Modelling J/psi production and absorption in a microscopic nonequilibrium approach

Charmonium production and absorption in heavy ion collisions is studied with the Ultrarelativisitic Quantum Molecular Dynamics model. We compare the scenario of universal and time independent color-octet dissociation cross sections with one of distinct color-singlet J/psi, psi' and chi_c states, evolving from small, color transparent configurations to their asymptotic sizes. The measured J/psi production cross sections in pA and AB collisions at SPS energies are consistent with both - purely hadronic - scenarios. The predicted rapidity dependence of J/psi suppression can be used to discriminate between the two experimentally. The importance of interactions with secondary hadrons and the applicability of thermal reaction kinetics to J/psi absorption are investigated. We discuss the effect of nuclear stopping and the role of leading hadrons. The dependence of the psi' to J/psi ratio on the model assumptions and the possible influence of refeeding processes is also studied.Comment: 35 pages, 16 figure

Comprehensive Characterization Of Lipids From Amazonian Vegetable Oils By Mass Spectrometry Techniques

An integrative approach in mass spectrometry (MS) comprising gas chromatography coupled to MS (GC-MS), ultra-efficiency liquid chromatography coupled to MS (UPLC-MS) and easy ambient sonic-spray ionization MS (EASI-MS) is proposed for the comprehensive characterization of Amazonian oils. Coconut, andiroba and castor seed oils, which are vastly sold in markets of the Amazonian region of Brazil, were selected as a representative test set. These oils were found to contain several lipids such as triacylglycerides (TAGs), fatty acids (FAs), phytosterols and limonoids. In the analyzed samples 30 different TAGs, 11 FAs, 6 phytosterols and 7 limonoids were identified. The antioxidant capacity (AOC) of the oils, as measured by their oxygen radical absorbance capacity (ORAC), was also used to evaluate their potential biological properties as well as their possible consumption as food. Edible virgin coconut oil was the most active (0.720. ±. 0.001 Trolox eq./mmol), whereas considerable lower activity was observed for andiroba and castor seed oils. The antimicrobial activities of the oils were also recorded against a panel of pathogenic bacteria and fungi in which andiroba oil was the only one that was active, solely against Enterococcus aeruginosa. © 2014 Elsevier Ltd.64472481Akande, T.O., Odunsi, A.A., Adedeji, O.S., Toxicity and nutritive assessment of castor oil (Ricinus communis) oil and processed cake in rate diet (2011) Asian Journal of Animal Sciences, 5, pp. 330-339Ambrozin, A.R.P., Leite, A.C., Bueno, F.C., Vieira, P.C., Fernandes, J.B., Bueno, O.C., Limonoids from andiroba oil and Cedrela fissilis and their insecticidal activity (2006) Journal of the Brazilian Chemical Society, 17, pp. 542-547Barbosa, B.S., Koolen, H.H.F., Barreto, A.C., da Silva, J.D., Figlioulo, R., Nunomura, S.M., The use of tucumã of Amazonas kernel oil in the biodiesel production (2009) Acta Amazonica, 39, pp. 371-376Breksa, A.P., Manners, G.D., Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside (2006) Journal of Agricultural and Food Chemistry, 54, pp. 3827-3831Cabral, E.C., da Cruz, G.F., Simas, R.C., Sanvido, G.B., Gonçalves, L.V., Leal, R.V.P., Typification and quality control of the andiroba (Carapa guianensis) oil via mass