Security of the Medical Media Using an Hybrid and Multiple Watermark Technique

International audienceThis paper proposes a new approach of multiple and hybrid watermark using two linked fields of insertion. This approach associates two different series of marks: one is sturdy guaranteeing the supervision of diffused media though the network and testifying to the identity of the owner of the medical image; the other series of marks, which is frail, insuring the integrity, the trace and the archives of medical diagnoses. In fact, this approach allows to benefit from the advantages of different insertion spaces (spatial and frequency field) and kind of two different fields of watermark. In the spatial field, the diagnosis of the doctor (frail marks) is inserted guaranteeing its records and its trace. In the frequency, the sturdy mark is inserted allowing to ensure the automatic control of the media through the network and testifying to the proprietor of the medical image

Use of Multi-Watermarking Schema to Maintain Awareness in a Teleneurology Diagnosis Platform

International audienceFollowing the tremendous evolution of transferring images through the Internet, it isnecessary to ensure security during this act and mainly for medical images.The application of multiple watermarking technique represents a solution to preserve the security of this data, on the one hand, and the traceability of medical diagnoses made by doctors, on the other hand. This falls under remote collaborative work.This technique is applied in the TeNeCi (Collaborative tele-neurology) platform. Thisproject allows practitioners to distribute the analyses of the medical image. In fact, we used the multiple watermarking technique in a wavelet field. The theory underlying this technique is to hide information in the medical image and to ensure at the same time its imperceptibility. The diagnosis made by the practitioner is the inserted data in theimage. The fundamental challenge of this paper is how to hide the total diagnoses of each practitioner in the image ensuring a good quality of the imageat the same time

New Watermarking Scheme for Security and Transmission of Medical Images for PocketNeuro Project

We describe a new Watermarking system of medical information security and terminal mobile phone adaptation for PocketNeuro project. The later term refers to a Project created for the service of neurological diseases. It consists of transmitting information about patients \"Desk of Patients\" to a doctor\'s mobile phone when he is visiting or examining his patient. This system is capable of embedding medical information inside diagnostic images for security purposes. Our system applies JPEG Compression to Watermarked images to adapt them to the doctor\'s mobile phone. Experiments performed on a database of 30-256x256 pixel-sized neuronal images show that our Watermarking scheme for image security is robust against JPEG Compression. For the purpose of increasing the image Watermarking robustness against attacks for an image transmission and to perform a large data payload, we encode with Turbo-Code image-embedded bits information. Fidelity is improved by incorporation of the Relative Peak Signal-to-Noise Ratio (RPSNR) as a perceptual metric to measure image degradation

A B-Spline-Based Generative Adversarial Network Model for Fast Interactive Airfoil Aerodynamic Optimization

Airfoil aerodynamic optimization is of great importance in aircraft design; however, it relies on high-fidelity physics-based models that are computationally expensive to evaluate. In this work, we provide a methodology to reduce the computational cost for airfoil aerodynamic optimization. Firstly, we develop a B-spline based generative adversarial networks (BSplineGAN) parameterization method to automatically infer design space with sufficient shape variability. Secondly, we construct multi-layer neural network (MNN) surrogates for fast predictions on aerodynamic drag, lift, and pitching moment coefficients. The BSplineGAN has a relative error lower than 1% when fitting to UIUC database. Verification of MNN surrogates shows the root means square errors (RMSE) of all aerodynamic coefficients are within the range of 20%–40% standard deviation of testing points. Both normalized RMSE and relative errors are controlled within 1%. The proposed methodology is then demonstrated on an airfoil aerodynamic optimization. We also verified the baseline and optimized designs using a high-fidelity computational fluid dynamic solver. The proposed framework has the potential to enable web-based fast interactive airfoil aerodynamic optimization

Biochemical status, oxidative and antioxidant responses after 3-month specific training in elite karate athletes

Aim To investigate the effects of 3-month-long specific training program on biochemical status, oxidative and antioxidant responses in elite karatekas. Methods Twenty male karatekas [BMI: 21.9 ± 2.4 (kg/m2)] participated in this study. They performed a 3-month specific training to prepare for an international competition. We measured selected biochemical parameters, the oxidative and antioxidant responses before (T0) and after 3 months of intense karate training (T1). Results We found significant increases in catalase activity (26.3% ± 21.3%, p  Conclusions The specific training program improves the prooxidant–antioxidant balance of elite karate athletes. It could be recommended for athletes having similar physical fitness level

Uptake of oxLDL and IL-10 production by macrophages requires PAFR and CD36 recruitment into the same lipid rafts

Macrophage interaction with oxidized low-density lipoprotein (oxLDL) leads to its differentiation into foam cells and cytokine production, contributing to atherosclerosis development. In a previous study, we showed that CD36 and the receptor for platelet-activating factor (PAFR) are required for oxLDL to activate gene transcription for cytokines and CD36. Here, we investigated the localization and physical interaction of CD36 and PAFR in macrophages stimulated with oxLDL. We found that blocking CD36 or PAFR decreases oxLDL uptake and IL-10 production. OxLDL induces IL-10 mRNA expression only in HEK293T expressing both receptors (PAFR and CD36). OxLDL does not induce IL-12 production. The lipid rafts disruption by treatment with βCD reduces the oxLDL uptake and IL-10 production. OxLDL induces co-immunoprecipitation of PAFR and CD36 with the constitutive raft protein flotillin-1, and colocalization with the lipid raft-marker GM1-ganglioside. Finally, we found colocalization of PAFR and CD36 in macrophages from human atherosclerotic plaques. Our results show that oxLDL induces the recruitment of PAFR and CD36 into the same lipid rafts, which is important for oxLDL uptake and IL-10 production. This study provided new insights into how oxLDL interact with macrophages and contributing to atherosclerosis development

Polar extracts from (Tunisian) Acacia salicina Lindl. Study of the antimicrobial and antigenotoxic activities

<p>Abstract</p> <p>Background</p> <p>Methanolic, aqueous and Total Oligomer Flavonoids (TOF)-enriched extracts obtained from the leaves of <it>Acacia salicina </it>'Lindl.' were investigated for antibacterial, antimutagenic and antioxidant activities.</p> <p>Methods</p> <p>The antimicrobial activity was tested on the Gram positive and Gram negative reference bacterial strains. The Mutagenic and antimutagenic activities against direct acting mutagens, methylmethane sulfonate (MMS) and 4-nitro-o-phenylenediamine (NOPD), and indirect acting mutagens, 2-aminoanthracene (2-AA) and benzo[a]pyrene (B(a)P) were performed with <it>S. typhimurium </it>TA102 and TA98 assay systems. In addition, the enzymatic and nonenzymatic methods were employed to evaluate the anti-oxidative effects of the tested extracts.</p> <p>Results</p> <p>A significant effect against the Gram positive and Gram negative reference bacterial strains was observed with all the extracts. The mutagenic and antimutagenic studies revealed that all the extracts decreased the mutagenicity induced by B(a)P (7.5 μg/plate), 2-AA (5 μg/plate), MMS (1.3 mg/plate) and NOPD (10 μg/plate). Likewise, all the extracts showed an important free radical scavenging activity towards the superoxide anion generated by the xanthine/xanthine oxidase assay system, as well as high Trolox Equivalent Antioxidant Capacity (TEAC), against the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS)⁺• radical. TOF-enriched extract exhibited the highest protective effect against free radicals, direct acting-mutagen and metabolically activated S9-dependent mutagens.</p> <p>Conclusions</p> <p>The present study indicates that the extracts from <it>A. salicina </it>leaves are a significant source of compounds with the antimutagenic and antioxidant activities, and this may be useful for developing potential chemopreventive substances.</p

Applications of Polynomial Chaos-Based Cokriging to Aerodynamic Design Optimization Benchmark Problems

In this work, the polynomial chaos-based Cokriging (PC-Cokriging) is applied to a benchmark aerodynamic design optimization problem. The aim is to perform fast design optimization using this multifidelity metamodel. Multifidelity metamodels use information at multiple levels of fidelity to make accurate and fast predictions. Higher amount of lower fidelity data can provide important information on the trends to a limited amount of high-fidelity (HF) data. The PC-Cokriging metamodel is a multivariate version of the polynomial chaos-based Kriging (PC-Kriging) metamodel and its construction is similar to Cokriging. It combines the advantages of the interpolation-based Kriging metamodel and the regression-based polynomial chaos expansions (PCE). In the work the PC-Cokriging model is compared to other metamodels namely PCE, Kriging, PC-Kriging and Cokriging. These metamodel are first compared in terms of global accuracy, measured by root mean squared error (RMSE) and normalized RMSE (NRMSE) for different sample sets, each with an increasing number of HF samples. These metamodels are then used to find the optimum. Once the optimum design is found computational fluid dynamics (CFD) simulations are rerun and the results are compared to each other. In this study a drag reduction of 73.1 counts was achieved. The multifidelity metamodels required 19 HF samples along with 1,055 low-fidelity to converge to the optimum drag value of 129 counts, while the single fidelity models required 155 HF samples to do the same

Isotope geochemistry of Mississippi Valley Type strataboundF-Ba-(Pb-Zn) ores of Hammam Zriba (Province of Zaghouan, NETunisia).

Peer reviewed journal article. Geology, 2017.Abstract available in PDF file