823 research outputs found

    Foundations in Wisconsin: A Directory [30th ed. 2011]

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    The 2011 edition of Foundations in Wisconsin marks the 30th production of the print directory and the 11th year of the online version (www.wifoundations.org). The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. Additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. While the national economic downturn has had a negative effect on Wisconsin foundations the past two years, there are some positive signs of recovery. The total number of active grantmaking foundations increased to a record high 1,324 (with 67 new foundations identified), and the total assets increased by 11% over last year to 6.2billion.However,totalgrantsfellto6.2 billion. However, total grants fell to 458 million, a 3% decrease from last year.https://epublications.marquette.edu/lib_fiw/1006/thumbnail.jp

    Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation.

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    Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated. Most concerning, however, are the associated harmful side effects, often unrecognized by consumers. Garcinia cambogia extract and Garcinia cambogia containing products are some of the most popular dietary supplements currently marketed for weight loss. Here, we report the first known case of fulminant hepatic failure associated with this dietary supplement. One active ingredient in this supplement is hydroxycitric acid, an active ingredient also found in weight-loss supplements banned by the Food and Drug Administration in 2009 for hepatotoxicity. Heightened awareness of the dangers of dietary supplements such as Garcinia cambogia is imperative to prevent hepatoxicity and potential fulminant hepatic failure in additional patients

    Foundations in Wisconsin: A Directory [31st ed. 2012]

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    The 2012 release of Foundations in Wisconsin marks the 31st edition of the print directory and the twelfth year of the online version. The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. Additional information was obtained from surveys, foundation Web sites, annual reports, and newsletters. Fortunately, Wisconsin foundations are rebounding from the recent economic downturn. While the total number of active foundations (1301) decreased slightly from 2011’s high number, 57 new foundations were identified and two key measures show positive growth. Total assets increased by 12% from last year to over 7billion,andgrantsrose77 billion, and grants rose 7% to 490 million, close to pre-recession totals. The following table illustrates the 10-year financial pattern as documented in Foundations in Wisconsin.https://epublications.marquette.edu/lib_fiw/1010/thumbnail.jp

    Using Concept Mapping to Investigate Engineering Students\u27 Global Workforce Perceptions

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    This study investigates engineering students’ global workforce perceptions as part of a larger research effort that addresses the global workforce expectation differences between industry and engineering graduates. Approximately 127 undergraduate engineers at a large university in the U.S. responded to the following question: What do you hope/expect to know upon completion of college to better prepare you to work successfully in a global engineering environment? To identify patterns in the responses, an integrative mixed-methods approach called concept mapping is utilized. The concept map visually illustrates and organizes dimensions related to student global workforce perceptions. Students also rated their confidence in attaining these skills as well as the importance of acquiring these skills. By combining the results of the concept map and constructing pattern matches with the rating data we identify gaps that may be used to inform future curriculum development in institutions of higher education

    Innate Pathways of Immune Activation in Transplantation

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    Studies of the immune mechanisms of allograft rejection have predominantly focused on the adaptive immune system that includes T cells and B cells. Recent investigations into the innate immune system, which recognizes foreign antigens through more evolutionarily primitive pathways, have demonstrated a critical role of the innate immune system in the regulation of the adaptive immune system. Innate immunity has been extensively studied in its role as the host's first-line defense against microbial pathogens; however, it is becoming increasingly recognized for its ability to also recognize host-derived molecules that result from tissue damage. The capacity of endogenous damage signals acting through the innate immune system to lower immune thresholds and promote immune recognition and rejection of transplant grafts is only beginning to be appreciated. An improved understanding of these pathways may reveal novel therapeutic targets to decrease graft alloreactivity and increase graft longevity

    Do slower life history strategies reduce sociodemographic sex differences?

