1,535 research outputs found

    The United States- Argentina honey case and the case against antidumping laws

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    The failure of the Fifth Ministerial Conference in Cancun2 was not only a setback for the Doha Round, but also for the World Trade Organization’s efforts to enhance international trade as means to growth and development. The group of developing countries led by Brazil, China, India and South Africa, known as G-22, made the first step towards a new balance in the multilateral trading system. Agriculture was considered a key issue if the new Round was meant to succeed. It will certainly take time and a great deal of political will to get countries back to the negotiating table, but the benefits will outweigh the costs. Substantial poverty reduction in the world will be achieved by tackling agricultural protection. Poor countries mainly produce agricultural products and intensive labor products such as textiles usually facing protective – developed markets. Subsidies in the OECD account for more than US$ 300,000 million targeted at agricultural products originatingin developing countries. Annual subsidies at the OECD are equivalent to six times the direct economic aid those countries provide for the poor countries.3 Developing countries are responsible for seriously committing themselves and reducing agricultural barriers – tariff and non- tariff – in order to facilitate trade liberalization towards an equity free trade world. Párrafo extraído del texto a modo de resumenÁrea temática: Relaciones económicas internacionales."Comercio e integración regional"Instituto de Relaciones Internacionale

    The United States-Argentina honey case and the case against antidumping laws

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    The failure of the Fifth Ministerial Conference in Cancun2 was not only a setback for the Doha Round, but also for the World Trade Organization’s efforts to enhance international trade as means to growth and development. The group of developing countries led by Brazil, China, India and South Africa, known as G-22, made the first step towards a new balance in the multilateral trading system. Agriculture was considered a key issue if the new Round was meant to succeed. (Párrafo extraído del texto a modo de resumen)Instituto de Relaciones Internacionales (IRI

    Kinetics and Inhibition Studies of the L205R Mutant of cAMP-Dependent Protein Kinase Involved in Cushing’s Syndrome

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    Overproduction of cortisol by the hypothalamus–pituitary–adrenal hormone system results in the clinical disorder known as Cushing\u27s syndrome. Genomics studies have identified a key mutation (L205R) in the α‐isoform of the catalytic subunit of cAMP‐dependent protein kinase (PKACα) in adrenal adenomas of patients with adrenocorticotropic hormone‐independent Cushing\u27s syndrome. Here, we conducted kinetics and inhibition studies on the L205R‐PKACα mutant. We have found that the L205R mutation affects the kinetics of both Kemptide and ATP as substrates, decreasing the catalytic efficiency (kcat/KM) for each substrate by 12‐fold and 4.5‐fold, respectively. We have also determined the IC50 and Ki for the peptide substrate‐competitive inhibitor PKI(5–24) and the ATP‐competitive inhibitor H89. The L205R mutation had no effect on the potency of H89, but causes a \u3e 250‐fold loss in potency for PKI(5–24). Collectively, these data provide insights for the development of L205R‐PKACα inhibitors as potential therapeutics

    The United States- Argentina honey case and the case against antidumping laws

    Get PDF
    The failure of the Fifth Ministerial Conference in Cancun2 was not only a setback for the Doha Round, but also for the World Trade Organization’s efforts to enhance international trade as means to growth and development. The group of developing countries led by Brazil, China, India and South Africa, known as G-22, made the first step towards a new balance in the multilateral trading system. Agriculture was considered a key issue if the new Round was meant to succeed. It will certainly take time and a great deal of political will to get countries back to the negotiating table, but the benefits will outweigh the costs. Substantial poverty reduction in the world will be achieved by tackling agricultural protection. Poor countries mainly produce agricultural products and intensive labor products such as textiles usually facing protective – developed markets. Subsidies in the OECD account for more than US$ 300,000 million targeted at agricultural products originatingin developing countries. Annual subsidies at the OECD are equivalent to six times the direct economic aid those countries provide for the poor countries.3 Developing countries are responsible for seriously committing themselves and reducing agricultural barriers – tariff and non- tariff – in order to facilitate trade liberalization towards an equity free trade world. Párrafo extraído del texto a modo de resumenÁrea temática: Relaciones económicas internacionales."Comercio e integración regional"Instituto de Relaciones Internacionale

