234 research outputs found
Análise da identidade, dependência e produção das Unidades de Pesquisa da UNLP
In this work, an analysis of various components of the Research function of the National University of La Plata (UNLP) is carried out in order to lay the foundations for the construction of a control panel on the monitoring of policies, programs and management decisions. In this area of strategic complexity For this purpose, an organization chart of the Research Units (UIs) is presented together with other cartographies regarding identity, institutional dependency and disciplinary fields, analyzing them qualitatively and preliminarily from their own indicators, constructed with such end. Some reflections and proposals are made for the management and planning levels of the institutional network of science and technology of a large Argentine university such as UNLP.En el presente trabajo se realiza un análisis de diversos componentes de la función Investigación de la Universidad Nacional de La Plata (UNLP) a fin de sentar las bases para la construcción de un tablero de control sobre el seguimiento de políticas, programas y decisiones de gestión en este área de complejidad estratégica A tal efecto se presenta un organigrama de las Unidades de Investigación (UIs) junto con otras cartografías respecto a la identidad, dependencia institucional y a los campos disciplinares, analizándolas cualitativa y preliminarmente a partir de indicadores propios, construidos con tal fin. Se hacen algunas reflexiones y propuestas de andariveles de gestión y planificación de la red institucional de ciencia y técnica de una universidad argentina de gran dimensión como la UNLP.Neste trabalho, é realizada uma análise de vários componentes da função de Pesquisa da Universidade Nacional de La Plata (UNLP) com o objetivo de lançar as bases para a construção de um painel de controle sobre o monitoramento de políticas, programas e decisões de gestão. nesta área de complexidade estratégica Para tanto, é apresentado um organograma das Unidades de Pesquisa (IUs) em conjunto com outras cartografias sobre identidade, dependência institucional e campos disciplinares, analisando-os qualitativa e preliminarmente a partir de seus próprios indicadores, construídos com tal fim. São feitas algumas reflexões e propostas para os níveis de gestão e planejamento da rede institucional de ciência e tecnologia de uma grande universidade argentina como a UNLP
Freight distribution performance indicators for service quality planning in large transportation networks
This paper studies the use of performance indicators in routing problems to estimate how transportation cost is affected by the quality of service offered. The quality of service is assumed to be directly dependent on the size of the time windows. Smaller time windows mean better service. Three performance indicators are introduced. These indicators are calculated directly from the data without the need of a solution method. The introduced indicators are based mainly on a "request compatibility", which describes whether two visits can be scheduled consecutively in a route. Other two indicators are introduced, which get their values from a greedy constructive heuristic. After introducing the indicators, the correlation between indicators and transportation cost is examined. It is concluded that the indicators give a good first estimation on the transportation cost incurred when providing a certain quality of service. These indicators can be calculated easily in one of the first planning steps without the need of a sophisticated solution tool. The contribution of the paper is the introduction of a simple set of performance indicators that can be used to estimate the transportation cost of a routing problem with time window
Performance evaluation of scheduling policies for the DRCMPSP
In this study, we consider the dynamic resource-constrained multi-project scheduling problem (DRCMPSP) where projects generate rewards at their completion, completions later than a due date cause tardiness costs and new projects arrive randomly during the ongoing project execution which disturbs the existing project scheduling plan. We model this problem as a discrete Markov decision process and explore the computational limitations of solving the problem by dynamic programming. We run and compare four different solution approaches on small size problems. These solution approaches are: a dynamic programming algorithm to determine a policy that maximises the average profit per unit time net of charges for late project completion, a genetic algorithm which generates a schedule to maximise the total reward of ongoing projects and updates the schedule with each new project arrival, a rule-based algorithm which prioritise processing of tasks with the highest processing durations, and a worst decision algorithm to seek a non-idling policy to minimise the average profit per unit time. Average profits per unit time of generated policies of the solution algorithms are evaluated and compared. The performance of the genetic algorithm is the closest to the optimal policies of the dynamic programming algorithm, but its results are notably suboptimal, up to 67.2\%. Alternative scheduling algorithms are close to optimal with low project arrival probability but quickly deteriorate their performance as the probability increases