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    This study examines the relations between sociodemographic sex differences and life history strategies in the populations of Mexican States. Sex differences in anatomy and behavior was measured with traits such as educational achievement, mortality, and morbidity. The data were obtained from the Instituto Nacional de Estadística y Geografía (INEGI) and sampled from thirty-one Mexican states and the Federal District (N = 32). An extension analysis was performed selecting only the sex ratio variables that had a correlation with the slow Life History factor greater than or equal to an absolute value of .25. A unit-weighted sex ratio factor was created using these variables. Across 32 Mexican states, the correlation between latent slow life history and sex ratio was .57 (p .05). These results are consistent with our hypothesis that slower life histories favor reduced sexual dimorphism in physiology and behavior among human subnational populations. The results of the study further understanding of variations in population sex differences, male-biased behaviors toward sexual equality, and the differences among subnational (regional) populations within the United States of Mexico.   DOI:10.2458/azu_jmmss_v6i1_chavarria_miner

    Ultra-pure platelet isolation from canine whole blood

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    Experimental study on the velocity limits of magnetized rotating plasmas

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    An experimental study on the physical limits of the rotation velocity of magnetized plasmas is presented. Experiments are performed in the Maryland Centrifugal Experiment (MCX) [R. F. Ellis , Phys. Plasmas 12, 055704 (2005)], a mirror magnetic field plasma rotating azimuthally. The externally applied parameters that control the plasma characteristics-applied voltage, external magnetic field, and fill pressure-are scanned across the entire available range of values. It is found that the plasma rotation velocity does not exceed the Alfven velocity, in agreement with the equilibrium requirements of magnetically confined plasmas. Measured rotation velocities are also lower than the critical ionization velocity in hydrogen, but a strict limit was not observable within MCX parametric capabilities. (c) 2008 American Institute of Physics

    The OSIRIS-REx Visible and InfraRed Spectrometer (OVIRS): Spectral Maps of the Asteroid Bennu

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    The OSIRIS-REx Visible and Infrared Spectrometer (OVIRS) is a point spectrometer covering the spectral range of 0.4 to 4.3 microns (25,000-2300 cm-1). Its primary purpose is to map the surface composition of the asteroid Bennu, the target asteroid of the OSIRIS-REx asteroid sample return mission. The information it returns will help guide the selection of the sample site. It will also provide global context for the sample and high spatial resolution spectra that can be related to spatially unresolved terrestrial observations of asteroids. It is a compact, low-mass (17.8 kg), power efficient (8.8 W average), and robust instrument with the sensitivity needed to detect a 5% spectral absorption feature on a very dark surface (3% reflectance) in the inner solar system (0.89-1.35 AU). It, in combination with the other instruments on the OSIRIS-REx Mission, will provide an unprecedented view of an asteroid's surface.Comment: 14 figures, 3 tables, Space Science Reviews, submitte

    Pluto's global surface composition through pixel-by-pixel Hapke modeling of New Horizons Ralph/LEISA data

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    On July 14th 2015, NASA's New Horizons mission gave us an unprecedented detailed view of the Pluto system. The complex compositional diversity of Pluto's encounter hemisphere was revealed by the Ralph/LEISA infrared spectrometer on board of New Horizons. We present compositional maps of Pluto defining the spatial distribution of the abundance and textural properties of the volatiles methane and nitrogen ices and non-volatiles water ice and tholin. These results are obtained by applying a pixel-by-pixel Hapke radiative transfer model to the LEISA scans. Our analysis focuses mainly on the large scale latitudinal variations of methane and nitrogen ices and aims at setting observational constraints to volatile transport models. Specifically, we find three latitudinal bands: the first, enriched in methane, extends from the pole to 55deg N, the second dominated by nitrogen, continues south to 35deg N, and the third, composed again mainly of methane, reaches 20deg N. We demonstrate that the distribution of volatiles across these surface units can be explained by differences in insolation over the past few decades. The latitudinal pattern is broken by Sputnik Planitia, a large reservoir of volatiles, with nitrogen playing the most important role. The physical properties of methane and nitrogen in this region are suggestive of the presence of a cold trap or possible volatile stratification. Furthermore our modeling results point to a possible sublimation transport of nitrogen from the northwest edge of Sputnik Planitia toward the south.Comment: 43 pages, 7 figures; accepted for publication in Icaru
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