Topographic Wetness Index as a Proxy for Soil Moisture : The Importance of Flow-Routing Algorithm and Grid Resolution

The Topographic Wetness Index (TWI) is a commonly used proxy for soil moisture. The predictive capability of TWI is influenced by the flow-routing algorithm and the resolution of the Digital Elevation Model (DEM) that TWI is derived from. Here, we examine the predictive capability of TWI using 11 flow-routing algorithms at DEM resolutions 1-30 m. We analyze the relationship between TWI and field-quantified soil moisture using statistical modeling methods and 5,200 study plots with over 46 000 soil moisture measurements. In addition, we test the sensitivity of the flow-routing algorithms against vertical height errors in DEM at different resolutions. The results reveal that the overall predictive capability of TWI was modest. The highest r(2) (23.7%) was reached using a multiple-flow-direction algorithm at 2 m resolution. In addition, the test of sensitivity against height errors revealed that the multiple-flow-direction algorithms were also more robust against DEM errors than single-flow-direction algorithms. The results provide field-evidence indicating that at its best TWI is a modest proxy for soil moisture and its predictive capability is influenced by the flow-routing algorithm and DEM resolution. Thus, we encourage careful evaluation of algorithms and resolutions when using TWI as a proxy for soil moisture.Peer reviewe

Topographic Wetness Index as a Proxy for Soil Moisture : The Importance of Flow-Routing Algorithm and Grid Resolution

The Topographic Wetness Index (TWI) is a commonly used proxy for soil moisture. The predictive capability of TWI is influenced by the flow-routing algorithm and the resolution of the Digital Elevation Model (DEM) that TWI is derived from. Here, we examine the predictive capability of TWI using 11 flow-routing algorithms at DEM resolutions 1-30 m. We analyze the relationship between TWI and field-quantified soil moisture using statistical modeling methods and 5,200 study plots with over 46 000 soil moisture measurements. In addition, we test the sensitivity of the flow-routing algorithms against vertical height errors in DEM at different resolutions. The results reveal that the overall predictive capability of TWI was modest. The highest r(2) (23.7%) was reached using a multiple-flow-direction algorithm at 2 m resolution. In addition, the test of sensitivity against height errors revealed that the multiple-flow-direction algorithms were also more robust against DEM errors than single-flow-direction algorithms. The results provide field-evidence indicating that at its best TWI is a modest proxy for soil moisture and its predictive capability is influenced by the flow-routing algorithm and DEM resolution. Thus, we encourage careful evaluation of algorithms and resolutions when using TWI as a proxy for soil moisture.Peer reviewe

Tracking the Limnoecological History of Lake Hiidenvesi (Southern Finland) Using the Paleolimnological Approach

Correction: Water, Air and Soil Pollution, 230 :9 (2019), art. 228 DOI: 10.1007/s11270-019-4262-2We examined a sediment record from Lake Hiidenvesi in southern Finland using paleolimnological methods to trace its limnoecological history. In our record, beginning from the 1940s, chironomid (Diptera) assemblages shifted from typical boreal taxa towards mesotrophic community assemblages at similar to 1960-1980 CE being finally replaced by eutrophic taxa from the 1990s onward. The diatom (Bacillariophyceae) assemblages reflected relatively nutrient rich conditions throughout the record showing a further increase in eutrophic taxa from the 1970s onward. A chironomid-based reconstruction of late-winter hypolimnetic dissolved oxygen (DO) conditions suggested anoxic conditions already in the 1950s, probably reflecting increased inlake production due to allochthonous nutrient inputs and related increase in biological oxygen consumption. However, the reconstruction also indicated large variability in long-term oxygen conditions that appear typical for the basin. With regard to nutrient status, chironomid- and diatom-based reconstructions of total phosphorus (TP) showed a similar trend throughout the record, although, chironomids indicated a more straightforward eutrophication process in the benthic habitat and seemed to reflect the intensified human activities in the catchment more strongly than diatoms. The DO and TP reconstructions were mostly similar in trends compared to the measured data available since the 1970s/1980s. However, the increase in TP during the most recent years in both reconstructions was not visible in the monitored data. The results of our multiproxy study emphasize the significance of including both epilimnetic and hypolimnetic systems in water quality assessments and provide important long-term limnoecological information that will be useful in the future when setting targets for restoration.Peer reviewe

CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques

Introduction APOE is the strongest risk gene for sporadic Alzheimer's disease (AD) so far. Recent genome wide association studies found links for sporadic AD with CLU and CR1 involved in Aβ clearance, and PICALM affecting intracellular trafficking. Methods We investigated the associations of senile plaques (SP) and neurofibrillary tangles (NFT) with the proposed risk genes and APOE, in the Tampere Autopsy Study (TASTY) series (603 cases), a sample of the general population (0 to 97 yrs), who died out-of-hospital. Results Age and the APOEε4 allele associated strongly with all phenotypes of SP, as expected. In age and APOEε4 adjusted analyses, compared to the most common homozygous genotype, burnt out SP were more common among carriers of the C-allele of CLU, whereas the T-allele of PICALM and C-allele of CR1 were linked with lower SP coverage. We found no significant associations between any of the genetic variants and NFT. Conclusions Marginal effects from CLU, CR1 and PICALM suggest that these genes have minimal effects on the development of AD lesions.BioMed Central Open acces

Two independent evolutionary routes to Na+/H+ cotransport function in membrane pyrophosphatases.

Membrane-bound pyrophosphatases (mPPases) hydrolyze pyrophosphate (PPi) to transport H(+), Na(+) or both and help organisms to cope with stress conditions, such as high salinity or limiting nutrients. Recent elucidation of mPPase structure and identification of subfamilies that have fully or partially switched from Na(+) to H(+) pumping have established mPPases as versatile models for studying the principles governing the mechanism, specificity and evolution of cation transporters. In the present study, we constructed an accurate phylogenetic map of the interface of Na(+)-transporting PPases (Na(+)-PPases) and Na(+)- and H(+)-transporting PPases (Na(+),H(+)-PPases), which guided our experimental exploration of the variations in PPi hydrolysis and ion transport activities during evolution. Surprisingly, we identified two mPPase lineages that independently acquired physiologically significant Na(+) and H(+) cotransport function. Na(+),H(+)-PPases of the first lineage transport H(+) over an extended [Na(+)] range, but progressively lose H(+) transport efficiency at high [Na(+)]. In contrast, H(+)-transport by Na(+),H(+)-PPases of the second lineage is not inhibited by up to 100 mM Na(+) With the identification of Na(+),H(+)-PPase subtypes, the mPPases protein superfamily appears as a continuum, ranging from monospecific Na(+) transporters to transporters with tunable levels of Na(+) and H(+) cotransport and further to monospecific H(+) transporters. Our results lend credence to the concept that Na(+) and H(+) are transported by similar mechanisms, allowing the relative efficiencies of Na(+) and H(+) transport to be modulated by minor changes in protein structure during the course of adaptation to a changing environment. </p

Serum Neurofilament Light Is Elevated Differentially in Older Adults with Uncomplicated Mild Traumatic Brain Injuries

Neurofilament light (NF-L) might have diagnostic and prognostic potential as a blood biomarker for mild traumatic brain injury (mTBI). However, elevated NF-L is associated with several neurological disorders associated with older age, which could confound its usefulness as a traumatic brain injury biomarker. We examined whether NF-L is elevated differentially following uncomplicated mTBI in older adults with pre-injury neurological disorders. In a case-control study, a sample of 118 adults (mean age = 62.3 years, standard deviation [SD] = 22.5, range = 18-100; 52.5% women) presenting to the emergency department (ED) with an uncomplicated mTBI were enrolled. All participants underwent head computed tomography in the ED and showed no macroscopic evidence of injury. The mean time between injury and blood sampling was 8.3 h (median [Md] = 3.5; SD = 13.5; interquartile range [IQR] = 1.9-6.0, range = 0.8-67.4, and 90% collected within 19 h). A sample of 40 orthopedically-injured trauma control subjects recruited from a second ED also were examined. Serum NF-L levels were measured and analyzed using Human Neurology 4-Plex A assay on a HD-1 Single Molecule Array (Simoa) instrument. A high correlation was found between age and NF-L levels in the total mTBI sample (r = 0.80), within the subgroups without pre-injury neurological diseases (r = 0.76) and with pre-injury neurological diseases (r = 0.68), and in the trauma control subjects (r = 0.76). Those with mTBIs and pre-injury neurological conditions had higher NF-L levels than those with no pre-injury neurological conditions (p < 0.001, Cohen's d = 1.01). Older age and pre-injury neurological diseases are associated with elevated serum NF-L levels in patients with head trauma and in orthopedically-injured control subjects