140 research outputs found

    Diagnostic Procedure for Inter-Sector Relationships in the Model of Municipal Development

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    Several methods were applied to design a new diagnostic procedure of inter-sector relationships, and the coordination between development strategies and key economic sectors within the strategic planning system in the municipality of Nuevitas, province of Camaguey, Cuba. The methods included analysis-synthesis; systemic, to conceive the character of component relationships; interview, survey, and documentary research. They made possible the characterization of the current situation in the municipality. The diagnostic revealed that the analysis of inter-sector relationships is not usually made, due to ongoing deficiencies regarding a procedure design to perform situational strategic diagnostics. According to the results achieved, insufficiencies in inter-sector relationships among the institutions selected for the study were identified, as a reflection of the poor coordination among the sectors. Potentialities and restrictions, weaknesses, strengths, and opportunities were revealed, which called for the implementation of a diagnostic of inter-sector relationships in the area of development strategies. The methodological proposal rests on the supposition that diagnostics should establish methods to include analysis of horizontal relationships among the sectors, convergence with the local development strategy, and more efficiency of integrated development programs.                Several methods were applied to design a new diagnostic procedure of inter-sector relationships, and the coordination between development strategies and key economic sectors within the strategic planning system in the municipality of Nuevitas, province of Camaguey, Cuba. The methods included analysis-synthesis; systemic, to conceive the character of component relationships; interview, survey, and documentary research. They made possible the characterization of the current situation in the municipality. The diagnostic revealed that the analysis of inter-sector relationships is not usually made, due to ongoing deficiencies regarding a procedure design to perform situational strategic diagnostics. According to the results achieved, insufficiencies in inter-sector relationships among the institutions selected for the study were identified, as a reflection of the poor coordination among the sectors. Potentialities and restrictions, weaknesses, strengths, and opportunities were revealed, which called for the implementation of a diagnostic of inter-sector relationships in the area of development strategies. The methodological proposal rests on the supposition that diagnostics should establish methods to include analysis of horizontal relationships among the sectors, convergence with the local development strategy, and more efficiency of integrated development programs.               &nbsp

    Towards sustainable industrial development - a systems thinking-based approach

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    Various critical global issues, including global warming and poverty, have been recognized and identified by the United Nations (UN) as drivers for unsustainability. Consequently, the UN established the Sustainable Development Goals (SDGs) with the aim of seeking universal peace and larger freedom by balancing the three dimensions of sustainable development, i.e. economic, social and environmental. A particular attention SDGs pay is in eradicating poverty as this is considered one of the greatest global challenges. Poverty is not only an economic matter as it also has an impact on the social and environmental dimensions. A strategy to tackle poverty is to foster industry development. However, a holistic point of view is necessary by also considering stakeholders otherwise, it becomes a neoliberal solution. Despite the fact that some research has been conducted, e.g. case studies and surveys of sustainable practices, there is a lack of industrial sustainable development as a framework to tackle sustainability issues. Thus, this paper proposes a framework for industrial sustainable development under a socially inclusive approach within the context of the Mexican manufacturing industry. The framework proposal is based on a state-of-the-art literature review conducted in the Web of Science and Scopus databases.N/

    MĂ©todo para el diagnĂłstico de las relaciones intersectoriales en el modelo de desarrollo municipal

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    Con el  objetivo de diseñar un mĂ©todo que permita el diagnĂłstico de las relaciones intersectoriales, y la coordinaciĂłn entre las estrategias de desarrollo, y los sectores claves de la economĂ­a  en el sistema de gestiĂłn estratĂ©gica  del municipio de Nuevitas, provincia de CamagĂĽey, se utilizaron los mĂ©todos de análisis, sĂ­ntesis, el sistĂ©mico  para concebir el carácter de las interacciones entre sus componentes, las entrevistas, encuestas,  y el análisis documental, los que posibilitaron caracterizar la situaciĂłn actual del municipio. Se develĂł en el diagnĂłstico que no se introduce el análisis de las relaciones intersectoriales, lo cual se encuentra influenciado, por las deficiencias que aĂşn existen en cuanto al diseño de la metodologĂ­a para el diagnĂłstico estratĂ©gico situacional. De acuerdo a los resultados obtenidos, se identificaron las insuficiencias existentes en cuanto al estado de las relaciones intersectoriales en las entidades seleccionadas, lo cual manifiesta  una deficiente coordinaciĂłn entre los diferentes sectores, evidenciando las  potencialidades y restricciones, debilidades y amenazas, fortalezas y oportunidades que existen en el municipio, siendo necesario se elabore en el diagnĂłstico la problemática que afecta las relaciones intersectoriales en las estrategias de desarrollo. La propuesta metodolĂłgica para el diagnĂłstico tiene como principales supuestos, que los diagnĂłsticos deben establecer mĂ©todos para incluir el análisis de las relaciones horizontales entre los diferentes sectores, hacia el logro de la convergencia con la estrategia de desarrollo en el municipio y una mayor eficiencia en los programas de desarrollo integral.  &nbsp

