Untersuchungen zu Fütterung, Milchleistung und Tiergesundheit von Milchkühen im Ökologischen Landbau

The breeding scheme entails yield differences of more than 2 000 kg energy corrected milk (ECM) per cow and year. On average, farms feeding less concentrate yielded slightly lower milk yields per cow and year, however, because of the longer productive life the cows showed similar milk yields over their lifetime. The farms investigated so far appeared to have healthy cows, even if fed low levels of concentrates or in the case of extremely low or high urea contents in the milk. These values could indicate the cows’ ability to compensate for short-dated changes

Kraftfuttergaben und Milchleistung bei Weidegang von Milchviehherden im ökologischen Landbau

During grazing, the efficiency of concentrate feeding on milk yields is low, especially when white clover is present in the sward (Wilkens et al., 1994). Clover in animal feed enhances forage intake; feeding trials have shown increased intake rates by 15-30 % (Paul, 2003). These results are of special interest for organic farms, where clover has a higher impact on the farming system. In the experimental organic farm of the Landwirtschaftskammer Nordrhein-Westfalen (Haus Riswick) the concentrate rate fed during grazing time showed no influence upon milk yields (2,6 resp.4,7 kg DM concentrate/ animal/day). In agreement with these results a three years investigation on 89 organic farms in Northwest Germany showed no effect of concentrate feeding on milk yield during the grazing season. Furthermore, a reduction or increase of concentrate rates during the grazing season did not show any differences in animal health so far

A Virtual Conversational Agent for Teens with Autism: Experimental Results and Design Lessons

We present the design of an online social skills development interface for teenagers with autism spectrum disorder (ASD). The interface is intended to enable private conversation practice anywhere, anytime using a web-browser. Users converse informally with a virtual agent, receiving feedback on nonverbal cues in real-time, and summary feedback. The prototype was developed in consultation with an expert UX designer, two psychologists, and a pediatrician. Using the data from 47 individuals, feedback and dialogue generation were automated using a hidden Markov model and a schema-driven dialogue manager capable of handling multi-topic conversations. We conducted a study with nine high-functioning ASD teenagers. Through a thematic analysis of post-experiment interviews, identified several key design considerations, notably: 1) Users should be fully briefed at the outset about the purpose and limitations of the system, to avoid unrealistic expectations. 2) An interface should incorporate positive acknowledgment of behavior change. 3) Realistic appearance of a virtual agent and responsiveness are important in engaging users. 4) Conversation personalization, for instance in prompting laconic users for more input and reciprocal questions, would help the teenagers engage for longer terms and increase the system's utility

Scoring Error of Social Avoidance and Distress Scale and its Psychometric Implications

An error in the scoring instructions of the Social Avoidance and Distress Scale (SAD), one of the most popular instruments to measure social anxiety, is discussed

The Validity of the Social Avoidance and Distress Scale and the Fear of Negative Evaluation Scale with Social Phobic Patients

Turner, McCanna and Beidel’s (1987) recent evaluation of the Social Avoidance and Distress Scale (SADS) and the Fear of Negative Evaluation Scale (FNE) with anxiety disordered patients concluded that the SADS and FNE lacked discriminant validity and may be inappropriate for subject selection or outcome evaluation in studies of social phobia . This paper raises some concerns with the interpretation of the data presented by Turner et al. (1987) and presents additional data from studies in our laboratories that may qualify their conclusions. It is asserted that (a) the SADS and FNE are not appropriate for diagnostic screening of social phobic patients, (b) Turner et al.’s findings may have been the result of clinically meaningful social anxiety in several of the anxiety disorders, (c) significant differences among the anxiety disorders may have been hidden by heterogeneity among patients who receive the diagnosis of social phobia. and (d) the distribution of FNE scores in Turner et al.’s sample may have been unusually depressed

Working Alliance for Clients with Social Anxiety Disorder: Relationship with Session Helpfulness and Within-Session Habituation

