Comparison of Mediterranean sea level fields for the period 1961-2000 as given by a data reconstruction and a 3D model

Two Mediterranean sea level distributions spanning the last decades are examined. The first one is a reconstruction of sea level obtained by a reduced-space optimal interpolation applied to tide gauge and altimetry data. The second distribution is obtained from a 3D (baroclinic) regional circulation model. None of the two representations includes the mechanical atmospheric forcing. Results are presented for two different periods: 1993-2000 (for which altimetry data are available) and 1961-2000 (the longest period common to both distributions). The first period is examined as a test period for the model, since the reconstruction is very similar to altimetry observations. The modelled sea level is in fair agreement with the reconstruction in the Western Mediterranean and in the Aegean Sea (except in the early nineties), but in the Ionian Sea the model departs from observations. For the whole period 1961-2000 the main feature is a marked positive trend in the Ionian Sea (up to 1.8 mm yr- 1), observed both in the reconstruction and in the model. Also the distribution of positive trends in the Western Mediterranean (mean value of 1.1 mm yr- 1) and the smaller trends in the Aegean Sea (0.5 mm yr- 1) are similar in the reconstruction and in the model, despite the first implicitly accounts for sea level variations due to remote sources such as ice melting and the second does not. The interannual sea level variability associated with key regional events such as the Eastern Mediterranean Transient is apparently captured by the reconstruction but not by the model (at least in its present configuration). Hence, the reconstruction can be envisaged as a useful tool to validate further long-term numerical simulations in the region. © 2009 Elsevier B.V. All rights reserved.Peer Reviewe

Maternal urinary bisphenol a during pregnancy and maternal and neonatal thyroid function in the CHAMACOS study.

BackgroundBisphenol A (BPA) is widely used in the manufacture of polycarbonate plastic bottles, food and beverage can linings, thermal receipts, and dental sealants. Animal and human studies suggest that BPA may disrupt thyroid function. Although thyroid hormones play a determinant role in human growth and brain development, no studies have investigated relations between BPA exposure and thyroid function in pregnant women or neonates.ObjectiveOur goal was to evaluate whether exposure to BPA during pregnancy is related to thyroid hormone levels in pregnant women and neonates.MethodsWe measured BPA concentration in urine samples collected during the first and second half of pregnancy in 476 women participating in the CHAMACOS (Center for the Health Assessment of Mothers and Children of Salinas) study. We also measured free thyroxine (T4), total T4, and thyroid-stimulating hormone (TSH) in women during pregnancy, and TSH in neonates.ResultsAssociations between the average of the two BPA measurements and maternal thyroid hormone levels were not statistically significant. Of the two BPA measurements, only the one taken closest in time to the TH measurement was significantly associated with a reduction in total T4 (β = -0.13 µg/dL per log2 unit; 95% CI: -0.25, 0.00). The average of the maternal BPA concentrations was associated with reduced TSH in boys (-9.9% per log2 unit; 95% CI: -15.9%, -3.5%) but not in girls. Among boys, the relation was stronger when BPA was measured in the third trimester of pregnancy and decreased with time between BPA and TH measurements.ConclusionResults suggest that exposure to BPA during pregnancy is related to reduced total T4 in pregnant women and decreased TSH in male neonates. Findings may have implications for fetal and neonatal development

Urinary Metabolites of Di(2‐ethylhexyl) Phthalate Are Associated With Decreased Steroid Hormone Levels in Adult Men

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/96413/1/jandrol.108.006403.pd

Reliability of the spanish version of Questionnaire of Physical Activity PAQ-C

Objetivo. El objetivo de esta investigación ha sido valorar en niños españoles la fiabilidad del cuestionario de actividad física en niños mayores (PAQ-C). Método. Se utilizó como referencia la validación de la versión traducida al castellano del cuestionario de actividad física para adolescentes PAQ-A. En una muestra de 72 niños entre 8 y 14 años, se evaluó la fiabilidad test-retest del cuestionario PAQ-C en 3 mediciones, antes de la clase de educación física (M1), 2 horas después (M2) y al cabo de una semana (M3). La fiabilidad se calculó mediante el coeficiente de correlación intraclase (ICC) y la consistencia interna mediante el Coeficiente α de Cronbach. Resultados: Los valores obtenidos en la puntuación total del cuestionario reflejan un ICC superior a 0.73 en todas las comparaciones, con un intervalo de confianza al 95% que sigue indicando una fiabilidad buena o excelente. La consistencia interna mostró un coeficiente de α = 0,83Background: The aim of this study was to assess the reliability of the PAQ-C questionnaire in spanish older children (PAQ-C). Methods: A proof translation in Spanish of the physical activity questionnaire for teenager PAQ-A, was used as reference. Reliability of the test-retest questionnaire PAQ-C, was evaluated on 72 children aged between 8 and 14 years. Measurements were taken at three different stages: before the physical education class (M1), 2 hours after the lecture (M2) and one week later (M3). Reliability was calculated using the intraclass correlation coefficient (ICC) while the inner consistency by Cronbach's αcoefficient. Results: The results obtained in the overall score of the questionnaire reflect an intraclass coefficient (ICC) higher than 0,73 in every possible comparison giving a confidence interval of 95% which still indicates a good or very good reliability. The inner consistency showed a coefficient of α = 0,8