spectrometry fingerprinting (2013) Analytical Methods, 5, pp. 1385-1391César, A.S., Batalha, M.O., Biodiesel production from castor oil in Brazil: A difficult reality (2010) Energy Policy, 38, pp. 4031-4039Chakraborty, M., Mitra, A., The antioxidant and antimicrobial activity properties of the methanolic extract from Cocos nucifera mesocarp (2008) Food Chemistry, 107, pp. 994-999Chen, J., Wu, X., Zhang, Y., Relationship between antioxidants and acrylamide formation: A review (2013) Food Research International, 51, pp. 611-620Cherif, A.O., Leveque, N., Messaoudac, M.B., Kallel, H., Moussa, F., An electrospray ionisation-mass spectrometry screening of triacylglycerols in developing cultivated and wild peanut kernels (Arachis hypogaea L.) (2013) Food Chemistry, 138, pp. 1095-1100da Silva, V.P., Oliveira, R.R., Figueiredo, M.R., Isolation of limonoids from seeds of Carapa guianensis Aublet (Meliaceae) by high-speed countercurrent chromatography (2009) Phytochemical Analysis, 20, pp. 77-81Dávalos, A., Gómez-Cordovés, C., Bartolomé, B., Extending applicability of the oxygen radical absorbance capacity (ORAC-fluorescein) assay (2004) Journal of Agricultural and Food Chemistry, 52, pp. 48-54Dudonné, S., Vitrac, X., Coutière, P., Woillez, M., Mérillon, J.M., Comparative study of antioxidant properties and total phenolic content of 30 plant extracts of industrial interest using DPPH, ABTS, FRAP, SOD, and ORAC assays (2009) Journal of Agricultural and Food Chemistry, 57, pp. 1768-1774Funasaki, M., Oliveira, R.S., Zanotto, S.P., Carioca, C.R.F., Simas, R.C., Eberlin, M.N., Brazil nut oil: Quality control via triacylglycerol profiles provided by easy ambient sonic-spray ionization mass spectrometry (2012) Journal of Agricultural and Food Chemistry, 60, pp. 11263-11267Haddad, R., Milagres, H.M.S., Catharino, R.R., Eberlin, M.N., Easy ambient sonic-spray ionization mass spectrometry combined with thin-layer chromatography (2008) Analytical Chemistry, 80, pp. 2744-2750Hamburger, M., Riese, U., Graf, H., Melzig, M.F., Ciesielski, S., Baumann, D., Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities (2002) Journal of Agricultural and Food Chemistry, 50, pp. 5533-5538Kesena, S., Kelebek, H., Senc, K., Ulas, M., Selli, S., GC-MS-olfactometric characterization of the key aroma compounds in Turkish olive oils by application of the aroma extract dilution analysis (2013) Food Research International, 54, pp. 1987-1994Koolen, H.H.F., da Silva, F.M.A., Gozzo, F.C., de Souza, A.Q.L., de Souza, A.D.L., Antioxidant, antimicrobial activities and characterization of phenolic compounds from buriti (Mauritia flexuosa L.f.) by UPLC-ESI-MS/MS (2013) Food Research International, 51, pp. 467-473Koolen, H.H.F., Soares, E.R., da Silva, F.M.A., de Almeida, R.A., de Souza, A.D.L., de Medeiros, L.S., An antimicrobial alkaloid and other metabolites produced by Penicillium sp. An endophytic fungus isolated from Mauritia flexuosa L.f. (2012) Quimica Nova, 35, pp. 771-774Koolen, H.H.F., Soares, E.R., da Silva, F.M.A., de Souza, A.Q.L., de Medeiros, L.S., Rodrigues-Filho, E., An antimicrobial diketopiperazine alkaloid and co-metabolites from an endophytic strain of Gliocladium isolated from Strychnos cf. toxifera (2012) Natural Product Research, 26, pp. 2013-2019Lay, J.O., Linayage, R., Durham, B., Brooks, J., Rapid characterization of edible oils by direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis using triacylglycerols (2006) Rapid Communications in Mass Spectrometry, 20, pp. 952-958Lemire, M., Fillion, M., Barbosa-Júnior, F.B., Guimarães, J.R.D., Mergler, D., Elevated levels of selenium in the typical diet of Amazonian riverside populations (2010) Science of the Total Environment, 408, pp. 4076-4084Liu, C., Li, J., Lei, W., Zhou, Y., Development of biobased unsaturated polyester resin containing highly functionalized castor oil (2014) Industrial Crops and Products, 52, pp. 329-337Marina, A.M., Man, Y.B.C., Ismail, A., Virgin coconut oil: Emerging functional food oil (2009) Trends in Food Science and Technology, 20, pp. 481-487Marina, A.M., Man, Y.B.C., Nazimah, S.A.H., Amin, I., Antioxidant capacity and phenolic acids of virgin coconut oil (2009) International Journal of Food Sciences and Nutrition, 60, pp. 114-123Mendonça, F.A.C., Silva, K.F.S., Santos, K.K., Ribeiro-Júnior, K.A.L., Activities of some Brazilian plants against larvae of the mosquito Aedes aegypti (2005) Fitoterapia, 76, pp. 629-636. , Sant'AnaMiranda-Júnior, R.N.C., Dolabela, M.F., da Silva, M.N., Póvoa, M.M., Maia, J.G.S., Antiplasmodial activity of the andiroba (Carapa guianensis Aubl., Meliaceae) oil and its limonoid-rich fraction (2012) Journal of Ethnopharmacology, 142, pp. 679-683Nazif, N.M., Phytoconstituents of Zizyphus spina-christi L. fruits and their antimicrobial activity (2002) Food Chemistry, 76, pp. 77-81Oliveira, J.F.G., Lucena, I.L., Saboya, R.M.A., Rodrigues, M.L., Torres, A.E.B., Fernandes, F.A.N., Biodiesel production from waste coconut oil by esterification with ethanol: The effect of water removal by adsorption (2010) Renewable Energy, 35, pp. 2581-2584Ollis, W.D., Ward, A.D., de Oliveira, H.M., Zelnik, R., Andirobin (1970) Tetrahedron, 26, pp. 1637-1645Oloyede, G.K., Antioxidant activities of methyl ricinoleate and ricinoleic acid dominated Ricinus communis seeds extract using lipid peroxidation and free radical scavenging methods (2012) Journal of Medicinal Plant, 6, pp. 511-520Pérez-Jímenez, J., Arranz, S., Tabernero, M., Díaz-Rúbio, M.E., Serrano, J., Goñi, I., Updated methodology to determine antioxidant capacity in plant foods, oils and beverages: Extraction, measurement and expression of results (2008) Food Research International, 41, pp. 274-285Pesce, C., (1985) Oil palms and other oilseeds of the Amazon, pp. 61-151. , Johnson, D. V., Algonac, MIPoulose, S.M., Harris, E.D., Patil, B.S., Citrus limonoids induce apoptosis in human neuroblastoma cells and have radical scavenging activity (2005) Journal of Nutrition, 135, pp. 870-877Prior, R.L., Wu, X., Schaich, K., Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements (2005) Journal of Agricultural and Food Chemistry, 53, pp. 4290-4302Qi, S.H., Wu, D.G., Zhang, S., Luo, X.D., Constituents of Carapa guianensis Aubl. (Meliaceae) (2004) Pharmazie, 59, pp. 488-490Roginsky, V., Lissi, E.A., Review of methods to determine chain-breaking antioxidant activity in food (2005) Food Chemistry, 92, pp. 235-254Roma, G.C., Vendramini, M.C.R., Mathias-Camargo, M.I., Nunes, P.H., de Faria, A.U., Bechara, G.H., Action of andiroba oil and permethrin on the central nervous and reproductive systems of Rhipicephalus sanguineu (Latreille, 1806) (Acari: Ixodidae) ticks females. A confocal study (2013) Research in Veterinary Science, 95, pp. 529-536Rostad, C.E., Pereira, W.E., Kovats and Lee retention indices determined by gas chromatography/mass spectrometry for organic