It has been suggested that a strong working alliance encourages clients to take risks during therapy (Raue, Castonguay, & Goldfried, 1993). This encouragement may be important for clients who fear negative evaluations as they engage in risk-taking elements of therapy. This study examined the relationship between working alliance, session helpfulness, and measures of emotional processing in 18 clients undergoing cognitive behavior therapy (CBT) for social anxiety disorder. Results indicate a positive correlation between client-rated, but not observer-rated, working alliance and session helpfulness. Moderate levels of working alliance were associated with higher initial anxiety and deeper within-session habituation. Overall, a strong alliance was associated with clients engaging with the session and finding the session helpful. Implications for the use of CBT for social anxiety are discussed

Representations of the Self in Social Phobia: Vulnerability to Social Threat

A revised Stroop color-naming task was used to test hypotheses derived from Beck’s cognitive theory of anxiety disorders which proposes that social phobics are hypervigilant to social-evaluative threat cues. Color-naming latencies for social and physical threat words were compared to matched neutral words for both social phobics and individuals with panic disorder. As predicted, social phobics showed longer latencies for social threat words, and panickers had longer latencies for physical threat words. Latency for color-naming social threat words correlated with self-reported avoidance among social phobics. These results are consistent with Beck’s notion of self-schemata which facilitate the processing of threat cues. Methodological issues and clinical implications are discussed

Measuring Evaluation Fears in Adolescence: Psychometric validation of the Portuguese versions of the Fear of Positive Evaluation Scale and the Specific Fear of Negative Evaluation Scale

Modified measures of Fear of Negative Evaluation and Fear of Positive Evaluation were examined among Portuguese adolescents. These measures demonstrated replicable factor structure, internal consistency, and positive relationships with social anxiety and avoidance. Gender differences were found. Implications for evaluation and intervention are discussed

Cross section and analyzing power of pol{p}p -> pn pi+ near threshold

The cross section and analyzing power of the pol{p}p -> pn pi+ reaction near threshold are estimated in terms of data obtained from the pol{p}p -> d pi+ and pp -> pp pi0 reactions. A simple final state interaction theory is developed which depends weakly upon the form of the pion-production operator and includes some Coulomb corrections. Within the uncertainties of the model and the input data, the approach reproduces well the measured energy dependence of the total cross section and the proton analyzing power at a fixed pion c.m. angle of 90deg, from threshold to T_p = 330 MeV. The variation of the differential cross section with pion angle is also very encouraging.Comment: 20 pages, Latex including 4 eps figure

Ectopic Expression of E2F1 Stimulates β-Cell Proliferation and Function

OBJECTIVE-Generating functional beta-cells by inducing their proliferation may provide new perspectives for cell therapy in diabetes. Transcription factor E2F1 controls G(1)- to S-phase transition during the cycling of many cell types and is required for pancreatic beta-cell growth and function. However, the consequences of overexpression of E2F1 in beta-cells are unknown. RESEARCH DESIGN AND METHODS-The effects of E2F1 overexpression on beta-cell proliferation and function were analyzed in isolated rat beta-cells and in transgenic mice. RESULTS-Adenovirus AdE2F1-mediated overexpression of E2F1 increased the proliferation of isolated primary rat beta-cells 20-fold but also enhanced beta-cell death. Coinfection with adenovirus Ad Akt expressing a constitutively active form of Akt (protein kinase B) suppressed beta-cell death to control levels. At 48 h after infection, the total beta-cell number and insulin content were, respectively, 46 and 79% higher in AdE2F1+AdAkt-infected cultures compared with untreated. Conditional overexpression of E2F1 in mice resulted in a twofold increase of beta-cell proliferation and a 70% increase of pancreatic insulin content, but did not increase beta-cell mass. Glucose-challenged insulin release was increased, and the mice showed protection against toxin-induced diabetes. CONCLUSIONS-Overexpression of E2F1, either in vitro or in vivo, can stimulate beta-cell proliferation activity. In vivo E2F1 expression significantly increases the insulin content and function of adult beta-cells, making it a strategic target for therapeutic manipulation of beta-cell function. Diabetes 59:1435-1444, 201