35 research outputs found
T-cell Subsets and Antifungal Host Defenses
- Author
- A Luca De
- A Luong
- A Rivera
- A Rivera
- AJ Mednick
- B Grimbacher
- C Montagnoli
- D Fenoglio
- DA Vignali
- DM Lindell
- DN Kroetz
- DW Beno
- E Balish
- E Cenci
- E Cenci
- F McAllister
- FL Wormley Jr
- Frank L. van de Veerdonk
- FV Loures
- GH Chen
- H Hebart
- J Jones-Carson
- JE Leigh
- L McKinley
- L Romani
- L Romani
- LA Gildea
- LY Chai
- M Marquis
- M Scheckelhoff
- MA Kleinschek
- ME Munk
- MG Netea
- MG Netea
- Mihai G. Netea
- MK Mannoor
- N Haraguchi
- R Kaposzta
- RP Sutmuller
- S Bozza
- S Bozza
- T Zelante
- TR Mosmann
- W Huang
- W Stenzel
- XL Rudner
- Y Hernandez
- Y Zhang
- Publication venue
- Current Science Inc.
- Publication date
- 01/01/2010
- Field of study
It has been long appreciated that protective immunity against fungal pathogens is dependent on activation of cellular adaptive immune responses represented by T lymphocytes. The T-helper (Th)1/Th2 paradigm has proven to be essential for the understanding of protective adaptive host responses. Studies that have examined the significance of regulatory T cells in fungal infection, and the recent discovery of a new T-helper subset called Th17 have provided crucial information for understanding the complementary roles played by the various T-helper lymphocytes in systemic versus mucosal antifungal host defense. This review provides an overview of the role of the various T-cell subsets during fungal infections and the reciprocal regulation between the T-cell subsets contributing to the tailored host response against fungal pathogens
Clinical and Virological Study of Dengue Cases and the Members of Their Households: The Multinational DENFRAME Project
- Author
- A Chuansumrit
- A Sakuntabhai
- A Torrentes-Carvalho
- Aba Diop
- AC Morrison
- AC Morrison
- Anavaj Sakuntabhai
- B Murgue
- BL Innis
- Cao Minh Thang
- CG Beckett
- D Hommel
- DJ Gubler
- DM Watts
- Eva Harris
- G Teixeira Mda
- J De Benedictis
- JB Meynard
- Jean-Baptiste Meynard
- JS Mackenzie
- K Pengsaa
- L Thomas
- Laure Petit
- Laurence Baril
- LK Silva
- LoĂŻc Chartier
- Luong Chan Quang
- Lydie Beniguel
- M Reyes
- Marcio Roberto Teixeira Nunes
- MF Oliveira
- MG Guzman
- MG Guzman
- Michael Jacobs
- MP Mammen
- MR Nunes
- Ong Sivuth
- P Dussart
- P Dussart
- PC Neves-Souza
- Pedro Fernando da Costa Vasconcelos
- Philippe Buchy
- Philippe Dussart
- PR Young
- PY Shu
- PY Shu
- R Lima Mda
- R Rico-Hesse
- Raimunda do Socorro Silva Azevedo
- RS Lanciotti
- RZ Capeding
- S Alcon
- S Greenland
- S Kalayanarooj
- SB Halstead
- SD Blacksell
- Sirenda Vong
- SJ Balsitis
- SN Hammond
- Sowath Ly
- SS Twiddy
- ST Stoddard
- T Hase
- TN Chau
- TP Endy
- TP Endy
- TT Vu
- V Tricou
- Veasna Duong
- Vu Ti Que Huong
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Dengue is the most important mosquito-borne viral disease in humans. This disease is now endemic in more than 100 countries and threatens more than 2.5 billion people living in tropical countries. It currently affects about 50 to 100 million people each year. It causes a wide range of symptoms, from an inapparent to mild dengue fever, to severe forms, including dengue hemorrhagic fever. Currently no specific vaccine or antiviral drugs are available. We carried out a prospective clinical study in South-East Asia and Latin America, of virologically confirmed dengue-infected patients attending the hospital, and members of their households. Among 215 febrile dengue subjects, 177 agreed to household investigation. Based on our data, we estimated the proportion of dengue-infected household members to be about 45%. At the time of the home visit, almost three quarters of (29/39) presented an inapparent dengue infection. The proportion of inapparent dengue infection was higher in South-East Asia than in Latin America. These findings confirm the complexity of dengue disease in humans and the need to strengthen multidisciplinary research efforts to improve our understanding of virus transmission and host responses to dengue virus in various human populations
Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry
- Author
- A. L. R. Ng
- Abardia Oliva F. J.