compounds of environmental interest (1986) Journal of High Resolution Chromatography & Chromatography Communications, 9, pp. 328-334Salvador, M.J., Ferreira, E.O., Pral, E.M.F., Alfieri, S.C., Albuquerque, S., Ito, I.Y., Bioactivity of crude extracts and some constituents of Blutaparon portulacoides (Amaranthaceae) (2002) Phytomedicine, 9, pp. 566-571Santos, R.C.V., Alves, C.F.S., Schneider, T., Lopes, L.Q.S., Aurich, C., Giongo, J.L., Brandelli, A., Vaucher, R.A., Antimicrobial activity of Amazonian oils against Paenibacillus species (2012) Journal of Invertebrate Pathology, 109, pp. 265-268Saraiva, S.A., Cabral, E.C., Eberlin, M.N., Catharino, R.R., Amazonian vegetable oils and fats: Fast typification and quality control via triacylglycerol (TAG) profiles from dry matrix-assisted laser desorption/ionization (MALDI-TOF) mass spectrometry fingerprinting (2009) Journal of Agricultural and Food Chemistry, 57, pp. 4030-4034Shoba, F.G., Thomas, M., Study of antidiarrhoeal activity of four medicinal plants in castor oil-induced diarrhea (2001) Journal of Ethnophacology, 76, pp. 73-76Silva, S.G., Nunomura, R.S., Nunomura, S.M., Limonóides isolados dos frutos de Carapa guianensis Aublet (Meliaceae) (2012) Quimica Nova, 35, pp. 1936-1939Silva, V.P., Oliveira, R.R., Figueiredo, M.R., Isolation of limonoids from seeds of Carapa guianenses Aublet. (Meliaceae) by high-speed counter current chromatography (2009) Phytochemical Analysis, 20, pp. 77-81Solis, M.I.V., Patel, A., Orsat, V., Singhb, J., Lefsruda, M., Fatty acid profiling of the seed oils of some varieties of field peas (Pisum sativum) by RP-LC/ESI-MS/MS: Towards the development of an oilseed pea (2013) Food Chemistry, 139, pp. 986-993Souza, J.N.S., Silva, E.M., Loiir, A., Rees, J.F., Rogez, H., Larondelle, Y., Antioxidant capacity of four polyphenol-rich Amazonian plant extracts: A correlation study using chemical and biological in vitro assays (2008) Food Chemistry, 106, pp. 331-339Sun, C., Chen, K., Chen, Y., Chen, Q., Contents and antioxidant capacity of limonin and nomilin in different tissues of citrus fruit of four cultivars during fruit growth and maturation (2005) Food Chemistry, 93, pp. 599-605Tan, C.P., Man, Y.B.C., Differential scanning calorimetric analysis of edible oils: Comparison of thermal properties and chemical composition (2000) Journal of the American Oil Chemist's Society, 77, pp. 143-155Tappin, M.R.R., Nakamura, M.J., Siani, A.C., Lucchetti, L., Development of an HPLC method for the determination of tetranortriterpenoids in Carapa guianensis seed oil by experimental design (2008) Journal of Pharmaceutical and Biomedical Analysis, 48, pp. 1090-1095Tian, Q., Schwartz, S.J., Mass spectrometry and tandem mass spectrometry of citrus limonoids (2003) Analytical Chemistry, 75, pp. 5451-5460Willerding, A.L., Carvalho-Neto, F.G.M.R., da Gama, A.M., Carioca, C.R.F., de Oliveira, L.A., Hydrolytic activity of bacterial lipases in Amazonian vegetable oils (2012) Quimica Nova, 35, pp. 1782-1785Yamamoto, T., Ogura, M., Amano, A., Adachi, K., Hagiwara, T., Kanisawa, T., Synthesis and odor of optically active 2-n-hexyl- and 2-n-heptylcyclopentanone and the corresponding δ-lactones (2002) Tetrahedron Letters, 43, pp. 9081-9084Zhao, C.X., Liang, Y.Z., Fang, H.Z., Li, X.N., Temperature-programmed retention indices for gas chromatography-mass spectroscopy analysis of plant essential oils (2006) Journal of Chromatography A, 1096, pp. 76-8

