Strategie radzenia sobie z bólem neuropatycznym oraz wpływ dolegliwości bólowych na stan funkcjonalny chorych

Introduction. Determining the strategies, which patients implement in order to fight the pain and the extent, to which they are able to control symptoms can greatly facilitate the selection of appropriate treatment.Aim. The study aimed at assessing strategies to cope with pain by patients suffering from neuropathic pain.Material and Methods. The study group consisted of 60 patients of the Pain Management Unit aged of 25–80 years suffering from neuropathic pain. The study was performed with the use of Coping Strategies Questionnaire (CSQ), Visual Analogue Scale (VAS) as well as a survey of own design.Results. The average intensity of pain in the study group was 7.88 in VAS (±1.64). The most widely used strategy for dealing with pain in the study group was Praying (av. 3.3±1.1), whereas on the second place was Catastrophizing (av. 3.1±1.6). The patients over the age of 60 are significantly more likely to apply those strategies than younger patients. The other strategies were applied above all by the patients below 60.Conclusions. The most often applied strategies in the study group was Praying and Catastrophizing. The choice of strategies for coping with pain varied depending on age, to lesser extend it was conditioned the gender. (JNNN 2016;5(1):10–15)Wstęp. Poznanie strategii, jakie podejmuje pacjent w walce z bólem oraz stopnia, w jakim jest w stanie opanować dolegliwości może znacznie ułatwić dobór odpowiedniego leczenia.Cel. Celem pracy była ocena strategii radzenia sobie z bólem przez pacjentów cierpiących z powodu bólu neuropatycznego.Materiał i metody. Badaniem objęto 60 pacjentów Poradni Leczenia Bólu w przedziale wiekowym 25–80 lat, cierpiących z powodu bólu neuropatycznego. Posłużono się kwestionariuszem „Strategii radzenia sobie z bólem” (ang. Coping Strategies Questionnaire, CSQ), wzrokowo-analogową skalą oceny bólu (ang. Visual Analogue Scale, VAS) oraz kwestionariuszem ankiety własnej konstrukcji.Wyniki. Średnie natężenie dolegliwości bólowych w badanej grupie wynosiło 7,88 pkt w skali VAS (±1,64 pkt). Najpowszechniej stosowaną strategią radzenia sobie z bólem w badanej grupie była modlitwa (śr. 3,3±1,1), a na drugim miejscu katastrofizowanie (śr. 3,1±1,6). Pacjenci powyżej 60 roku życia istotnie częściej niż młodsi chorzy wybierali powyższe strategie. Wybór pozostałych strategii był domeną chorych poniżej 60 roku życia.Wnioski. Najczęściej stosowanymi strategiami w badanej grupie były modlitwa i katastrofizowanie. Dobór strategii radzenia sobie z bólem był zróżnicowany w zależności od wieku, w mniejszym stopniu zależał od płci badanych. (PNN 2016;5(1):10–15

Ocena jakości komunikacji przez osoby z afazją Broki

Language is a means of transferring information, and the ability to communicate has a fundamental meaning to every human being. Loss of the ability or deterioration of communication in people with Broca’s aphasia affects their psychosocial functioning. The aim of this research was to obtain information on the subjective evaluation of the quality of communication of people with this type of aphasia. A group of 22 patients with Broca’s aphasia caused by ischemic stroke was included in the study. A diagnostic survey method was used, along with own study questionnaire research tool (Communication Quality Assessment Questionnaire). Socio-demographic data of the patients was recorded. The results of the study showed that almost all patients with Broca’s aphasia negatively assess their own communication capabilities and also feel they are negatively perceived by their surroundings because of their communication difficulties. Dissatisfaction with the quality of the communication prevents the subjects from maintaining satisfactory contacts with other people.Język jest środkiem służącym do przekazywania informacji, a możliwość porozumiewania się ma podstawowe znaczenie dla każdego człowieka. Utrata tej możliwości lub zaburzenia porozumiewania się osób z afazją Broki wywierają wpływ na ich funkcjonowanie psychospołeczne. Celem przeprowadzonego badania było uzyskanie informacji na temat subiektywnej oceny jakości komunikacji osób z tym typem afazji. Badaniem objęto grupę 22 pacjentów z afazją Broki po udarze niedokrwiennym mózgu. Posłużono się metodą sondażu diagnostycznego, a narzędziem badawczym był kwestionariusz własnego opracowania – Kwestionariusz oceny jakości komunikacji. Udokumentowano dane społeczno-demograficzne pa-cjentów. Wyniki badania pokazały, że niemal wszyscy chorzy z afazją Broki dokonali negatywnej oceny swoich możliwości komunikacyjnych, a także czuli się negatywnie oceniani przez otoczenie z powodu trudności w porozumiewaniu się. Nie-zadowolenie z jakości komunikacji uniemożliwia badanym utrzymywanie satysfakcjonujących kontaktów z innymi ludźmi

