bacteria harboring resistance to a variety of antibiotics and biocides in their intestinal tract. Antibiotic administration can have a temporary effect of selecting bacteria, showing co-resistance to multiple antibiotics, some of which can persist within the gut for up to 1 year
Suprathermal electrons at Saturn's bow shock
The leading explanation for the origin of galactic cosmic rays is particle
acceleration at the shocks surrounding young supernova remnants (SNRs),
although crucial aspects of the acceleration process are unclear. The similar
collisionless plasma shocks frequently encountered by spacecraft in the solar
wind are generally far weaker (lower Mach number) than these SNR shocks.
However, the Cassini spacecraft has shown that the shock standing in the solar
wind sunward of Saturn (Saturn's bow shock) can occasionally reach this
high-Mach number astrophysical regime. In this regime Cassini has provided the
first in situ evidence for electron acceleration under quasi-parallel upstream
magnetic conditions. Here we present the full picture of suprathermal electrons
at Saturn's bow shock revealed by Cassini. The downstream thermal electron
distribution is resolved in all data taken by the low-energy electron detector
(CAPS-ELS, <28 keV) during shock crossings, but the higher energy channels were
at (or close to) background. The high-energy electron detector (MIMI-LEMMS, >18
keV) measured a suprathermal electron signature at 31 of 508 crossings, where
typically only the lowest energy channels (<100 keV) were above background. We
show that these results are consistent with theory in which the "injection" of
thermal electrons into an acceleration process involves interaction with
whistler waves at the shock front, and becomes possible for all upstream
magnetic field orientations at high Mach numbers like those of the strong
shocks around young SNRs. A future dedicated study will analyze the rare
crossings with evidence for relativistic electrons (up to ~1 MeV).Comment: 22 pages, 5 figures. Accepted for publication in Ap
Practitioner review: pathways to care for ADHD - a systematic review of barriers and facilitators
Background. Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder starting in childhood that may persist into adulthood. It can be managed through carefully monitored medication and nonpharmacological interventions. Access to care for children at risk of ADHD varies both within and between countries. A systematic literature review was conducted to investigate the research evidence related to factors which influence children accessing services for ADHD
Journeys from the east: the popular geopolitics of film motivated Chinese tourism
Over the past five years the number of outbound travellers from the People's Republic of China (PRC) doubled, making Chinese tourists the largest group of international travellers in the world. Drawing on media reports of the impact of box office hits on Chinese outbound tourism, we explore how popular cinema informs the Chinese tourism boom's impact on the everyday geopolitics of Sino-host tourism encounters. Through a critical discourse analysis of representations of tourism practices in Chinese film, we highlight key tropes of economic and political power that present touristic practices as imaginable, aspirational, and attainable. We then examine how actual tourism encounters compare to their onscreen imaginaries. Drawing on theoretical and methodological insights from film studies, political anthropology and geography, this article contributes to emerging multi-disciplinary work on how filmic representations of Chinese tourism mediates the ongoing rearticulation of geopolitics within what has been dubbed the 'Chinese Century'
SuperNeurons: Dynamic GPU Memory Management for Training Deep Neural Networks
Going deeper and wider in neural architectures improves the accuracy, while
the limited GPU DRAM places an undesired restriction on the network design
domain. Deep Learning (DL) practitioners either need change to less desired
network architectures, or nontrivially dissect a network across multiGPUs.
These distract DL practitioners from concentrating on their original machine
learning tasks. We present SuperNeurons: a dynamic GPU memory scheduling
runtime to enable the network training far beyond the GPU DRAM capacity.
SuperNeurons features 3 memory optimizations, \textit{Liveness Analysis},
\textit{Unified Tensor Pool}, and \textit{Cost-Aware Recomputation}, all
together they effectively reduce the network-wide peak memory usage down to the
maximal memory usage among layers. We also address the performance issues in
those memory saving techniques. Given the limited GPU DRAM, SuperNeurons not
only provisions the necessary memory for the training, but also dynamically
allocates the memory for convolution workspaces to achieve the high
performance. Evaluations against Caffe, Torch, MXNet and TensorFlow have
demonstrated that SuperNeurons trains at least 3.2432 deeper network than
current ones with the leading performance. Particularly, SuperNeurons can train
ResNet2500 that has basic network layers on a 12GB K40c.Comment: PPoPP '2018: 23nd ACM SIGPLAN Symposium on Principles and Practice of
Parallel Programmin
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