- Abdel Malak S.
- Abdel Wahab H.
- Abdul Kareem B. B.
- Abdul Manap H.
- Abdul Rahim A. A.
- Abdulkader F.
- Abdulla A. H. K.
- AbdulWahab M. Z.
- Abduvalieva V.
- Abele S.
- Aboyans V.
- Abreu P. E.
- Adam-Blanpain M.
- Adamaszek K.
- Adamczyk-Kot D.
- Adamkiewicz-Piejko A.
- Adda M.
- Aftab A.
- Agrawal A.
- Aguiar C.
- Ahuad Guerrero A.
- Ahuja R.
- Ai F.
- Aimouch N.
- Aiyegbayo O.
- Ajani A.
- Akbar M.
- Aksyutina N.
- Al Dhanki M.
- Al Ghool S.
- Al Kandari F.
- Al Lawati A.
- Al Mahmeed W.
- Al Radaideh G.
- Al Rashdan I.
- Al Sousi A.
- Al Suwaidi J.
- Al Tamimi F.
- Al Wahshi Y.
- Al Yazeedi J.
- Al Zaibag M.
- Al-Baker H.
- Al-Faleh H.
- Al-Hersi A.
- Al-Khalidi B.
- Al-Shamiri M.
- Al-Zaibag M.
- Alam A.
- Alanazy M.
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- Albero Martinez V.
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- Alvarez Aunon A.
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- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2015
- Field of study
International Consensus Statement on Rhinology and Allergy: Rhinosinusitis
- Author
- Aanaes K
- Abadie WM
- Abi Najm S
- Abigail P
- Abrahams JJ
- Abrass LJ
- Abreu CB
- Abreu NA
- Abshirini H
- Abuzeid WM
- Abuzeid WM
- Achar P
- Ackerhans M
- Adam P
- Adappa ND
- Adappa ND
- Adappa ND
- Adappa ND
- Adriaensen G
- Agache I
- Aghamohammadi A
- Agius AM
- Agyeman AA
- Ahn CN
- Ahn HJ
- Ahn JC
- Ahn SH
- AhovuoâSaloranta A
- Aitken M
- Ajaiyeoba A
- Akbari E
- Akdis CA
- Akira S
- Akiyama K
- Akiyama K
- Akiyama K
- Al Komser MK
- Alam ES
- Alandejani T
- Alanin MC
- Albritton FDT
- Albu S
- Albu S
- Albu S
- Aldini G
- Alexander NS
- Aljebab F
- Alkire BC
- Allen EK
- Alobid I
- Alobid I
- Alobid I
- Aloulah M
- Alqudah M
- Alromaih S
- Alsaleh S
- Alsharif S
- Alt JA
- Alt JA
- Alt JA
- Alt JA
- Alt JA
- Alves MP
- AlâQudah M
- AlâQudah M.
- AlâQudah M.