Psychoza jako ekstensywny wymiar ideologii

In this short dissertation, the author makes an attempt to answer the question of the usefulness of psychoanalysis in the field of a political practice, beginning with Freudian analysis of group psychology and Lacanian concept of paranoia. The central point, around which interpretation revolves, is the moment of the flag collapse described in Henryk Sienkiewicz’s novel. It is possible to reveal what is called psychotic crisis and the nature of social order based on the concept of empty meaning, thanks to the precision of the plot. In this context, psychoanalysis eliminates its instrumental use in all possible political practices. Since, it’s impossible to support a project which, as a project itself, is a source of all problems

Psychoza jako ekstensywny wymiar ideologii

Pora postawić pytanie o użyteczność psychoanalizy w polu polityczności i polityki zgodnie ze znaczeniem, jakie tym terminom nadaje Chantal Mouffe; polityczności rozumianej jako „wymiar antagonizmu leżący u podstaw każdego ludzkiego społeczeństwa oraz polityki definiowanej przez zestaw praktyk i instytucji, które w obliczu wprowadzonego przez polityczność konfliktu tworzą porządek umożliwiający ludzkie współistnienie

Eponyms in Dance Terminology as an Object of Translation

This paper raises both the issue of eponyms emerging in dance terminology and problems concerning their translation. In Section 1, a short introduction to the topic is presented. Section 2 covers theoretical background crucial to understand the topic, defining the notion of an eponym vital to the paper, as well as the term of sociolect in terms of dance community. Moving on to the methodology of this research, Section 3 contains the corpus of 56 Polish eponyms in dance terminology, gathered mostly from books such as Kopaliński’s “Słownik eponimów, czyli wyrazów odimiennych” (1996), his “Słownik wyrazów obcych i zwrotów obcojęzycznych” (2003), Chodkowski’s “Encyklopedia muzyki” (1995), Dąbrowska’s “W kręgu polskich tańców ludowych” (1979) and during various lectures conducted by numerous dance teachers, along with English translations of the units. Then, a quantitative and qualitative analysis of the corpus is discussed. Finally, in Section 4, conclusion of the research is presented to show the complexity of the issue of eponyms and problems that may occur in their translation.Chambers, Jack, Trudgill, Peter (1998) Dialectology. New York: Cambridge University Press. Chodkowski, Andrzej (1995) Encyklopedia muzyki. Warszawa: Wydawnictwo PWN. Collins English Dictionary – Complete & Unabridged 10th Edition 2009: “Eponym”. Retrieved from: http://dictionary.reference.com/browse/eponym. Date: 28th August 2020 Craine, Debra, Mackrell, Judith (2010) The Oxford Dictionary of Dance. Oxford: Oxford University Press. Dąbrowska, Grażyna (1979) W kręgu polskich tańców ludowych. Warszawa: Ludowa Spółdzielnia Wydawnicza Grabias, Stanisław (1997) Język w zachowaniach społecznych. Lublin: Wydawnictwo Uniwersytetu Marii Curie Skłodowskiej. Grabias, Stanisław (2001) “Środowiskowe i zawodowe odmiany języka – socjolekty”, [In:] [Współczesny język polski, 223-240] Bartmiński, J. (ed.), Lublin: UMCS. Haigh, Chris (2009) The Fiddle Handbook. London: Backbeat Books. Khokhlova, Irina Nickolaevna (2017) “Contact variantology: problems of national language variety terminology” [In:] [Saudi Journal of Humanities and Social Sciences, 2017; 2(1):15-18]. Retrieved from: http://scholarsmepub.com/wp-content/uploads/2017/02/SJHSS-2115-18.pdf. Date: 28th August 2020. Kopaliński, Władysław (2003) Słownik wyrazów obcych i zwrotów obcojęzycznych z almanachem. Warszawa: Wydawnictwo PWN. Kopaliński, Władysław (1996) Słownik eponimów, czyli wyrazów odimiennych. Warszawa: Wydawnictwo PWN. Lewandowski, Marcin (2008) “The Language of Soccer – a Sociolect or a Register?” [In:] [Język, Komunikacja, Informacja, 3/2008: 21-32] P. Nowak, P. Nowakowski (eds.). Retrieved from: https://repozytorium.amu.edu.pl/bitstream/10593/4562/1/02- Lewandowski.pdf. Date: 28th August 2020. McArthur, Thomas (1996) The Oxford Companion to the English Language. Oxford: Oxford University Press Murrmann, Julia (2014) Profesjolekt branży turystycznej, czyli o specyficznych cechach zawodowego języka turystyki” [In:] [Rozprawy Naukowe Akademii Wychowania Fizycznego we Wrocławiu 47, 47-57]. Retrieved from: http://cejsh.icm.edu.pl/cejsh/element/bwmeta1.element.desklight-b05414f5-c42f-49b0-b7b0-810e26136e00. Date: 28th August 2020. Newman, Albert (1914) Dances of to-day, Philadelphia: The Penn Publishing Co. Popescu, Floriana, Sorcaru, Daniela (2008) Eponyms: an instance of linguistic interculturality. Retrieved from: https://www.yumpu.com/en/document/view/9502218/culture-subculture-and-counterculture-facultatea-de-litere/167. Date: 28th August 2020. Rudnicka, Ewa (2004) “Eponimical lexical items as the object of translation”. [In:] [Bісник Сумского державного університету, серія “Філологічні науки” 4(63) 154-161] Retrieved from: http://www.vuzlib.com.ua/articles/book/25635- Eponymical_lexical_items_as_th/1.html. Date: 28th August 2020. Sadowski, Mirosław (2013) „Eponimy jako sposób wzbogacania leksyki” [In:] [„Acta Erasmiana”]. Retrieved from: https://www.academia.edu/15578944/Eponimy_jako_spos%C3%B3b_wzbogacania_leksyki_Eponyms_as_a_mean_of_enriching_vocabulary_. Date: 28th August 2020. Trudgill, Peter (2003) A Glossary of Sociolinguistics. Edinburgh: Edinburgh University Press Wilkoń, Aleksander (2000) Typologia odmian językowych współczesnej polszczyzny. Katowice: Wydawnictwo Uniwersytetu Śląskiego

