Stimulated emission and excited-state absorption at room temperature on the 550 nm-laser transition in Er3+ doped YAlO3

A pump- and probe-beam technique is used for measuring time-resolved and cw-pumped excited-state absorption (ESA) and stimulated-emission (SE) spectra of Er3+:YAlO3 with high resolution. In combination with absorption and fluorescence spectra, detailed information on the wavelengths and cross-sections of ESA and SE at the 550 nm laser transition is provided

Analysing the relationship between ectomycorrhizal infection and forest decline using marginal models

This statistical survey originates from the problem of discovering which relationship exists between root ectomycorrhizal infection and health status of forest plants. The sampling scheme takes observations from roots that come from sectors around the tree resulting in a hierarchical association structure of the observations. Marginal regression models are used to analyze the mean effect of the ectomycorrhizal state on a response variable proxy for the health degree of the plants

Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the neuronal response to neurotrophic factors in nontransformed cells. We report here that the oncogene protein T24-ras, when introduced into the cytoplasm of freshly dissociated chick embryonic neurons, promotes the in vitro survival and neurite outgrowth of nerve growth factor-responsive dorsal root ganglion neurons, brain-derived neurotrophic factor-responsive nodose ganglion neurons, and ciliary neuronotrophic factor-responsive ciliary ganglion neurons. The proto-oncogene product c-Ha-ras also promotes neuronal survival, albeit less strongly. No effect could be observed with truncated counterparts of T24-ras and c-Ha-ras lacking the 23 C-terminal amino acids including the membrane-anchoring, palmityl-accepting cysteine. These results suggest a generalized involvement of ras or ras-like proteins in the intracellular signal transduction pathway for neurotrophic factors

Re-Evaluating GermEval17 Using German Pre-Trained Language Models

The lack of a commonly used benchmark data set (collection) such as (Super-)GLUE (Wang et al., 2018, 2019) for the evaluation of non-English pre-trained language models is a severe shortcoming of current English-centric NLP-research. It concentrates a large part of the research on English, neglecting the uncertainty when transferring conclusions found for the English language to other languages. We evaluate the performance of the German and multilingual BERT-based models currently available via the huggingface transformers library on the four tasks of the GermEval17 workshop. We compare them to pre-BERT architectures (Wojatzki et al., 2017; Schmitt et al., 2018; Attia et al., 2018) as well as to an ELMo-based architecture (Biesialska et al., 2020) and a BERT-based approach (Guhr et al., 2020). The observed improvements are put in relation to those for similar tasks and similar models (pre-BERT vs. BERT-based) for the English language in order to draw tentative conclusions about whether the observed improvements are transferable to German or potentially other related languages.Comment: Accepted as a conference paper at the 6th Swiss Text Analytics Conference (SwissText), Brugg, Switzerland (Online), June 14-16, 202

Lifetime Extension, Repowering or Decommissioning? Decision Support for Operators of Ageing Wind Turbines

In Germany, more than one third of the installed wind energy capacity will leave the feed-in tariff funding between 2021 and 2025. Operators of affected turbines are therefore increasingly concerned with the design of profitable end-of-funding strategies. This requires feasibility analyses of both lifetime extension and repowering options and entails the subsequent challenge to determine the optimal lifetime extension and corresponding repowering timing. To support operators and other stakeholders dealing with wind turbines' end-of-life issues, this study presents a geographic information system that permits evaluating optimal end-of-funding strategies at different spatial scales reaching down to detailed analyses on individual turbine level. The decision support system processes topographic, wind, turbine, and finance data in an integrated system of resource simulations, spatial planning analyses and economic viability assessments. Case-study results show that a uniform end-of-funding strategy cannot be applied to all ageing turbines. Conducted sensitivity analyses rather indicate that the best strategy highly depends on various turbine-specific aspects, especially the location, type and maintenance costs as well as exogenous factors, including the developments of electricity spot market prices and tendered feed-in premiums. In light of latest trends regarding the exogenous factors, lifetime extension and repowering potentials increase. However, the results also indicate that dismantling, disposal and recycling of numerous ageing turbines will become a major challenge for the wind energy sector in the next decade. © 2019 Published under licence by IOP Publishing Ltd

Pathogenesis and Potential Strategies for Prevention and Treatment of Septic Shock: An Update

Septic shock is mediated by complex interactions of cells, cytokines, and humoral pathways. Clinical therapeutic strategies aimed at inhibiting selected pathways have been efficacious in subsets of patients. Experimental studies focusing on the activities of single cytokines have contributed to the understanding of the complex pathophysiology of septic shock. More precise delineation of the roles of each mechanism contributing to pathogenesis will permit the identification of subsets of patients who might benefit from particular therapeutic strategies and will guide the development of additional approaches to prevention and treatmen