A study of the participating women in Lake Alau's fishery

The article discusses the increasing participation of women in artisanal fishery in Nigeria. The concept of involvement of women in poverty alleviation, food security and social development activities should have high priority and should put women on the research agenda as one of the means of bridging the gap in knowledge regarding their status and contribution in rural development in Nigeri

Effect of some free radicals on superoxide dismutase and carboxypeptidase - A review

Free radicals are species with unpaired electron in their outermost shell. Most free radicals come from oxygen or nitrogen atoms. Radical species such as superoxide radical, hydroxyl radicals and hydrated electron are called the primary radicals of water radiolysis and can be produced by irradiating water molecule. Inorganic radicals on the other hand are formed by irradiating aqueous solution of enzyme containing sodium or potassium salt of the radical to be produced. Superoxide dismutase, an important antioxidant enzyme can be inactivated by hydrogen peroxide at His-118 of the active site of the enzyme, while hydrated electron was found to be completely ineffective as inactivating specie. Hydrated electron was also found to be completely ineffective in the inactivation of carboxypeptidase, while there appears to be some relative efficiency with hydrogen atom.Keywords: hydroxyl radical (.OH); hydrogen atom (H.); hydrated electron (e-aq); superoxide dismutase SOD; Superoxide radical (O2.-

INTESTINAL HELMINTHIASIS AMONG CHILDREN AND ADULTS IN SOME HOSPITALS IN KANO METROPOLIS

Infection with parasitic helminthes is often recognized as one of the important public health problems in tropical Africa. The majority of this infection occurs in resource-limited settings like Sub-Saharan Africa including Nigeria. The aim of this study was to determine the prevalence of intestinal helminthes among children and adults in some hospitals in Kano metropolis. The study involved a cross-sectional survey of 134 stool samples where 84 were collected from children and 50 from adults. The samples were examined usingdirect wet mount and formol-ether concentration technique. The overall prevalence of intestinal helminth infection observed was 11.2%. In the study, three different parasites were identified. These include Ascaris lumbricoides, Trichuristrichura and Hookworm. In terms of isolation rate, Hookworm was the commonest intestinal helminth observed in children 5 (50%) while Ascarislumbricoides was the most isolated 3 (60%) in adults

Screening for Antibacterial Activity of Andrographis paniculata Used in Malaysian Folkloric Medicine: A Possible Alternative for the Treatment of Skin Infections

In this study non-polar (dichloromethane) and polar (MeOH & aqueous) extracts of A. paniculata (whole plant) were evaluated for in vitro antibacterial activity against 12 skin disease causing bacterial strains (7 gram positive strains; Staphylococcus saprophyticus, Staphylococcus epidermis, Staphylococcus aureus, Streptococcus pyogenes, Bacillus anthracis, Micrococcus luteus, Enterococcus faecalis) and 5 gram negative strains; Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, Neisseria meningitis, Pseudomonas aeruginosa ) using the disc diffusion method at three concentrations; 1000, 500, and 250 μg/disc respectively in order to ascertain its folkloric claim to treat skin infections. The extracts showed significant antibacterial activities against both the Gram-positive and Gram-negative bacterial strains tested. Highest significant antibacterial activity was exerted by the MeOH extract against E. faecalis at 1000 μg/disc (24.00 ± 0.00 mm) and the least activity by the DCM extract against N. meningitis at 250 μg/disc (6.00 ± 0.00mm). The minimum inhibitory concentration ranged between 150 μg /mL and 300 μg /mL depending on microorganism and various extracts. Presence of phytochemicals such as terpenoids, tannins, flavonoids, saponins, alkaloids, amino acids and steroids were observed. These results candidly suggest the presence of promising antibacterial substances in the polar as well as non-polar extracts which could be potential phytomedicine for the treatment of skin infections caused by pathogenic bacterial strains. These findings explicitly support its traditional claims and form a strong basis for further efforts to explore A. paniculata’s antibacterial potential to treat skin frailties efficaciously. Our results confer the utility of this plant extracts in developing a novel broad spectrum antimicrobial agent

DETOXIFICATION ENZYMES ACTIVITIES IN DDT AND BENDIOCARB RESISTANT AND SUCEPTIBLE MALARIAL VECTOR (Anopheles gambae) BREED IN AUYO RESIDENTIAL AND IRRIGATION SITES NORTHWEST NIGERIA

Evaluating levels of detoxifying enzymes is informative to governmental, nongovernmental organization and insecticides producing industries. In this work DDT and bendiocarb resistance status of Anopheles gambae breeds in Auyo (May – September, 2014) was studied. Larvae collected from residential sites (AR) and rice Irrigation sites (AI) of Auyo town in Auyo LGA Jigawa State Nigeria reared to adult was studied by WHO adult bioassay. Standard methods were adapted to determine the specific activities of insecticides detoxifying enzymes; glutathione s transferase (GST), esterase and monooxygenase in the insecticides resistant (r) and susceptible (s) vectors. In addition those tested with bendiocarb were analyzed for acetylcholinesterase activities. The finding of the study established high resistance status of the malarial vectors to DDT in both sites, low resistance status to bendiocarb in residential site and possible resistance to bendiocarb in irrigation site according to WHO interpretation. Significant (P<0.05) elevation in the activity of esterase and GST were seen in DDT resistant strain of residential site compared to susceptible (s). Significantly higher (P<0.05) specific activity of monooxygenase and acetyl cholinesterase was observed in bendiocarb resistant strain of both residential and irrigation sites, except for acetyl cholinesterase of irrigation site. Elevated activity of was observed in bendiocarb resistant strain of residential site. The finding of the study could be associated with indiscriminate use of insecticides in residential site against malarial vector and other flying insect and agrochemicals in the irrigation site. Base on this finding it may be concluded that conferring resistance to malarial vector is not restricted to agricultural area alone. Therefore challenge to researchers and chemical industries in fight against malarial should be redirected to producing specific irreversible and/or reversible inhibitors to these insecticides detoxifying enzymes