- AlâRawi MM
- AlâShaikh S
- AlâShemari H
- AlâSwiahb JN
- Amali A
- Amar YG
- Amble FR
- American Academy of Pediatrics Steering Committee on Quality Improvement and Management (AAP SCQIM)
- Amin MR
- Amine M
- Amodu EJ
- Anamika A
- Anand V
- Anderson DE
- Anderson WC
- Andhale S
- Ankichetty SP
- Annamalai S
- Anon JB
- AnselmoâLima WT
- Antisdel JL
- Antisdel JL
- Antunes MB
- Antunes MB
- Anushiravani M
- Anzai Y
- AnziÄ SA
- Aramani A
- Arden KE
- Arild Danielsen K
- Aring AM
- Arjomandi H
- Armenaka M
- Arnstead N
- Arslan H
- Arslan HH
- Asaka D
- Asero R
- Asero R
- Atighechi S
- Atlas SJ
- Au J
- Aukema AA
- Aurora R
- Autio TJ
- Autio TJ
- Autio TJ
- Autio TJ
- Avdeeva K
- Awad OG
- Awad OGA
- Ayers CM
- Ayoub N
- Ayoub N
- Ayoub N
- Azbell C
- Azila A
- Baba S
- Baba S
- Baba S
- Babela R
- Babinski D
- Bachert C
- Bachert C
- Bachert C
- Bachert C
- Bachert C
- Bachert C
- Bachert C
- Bachert C
- Bachert C
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- Bachmann G
- Badia L
- Bae JS
- Bagheri SHR
- Baguley C
- Baguley CJ
- Bahtouee M
- Baker TW
- Bakhshaee M
- Balikci HH
- Balikci HH
- Balk EM
- Bang YJ
- Banhiran W
- Banks C
- Banks CA
- Banoub RG
- Baraniuk JN
- Barham HP
- Barham HP
- Barham HP
- Barham HP
- Baroody FM
- Basharat U
- Bassiouni A
- Bassiouni A
- Bassiouni A
- Batikhan H
- Batra PS
- Batra PS
- Batra PS
- Baudoin T
- Baumann A
- Bayonne E
- Becker SS
- Bednarski KA
- Behan L
- Belcher R
- Bendouah Z
- Bengtsson C
- Benjamin MR
- Benninger MS
- Benninger MS
- Benninger MS
- Benninger MS
- Benninger MS
- Benninger MS
- Benoit M
- Bent JP
- Bento LR
- BenĂtez P
- Berg O
- Berger G
- Bergeron M
- BergesâGimeno MP
- Berjis N
- Berlucchi M
- BermudezâBrito M
- Bernstein JA
- Bernstein JE
- Bernstein JM
- Berry J
- Beswick DM
- Beswick DM
- Beswick DM
- Beswick DM
- Bettadahalli V
- Beule AG
- Beyea JA
- Bezerra T
- Bezerra TF
- Bhalla RK
- Bhalla V
- Bhandarkar ND
- Bhandarkar ND
- Bhandarkar ND
- Bhatt JM
- Bhattacharjee S
- Bhattacharyya N
- Bhattacharyya N
- Bhattacharyya N
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- Bhattacharyya N
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- Bhattacharyya N
- Bhattacharyya N
- Bhattacharyya N.
- Bhattacharyya N.
- Bhawana G
- Bidder T
- Biedlingmaier JF
- Biedlingmaier JF
- Biedlingmaier JF.
- Biel MA
- Biel MA
- Bikhazi N
- Bikhazi N
- Bilge T
- Biswas K
- Biswas K
- Biswas K
- Bizaki AJ
- Blackwell DL
- Blackwell KE
- Blair C
- Bleier BS
- Bleier BS
- Bleier BS
- Bleier BS
- Blount A
- Boase S
- Boase S
- BockmĂŒhl U
- Boezaart AP
- Bohman A
- Bohman A
- Bohnhorst I
- Boita MM
- Bolger WE
- Bolger WE
- Bolger WE
- Bomeli SR
- Bondioni MP
- Bonfils P
- Bonfils P
- Bonfils P
- Bonnomet A
- Boonmak P
- Borish L
- Borsetto D
- Bosse Y
- Bosso JV
- Bothra R
- Bousquet J
- Bousquet J
- Brandsted R
- Braun JJ
- Braun JJ
- Braunstahl GJ
- Braverman I
- Brescia G
- Brescia G
- Brietzke SE
- Brietzke SE
- Brodner D
- Brook I
- Brook I
- Brook I
- Brook I
- Brook I.
- Brook I.