    Comments on gluon scattering amplitudes via AdS/CFT

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    In this article we consider n gluon color ordered, planar amplitudes in N=4 super Yang Mills at strong 't Hooft coupling. These amplitudes are approximated by classical surfaces in AdS_5 space. We compute the value of the amplitude for a particular kinematic configuration for a large number of gluons and find that the result disagrees with a recent guess for the exact value of the amplitude. Our results are still compatible with a possible relation between amplitudes and Wilson loops. In addition, we also give a prescription for computing processes involving local operators and asymptotic states with a fixed number of gluons. As a byproduct, we also obtain a string theory prescription for computing the dual of the ordinary Wilson loop, Tr P exp[ i\oint A ], with no couplings to the scalars. We also evaluate the quark-antiquark potential at two loops.Comment: 27 pages, 9 figures,v3:minor correction

    Diagnostic Procedure for Inter-Sector Relationships in the Model of Municipal Development

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    Several methods were applied to design a new diagnostic procedure of inter-sector relationships, and the coordination between development strategies and key economic sectors within the strategic planning system in the municipality of Nuevitas, province of Camaguey, Cuba. The methods included analysis-synthesis; systemic, to conceive the character of component relationships; interview, survey, and documentary research. They made possible the characterization of the current situation in the municipality. The diagnostic revealed that the analysis of inter-sector relationships is not usually made, due to ongoing deficiencies regarding a procedure design to perform situational strategic diagnostics. According to the results achieved, insufficiencies in inter-sector relationships among the institutions selected for the study were identified, as a reflection of the poor coordination among the sectors. Potentialities and restrictions, weaknesses, strengths, and opportunities were revealed, which called for the implementation of a diagnostic of inter-sector relationships in the area of development strategies. The methodological proposal rests on the supposition that diagnostics should establish methods to include analysis of horizontal relationships among the sectors, convergence with the local development strategy, and more efficiency of integrated development programs

    Fostering economic growth, social inclusion & sustainability in Industry 4.0: a systemic approach

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    The most modern and mature industrial manufacturing revolution is known as Industry 4.0 (I4.0). Technological advance seeks to minimize all sorts of waste, optimizing the firm's performance operations aligning this its competitive advantage. While in developing economies often overlooked the society and environment under the current neoliberalism strategy, whose competitive approach is enforced by the State, with a detriment of local SMEs such as Mexico. Thereby, to lead I4.0 implementation for SMEs, the role of the State for a long-term strategic approach is of utmost importance. The industrial strategy should regard the imminent industrial revolution without leaving behind environmental and social dimensions to implement it, like the Scandinavian economies example. This research proposes the soft systems methodology for dealing with the sustainable complexity context and inclusive industrial development phenomena. Its holistic nature provides useful insights that devise how I4.0 and social inclusion fit into the Mexican context. The theoretical proposal builds upon the social inclusion state-of-the-art in the industry 4.0 and a survey for an affordable I4.0 initiative through a stakeholder system's network communication approach. The inclusive strategy is an effort to align root systems for sustainable development with stakeholders for Mexican SMEs in the manufacturing sector

    Influence of IL28B Polymorphisms on Response to a Lower-Than-Standard Dose peg-IFN-α 2a for Genotype 3 Chronic Hepatitis C in HIV-Coinfected Patients

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    Background: Data on which to base definitive recommendations on the doses and duration of therapy for genotype 3 HCV/HIV-coinfected patients are scarce. We evaluated the efficacy of a lower peginterferon-α 2a dose and a shorter duration of therapy than the current standard of care in genotype 3 HCV/HIV-coinfected patients. Methods and Findings: Pilot, open-label, single arm clinical trial which involved 58 Caucasian HCV/HIV-coinfected patients who received weekly 135 μg peginterferon-α 2a plus ribavirin 400 mg twice daily during 20 weeks after attaining undetectable viremia. The relationships between baseline patient-related variables, including IL28B genotype, plasma HCV-RNA, ribavirin dose/kg, peginterferon-α 2a and ribavirin levels with virological responses were analyzed. Only 4 patients showed lack of response and 5 patients dropped out due to adverse events related to the study medication. Overall, sustained virologic response (SVR) rates were 58.3% by intention-to-treat and 71.4% by per protocol analysis, respectively. Among patients with rapid virologic response (RVR), SVR and relapses rates were 92.6% and 7.4%, respectively. No relationships were observed between viral responses and ribavirin dose/kg, peginterferon-α 2a concentrations, ribavirin levels or rs129679860 genotype. Conclusions: Weekly 135 μg pegIFN-α 2a could be as effective as the standard 180 μg dose, with a very low incidence of severe adverse events. A 24-week treatment duration appears to be appropriate in patients achieving RVR, but extending treatment up to just 20 weeks beyond negativization of viremia is associated with a high relapse rate in those patients not achieving RVR. There was no influence of IL28B genotype on the virological responses. © 2012 López-Cortés et al.Funding provided by Fundación Pública Andaluza para la gestión de la Investigación en Salud de Sevilla. Hospitales Universitarios Virgen del Rocío. Seville, Spain. The enzyme-linked immunosorbent assay Hu-INF-α kits for determination of pegIFN-α-2a were financed by Roche Pharma, S.A. (Spain).Peer Reviewe

    Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand.

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    OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand. METHODS: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters. RESULTS: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean. CONCLUSION: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age
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