13 research outputs found

    Mineralogical and Petrographical Studies of the Yamato Meteorites, Yamato-7301(j), -7305(k), -7308(l) and -7303(m) from Antarctica

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    In 1973,the 14th Japanese Antarctic Research Expedition party collected twelve meteoritic stones in the bare ice field near the Yamato Mountains, Antarctica. Four of the stones were named Yamato-7301,-7305,-7308 and -7303. Yamato-7301,-7305 and -7303 are ordinary chondrites and are classified respectively as H4,L5 and L5 chondrites, while Yamato-7308 is a howardite. Yamato-7301,-7305 and -7303 are composed chiefly of olivine ((Fo)_) and orthopyroxene ((En)_), with subordinate amounts of clinopyroxene, plagioclase and phosphate minerals. Opaque minerals, nickel-iron, troilite and chromite, are more abundant in Yamato-7301 than in Yamato-7305 and -7303. Yamato-7308 is composed mainly of pyroxene and plagioclase (anorthite), with olivine, silica minerals, opaque minerals and glassy material in minor amounts. The composition of orthopyroxene is variable ranging from (En)_ to (En)_, and also clinopyroxene varies considerably in composition. The result suggests that Yamato-7308 originated from the fractional crystallization of the parent magma of the achondrite

    Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources

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    The Human Phenotype Ontology (HPO)-a standardized vocabulary of phenotypic abnormalities associated with 7000+ diseases-is used by thousands of researchers, clinicians, informaticians and electronic health record systems around the world. Its detailed descriptions of clinical abnormalities and computable disease definitions have made HPO the de facto standard for deep phenotyping in the field of rare disease. The HPO's interoperability with other ontologies has enabled it to be used to improve diagnostic accuracy by incorporating model organism data. It also plays a key role in the popular Exomiser tool, which identifies potential disease-causing variants from whole-exome or whole-genome sequencing data. Since the HPO was first introduced in 2008, its users have become both more numerous and more diverse. To meet these emerging needs, the project has added new content, language translations, mappings and computational tooling, as well as integrations with external community data. The HPO continues to collaborate with clinical adopters to improve specific areas of the ontology and extend standardized disease descriptions. The newly redesigned HPO website (www.human-phenotype-ontology.org) simplifies browsing terms and exploring clinical features, diseases, and human genes
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