35 research outputs found

    Methanotrophy, Methylotrophy, the Human Body and Disease

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    Methylotrophic Bacteria use one-carbon (C1) compounds as their carbon source. They have been known to be associated to the human body for almost 20 years as part of the normal flora and were identified as pathogens in the early 1990s in end-stage HIV patients and chemotherapy patients. In this chapter, I look at C1 compounds in the human body and exposure from the environment and then consider Methylobacterium spp. and Methylorubrum spp. in terms of infections, its role in breast and bowel cancers; Methylococcus capsulatus and its role in inflammatory bowel disease, and Brevibacterium casei and Hyphomicrobium sulfonivorans as part of the normal human flora. I also consider the abundance of methylotrophs from the Actinobacteria being identified in human studies and the potential bias of the ionic strength of culture media and the needs for future work. Within the scope of future work, I consider the need for the urgent assessment of the pathogenic, oncogenic, mutagenic and teratogenic potential of Methylobacterium spp. and Methylorubrum spp. and the need to handle them at higher containment levels until more data are available

    Porous cordierite-based ceramics processed by starch consolidation casting – Microstructure and high-temperature mechanical behavior

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    Porous cordierite-based ceramics with different microstructural features and mechanical behavior were formed by starch consolidation casting (SCC) using native potato and corn starches and sintered at 1275, 1300 and 1330 °C. The composition and microstructure of the ceramic materials were investigated via quantitative phase analysis using X-ray diffraction (with Rietveld refinement), the Archimedes method, mercury porosimetry, scanning electron microscopy and optical microscopy with stereology-based image analysis. The mechanical behavior of samples was evaluated by diametral compression tests at room temperature, 1000 and 1100 °C. The type of starch used and the sintering temperatures were the main factors determining the characteristics of the developed porous microstructures. Materials prepared with corn starch achieved the lowest porosity and the lowest values of mean chord length, mean pore distance and pore throat size. Because of these features, these materials thus presented, in general, higher values of apparent Young´s modulus, elastic limit and mechanical strength than those prepared with potato starch. Despite the presence of a silicate glassy phase, both porous materials, mainly those prepared with corn starch, still enhanced the basic mechanical properties at high temperature, in particular, the mechanical strength and the apparent Young´s modulus due to the special combination of the porous microstructure features.Fil: Sandoval, María Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Talou, Mariano H.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Tomba Martinez, Analía G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Camerucci, M. Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Gregorová, Eva. University of Chemistry and Technology; República ChecaFil: Pabst, Willi. University of Chemistry and Technology; República Chec

    Microwave sintering of cordierite precursor green bodies prepared by starch consolidation

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    This paper reports on a study of the microwave sintering behavior of green disks prepared by the starch consolidation forming method to produce cordierite-based porous materials. Green disks were formed by thermogelling the aqueous suspensions of talc, kaolin and alumina (29.6 vol.%) and potato starch (11.5 vol.%) at 75 and 85 ºC for 4 h, drying and calcining. They were characterized by bulk density and apparent porosity measurements, and SEM. Microwave sintering was carried out at 1300 and 1330 ºC for 15, 20 and 25 min, applying 50 ºC/min. For purposes of comparison, an analysis of green disks prepared and calcined in the same conditions and conventionally sintered (1330 ºC for 4 h) was also made. The materials were characterized by XRD, bulk density and apparent porosity measurements, and microstructurally analyzed SEM. The results were analyzed considering the behavior of starch in aqueous suspension at varying temperatures, and the experimental conditions of consolidation and sintering.Fil: Sandoval, María Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; ArgentinaFil: Talou, Mariano Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; ArgentinaFil: De Souto P. M.. Universidade Federal do Sao Carlos; BrasilFil: Kiminami, R. H. G. A.. Universidade Federal do Sao Carlos; BrasilFil: Camerucci, Maria Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; Argentin
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