- BrossâSoriano D
- Brot C
- Brown CL
- Brown S
- Brozek JL
- Brozek JL
- Brumund KT
- Brunner JP
- Buckley CE
- Buehring I
- Bugten V
- BukowyâBieryllo Z
- Burgstaller JM
- Burton BN
- Bush A
- Businco LD
- Buysschaert ID
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- Yao Y
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- Yayik AM
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- Zheng C
- Zheng Z
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- Zia S
- Ziegler CGK
- ZielinskaâBlizniewska H
- Zou L
- Zuckerman JD
- Zurlo JJ
- Zuskin E
- Äulig J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2021
- Field of study
Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICARâRS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICARâRSâ2021 as well as updates to the original 140 topics. This executive summary consolidates the evidenceâbased findings of the document. Methods: ICARâRS presents over 180 topics in the forms of evidenceâbased reviews with recommendations (EBRRs), evidenceâbased reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICARâRSâ2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidenceâbased management algorithm is provided. Conclusion: This ICARâRSâ2021 executive summary provides a compilation of the evidenceâbased recommendations for medical and surgical treatment of the most common forms of RS
Seasonal association between ambient ozone and hospital admission for respiratory diseases in Hanoi, Vietnam
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2018
- Field of study
BackgroundMany studies have indicated the detrimental effect of ambient ozone to respiratory health in different countries. The levels of ozone in Hanoi, Vietnam are frequently above the WHO guideline but very few studies on the effects of ambient ozone on human health have been conducted in this location. This study aimed to examine the effects of ozone on hospital admission for respiratory diseases in Hanoi, by diseases, ages and seasons.MethodsHospital admissions, air pollutants and meteorological data were collected from January 2010 to June 2014. We used generalized linear models and distributed lag linear model to assess the association. In addition to full year analysis, we conducted restricted analysis of the data for two summer (from June-August) and winter (from December-February) seasons and grouped hospital admissions by diseases and ages (all ages, children 0 to 5 years and elderly >65 years). The delayed effect of ozone was assessed using lags of up to 5 days.ResultsOzone has a stronger effect on the risk of hospital admission for respiratory diseases and wheeze-associated disorders in the winter. For respiratory diseases, children were affected by ozone more than other age groups in both winter and summer. Each increase of 10 mu g/m(3) of ozone is associated with an increase of 6.2% risk of admission for respiratory disease among children in the winter and 1.2% in the summer. For wheeze-associated disorders, the elderly group seemed to be more affected by ozone in full year and winter but no significant association was found between ozone and admission for wheeze-associated diseases in any age group.ConclusionsOzone is a risk factor for respiratory admission, especially amongst children under 5 years old in Hanoi, and ozone has a stronger effect in the winter than in the summer in this city
Air pollution and risk of respiratory and cardiovascular hospitalizations in the most populous city in Vietnam
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
