18 research outputs found

    Responsabilidades universitarias : Reflexiones desde una experiencia de extensión con jóvenes en contextos de encierro

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    El presente trabajo es una reflexión sobre la experiencia del proyecto de extensión universitaria “Contraseña: promoción de derechos desde la comunicación”, en el que se realizan talleres de comunicación y derechos humanos con jóvenes en contextos de encierro. La práctica de tres años continuados nos ha llevado a repensar la extensión universitaria; ya no como una herramienta para que la Universidad transmita conocimientos a lugares y/o personas que “no los tienen”, sino como espacio de construcción de conocimiento colectivo que habilite a pensar entonces otra universidad posible.Eje temático: Universidad y extensiónFacultad de Periodismo y Comunicación Socia

    Responsabilidades universitarias : Reflexiones desde una experiencia de extensión con jóvenes en contextos de encierro

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    El presente trabajo es una reflexión sobre la experiencia del proyecto de extensión universitaria “Contraseña: promoción de derechos desde la comunicación”, en el que se realizan talleres de comunicación y derechos humanos con jóvenes en contextos de encierro. La práctica de tres años continuados nos ha llevado a repensar la extensión universitaria; ya no como una herramienta para que la Universidad transmita conocimientos a lugares y/o personas que “no los tienen”, sino como espacio de construcción de conocimiento colectivo que habilite a pensar entonces otra universidad posible.Eje temático: Universidad y extensiónFacultad de Periodismo y Comunicación Socia

    Responsabilidades universitarias : Reflexiones desde una experiencia de extensión con jóvenes en contextos de encierro

    Get PDF
    El presente trabajo es una reflexión sobre la experiencia del proyecto de extensión universitaria “Contraseña: promoción de derechos desde la comunicación”, en el que se realizan talleres de comunicación y derechos humanos con jóvenes en contextos de encierro. La práctica de tres años continuados nos ha llevado a repensar la extensión universitaria; ya no como una herramienta para que la Universidad transmita conocimientos a lugares y/o personas que “no los tienen”, sino como espacio de construcción de conocimiento colectivo que habilite a pensar entonces otra universidad posible.Eje temático: Universidad y extensiónFacultad de Periodismo y Comunicación Socia

    ebola virus disease case management in the institute of infectious diseases university hospital of sassari sardinia italy

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    Since the onset of the worst epidemic of Ebola virus disease in December 2013, 28,637 cases were reported as confirmed, probable, or suspected. Since the week of 3 January 2016, no more cases have been reported. The total number of deaths have amounted to 11,315 (39.5%). In developed countries, seven cases have been diagnosed: four in the United States, one in Spain, one in the United Kingdom, and one in Italy. On 20 July 2015, Italy was declared Ebola-free. On 9 May 2015, an Italian health worker came back to Italy after a long stay in Sierra Leone working for a non-governmental organization. Forty-eight hours after his arrival, he noticed headache, weakness, muscle pains, and slight fever. The following day, he was safely transported to the Infectious Diseases Unit of University Hospital of Sassari. The patient was hospitalized for 19 hours until an Italian Air Force medical division transferred him to Rome, to the Lazzaro Spallanzani Institute. Nineteen people who had contacts with the patient were monitored daily for 21 days by the Public Health Office of Sassari and none presented any symptoms. So far, neither vaccine nor treatment is available to be proposed on an international scale. Ebola is considered a re-emerging infectious disease which, unlike in the past, has been a worldwide emergency. This case study aimed to establish a discussion about the operative and logistic difficulties to be faced and about the discrepancy arising when protocols clash with the reality of facts

    Seismic scattering attribute for sedimentary classification of nearshore marine quarries for a major beach nourishment project: Case study of Adriatic coastline, Regione Abruzzo (Italy)

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    Of fundamental importance for any major beach nourishment project using marine quarries is a correct sedimentary classification. The main purpose of such a classification is to identify sand with the appropriate features for beach nourishment. This task is more onerous when quarry sediments are heterogeneous and mixed with silt. This is typical of nearshore marine quarries. The presence of excess silt compromises the use of marine quarries because of the water turbidity that may be induced in the nourished beaches, especially when the beaches are protected by defense structures. Here we discuss the use of scattering amplitude of seismic data, acquired with a pinger source (2-10 kHz), to detect and classify the unconsolidated sediment of a marine quarry. A robust correlation was found between this seismic attribute and the silt content in the sediment. The scattering amplitude was numerically calculated from the seismic data and used to map slices of silt content at different depths. The results have been validated with sedimentary analysis of vibra- and rotary cores, and by the dredged material used for the beach nourishment. The marine quarry produced about 1.200.000 m(3) of sand used to nourish eight different beach sites along the Adriatic coasts of the Regione Abruzzo (Italy). The large-scale sedimentary assessment of the area was based on seismic boomer data and the evaluation of the volume of dredged sediments on multibeam data surveyed before and after the exploitation of the quarry. The study shows that this approach is effective in sites with high lateral and vertical variations in the percentage of sand in the sediments

