Da Implantação do Núcleo de Inovação Tecnológica às Estratégias da Gestão da Propriedade Intelectual: um estudo de caso na Agência de Inovação do Instituto Federal do Paraná

This work analyzes the strategies adopted by the Federal Institute of Paraná (IFPR), through its Innovation Agency, for the management of Intellectual Property (IP) from the creation of the Technological Innovation Centers (NITs) in 2017 implemented practices and expected challenges. The success metrics of the NITs from the Fortec report were used as the basis for evaluating the performance of the IFPR NITs. Methodologically, it is a basic, quali-quantitative, descriptive research, carried out through a case study. From the implementation of the IP management strategies, 148 invention communications were received in the period from 2017 to 2021. Of these, 95 filed and 34 were granted by the INPI, with emphasis on patents and computer programs. The main challenges identified are the need to adopt strategies to leverage licensing agreements and collaborative research contracts.Este trabalho analisa as estratégias adotadas pelo Instituto Federal do Paraná (IFPR), por meio de sua Agência de Inovação, para a gestão da Propriedade Intelectual (PI) a partir da criação dos Núcleos de Inovação Tecnológica (NITs) em 2017. O estudo compartilha práticas implementadas e desafios esperados. Foram utilizadas como base para a avaliação do desempenho dos NITs do IFPR as métricas de sucesso dos NITs do relatório Fortec. Metodologicamente trata-se de uma pesquisa básica, quali-quantitativa, descritiva, efetivada por meio de estudo de caso. A partir da implementação das estratégias de gestão da PI, 148 comunicações de invenção foram recebidas no período de 2017 a 2021. Destas, 95 foram protocoladas no INPI e 34 foram concedidas, com destaque para patentes e programas de computador. Os principais desafios identificados são a necessidade de adoção de estratégias para alavancar acordos de licenciamento e de contratos de pesquisa colaborativa

NÚCLEO DE INOVAÇÃO TECNOLÓGICA COM PERSONALIDADE JURÍDICA PRÓPRIA

The so-called Innovation Law, in force since 2004, provides for the possibility of Technological Innovation Centers (NITs) to adopt their own legal personality, as a way of enhancing the development of their activities and purposes. However, there are several types of non-profit private law legal nature existing in the Brazilian legal system that could be adopted. This article aims to identify and describe the types of legal personality that best serve the purposes of NITs, pointing out their advantages and benefits. Among the legal entities evaluated, the Support Associations and Foundations, qualified as Social Organizations (SO), would provide the best service to the pre-established legal purposes for the functioning of the NITs, such as greater financial and administrative autonomy, in addition to greater agility in the relationship, cooperation and transfer of knowledge generated in ICTs with other private and public entities.La denominada Ley de Innovación, vigente desde 2004, prevé la posibilidad de que los Centros de Innovación Tecnológica (NIT) adopten personalidad jurídica propia, como forma de potenciar el desarrollo de sus actividades y fines. Sin embargo, existen varios tipos de naturaleza jurídica de derecho privado sin fines de lucro existentes en el ordenamiento jurídico brasileño que podrían ser adoptados. Este artículo tiene como objetivo identificar y describir los tipos de personalidad jurídica que mejor sirven a los fines de las NIT, señalando sus ventajas y beneficios. Entre las personas jurídicas evaluadas, las Asociaciones y Fundaciones de Apoyo, calificadas como Organizaciones Sociales (SO), brindarían el mejor servicio a los fines legales preestablecidos para el funcionamiento de los NIT, tales como una mayor autonomía financiera y administrativa, además de mayor agilidad en la relación, cooperación y transferencia del conocimiento generado en las TIC con otras entidades públicas y privadas.A denominada Lei de Inovação, vigente desde 2004, prevê a possibilidade dos Núcleos de Inovação Tecnológica (NITs) adotarem uma personalidade jurídica própria, como forma de potencializar o desenvolvimento de suas atividades e finalidades. Entretanto, existem diversos tipos de natureza jurídica de direito privado sem fins lucrativos existentes no ordenamento jurídico brasileiro que poderiam ser adotados. Este artigo tem por objetivo identificar e descrever os tipos de personalidade jurídica que melhor atendem aos propósitos dos NITs, apontando suas vantagens e benefícios. Dentre as personalidades jurídicas avaliadas, as Associações e as Fundações de Apoio, qualificadas como Organizações Sociais (OS), proporcionariam o melhor atendimento às finalidades legais pré-estabelecidas para o funcionamento dos NITs, como por exemplo uma maior autonomia financeira e administrativa, além de uma maior agilidade no relacionamento, na cooperação e na transferência do conhecimento gerado nas ICTs com os demais entes privados e públicos.A denominada Lei de Inovação, vigente desde 2004, prevê a possibilidade dos Núcleos de Inovação Tecnológica (NITs) adotarem uma personalidade jurídica própria, como forma de potencializar o desenvolvimento de suas atividades e finalidades. Entretanto, existem diversos tipos de natureza jurídica de direito privado sem fins lucrativos existentes no ordenamento jurídico brasileiro que poderiam ser adotados. Este artigo tem por objetivo identificar e descrever os tipos de personalidade jurídica que melhor atendem aos propósitos dos NITs, apontando suas vantagens e benefícios. Dentre as personalidades jurídicas avaliadas, as Associações e as Fundações de Apoio, qualificadas como Organizações Sociais (OS), proporcionariam o melhor atendimento às finalidades legais pré-estabelecidas para o funcionamento dos NITs, como por exemplo uma maior autonomia financeira e administrativa, além de uma maior agilidade no relacionamento, na cooperação e na transferência do conhecimento gerado nas ICTs com os demais entes privados e públicos

