De colônia de imigrantes a um polo gastronômico: uma pesquisa institucional documental

The organizational field is the result of interactions over time between organizations, individuals and the context in which they are inserted. The foundations of the new institutional theory allow this reading and, in this sense, the objective of this research was to identify which institutional factors influenced the formation of the Gastronomic Pole in the Santa Felicidade District, in the city of Curitiba, Capital of Paraná, Brazil. To achieve this purpose, the qualitative research strategy was used, in which documentary research on the tourist-gastronomic sector of the referred neighborhood was adopted as a method, considering a sectional profile with longitudinal evaluation, in the period from 1878 to 2020. The data collected were analyzed using the thematic content analysis technique and the analytical categories used were institutional entrepreneurship at the action level and institutions in the context. It was concluded that the institutional entrepreneurship performed by the social actors allowed the evolution of the organizational field in this location, enabling the formation of the investigated Gastronomic Pole.O campo organizacional é resultado de interações ao longo do tempo entre organizações, indivíduos e o próprio contexto onde estão inseridos. Os fundamentos da nova teoria institucional permitem essa leitura e, nesse sentido, o objetivo desta pesquisa foi identificar que fatores institucionais influenciaram a formação do Polo Gastronômico no Bairro de Santa Felicidade, na cidade de Curitiba, Capital do Paraná, Brasil. Para atingir este propósito, foi utilizada a estratégia de pesquisa qualitativa, na qual se adotou como método a pesquisa documental sobre o setor turístico-gastronômico do referido bairro, considerando um recorte seccional com avaliação longitudinal no período de 1878 a 2020. Os dados coletados foram analisados por meio da técnica de análise de conteúdo temática e as categorias analíticas utilizadas foram o empreendedorismo institucional no nível da ação e as instituições no contexto. Concluiu-se que o empreendedorismo institucional desempenhado pelos atores sociais permitiu a evolução do campo organizacional desta localidade, possibilitando a formação do Polo Gastronômico investigado

Traumatic fracture of the thoracic spine T1-T10

We describe the incidence, causes, management and prognosis of traumatic fractures of the thoracic spine from T1 to T10 in surgical cases of traumatic fractures of spine during the period from June 1994 to June 2003 studied retrospectively. The type of fracture was determined according to the Gertzbein classification, and the degree of stability using the Denis classification. The neurological picture at admission and 30 days after surgery was evaluated using the ASIA/IMSOP classification. Surgery was performed in patients with complete spinal cord injury (n=7) for the purpose of stabilization using the posterior approach. In cases without spinal cord injury or incomplete injury (n=12), the surgical procedure was performed aiming to decompress the nerve tissue, to correct the alignment of the spine and to stabilize the spine.Descrevemos a incidência, causas, manejo e prognóstico das fraturas traumáticas de coluna torácica de T1 a T10. Estudamos retrospectivamente os casos cirúrgicos de fraturas traumáticas da coluna torácica (T1 a T10), durante o período de junho de 1994 a junho de 2003. O tipo de fratura foi determinado segundo a classificação de Gertzbein e o grau de estabilidade através da classificação de Denis. O quadro neurológico à internação e 30 dias após a cirurgia foi avaliado através da classificação de ASIA/IMSOP. O objetivo da cirurgia nos pacientes com lesão medular completa (n=7) foi de estabilização, enquanto nos casos de instabilidade vertebral em que não houve lesão medular ou esta foi incompleta (n=12), optou-se pela descompressão do tecido nervoso, correção do alinhamento da coluna e estabilização da coluna.Universidade de Caxias do SulUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUNIFESP, EPMSciEL

Mycobacterium avium subesp. paratuberculosis: uma preocupação para a indústria de laticínios

Mycobacterium avium subesp. paratuberculosis é conhecida como o agente etiológico da doença de Johne, ou paratuberculose, que afeta principalmente animais ruminantes. É integrante da família Mycobacteriaceae, da qual também fazem parte a M. tuberculosis e a M. bovis, responsáveis pela tuberculose humana e bovina, respectivamente. Foi sugerido que a M. paratuberculosis poderia estar envolvida na patogênese da doença de Crohn, a qual possui sintomas similares à paratuberculose, mas afeta seres humanos. Como o microrganismo pode ser excretado no leite de animais infectados, o primeiro passo foi avaliar a sua termoresistência. Alguns estudos indicaram que a bactéria sobrevive ao tratamento térmico da pasteurização HTST (72ºC/15 s). Entretanto, os estudos existentes na literatura científica até o momento não permitem afirmar que M. paratuberculosis seja responsável pela doença de Crohn, bem como apresentam dúvidas sobre a termoresistência dessa bactéria. A realização de mais pesquisas sobre este microrganismo é de fundamental importância, com o objetivo de orientar a produção de produtos lácteos isentos de contaminação por M. paratuberculosis

