604 research outputs found
Electron-electron interaction effects in quantum point contacts
We consider electron-electron interaction effects in quantum point contacts on the first quantization plateau, taking into account all scattering processes. We compute the low-temperature linear and nonlinear conductance, shot noise, and thermopower, by perturbation theory and a self-consistent nonperturbative method. On the conductance plateau, the low-temperature corrections are solely due to momentum-nonconserving processes that change the relative number of left- and right-moving electrons. This leads to a suppression of the conductance for increasing temperature or voltage. The size of the suppression is estimated for a realistic saddle-point potential, and is largest in the beginning of the conductance plateau. For large magnetic field, interaction effects are strongly suppressed by the Pauli principle, and hence the first spin-split conductance plateau has a much weaker interaction correction. For the nonperturbative calculations, we use a self-consistent nonequilibrium Green's function approach, which suggests that the conductance saturates at elevated temperatures. These results are consistent with many experimental observations related to the so-called 0.7 anomaly
Responses of a wetland ecosystem to the controlled introduction of invasive fish
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136368/1/fwb12900_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136368/2/fwb12900.pd
The merit of high-frequency data in portfolio allocation
This paper addresses the open debate about the usefulness of high-frequency (HF) data in large-scale portfolio allocation. Daily covariances are estimated based on HF data of the S&P 500 universe employing a blocked realized kernel estimator. We propose forecasting covariance matrices using a multi-scale spectral decomposition where volatilities, correlation eigenvalues and eigenvectors evolve on different frequencies. In an extensive out-of-sample forecasting study, we show that the proposed approach yields less risky and more diversified portfolio allocations as prevailing methods employing daily data. These performance gains hold over longer horizons than previous studies have shown
Electronic transport in inhomogeneous quantum wires
We study the transport properties of a long non-uniform quantum wire where
the electron-electron interactions and the density vary smoothly at large
length scales. We show that these inhomogeneities lead to a finite resistivity
of the wire, due to a weak violation of momentum conservation in the collisions
between electrons. Estimating the rate of change of momentum associated with
non-momentum-conserving scattering processes, we derive the expression for the
resistivity of the wire in the regime of weakly interacting electrons and find
a contribution linear in temperature for a broad range of temperatures below
the Fermi energy. By estimating the energy dissipated throughout the wire by
low-energy excitations, we then develop a different method for deriving the
resistivity of the wire, which can be combined with the bosonization formalism.
This allows us to compare our results with previous works relying on an
extension of the Tomonaga-Luttinger model to inhomogeneous systems.Comment: 18 pages, 2 figures. Invited paper for special issue of Journal of
Physics: Condensed Matter on "The 0.7 Feature and Interactions in
One-dimensional Systems
Molecular basis of FIR-mediated c-myc transcriptional control
The far upstream element (FUSE) regulatory system promotes a peak in the concentration of c-Myc during cell cycle. First, the FBP transcriptional activator binds to the FUSE DNA element upstream of the c-myc promoter. Then, FBP recruits its specific repressor (FIR), which acts as an on/off transcriptional switch. Here we describe the molecular basis of FIR recruitment, showing that the tandem RNA recognition motifs of FIR provide a platform for independent FUSE DNA and FBP protein binding and explaining the structural basis of the reversibility of the FBP-FIR interaction. We also show that the physical coupling between FBP and FIR is modulated by a flexible linker positioned sequentially to the recruiting element. Our data explain how the FUSE system precisely regulates c-myc transcription and suggest that a small change in FBP-FIR affinity leads to a substantial effect on c-Myc concentration.MRC Grant-in-aid U11757455
Subcoronary versus supracoronary aortic stenosis. an experimental evaluation
<p>Abstract</p> <p>Background</p> <p>Valvular aortic stenosis is the most common cause of left ventricular hypertrophy due to gradually increasing pressure work. As the stenosis develop the left ventricular hypertrophy may lead to congestive heart failure, increased risk of perioperative complications and also increased risk of sudden death. A functional porcine model imitating the pathophysiological nature of valvular aortic stenosis is very much sought after in order to study the geometrical and pathophysiological changes of the left ventricle, timing of surgery and also pharmacological therapy in this patient group.</p> <p>Earlier we developed a porcine model for aortic stenosis based on supracoronary aortic banding, this model may not completely imitate the pathophysiological changes that occurs when valvular aortic stenosis is present including the coronary blood flow. It would therefore be desirable to optimize this model according to the localization of the stenosis.</p> <p>Methods</p> <p>In 20 kg pigs subcoronary (n = 8), supracoronary aortic banding (n = 8) or sham operation (n = 4) was preformed via a left lateral thoracotomy. The primary endpoint was left ventricular wall thickness; secondary endpoints were heart/body weight ratio and the systolic/diastolic blood flow ratio in the left anterior descending coronary. Statistical evaluation by oneway anova and unpaired t-test.</p> <p>Results</p> <p>Sub- and supracoronary banding induce an equal degree of left ventricular hypertrophy compared with the control group. The coronary blood flow ratio was slightly but not significantly higher in the supracoronary group (ratio = 0.45) compared with the two other groups (subcoronary ratio = 0.36, control ratio = 0.34).</p> <p>Conclusions</p> <p>A human pathophysiologically compatible porcine model for valvular aortic stenosis was developed by performing subcoronary aortic banding. Sub- and supracoronary aortic banding induce an equal degree of left ventricular hypertrophy. This model may be valid for experimental investigations of aortic valve stenosis but studies of left ventricular hypertrophy can be studied equally well by graduated constriction of the ascending aorta.</p
ThermoElectric Transport Properties of a Chain of Quantum Dots with Self-Consistent Reservoirs
We introduce a model for charge and heat transport based on the
Landauer-Buttiker scattering approach. The system consists of a chain of
quantum dots, each of them being coupled to a particle reservoir. Additionally,
the left and right ends of the chain are coupled to two particle reservoirs.
