428 research outputs found

    Can you believe what you see? A qualitative study about the determinants affecting the perceived credibility of video eWOM

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    Thesis Purpose: With the increasing popularity of social networks like YouTube, and the increasing accessibility of consumers to devices able to make and edit videos, video reviews are facing a remarkable growth. Hitherto, the research in eWOM has paid more attention to written reviews, leaving a notable gap of research in video eWOM. The purpose of this study was to improve the knowledge about video eWOM, studying the determinants affecting the perceived credibility of video reviews. Indeed, credibility is a crucial factor, playing a significant role in the consumer’s attitude toward a brand or product, and the consequent purchase intention. The study reached an answer to the following question: What are the determinants affecting the perceived credibility of video-eWOM reviews? Theoretical Perspective: The research model, adopted in this study, built upon three (3) main theoretical areas, due to a lack of research in video eWOM and in order to formulate an adequate background, suitable for the interpretation and analysis of data. First, the study drew upon the determinants of perceived credibility, found by prior research in the field of written eWOM. With the purpose of facilitating the use of this theory, it was built a comprehensive model, summarising all the determinants. Second, some theories about the influence of video features on the audience were implemented in order to fully grasp the potentiality of video reviews. Finally, the third area was focused on the peculiar features of nonverbal communication, involved in video reviews through the adoption of images, motion and sound to convey the message. Methodology: The empirical research was performed through a qualitative study based on a variation grounded theory. The data was collected at one point in time, and the sample consisted in 12 female participants who interacted with five (5) video reviews on YouTube. The participants’ opinions were collected performing semi-structured interviews, supported by the techniques of photo elicitation and list of thoughts. The empirical data was then analysed through a sequence of definite steps, based on grounded analysis. Results: The results of the empirical research were summarised in a new model, encompassing all the determinants observed to exert an influence in the current study. Two (2) new determinants of perceived credibility – visual evidence and testing – were revealed along with one (1) new moderator, first impression. Besides, the determinants and moderators, corresponding to the ones of written eWOM, were assessed by the participants through the adoption of more cues, including the reviewer’s appearance, facial expressions, tone of voice, and video features (e.g. setting). Keywords: Video eWOM, Video reviews, Electronic word-of-mouth, Credibility, YouTube

    New results about early therapeutic hypothermia in sudden cardiac death and following return of spontaneous circulation

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    in this paper the authors review the results of therapeutic hypothermia in patient with rosc following sudden cardia arres

    The role of corporate social responsibility in the wine industry: The case study of veneto and friuli venezia giulia

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    This study aimed to investigate the awareness of Corporate Social Responsibility (CSR) among wineries located in the Italian regions of Veneto and Friuli Venezia Giulia (FVG) (1), (2) the obstacles (3) and market drivers of its implementation (4), the practices and range of actions that are concretely implemented in the field of CSR (5), the implications that this management approach can have on company performance (6), and the communication tools used. The methodology adopted is based on a qualitative approach integrated with quantitative measures. In total, 28 wineries participated in the study. The results show that all of the wineries were aware of the importance of implementing CSR, although they mainly refer to environmental issues. Sponsorship in fair trade activities is considered the most relevant market driver, while Italian consumers are generally perceived as not particularly interested in sustainable wine production. The practices implemented are mainly focused on reducing environmental impact. Interesting insights have emerged from this study, such as an unusual disparity between theoretical knowledge and practical implementation of socially responsible activities, a tendency to adapt the entrepreneurial style towards CSR, as well as a fundamental willingness to implement good practices that go beyond the legal requirements currently in force

    An Efficient Artificial Intelligence Energy Management System for Urban Building Integrating Photovoltaic and Storage

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    The emerging leading role of green energy in our society pushes the investigation of new economic and technological solutions. Green energies and smart communities increase efficiency with the use of digital solutions for the benefits of inhabitants and companies. The paper focuses on the development of a methodology for the energy management, combining photovoltaics and storage systems, considering as the main case study a multi-story building characterized by a high density of households, used to generate data which allow feasibility foresights. The physical model of the algorithm is composed by two main elements: the photovoltaics modules and the battery energy storage system. In addition, to gain information about the real-time consumption a machine learning module is included in our approach to generate predictions about the near future demand. The benefits provided by the method are evaluated with an economic analysis, which computes the return of the investment using the real consumptions of a Boarding School, located in Turin (Italy). The case study analyzed in this article showed an increase in purchased energy at the minimum price from 25% to 91% and a 55% reduction in the electricity bill compared to most solutions on the market, with no additional costs and a stabilizing effect on the grid. Finally, the economic analysis shows that the proposed method is a profitable investment, with a breakeven point of thirteen years, due to the very simple implementation and the zero additional cost requested

    Publisher Correction: Prokineticin receptor 2 affects GnRH3 neuron ontogeny but not fertility in zebrafish

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    An amendment to this paper has been published and can be accessed via a link at the top of the paper

    Bone marrow mesenchymal stem cells as nuclear donors improve viability and health of cloned horses

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    Introduction: Cell plasticity is crucial in cloning to allow an efficient nuclear reprogramming and healthy offspring. Hence, cells with high plasticity, such as multipotent mesenchymal stem cells (MSCs), may be a promising alternative for horse cloning. In this study, we evaluated the use of bone marrow-MSCs (BM-MSCs) as nuclear donors in horse cloning, and we compared the in vitro and in vivo embryo development with respect to fibroblasts. Materials and methods: Zona-free nuclear transfer was performed using BM-MSCs (MSC group, n=3432) or adult fibroblasts (AF group, n=4527). Embryos produced by artificial insemination (AI) recovered by uterine flushing and transferred to recipient mares were used as controls (AI group). Results: Blastocyst development was higher in the MSC group than in the AF group (18.1% vs 10.9%, respectively; p<0.05). However, pregnancy rates and delivery rates were similar in both cloning groups, although they were lower than in the AI group (pregnancy rates: 17.7% [41/232] for MSC, 12.5% [37/297] for AF and 80.7% [71/88] for AI; delivery rates: 56.8% [21/37], 41.5% [17/41] and 90.1% [64/71], respectively). Remarkably, the gestation length of the AF group was significantly longer than the control (361.7}10.9 vs 333.9}8.7 days), in contrast to the MSC group (340.6}8.89 days). Of the total deliveries, 95.2% (20/21) of the MSC-foals were viable, compared to 52.9% (9/17) of the AF-foals (p<0.05). In addition, the AF-foals had more physiological abnormalities at birth than the MSC-foals; 90.5% (19/21) of the MSC-delivered foals were completely normal and healthy, compared to 35.3% (6/17) in the AF group. The abnormalities included flexural or angular limb deformities, umbilical cord enlargement, placental alterations and signs of syndrome of neonatal maladjustment, which were treated in most cases. Conclusion: In summary, we obtained 29 viable cloned foals and found that MSCs are suitable donor cells in horse cloning. Even more, these cells could be more efficiently reprogrammed compared to fibroblasts.Fil: Olivera, R.. Kheiron Sa.; ArgentinaFil: Moro, Lucía Natalia. Laboratorio de Investigaciones en Neurociencias Aplicadas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Jordan, R.. Kheiron Sa.; ArgentinaFil: Pallarols, N.. Kawell Hospital Equino; ArgentinaFil: Guglielminetti, A.. Kawell Hospital Equino; ArgentinaFil: Luzzani, Carlos Daniel. Laboratorio de Investigaciones en Neurociencias Aplicadas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Miriuka, Santiago Gabriel. Laboratorio de Investigaciones en Neurociencias Aplicadas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vichera, Gabriel Damian. Kheiron Sa.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry

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    Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the first experimental result where the use of in situ click chemistry has been successfully applied to probe the ligand-binding site of Abl and the ability of this enzyme to form its inhibitor. Docking studies show that Abl is able to allow the in situ click chemistry between specific azide and alkyne fragments by binding to Abl-active sites. This report allows medicinal chemists to use protein-directed in situ click chemistry for exploring the conformational space of a ligand-binding pocket and the ability of the protein to guide its inhibitor. This approach can be a novel, valuable tool to guide drug design synthesis in the field of tyrosine kinases

    Generation of iPSC line iPSC-FH2.1 in hypoxic conditions from human foreskin fibroblasts

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    AbstractHuman foreskin fibroblasts were used to generate the iPSC line iPSC-FH2.1 using the EF1a-hSTEMCCA-loxP vector expressing OCT4, SOX2, c-MYC and KLF4, in 5% O2 culture conditions. Stemness was confirmed, as was pluripotency both in vivo and in vitro, in normoxia and hypoxia. Human Embryonic Stem Cell (hESC) line WA-09 and reprogrammed fibroblast primary culture HFF-FM were used as controls
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