Under the Skin of a Lion: Unique Evidence of Upper Paleolithic Exploitation and Use of Cave Lion (Panthera spelaea) from the Lower Gallery of La Garma (Spain)
ABSTRACT: Pleistocene skinning and exploitation of carnivore furs have been previously inferred from archaeological evidence. Nevertheless, the evidence of skinning and fur processing tends to be weak and the interpretations are not strongly sustained by the archaeological record. In the present paper, we analyze unique evidence of patterned anthropic modification and skeletal representation of fossil remains of cave lion (Panthera spelaea) from the Lower Gallery of La Garma (Cantabria, Spain). This site is one of the few that provides Pleistocene examples of lion exploitation by humans. Our archaeozoological study suggests that lion-specialized pelt exploitation and use might have been related to ritual activities during the Middle Magdalenian period (ca. 14800 cal BC). Moreover, the specimens also represent the southernmost European and the latest evidence of cave lion exploitation in Iberia. Therefore, the study seeks to provide alternative explanations for lion extinction in Eurasia and argues for a role of hunting as a factor to take into account
Parrots Eat Nutritious Foods despite Toxins
Generalist herbivores are challenged not only by the low nitrogen and high indigestibility of their plant foods, but also by physical and chemical defenses of plants. This study investigated the foods of wild parrots in the Peruvian Amazon and asked whether these foods contain dietary components that are limiting for generalist herbivores (protein, lipids, minerals) and in what quantity; whether parrots chose foods based on nutrient content; and whether parrots avoid plants that are chemically defended.We made 224 field observations of free-ranging parrots of 17 species in 8 genera foraging on 102 species of trees in an undisturbed tropical rainforest, in two dry seasons (July-August 1992-1993) and one wet season (January-February1994). We performed laboratory analyses of parts of plants eaten and not eaten by parrots and brine shrimp assays of toxicity as a proxy for vertebrates. Parrots ate seeds, fruits, flowers, leaves, bark, and insect larvae, but up to 70% of their diet comprised seeds of many species of tropical trees, in various stages of ripeness. Plant parts eaten by parrots were rich in protein, lipid, and essential minerals, as well as potentially toxic chemicals. Seeds were higher than other plant materials in protein and lipid and lower in fiber. Large macaws of three species ate foods higher in protein and lipids and lower in fiber compared to plant parts available but not eaten. Macaws ate foods that were lower in phenolic compounds than foods they avoided. Nevertheless, foods eaten by macaws contained measurable levels of toxicity. Macaws did not appear to make dietary selections based on mineral content.Parrots represent a remarkable example of a generalist herbivore that consumes seeds destructively despite plant chemical defenses. With the ability to eat toxic foods, rainforest-dwelling parrots exploited a diversity of nutritious foods, even in the dry season when food was scarce for other frugivores and granivores
Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays
MELD score and antibiotics use are predictors of length of stay in patients hospitalized with hepatic encephalopathy
Engineers of Life? A Critical Examination of the Concept of Life in the Debate on Synthetic Biology
The concept of life plays a crucial role in the debate on synthetic biology. The first part of this chapter outlines the controversial debate on the status of the concept of life in current science and philosophy. Against this background, synthetic biology and the discourse on its scientific and societal consequences is revealed as an exception. Here, the concept of life is not only used as buzzword but also discussed theoretically and links the ethical aspects with the epistemological prerequisites and the ontological consequences of synthetic biology. The second part examines this point of intersection and analyses some of the issues which are discussed in terms of the concept of life. The third part turns to the history of the concept of life. It offers an examination of scientific and philosophical discourses on life at the turn of the 20th century and suggests a surprising result: In the light of this history, synthetic biology leads to well-known debates, arguments, notions and questions. But it is concluded that the concept of life is too ambiguous and controversial to be useful for capturing the actual practice of synthetic biology. In the fourth part I argue that with regard to the ethical evaluation of synthetic biology, the ambiguity of the concept of life is not as problematic as sometimes held because other challenges are more important. The question whether the activity of synthetic biological systems should be conceived as life or not is primarily theoretical
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