Air pollution has become an alarming issue in Vietnam recently; however, there was only one study so far on the effects of ambient air pollution on population health. Our study aimed to investigate the short-term effects of air pollutants including PM, NO, SO, and O on respiratory and cardiovascular hospitalizations in Ho Chi Minh City (HCMC), the largest city in Vietnam. Data on hospitalization from the two largest hospitals in HCMC and daily records of PM, NO, SO, O and meteorological data were collected from February 2004 to December 2007. A time-series regression analysis with distributed lag model was applied for data analysis. Changes in levels of NO and PM were strongly associated with hospital admissions for both respiratory and cardiovascular diseases (CVD); whereas levels of SO were only moderately associated with respiratory and CVD hospital admissions and O concentration was not associated with any of them. For a 10 ÎŒg/m increase of each air pollutant, the risk of respiratory admissions increased from 0.7% to 8% while the risk of CVD admissions increased from 0.5% to 4%. Females were found to be more sensitive than males to exposure to air pollutants in regard to respiratory diseases. In regard to CVD, females (RR, 1.04, 95% CI, 1.01-1.07) had a slightly higher risk of admissions than males (RR, 1.03, 95% CI, 1-1.06) to exposure to NO. In contrast, males (RR, 1.007, 95%CI, 1-1.01) had a higher risk of admission than females (RR, 1.004, 95%CI, 1.001-1.007) to exposure to PM. People in the age group of 5-65 year-olds had a slightly higher risk of admissions caused by air pollutants than the elderly (65+ years old) except for a significant effect of PM on the risk of cardiovascular admissions was found for the elderly only
Allele-Dependent Differences in Quorum-Sensing Dynamics Result in Variant Expression of Virulence Genes in Staphylococcus aureus
- Author
- Publication venue
- 'American Society for Microbiology'
- Publication date
- Field of study
Terahertz optical measurements of correlated motions with possible allosteric function
- Author
- A. G. Markelz
- AG Markelz
- CJ Tsai
- CL Brooks
- DE Koshland
- E Balog
- E Balog
- FG Parak
- G Acbas
- GS Edwards
- H Toncrova
- HN Motlagh
- I Bahar
- J Kröll
- J Monod
- JP Changeux
- JW Powell
- JW Powell
- K Achterhold
- K Gunasekaran
- Katherine A. Niessen
- KM Tych
- LY Zhu
- M Grossman
- M Karplus
- M Walther
- MC Rheinstadter
- Mengyang Xu
- MM Teeter
- P Petrone
- R Biehl
- R Chakkittakandy
- R Nussinov
- R Parthasarathy
- R Singh
- RE Bruccoleri
- RJ Falconer
- RM Levy
- T Globus
- T Weidlich
- TCB McLeish
- TM Korter
- TQ Luong
- TR Globus
- TW Crowe
- V Lisy
- VJ Hilser
- VJ Hilser
- YF He
- YM Xiao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Diagnostic value of bronchoscopy in patients with hematologic malignancy and pulmonary infiltrates
- Author
- A Bergeron
- A Seneviratna
- CD Salgado
- Chin Kook Rhee
- DP Dunagan
- E Ninin
- F Rossini
- G Cathomas
- GW Procop
- H Einsele
- H Park
- Hye Sun Kang
- Hye Yeon Lee
- J-H Yoo
- Ji Young Kang
- Jong Wook Lee
- JR Wingard
- K MĂŒhlethaler
- L Joos
- LY Hsu
- M Eiff Von
- M Hummel
- M Reinwald
- MJ Krowka
- ML Luong
- P Jain
- P White
- PV Murray
- R Breuer
- S Ewig
- S Nseir
- Sei Won Kim
- Seok Chan Kim
- Seung Joon Kim
- SM Coomes
- Sook Young Lee
- T Tia
- U Rao
- Young Kyoon Kim
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Numerical Analysis of Droplet Motion over a Flat Plate Due to Surface Acoustic Waves
- Author
- A Kawasaki
- A Marmur
- A Montessori
- A Riaud
- A Satoh
- A Wixforth
- A Wixforth
- AA Gubaidullin
- AA Mohamad
- AK Gunstensen
- B Moudjed
- B Sajjadi
- D Beyssen
- D Grunau
- D Haydock
- D KÓ§ster
- DH Rothman
- F Petersson
- H Antil
- H Huang
- H Liu
- HB Eral
- J Vanneste
- JM Valverde
- K Sritharan
- L Wu
- LS Jang
- LY Yeo
- M Alghane
- M Latva-Kokko
- M Latva-Kokko
- M Ovchinnikov
- M Taeibi-Rahni
- M Tsutahara
- M. Taeibi Rahni
- MC Sukop
- MK Tan
- MK Tan
- MR Swift
- NT Nguyen
- P Brunet
- P Lallemand
- P Lallemand
- PJ Westervelt
- Q Tang
- RJ Shilton
- S Leclaire
- S Leclaire
- S Leclaire
- S. A. Shams Taleghani
- S. M. Sheikholeslam Noori
- SJ Lighthill
- SKRS Sankaranarayanan
- SM Sheikholeslam Noori
- T Franke
- T Frommelt
- T Frommelt
- T Reis
- TD Luong
- WL Nyborg
- X Ding
- X He
- X Shan
- X Shan
- Y Ba
- Y Ba
- Y Uemura
- YJ Guo
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study