Fibrinólise com infusão de rtPA e drenagem estereotáxica de hematoma intracerebral espontâneo profundo

PURPOSE: The authors present a prospective study on 10 patients with stereotactic infusion of tissue plasminogen activator (rtPA) intraparenchimal hemorrhage. METHODS: Between 1999 and 2000, 10 patients with deep seated hematomas in the basal ganglia were selected for stereotactic infusion of rtPA and spontaneous clot drainage. RESULTS: All cases had about 80% reduction of the hematoma volume in the CT scan at the third day. The intracranial pressure was normalized by the third day too. There were no local or systemic complications with the use of this trombolitic. The results were shown by the Glasgow Outcome Scale with six patients in V, three in IV and one in III after 3 months. CONCLUSION: Early treatment and drainage with minimally invasive neurosurgery , can make these patients with deep-seated hematomas recover the consciousness and they can be rehabilitated earlier avoiding secondary complications.OBJETIVO: Estudo prospectivo em 10 pacientes com infusão de trombolítico (rtPA) dentro do hematoma cerebral profundo supratentorial e drenagem estereotáxica. MÉTODO: Entre 1999 e 2000 10 pacientes com hematomas de profundidade foram selecionados para infusão de rtPA e drenagem do coágulo espontânea. RESULTADO: Todos os casos obtiveram 80% de redução do volume do hematoma medidos por TC no terceiro dia. A pressão intracraniana estava normalizada no terceiro dia. Não houve complicações locais ou sistêmicas relacionadas com o uso deste trombolítico. Os resultados comparados foram mostrados pela Escala de Prognóstico de Glasgow com 6 pacientes em GrauV, 3 pacientes em Grau IV e 1 paciente em Grau III após três meses. CONCLUSÃO: Tratamento precoce e drenagem com técnica neurocirúrgica minimamente invasiva pode fazer estes pacientes terem uma recuperação da consciência mais rápida e assim serem reabilitados mais precocemente evitando complicações secundárias.Universidade Estácio de Sá Instituto do Sono Estácio de Sá Centro de Investigação NeurológicaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUNIFESP, EPMSciEL

Effect of bleaching gels with different thickeners under normal and hyposalivation conditions: : in situ study

Bleaching gel thickeners induce important changes in tooth enamel and these changes are reversed by saliva. Objective: This in situ study aimed to evaluate the effect of bleaching gels with different thickeners on tooth enamel under normal and hyposalivation conditions. MethodologyOf 28 participants, 14 had normal salivary flow and 14 had low salivary flow. For each salivary flow, four types of treatment were performed with different thickeners: no bleaching (negative control), bleaching with a commercial 10% carbamide peroxide (CP) gel with carbopol (positive control) and bleaching with experimental 10% CP gels with natrosol and aristoflex. Participants used a palatal appliance containing bovine enamel/dentin specimens for 15 days. From day 2 to day 15, specimens were bleached extraorally. The bleaching gel was applied according to the groups for four hours. When the bleaching gel was removed, the palatal appliance was inserted again in the participants’ mouth until the next day for another bleaching application. This procedure was repeated for 14 days and on day 15, surface microhardness (SMH), color (ΔE*ab and ΔE00), surface roughness (Ra), scanning electron microscopy (SEM), and energy-dispersive X-ray spectrometry (EDS) analyses were performed and data were subjected to statistical analysis. Results: Neither salivary flow nor thickeners influenced ΔE*ab and ΔE00 results. Carbopol had the lowest SMH, the highest Ra, and the lowest Ca% among all groups. For normal flow, natrosol and aristoflex had higher SMH. For low flow, aristoflex had higher SMH and natrosol and aristoflex had lower Ra. Aristoflex had higher Ca% and Ca/P and differed from carbopol for normal flow. Conclusion: For normal flow, 10% CP gels with natrosol and aristoflex caused fewer surface changes, and for low flow, only the 10% CP gel with aristoflex

Chemical composition and enzymatic digestibility of sugarcane clones selected for varied lignin content