Population Biology of Rhodnius domesticus Neiva & Pinto, 1923 (Hemiptera: Reduviidae) under Laboratory Conditions

The entire life cycle of Rhodnius domesticus, fed weekly on mice, was studied under controlled conditions. Aspects related to hatching, life time, mortality, feeding behaviour and fecundity for each stage of the insect life-cycle were evaluated. The hatching rate observed in 100 eggs was 57% and the mean time of hatching was 15.6 days. Forty-six nymphs (80.7%) completed the cycle and the mean time from NI to adult was 93.8 days. The average span in days for each stage was 12.4 for NI, 9.8 for NII, 14.2 for NIII, 16.8 for NIV and 25.0 for NV. The number of bloodmeals in each nymphal stage varied from 1 to 3. The mortality rate was 12.3% for NI, 3.5% for NII and 1.7% for NIII and NV nymphs. The mean number of eggs laid per female in a 9-month period was 333.1. Average adult survival rates were 287.6 +133 and 328 +73 days for males and females respectively

Comparação entre a imuno-separação magnética, acoplada à imunofluorescência, e as técnicas de Faust et al. e de Lutz para o diagnóstico de cistos de Giardia lamblia em fezes humanas

No presente trabalho, o desempenho da técnica de Imunoseparação Magnética, acoplada à Imunofluorescência (IMS-IFA), foi comparado com aqueles das técnicas parasitológicas de FAUST et al. e de Lutz na detecção de cistos de Giardia lamblia em fezes humanas. Foram processadas 127 amostras de fezes pelas três técnicas paralelamente e a detecção de cistos foi de 27,5% para IMS-IFA e de 15,7% para as técnicas de FAUST et al. e de Lutz concomitantemente. A análise dos resultados mostrou maior sensibilidade da IMS-IFA na detecção de cistos de G. lamblia quando comparada aos métodos de FAUST et al. e Lutz. A utilização desta metodologia como procedimento de rotina proporciona o processamento de várias amostras simultaneamente, além de aumentar a recuperação de cistos de G. lamblia e reduzir o tempo de estocagem das amostras.In the present study, the performance of Immunomagnetic Separation technique, coupled with Immunofluorescence (IMS-IFA), was compared with the FAUST et al. and Lutz parasitological techniques for the detection of Giardia lamblia cysts in human feces. One hundred and twenty-seven samples were evaluated by the three techniques at the same time showing a rate of cyst detection of 27.5% by IMS-IFA and 15.7% by both Faust et al. and Lutz techniques. Data analysis showed a higher sensitivity of IMS-IFA for the detection of G. lamblia cysts in comparison with the techniques of FAUST et al. and Lutz. The use of this methodology as a routine procedure enables the processing of many samples simultaneously, in order to increase recovery rate of G. lamblia cysts and reduce the time of sample storage