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL.

NOTCH1 is a well-established lineage specifier for T cells and among the most frequently mutated genes throughout all subclasses of T cell acute lymphoblastic leukemia (T-ALL). How oncogenic NOTCH1 signaling launches a leukemia-prone chromatin landscape during T-ALL initiation is unknown. Here we demonstrate an essential role for the high-mobility-group transcription factor Tcf1 in orchestrating chromatin accessibility and topology, allowing aberrant Notch1 signaling to convey its oncogenic function. Although essential, Tcf1 is not sufficient to initiate leukemia. The formation of a leukemia-prone epigenetic landscape at the distal Notch1-regulated Myc enhancer, which is fundamental to this disease, is Tcf1-dependent and occurs within the earliest progenitor stage even before cells adopt a T lymphocyte or leukemic fate. Moreover, we discovered a unique evolutionarily conserved Tcf1-regulated enhancer element in the distal Myc-enhancer, which is important for the transition of preleukemic cells to full-blown disease

The extrapituitary prolactin promoter polymorphism is associated with rheumatoid arthritis and anti-CCP antibodies in Mexican population

Background and objective: Women with multiple sclerosis (MS) who intend to get pregnant are often advised to discontinue disease modifying therapy (DMT) prior to conception. This recommendation is not based on medical evidence and may interfere with disease control by immunomodulatory drugs. The present study was designed to help discuss the effect of DMT for MS on pregnancy and on disease course. Patients and methods: Retrospective data from 152 pregnancies of 132 women with MS were collected by the physician in charge of the case. All data were entered into a specific file for qualitative and quantitative statistical analysis. Results: From the total group of patients, 89 pregnancies occurred without any exposure to MS drugs, while 61 pregnancies occurred with at least eight weeks of exposure to MS immunomodulatory drugs. The rate of obstetric and neonatal complications was similar in both groups, except for the newborn weight and height which was smaller for mothers receiving medications. Mothers' post-delivery relapse rate and EDSS scores in the follow-up period were significantly higher in the absence of treatment. Conclusion: It is possible that, with further such supportive data, international guidelines on MS treatment in young women who intend to get pregnant may need to be revised. " 2012 Elsevier B.V.",,,,,,"10.1016/j.clineuro.2012.04.024",,,"http://hdl.handle.net/20.500.12104/45105","http://www.scopus.com/inward/record.url?eid=2-s2.0-84872295057&partnerID=40&md5=c20df0b7feedea45f4a1222a90afb6b2",,,,,,"2",,"Clinical Neurology and Neurosurgery",,"15

The effects of long-term exposure to disease-modifying drugs during pregnancy in multiple sclerosis

Background and objective: Women with multiple sclerosis (MS) who intend to get pregnant are often advised to discontinue disease modifying therapy (DMT) prior to conception. This recommendation is not based on medical evidence and may interfere with disease control by immunomodulatory drugs. The present study was designed to help discuss the effect of DMT for MS on pregnancy and on disease course. Patients and methods: Retrospective data from 152 pregnancies of 132 women with MS were collected by the physician in charge of the case. All data were entered into a specific file for qualitative and quantitative statistical analysis. Results: From the total group of patients, 89 pregnancies occurred without any exposure to MS drugs, while 61 pregnancies occurred with at least eight weeks of exposure to MS immunomodulatory drugs. The rate of obstetric and neonatal complications was similar in both groups, except for the newborn weight and height which was smaller for mothers receiving medications. Mothers' post-delivery relapse rate and EDSS scores in the follow-up period were significantly higher in the absence of treatment. Conclusion: It is possible that, with further such supportive data, international guidelines on MS treatment in young women who intend to get pregnant may need to be revised. © 2012 Elsevier B.V

Multiple Sclerosis In South America: Month Of Birth In Different Latitudes Does Not Seem To Interfere With The Prevalence Or Progression Of The Disease [esclerose Múltipla Na América Do Sul: Mês De Nascimento Em Diferentes Latitudes Não Parece Interferir Com A Prevalência Ou Progressão Da Doença]

Objective: To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life. Methods: Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression. Results: Analysis of data from 1207 MS patients and 1207 control subjects did not show any significant variation in the month of birth regarding the prevalence of MS in four latitude bands (0-10; 11-20; 21-30; and 31-40 degrees). There was no relationship between the month of birth and the severity of disease in each latitude band. Conclusion: The results from this study show that MS patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes.719:00 AM573579Templer, D.I., Trent, N.H., Spencer, D.A., Season of birth in multiple sclerosis (1992) Acta Neurol Scand, 85, pp. 107-109Bharanidharan, P., Monthly distribution of multiple sclerosis patients' births (1997) Int J Biometeorol, 40, pp. 117-118Salemi, G., Ragonese, P., Aridon, P., Is season of birth associated with multiple sclerosis? (2000) Acta Neurol Scand, 101, pp. 381-383Salzer, J., Svenningsson, A., Sundström, P., Season of birth and multiple sclerosis in Sweden (2010) Acta Neurol Scand, 122, pp. 70-73Bayes, H.K., Weir, C.J., O'Leary, C., Timing of birth and risk of multiple sclerosis in the Scottish population (2010) Eur Neur, 63, pp. 36-40Saastamoinen, K.P., Auvinen, M.K., Tienari, P.J., