84 research outputs found

    POLAR, an instrument to measure GRB polarization. Design and laboratory tests.

    Get PDF
    International audienceReliable polarization measurements of photons from Gamma Ray Bursts (GRB) would make the understanding of the GRB phenomenon progress enormously. POLAR is a concept for an instrument that would enable such a measurement. We report about performances predicted by of Monte-Carlo and on laboratory tests to validate some critical aspects of the desig

    Mechanisms generating long-range correlation in nucleotide composition of the Borrelia burgdorferi genome

    No full text
    Abstract We have analysed protein coding and intergenic sequences in the Borrelia burgdorferi (the Lyme disease bacterium) genome using di erent kinds of DNA walks. Genes occupying the leading strand of DNA have signiÿcantly di erent nucleotide composition from genes occupying the lagging strand. Nucleotide compositional bias of the two DNA strands re ects the aminoacid composition of proteins. 96% of genes coding for ribosomal proteins lie on the leading DNA strand, which suggests that the positions of these as well as other genes are non-random. In the B. burgdorferi genome, the asymmetry in intergenic DNA sequences is lower than the asymmetry in the third positions in codons. All these characters of the B. burgdorferi genome suggest that both replication-associated mutational pressure and recombination mechanisms have established the speciÿc structure of the genome and now any recombination leading to inversion of a gene in respect to the direction of replication is forbidden. This property of the genome allows us to assume that it is in a steady state, which enables us to ÿx some parameters for simulations of DNA evolution. c 1999 Elsevier Science B.V. All rights reserved. PACS: 87.14.G; 05.10-a Keywords: Long-range correlation; Replication; Transcription * Corresponding author. Fax: +48-71-3252151. E-mail addresses: [email protected] (S. Cebrat), [email protected] (M.R. Dudek) 0378-4371/99/$ -see front matter c 1999 Elsevier Science B.V. All rights reserved. PII: S 0 3 7 8 -4 3 7 1 ( 9 9 ) 0 0 3 4 5 -3 104 P. Mackiewicz et al. / Physica A 273 (1999) 103-11

    POLAR: a space borne GRB polarimeter

    Get PDF
    International audienceThe direction and the level of polarization of high energy photons emitted by astrophysics sources are valuable observables for the understanding of the corresponding emission mechanisms, source geometry and strength of magnetic fields at work. POLAR is a novel compact space-borne detector conceived for a precise measurement of hard X-ray polarization and optimized for the detection of Gamma-Ray Burst (GRB) photons in the energy range 50-500 keV. In POLAR, the GRB photons undergo Compton scattering in a target made out of 1600 plastic scintillator bars. The azimuthal distribution of the scattered photons inside the target provides the information on the GRB polarization. The target is divided into 5x5 units, each one consisting of 8x8 scintillator bars optically coupled with a multi-anode photomultiplier. POLAR, thanks to its large modulation factor (mu_100=40%), its large effective area (Aeff = 250 cm2), and its large field of view ( 1/3 of the sky) will be able to determine the degree and angle of polarization of a strong GRB with a minimum detectable polarization of less than 10% (3sigma). In this communication the present design and status of the POLAR project is presented. Expected results through deep Monte Carlo simulation studies as well as the recent results of laboratory measurements are detailed

    Observations of the Gamow-Teller resonance in the rare-earth nuclei above Gd 146 populated in β decay

    Get PDF
    13 págs.; 11 figs. ; 1 tab.The rare-earth region of the nuclear table around the quasi-doubly magic nucleus Gd146 is one of the very few places in which the Gamow-Teller (GT) resonance can be populated in β decay. The appropriate technique to study such a phenomenon is total absorption spectroscopy, thanks to which one can measure the B(GT) distribution in β-decay experiments even when it is very fragmented and lies at high excitation energy in the daughter nucleus. Results on the GT resonance measured in the β decay of the odd-Z, N=83 nuclei Tb148, Ho150, and Tm152 are presented in this work and compared with shell-model calculations. The tail of the resonance is clearly observed up to the limit imposed by the Q value. This observation is important in the context of the understanding of the >quenching> of the GT strength. ©2016 American Physical SocietyThe authors would like to thank the GSI accelerator crew and the MSEP group for their support. This work has been partially supported by the Spanish Ministry (Grants No. FPA2005-03993, No. FPA200806419-C02-01, No. FPA2011- 24553, No. FPA2012-32443, No. FPA2014-57196-C5, and No. FPA2014-52823-C2-1-P) and the Generalitat Valenciana (PROMETEOII/2014/019).Peer Reviewe

    Fine structure of the Gamow-Teller resonance revealed in the decay of Ho-150 2(-) isomer

    Get PDF
    The γ rays following the 72s 150Ho 2- Gamow-Teller β decay have been investigated with the CLUSTER CUBE setup, an array of six EUROBALL CLUSTER Ge detectors in close cubic geometry, providing a γ ray detection sensitivity of 2×10-5 per β-parent decay for γ-ray energies up to 5 MeV. The fine structure of the Gamow-Teller resonance at 4.4-MeV excitation in 150Dy has been studied. The resolved levels are compared with Shell Model predictions

    Mathematical modeling and comparison of protein size distribution in different plant, animal, fungal and microbial species reveals a negative correlation between protein size and protein number, thus providing insight into the evolution of proteomes

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>The sizes of proteins are relevant to their biochemical structure and for their biological function. The statistical distribution of protein lengths across a diverse set of taxa can provide hints about the evolution of proteomes.</p> <p>Results</p> <p>Using the full genomic sequences of over 1,302 prokaryotic and 140 eukaryotic species two datasets containing 1.2 and 6.1 million proteins were generated and analyzed statistically. The lengthwise distribution of proteins can be roughly described with a gamma type or log-normal model, depending on the species. However the shape parameter of the gamma model has not a fixed value of 2, as previously suggested, but varies between 1.5 and 3 in different species. A gamma model with unrestricted shape parameter described best the distributions in ~48% of the species, whereas the log-normal distribution described better the observed protein sizes in 42% of the species. The gamma restricted function and the sum of exponentials distribution had a better fitting in only ~5% of the species. Eukaryotic proteins have an average size of 472 aa, whereas bacterial (320 aa) and archaeal (283 aa) proteins are significantly smaller (33-40% on average). Average protein sizes in different phylogenetic groups were: Alveolata (628 aa), Amoebozoa (533 aa), Fornicata (543 aa), Placozoa (453 aa), Eumetazoa (486 aa), Fungi (487 aa), Stramenopila (486 aa), Viridiplantae (392 aa). Amino acid composition is biased according to protein size. Protein length correlated negatively with %C, %M, %K, %F, %R, %W, %Y and positively with %D, %E, %Q, %S and %T. Prokaryotic proteins had a different protein size bias for %E, %G, %K and %M as compared to eukaryotes.</p> <p>Conclusions</p> <p>Mathematical modeling of protein length empirical distributions can be used to asses the quality of small ORFs annotation in genomic releases (detection of too many false positive small ORFs). There is a negative correlation between average protein size and total number of proteins among eukaryotes but not in prokaryotes. The %GC content is positively correlated to total protein number and protein size in prokaryotes but not in eukaryotes. Small proteins have a different amino acid bias than larger proteins. Compared to prokaryotic species, the evolution of eukaryotic proteomes was characterized by increased protein number (massive gene duplication) and substantial changes of protein size (domain addition/subtraction).</p
    corecore