Long-term variations in global sea level extremes

Decadal to multidecadal variations in sea level extremes unrelated to mean sea level changes have been investigated using long tide gauge records distributed worldwide. A state space approach has been applied that provides robust solutions and uncertainties of the time evolving characteristics of extremes, allowing for data gaps and uneven sampling, both common features of historical sea level time series. Two different models have been formulated for the intensity and for the occurrence of extreme sea level events and have been applied independently to each tide gauge record. Our results reveal two key findings: first, the intensity and the frequency of occurrence of extreme sea levels unrelated to mean sea level vary coherently on decadal scales in most of the sites examined (63 out of 77) and, second, extreme sea level changes are regionally consistent, thus pointing toward a common large-scale forcing. This variability of extremes associated with climate drivers should be considered in the framework of climate change studies.M. Marcos acknowledges a “Ramon y Cajal” contract funded by the Spanish Ministry of Economy. This work was supported by the research project CLIMPACT (CGL2014-54246-C2-1-R) funded by the Spanish Ministry of EconomyPeer Reviewe

Personal Care Product Use Predicts Urinary Concentrations of Some Phthalate Monoesters

Phthalates are multifunctional chemicals used in a variety of applications, including personal care products. The present study explored the relationship between patterns of personal care product use and urinary levels of several phthalate metabolites. Subjects include 406 men who participated in an ongoing semen quality study at the Massachusetts General Hospital Andrology Laboratory between January 2000 and February 2003. A nurse-administered questionnaire was used to determine use of personal care products, including cologne, aftershave, lotions, hair products, and deodorants. Phthalate monoester concentrations were measured in a single spot urine sample by isotope dilution–high-performance liquid chromatography coupled to tandem mass spectrometry. Men who used cologne or aftershave within 48 hr before urine collection had higher median levels of monoethyl phthalate (MEP) (265 and 266 ng/mL, respectively) than those who did not use cologne or aftershave (108 and 133 ng/mL, respectively). For each additional type of product used, MEP increased 33% (95% confidence interval, 14–53%). The use of lotion was associated with lower urinary levels of monobutyl phthalate (MBP) (14.9 ng/mL), monobenzyl phthalate (MBzP) (6.1 ng/mL), and mono(2-ethylhexyl) phthalate (MEHP) (4.4 ng/mL) compared with men who did not use lotion (MBP, 16.8 ng/mL; MBzP, 8.6 ng/mL; MEHP, 7.2 ng/mL). The identification of personal care products as contributors to phthalate body burden is an important step in exposure characterization. Further work in this area is needed to identify other predictors of phthalate exposure

Personal Care Product Use Predicts Urinary Concentrations of Some Phthalate Monoesters

Phthalates are multifunctional chemicals used in a variety of applications, including personal care products. The present study explored the relationship between patterns of personal care product use and urinary levels of several phthalate metabolites. Subjects include 406 men who participated in an ongoing semen quality study at the Massachusetts General Hospital Andrology Laboratory between January 2000 and February 2003. A nurse-administered questionnaire was used to determine use of personal care products, including cologne, aftershave, lotions, hair products, and deodorants. Phthalate monoester concentrations were measured in a single spot urine sample by isotope dilution–high-performance liquid chromatography coupled to tandem mass spectrometry. Men who used cologne or aftershave within 48 hr before urine collection had higher median levels of monoethyl phthalate (MEP) (265 and 266 ng/mL, respectively) than those who did not use cologne or aftershave (108 and 133 ng/mL, respectively). For each additional type of product used, MEP increased 33% (95% confidence interval, 14–53%). The use of lotion was associated with lower urinary levels of monobutyl phthalate (MBP) (14.9 ng/mL), monobenzyl phthalate (MBzP) (6.1 ng/mL), and mono(2-ethylhexyl) phthalate (MEHP) (4.4 ng/mL) compared with men who did not use lotion (MBP, 16.8 ng/mL; MBzP, 8.6 ng/mL; MEHP, 7.2 ng/mL). The identification of personal care products as contributors to phthalate body burden is an important step in exposure characterization. Further work in this area is needed to identify other predictors of phthalate exposure

Long-term variations in global sea level extremes

Decadal to multidecadal variations in sea level extremes unrelated to mean sea level changes have been investigated using long tide gauge records distributed worldwide. A state space approach has been applied that provides robust solutions and uncertainties of the time evolving characteristics of extremes, allowing for data gaps and uneven sampling, both common features of historical sea level time series. Two different models have been formulated for the intensity and for the occurrence of extreme sea level events and have been applied independently to each tide gauge record. Our results reveal two key findings: first, the intensity and the frequency of occurrence of extreme sea levels unrelated to mean sea level vary coherently on decadal scales in most of the sites examined (63 out of 77) and, second, extreme sea level changes are regionally consistent, thus pointing toward a common large-scale forcing. This variability of extremes associated with climate drivers should be considered in the framework of climate change studies