    Proceedings of the inaugural International Summit for Medical Nutrition Education and Research

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    © 2016 The Royal Society for Public Health Medical Nutrition Education (MNE) has been identified as an area with potential public health impact. Despite countries having distinctive education systems, barriers and facilitators to effective MNE are consistent across borders, demanding a common platform to initiate global programmes. A shared approach to supporting greater MNE is ideal to support countries to work together. In an effort to initiate this process, the Need for Nutrition Education/Innovation Programme group, in association with their strategic partners, hosted the inaugural International Summit on Medical Nutrition Education and Research on August 8, 2015 in Cambridge, UK. Speakers from the UK, the USA, Canada, Australia, New Zealand, Italy, and India provided insights into their respective countries including their education systems, inherent challenges, and potential solutions across two main themes: (1) Medical Nutrition Education, focused on best practice examples in competencies and assessment; and (2) Medical Nutrition Research, discussing how to translate nutrition research into education opportunities. The Summit identified shared needs across regions, showcased examples of transferrable strategies and identified opportunities for collaboration in nutrition education for healthcare (including medical) professionals. These proceedings highlight the key messages presented at the Summit and showcase opportunities for working together towards a common goal of improvement in MNE to improve public health at large

    The United States-Argentina honey case and the case against antidumping laws

    Get PDF
    The failure of the Fifth Ministerial Conference in Cancun2 was not only a setback for the Doha Round, but also for the World Trade Organization’s efforts to enhance international trade as means to growth and development. The group of developing countries led by Brazil, China, India and South Africa, known as G-22, made the first step towards a new balance in the multilateral trading system. Agriculture was considered a key issue if the new Round was meant to succeed. (Párrafo extraído del texto a modo de resumen)Instituto de Relaciones Internacionales (IRI

    Partial-Body Cryotherapy Acutely Augments Resting Metabolism in Obese Women

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    Cryotherapy has been shown to reduce pro-inflammatory response, relieve pain and enhance muscles\u2019 post-exercise recovery. Cryostimulation could be also proposed as an alternative strategy to trigger cold-induced thermogenesis in overweight/obese subjects. In this study, 16 obese (BMI: 32\ub14 kg/m2) women (43.4\ub14.8 years) underwent Partial-Body Cryotherapy (PBC) (-130\ub0C x 150sec) for 5 days (1/day, h 07:00 AM). Resting energy metabolism (REE) was assessed by indirect calorimetry pre- and post-PBC on day 1 and day 5. Subjects were energy-controlled (physical activity and dietary intake). Before 5th-day PBC, REE was increased by 5.5% versus pre-1st-day PBC values (1755\ub1265 vs. 1664\ub1241 kcal/day; p=0.0005). With a similar design, in a larger sample of 80 subjects (F=61; M=19; 34.4\ub111.1 years; BMI: 24.4\ub14.8 kg/m2), REE augmented by 1.89% (p=0.02) after PBC of day 1. In a multivariate analysis, multiple regression output a positive relationship between cryostimulated REE and body weight (Spearman r=0.68; p<0.0001, Figure). Altogether, these preliminary data suggest that cold-induced thermogenesis could be explored as an alternative therapy to combat weight gain and obesity. Longitudinal studies could test chronic effects of cryotherapy, estimating the extent of the metabolic adaptations that could be favorably preserved

    Linux Based Ethernet Communication for Xilinx FPGAs

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    This article presents the implementation of an Ethernet communication platform for use on Xilinx FPGAs. The proposed solution relies on a synthesized embedded system to provide network data transfer and control capabilities, for use with synthesizable electronic devices. Most TCP/IP stack services and protocols were implemented and the design is flexible to allow adaptation and/or expansion for different application scenarios. Currently this platform is being used on the development of a FPGA based JTAG controller, with remote access. The embedded system hardware requires a MicroBlaze softcore microprocessor running a Petalinux operating system.info:eu-repo/semantics/publishedVersio

    Evaluation of skin temperature change as stress indicator in rabbit through infrared thermography

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    AbstractStress-induced reactions in animals include behavioural and physiological modifications aiming at coping towards the stressor, such as manipulations. Thermography, that is the detection of ..
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