All these reservoirs are independent and can be described by any of the
standard physical distributions: Maxwell-Boltzmann, Fermi-Dirac and
Bose-Einstein. In the linear response regime, and under some assumptions, we
first describe the general transport properties of the system. Then we impose
the self-consistency condition, i.e. we fix the boundary values (T_L,\mu_L) and
(T_R,mu_R), and adjust the parameters (T_i,mu_i), for i = 1,...,N, so that the
net average electric and heat currents into all the intermediate reservoirs
vanish. This condition leads to expressions for the temperature and chemical
potential profiles along the system, which turn out to be independent of the
distribution describing the reservoirs. We also determine the average electric
and heat currents flowing through the system and present some numerical
results, using random matrix theory, showing that these currents are typically
governed by Ohm and Fourier laws.Comment: Minor changes (45 pages
Cosmoglobe DR1. III. First full-sky model of polarized synchrotron emission from all WMAP and Planck LFI data
We present the first model of full-sky polarized synchrotron emission that is
derived from all WMAP and Planck LFI frequency maps. The basis of this analysis
is the set of end-to-end reprocessed Cosmoglobe Data Release 1 sky maps
presented in a companion paper, which have significantly lower instrumental
systematics than the legacy products from each experiment. We find that the
resulting polarized synchrotron amplitude map has an average noise rms of
at 30 GHz and FWHM, which is 30% lower than
the recently released BeyondPlanck model that included only LFI+WMAP Ka-V data,
and 29% lower than the WMAP K-band map alone. The mean -to- power
spectrum ratio is , with amplitudes consistent with those measured
previously by Planck and QUIJOTE. Assuming a power law model for the
synchrotron spectral energy distribution, and using the -- plot method,
we find a full-sky inverse noise-variance weighted mean of
between Cosmoglobe DR1 K-band and 30 GHz, in
good agreement with previous estimates. In summary, the novel Cosmoglobe DR1
synchrotron model is both more sensitive and systematically cleaner than
similar previous models, and it has a more complete error description that is
defined by a set of Monte Carlo posterior samples. We believe that these
products are preferable over previous Planck and WMAP products for all
synchrotron-related scientific applications, including simulation, forecasting
and component separation.Comment: 15 pages, 15 figures, submitted to A&
Cosmoglobe: Towards end-to-end CMB cosmological parameter estimation without likelihood approximations
We implement support for a cosmological parameter estimation algorithm as
proposed by Racine et al. (2016) in Commander, and quantify its computational
efficiency and cost. For a semi-realistic simulation similar to Planck LFI 70
GHz, we find that the computational cost of producing one single sample is
about 60 CPU-hours and that the typical Markov chain correlation length is
100 samples. The net effective cost per independent sample is 6 000
CPU-hours, in comparison with all low-level processing costs of 812 CPU-hours
for Planck LFI and WMAP in Cosmoglobe Data Release 1. Thus, although
technically possible to run already in its current state, future work should
aim to reduce the effective cost per independent sample by at least one order
of magnitude to avoid excessive runtimes, for instance through multi-grid
preconditioners and/or derivative-based Markov chain sampling schemes. This
work demonstrates the computational feasibility of true Bayesian cosmological
parameter estimation with end-to-end error propagation for high-precision CMB
experiments without likelihood approximations, but it also highlights the need
for additional optimizations before it is ready for full production-level
analysis.Comment: 10 pages, 8 figures. Submitted to A&
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