Trypanosoma rangeli Transcriptome Project: Generation and analysis of expressed sequence tags

Trypanosoma rangeli is an important hemoflagellate parasite of several mammalian species in Central and South America, sharing geographical areas, vectors and reservoirs with T. cruzi, the causative agent of Chagas disease. Thus, the occurrence of single and/or mixed infections, including in humans, must be expected and are of great importance for specific diagnosis and epidemiology. In comparison to several Trypanosomatidae species, the T. rangeli biology and genome are little known, reinforcing the needs of a gene discovery initiative. The T. rangeli transcriptome initiative aims to promote gene discovery through the generation of expressed sequence tags (ESTs) and Orestes (ORF ESTs) from both epimastigote and trypomastigote forms of the parasite, allowing further studies of the parasite biology, taxonomy and phylogeny

Composição química e avaliação da atividade antimicrobiana do óleo essencial das folhas de Piper malacophyllum (C. Presl.) C. DC.

This work reports the chemical composition as well as the antibacterial, antifungal and antiparasitic activities of the leaf essential oil from Piper malacophyllum. The oil was extracted by hydrodistillation and analyzed by GC-FID, GC-MS and polarimetry. Among the 28 compounds identified, (+)-camphor was the major constituent. The essential oil showed activity against most of the microorganisms tested, especially antifungal action, with a MIC of 500 µg mL-1 against Trichophyton mentagrophytes and Cryptococcus neoformans. This is the first study reporting the composition and biological properties of leaf essential oil from P. malacophyllum

Outbreak of avian malaria associated to multiple species of plasmodium in magellanic penguins undergoing rehabilitation in Southern Brazil

Avian malaria is a mosquito-borne disease caused by Plasmodium spp. Avian plasmodia are recognized conservationthreatening pathogens due to their potential to cause severe epizootics when introduced to bird populations with which they did not co-evolve. Penguins are considered particularly susceptible, as outbreaks in captive populations will often lead to high morbidity and rapid mortality. We used a multidisciplinary approach to investigate an outbreak of avian malaria in 28 Magellanic penguins (Spheniscus magellanicus) at a rehabilitation center during summer 2009 in Florianópolis, Brazil. Hemosporidian infections were identified by microscopic and molecular characterization in 64% (18/28) of the penguins, including Plasmodium (Haemamoeba) tejerai, Plasmodium (Huffia) elongatum, a Plasmodium (Haemamoeba) sp. Lineage closely related to Plasmodium cathemerium, and a Haemoproteus (Parahaemoproteus) sp. lineage closely related to Haemoproteus syrnii. P. tejerai played a predominant role in the studied outbreak and was identified in 72% (13/18) of the hemosporidian-infected penguins, and in 89% (8/9) of the penguins that died, suggesting that this is a highly pathogenic parasite for penguins; a detailed description of tissue meronts and lesions is provided. Mixed infections were identified in three penguins, and involved P. elongatum and either P. tejerai or P. (Haemamoeba) sp. that were compatible with P. tejerai but could not be confirmed. In total, 32% (9/28) penguins died over the course of 16 days despite oral treatment with chloroquine followed by sulfadiazine-trimethoprim. Hemosporidian infections were considered likely to have occurred during rehabilitation, probably from mosquitoes infected while feeding on local native birds, whereas penguin-mosquitopenguin transmission may have played a role in later stages of the outbreak. Considering the seasonality of the infection, rehabilitation centers would benefit from narrowing their efforts to preventavian malaria outbreaks to the penguins that are maintained throughout summerFAPESP 2009/53956-9, 2010/51801-5FAPEMIGCAPESCNP