Effect of Administration of Aqueous Suspension of Ricinus communis Seeds on Serum Estrogen and Progesterone in Female Albino Rats

In this study, twenty seven (27) female albino rats were used in the determination of contraceptive effect of oral administration of aqueous suspension of Ricinus communis seed. Estrogen and progesterone levels of these rats were analysed using electrochemiluminescent method. The result revealed estrogenic property of the aqueous suspension of R. communis seed, which is partly attributed to the anticonceptive effect of the seeds. The estrogenic activity was high with 107×10-2mg/kg dose administered after 48hours and 7 days respectively, indicating some degree of dose-dependency. In addition, alteration of estrogen/progesterone balance as indicated by this study may be responsible for the contraceptive effect of aqueous suspension of R. communis seed. Keywords: Contraceptive effect, Estrogen, Estrogenic activity, Progesterone, Ricinus communi

Isolation, Characterization and Heavy Metals Tolerance Indices of Indigenous Fungal Flora from a Tannery located at Challawa Industrial Estate of Kano State, Nigeria

Seven fungal species (Aspergillus niger, Aspergillus versicolor, Aspergillus flavus, Aspergillus fumigatus, Rhizomucor pusillus, Trichophyton equinum and Rhizopus oryzae) were isolated from the tannery effluent collected at a tannery industry located at Challawa industrial estate of Kano State, Nigeria. Aspergillus niger had the highest percentage occurrence frequency of 36% (31) while Trichophyton equinum had the least percentage occurrence frequency of 4% (5). Consequently, Aspergillus niger recorded the highest mean tolerance indices of 1.175, 0.830, 0.580, 0.780 and 0.630 while Rhizomucor pusillus had the least of the tolerance indices of 0.675, 0.375, 0.346, 0.450 and 0.255 for chromium, cadmium, manganese and lead respectively. Accordingly, furthermore the minimum inhibitory concentration (MIC) and biomass yield of the seven tested fungi isolates cultured in the presence of the five heavy metals used in this study showed different level of growth pattern. Hence the high resistant potentials and tolerance to the selected heavy metals exhibited by the fungal species isolated in this study is an indication that indigenous fungal floral isolated from tannery effluent if properly harnessed may offer a feasible solution to the serious environmental pollution problems associated with the presence of heavy metals in tannery effluent

Signet ring lymphoma: The import of immunohistochemistry in resolving diagnostic dilemnas

Signet ring cell lymphomas are a rare subtype of non Hodgkin lymphoma characterised by malignant lymphoid cells with cytoplasmic inclusions that displace the nucleus and imparts a “signet ring” appearance.This poses a diagnostic challenge as it can be mistaken for an adenocarcinoma or any other epithelial malignancy.A 54yr old male presented with a 6month history of generalised lymphadenopathy. Examination of excision biopsy of the lymph nodes show effacement of architecture by sheets neoplastic cells with abundant cytoplasm distended by eosinophilic amorphous substances. Immunohistochemistry with a panel of three monoclonal antibodies [LCA, CD20, and CD3] confirmed these cells to be of lymphoid origin.Keywords: Non Hodgkin Lymphoma;Signet Ring,Immunohistochemistr

Assessment of Automobiles and Pedestrians Control Techniques Within Markets in Kaduna State, Nigeria

The Assessment of automobile and pedestrian control techniques within the market environment cannot be overemphasized as it is one of the most important ways in curtailing poor market environment in terms of traffic congestion. Automobile and pedestrian congestion is a situation that arises when the road networks are incapable of accommodating the traffic generated. Automobile and pedestrians control techniques in market refers to regulation, adoption, or maintenance of automobile and pedestrian functions or feature either by design or new construction within the market. The sustainable design encompasses standard layout, adequate parking, standard road network system, provision of signs and markings, proper zoning etc. This research aimed at assessing pedestrian and automobile control technique adopted within markets in Kaduna with the view of designing a more improved circulation pattern and sustainable markets in terms of automobile and pedestrian control within the study area. With this regard, an observation method of research was adopted. The daily markets were randomly selected out of the numerous markets within Kaduna metropolis and its environs. The result shows that the proper automobiles and pedestrians control techniques was not properly observed or  adopted in over 90% of the market. The study further revealed that the selected markets within Kaduna share similar features and characteristics. Therefore to curtail these, recommendations were made on various practical methods for integration/adoption in market design so as to archive an effective automobile control within the markets in Kaduna metropolis. Keywords: Automobiles, Control Techniques, Market Congestion, Pedestria