    Nearshore sand mining for beach nourishment: the case study of the 2010 Abruzzo project (Italy)

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    L'articolo descrive gli studi e le analisi eseguite a supporto del primo progetto italiano di ripascimento artificiale realizzato con sabbia di cava marina posta su bassi fondali. Gli interventi di ripascimento, conclusi nel 2010, hanno riguardato tratti della costa della regione Abruzzo.The paper describes the studies carried out in order to support the first Italian artificial beach nourishment made by nearshore sand mining. The beach nourishment works, completed in 2010, has been carried out along the coast of Abruzzo Region

    Analysis of pre- and postsynaptic activity in the frog semicircular canal following ototoxic insult: differential recovery of background and evoked afferent activity.

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    11Frogs were treated with a single dose of gentamicin administered intraotically to produce severe degeneration of posterior semicircular canal hair cells and to evaluate the time course of functional damage and recovery both at pre- and postsynaptic level. In isolated canal preparations the endoampullar potential, which reflects the summed receptor potentials of crista hair cells, was progressively reduced in amplitude and completely abolished 6 days after gentamicin treatment. At this time the crista epithelium was devoid of hair cells. The recovery of the endoampullar potential began around 9 days after the ototoxic insult and its amplitude progressively increased to reach, after 20 days, values close to those observed in control experiments. The endoampullar potential amplitude was related to the degree of hair cell regeneration in the crista epithelium. Consistent with the presynaptic damage, the slow generator potential (representing the summed miniature excitatory postsynaptic potential [mEPSP] activity of all posterior nerve fibres) and the resting and evoked spike discharge recorded from the whole ampullar nerve were abolished 6 days after gentamicin treatment. The recovery of the background and evoked afferent activity showed different behaviours. Background spike activity became detectable around 8 days after the ototoxic insult, but was not modulated by canal stimulation at this time, and no generator potential was detected. Moreover, the resting spike frequency fully recovered and reached control values around 15 days after gentamicin treatment, whereas the evoked activity attained normal values only 20 days after the ototoxic insult. These results were confirmed by intracellular recordings from single afferent fibres of the ampullar nerve in intact labyrinth preparations. Absence of any resting and evoked discharge was the most common pattern observed in the early period from 7 to 8 days after gentamicin treatment. Fifty-five percent of impaled afferents were silent while the others showed low resting frequencies of mEPSPs and spikes, and were unresponsive to canal rotation. In the intermediate period from 14 to 15 days after gentamicin treatment, background mEPSP and spike frequencies approached those evaluated in control experiments, but the frequencies of the evoked mEPSPs and spikes were clearly lower than in controls. In the late period, from 18 to 20 days after the ototoxic insult, the impaled afferents showed normal evoked mEPSP and spike frequencies. The present data indicate that the frog semicircular canal completely recovers its pre- and postsynaptic activity following severe ototoxic insult. During the regeneration process, the cytoneural junction regains function and the resting discharge reappears before recovery of mechanoelectrical transduction.noneG. Russo;D. Calzi;L. Gioglio;L. Botta;M. R. Polimeni;G. Zucca;M. Martini;D. Contini;R. Fesce;M. L. Rossi;I. PrigioniG., Russo; D., Calzi; L., Gioglio; L., Botta; M. R., Polimeni; G., Zucca; M., Martini; D., Contini; Fesce, RICCARDO GIUSEPPE; M. L., Rossi; I., Prigion

    Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD Searching for an effect of allelic heterogeneity

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    Although several studies have demonstrated an association between the 7-repeat (7R) allele in the 48-bp variable number of tandem repeats (VNTRs) in the exon 3 at dopamine receptor D4 (DRD4) gene and attention-deficit/ hyperactivity disorder (ADHD), others failed to replicate this finding. In this study, a total of 786 individuals with ADHD were genotyped for DRD4 exon 3 VNTR. All 7R homozygous subjects were selected for VNTR re-sequencing. Subjects homozygous for the 4R allele were selected paired by age, ancestry and disorder subtypes in order to have a sample as homogeneous as possible with 7R/7R individuals. Using these criteria, 103 individuals (66 with ADHD and 37 control individuals) were further investigated. An excess of rare variants were observed in the 7R alleles of ADHD patient when compared with controls (P = 0.031). This difference was not observed in 4R allele. Furthermore, nucleotide changes that predict synonymous and non-synonymous substitutions were more common in the 7R sample (P = 0.008 for total substitutions and P = 0.043 for non-synonymous substitutions). In silico prediction of structural/functional alterations caused by these variants have also been observed. Our findings suggest that not only repeat length but also DNA sequence should be assessed to better understand the role of DRD4 exon 3 VNTR in ADHD genetic susceptibility.C
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