Antibody-based antiangiogenic and antilymphangiogenic therapies to prevent tumor growth and progression

Blood and lymphatic vessel formation is an indispensable factor for cancer progression and metastasis. Therefore, various strategies designed to block angiogenesis and lymphangiogenesis are being investigated in the hope to arrest and reverse tumor development. Monoclonal antibodies, owing to their unequalled diversity and specificity, might be applied to selectively inhibit the pathways that cancer cells utilize to build up a network of blood vessels and lymphatics. Among the possible targets of antibody-based therapies are proangiogenic and prolymphangiogenic growth factors from the VEGF family and the receptors to which they bind (VEGFRs). Here, we present molecular mechanisms of angiogenesis and lymphangiogenesis exploited by tumors to progress and metastasise, with examples of antibody-based therapeutic agents directed at interfering with these processes. The expanding knowledge of vascular biology helps to explain some of the problems encountered in such therapies, that arise due to the redundancy in signaling networks controlling the formation of blood and lymphatic vessels, and lead to tumor drug resistance. Nonetheless, combined treatments and treatments focused on newly discovered proangiogenic and prolymphangiogenic factors give hope that more prominent therapeutic effects might be achieved in the future

Skin-sparing and nipple-sparing mastectomy with a positive sentinel node in patients with breast cancer

Introduction. A skin-sparing or nipple-sparing mastectomy is a surgical treatment that is increasingly used in the treatment of patients with breast cancer. More often women themselves decide or even ask to undergo this type of surgery. In our paper, we present the issue of combined treatment of 62 patients after nipple-sparing or skin-sparing mastectomy with a positive sentinel lymph node. Realisation of this type of surgery has further consequences in adjuvant treatment policies. Material and methods. The group of 62 previously untreated women with positive sentinel lymph nodes took part in this analysis. The individual plan of treatment was established for every patient by the multidisciplinary team according to the rules of the breast cancer unit. All patients were treated in the Holycross Cancer Centre in Kielce (in 2015–2018). Results. The early results show that proper qualification and realisation of oncological treatment is safe and effective. Severe complications appeared rarely. Conclusions. Skin-sparing or nipple-sparing mastectomy is a method of surgical treatment that is increasingly used in the treatment of patients with breast cancer. It should be remembered that the qualification for this type of procedure should be careful, and adjuvant treatment should be rationally planned. Our experience shows that it is an effective and safe method

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis.

Lymphatic vessels transport fluid, antigens, and immune cells to the lymph nodes to orchestrate adaptive immunity and maintain peripheral tolerance. Lymphangiogenesis has been associated with inflammation, cancer metastasis, autoimmunity, tolerance and transplant rejection, and thus, targeted lymphatic ablation is a potential therapeutic strategy for treating or preventing such events. Here we define conditions that lead to specific and local closure of the lymphatic vasculature using photodynamic therapy (PDT). Lymphatic-specific PDT was performed by irradiation of the photosensitizer verteporfin that effectively accumulates within collecting lymphatic vessels after local intradermal injection. We found that anti-lymphatic PDT induced necrosis of endothelial cells and pericytes, which preceded the functional occlusion of lymphatic collectors. This was specific to lymphatic vessels at low verteporfin dose, while higher doses also affected local blood vessels. In contrast, light dose (fluence) did not affect blood vessel perfusion, but did affect regeneration time of occluded lymphatic vessels. Lymphatic vessels eventually regenerated by recanalization of blocked collectors, with a characteristic hyperplasia of peri-lymphatic smooth muscle cells. The restoration of lymphatic function occurred with minimal remodeling of non-lymphatic tissue. Thus, anti-lymphatic PDT allows control of lymphatic ablation and regeneration by alteration of light fluence and photosensitizer dose