Embryonic Antigens and Growth of Murine Fibrosarcomata

The amount of embryonic antigens (EA) was estimated in 13 BALB/c fibrosarcomata by in vitro cell mediated cytotoxicity of anti-embryo spleen cells and by quantitative absorption of an anti-embryo antiserum. A direct relationship between amount of EA and tumour growing capacity was found. EA were detected also on fast dividing testicular cells. It is suggested that EA expression on tumour cells is related to a cell membrane function controlling mitosis rather than to a function specifically related to the neoplastic status. Tumour take of low doses of 2 EA-bearing sarcomata was found to be enhanced in anti-embryo immune BALB/c mice in comparison with that in normal and anti-fibroblast immune mice

Search for lepton flavour violation in the eμ continuum with the ATLAS detector in √s = 7 TeV pp collisions at the LHC

This paper presents a search for the t-channel exchange of an R-parity violating scalar top quark (t) in the e^± μ^∓ continuum using 2.1 fb^(−1) of data collected by the ATLAS detector in √s = 7 TeV pp collisions at the Large Hadron Collider. Data are found to be consistent with the expectation from the Standard Model backgrounds. Limits on R-parity-violating couplings at 95 % C.L. are calculated as a function of the scalar top mass (mt). The upper limits on the production cross section for pp → eμX, through the t-channel exchange of a scalar top quark, ranges from 170 fb for m_t=95 GeV to 30 fb for m_t=1000 GeV

A search for tt resonances with the ATLAS detector in 2.05 fb^(−1) of proton-proton collisions at √s =7 TeV

A search for top quark pair resonances in final states containing at least one electron or muon has been performed with the ATLAS experiment at the CERN Large Hadron Collider. The search uses a data sample corresponding to an integrated luminosity of 2.05 fb^(−1), which was recorded in 2011 at a proton-proton centre-of-mass energy of 7 TeV. No evidence for a resonance is found and limits are set on the production cross-section times branching ratio to tt for narrow and wide resonances. For narrow Z′ bosons, the observed 95 % Bayesian credibility level limits range from 9.3 pb to 0.95 pb for masses in the range of m_(Z′)=500 GeV to m_(Z′)=1300 GeV. The corresponding excluded mass region for a leptophobic topcolour Z′ boson (Kaluza-Klein gluon excitation in the Randall-Sundrum model) is m_(Z′)<880 GeV (m_(gKK)< 1130 GeV)

Inequality and elections in Italy, 1994–2018

The increase in income and wealth inequality in Italy is well documented, but less attention has been devoted to its association with social and political outcomes. This article investigates the association between inequality and several variables on socio-economic conditions with the evolution of Italian politics over the 1994–2018 period. Voting in Italy’s regions for the centre-left and centre-right coalitions—with a focus on the Lega—is examined in seven rounds of general elections, before and after the 2008 crisis, which emerges as a key divide in these relationships. The centre-left vote is higher in the regions with an increase in mean wealth and employment rates and shows a reversal after 2008 in the support of part time employees. The centre-right vote is associated with impoverished middle classes and an increase in disparities of Southern regions. The associations shown by Lega voting are distinct from those of other centre-right forces. While political and cultural factors are important to understand political changes, our findings show that a more unequal and distressed society is clearly associated with changes in electoral behaviour

On a probabilistic model for martensitic avalanches incorporating mechanical compatibility

Building on the work in [BCH15, CH18, TIVP17], in this article we propose and study a simple, geometrically constrained, probabilistic algorithm geared towards capturing some aspects of the nucleation in shape-memory alloys. As a main novelty with respect to the algorithms in [BCH15, CH18, TIVP17] we include mechanical compatibility. The mechanical compatibility here is guaranteed by using convex integration building blocks in the nucleation steps. We analytically investigate the algorithm’s convergence and the solutions’ regularity, viewing the latter as a measure for the fractality of the resulting microstructure. We complement our analysis with a numerical implemenation of the scheme and compare it to the numerical results in [BCH15, CH18, TIVP17]

Using instruments in the study of animate beings:Della Porta’s and Bacon’s experiments with plants

In this paper, I explain Francis Bacon's use of plants as philosophical instruments in the context of his Historia vitae et mortis. My main claim is that Bacon experimented with plants in order to obtain knowledge about the hidden processes of nature, knowledge that could be transferred to the human case and used for the prolongation of life. Bacon's experiments were based on Giambattista della Porta's reports from the Magia naturalis, but I show how a different metaphysics and research method made Bacon systematically rework, reconceptualise, and put to divergent uses the results of the same experimental reports

Measurement of dijet production with a veto on additional central jet activity in pp collisions at √s = 7TeV using the ATLAS detector

A measurement of jet activity in the rapidity interval bounded by a dijet system is presented. Events are vetoed if a jet with transverse momentum greater than 20 GeV is found between the two boundary jets. The fraction of dijet events that survive the jet veto is presented for boundary jets that are separated by up to six units of rapidity and with mean transverse momentum 50 < p_T < 500 GeV. The mean multiplicity of jets above the veto scale in the rapidity interval bounded by the dijet system is also presented as an alternative method for quantifying perturbative QCD emission. The data are compared to a next-to-leading order plus parton shower prediction from the powheg-box, an all-order resummation using the hej calculation and the pythia, herwig++ and alpgen event generators. The measurement was performed using pp collisions at √s=7 TeV using data recorded by the ATLAS detector in 2010

Concentration-Dependent Effects of N-3 Long-Chain Fatty Acids on Na,K-ATPase Activity in Human Endothelial Cells

N-3 eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) seem to prevent endothelial dysfunction, a crucial step in atherogenesis, by modulating the levels of vasoactive molecules and by influencing Na,K-ATPase activity of vascular myocytes. The activity of endothelial Na,K-ATPase controls the ionic homeostasis of the neighboring cells, as well as cell function. However, controversy exists with respect to the vascular protective effect of EPA and DHA. We argue that this dispute might be due to the use of different concentrations of EPA and DHA in different studies. Therefore, this study was designed to define an optimal concentration of EPA and DHA to investigate endothelial function. For this purpose, human endothelial cells were exposed for 24 h to different concentrations of DHA or EPA (0\u201320 \u3bcM) to study membrane fluidity, peroxidation potential and Na,K-ATPase activity. EPA and DHA were linearly incorporated and this incorporation was mirrored by the linear increase of unsaturation index, membrane fluidity, and peroxidation potential. Na,K-ATPase activity peaked at 3.75 \u3bcM of EPA and DHA and then gradually decreased. It is noteworthy that DHA effects were always more pronounced than EPA. Concluding, low concentrations of EPA and DHA minimize peroxidation sensitivity and optimize Na,K-ATPase activity