<p>Abstract</p> <p>Background</p> <p>The recalcitrance of lignocellulosic materials is a major limitation for their conversion into fermentable sugars. Lignin depletion in new cultivars or transgenic plants has been identified as a way to diminish this recalcitrance. In this study, we assessed the success of a sugarcane breeding program in selecting sugarcane plants with low lignin content, and report the chemical composition and agronomic characteristics of eleven experimental hybrids and two reference samples. The enzymatic digestion of untreated and chemically delignified samples was evaluated to advance the performance of the sugarcane residue (bagasse) in cellulosic-ethanol production processes.</p> <p>Results</p> <p>The ranges for the percentages of glucan, hemicellulose, lignin, and extractive (based on oven-dry biomass) of the experimental hybrids and reference samples were 38% to 43%, 25% to 32%, 17% to 24%, and 1.6% to 7.5%, respectively. The samples with the smallest amounts of lignin did not produce the largest amounts of total polysaccharides. Instead, a variable increase in the mass of a number of components, including extractives, seemed to compensate for the reduction in lignin content. Hydroxycinnamic acids accounted for a significant part of the aromatic compounds in the samples, with <it>p</it>-coumaric acid predominating, whereas ferulic acid was present only in low amounts. Hydroxycinnamic acids with ester linkage to the hemicelluloses varied from 2.3% to 3.6%. The percentage of total hydroxycinnamic acids (including the fraction linked to lignin through ether linkages) varied from 5.0% to 9.2%, and correlated to some extent with the lignin content. These clones released up to 31% of glucose after 72 hours of digestion with commercial cellulases, whereas chemically delignified samples led to cellulose conversion values of more than 80%. However, plants with lower lignin content required less delignification to reach higher efficiencies of cellulose conversion during the enzymatic treatment.</p> <p>Conclusion</p> <p>Some of the experimental sugarcane hybrids did have the combined characteristics of high biomass and high sucrose production with low lignin content. Conversion of glucan to glucose by commercial cellulases was increased in the samples with low lignin content. Chemical delignification further increased the cellulose conversion to values of more than 80%. Thus, plants with lower lignin content required less delignification to reach higher efficiencies of cellulose conversion during the enzymatic treatment.</p

ATIVIDADE FÍSICA, DIABETES E OBESIDADE NAS AULAS DE EDUCAÇÃO FÍSICA: PERCEPÇÕES DE ESCOLARES DO 7º ANO

This study seeks to understand how students see the triad of the physical activity, diabetes and obesity in relation to the health in school physical education classes. The study involved 15 schoolchildren of both sexes of the seventh grade of the elementary school, at a state school in the city of Alegrete (RS). It was using a questionnaire in two occasions: before and after of the pedagogical intervention with duration a total of twenty class/ hours. During the intervention period, the theoretical classes prevailed and they involve a presentation of videos and issues related with obesity, diabetes and physical activity. The results demonstrated the students didn’t show significant differences in the answers in both tests about the Diabetes. About the Obesity, the students showed a clearer concept and more consistent by the end of the period. For the risk factors associated with obesity, there was a higher concentration of responses which were related to obesity to the poor diet and to physical inactivity. Then, it was possible to identify a wider distribution in regard the different risk factors. Thus, we observed that among students there is an association between physical activity and the diseases prevention, especially diabetes and obesity

Assessment of stage T1 (TNM 1997) for renal cell carcinoma: is recommended the subdivision in T1a and T1b?

INTRODUCTION: Classification TNM 1997 defines renal cell carcinoma smaller than 7 cm and confined to the kidney as stage T1. Our goal is to discuss if tumors smaller than 4 cm have the same behavior characteristics then tumors between 4 and 7 cm, to compose the same stage of the disease. MATERIALS AND METHODS: Retrospective assessment of 138 patients in stage T1 (TNM - 97), divided into 2 groups; group-1: composed of 65 patients (47%) with tumors < 4 cm, and group-2: composed of 73 patients (53%) with tumors between 4 and 7 cm. The following prognostic factors were assessed in the recurrence of the disease and survival of patients: nuclear degree, microvascular invasion, sarcomatous degeneration, and involved lymph nodes. Statistical evaluation has been accomplished through the log rank test, chi-square test, and Fishers exact text. RESULTS: Average tumor size was 2.5 cm for group-1, and 5.3 cm for group-2. In group-2, there was the predominance of worse prognostic factors, with high-grade tumors (p = 0.01) and presence of microvascular invasion (p = 0.001). Sarcomatous tumors and involvement of lymph nodes did only happen in group-2. Disease-free survival for group-1, analyzed in the median period of 36 months, was 100%, and for group 2, in the median period of 31 months, was 81% (p = 0.008). CONCLUSION: The results obtained allow the conclusion that the present stage T1 for renal cell carcinoma gathers tumors of different evolution, being therefore recommendable the stratification in T1a for tumors smaller than 4 cm, and T1b for tumors between 4 and 7 cm.Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Divisions of Urology and StatisticsUNIFESP, EPM, Divisions of Urology and StatisticsSciEL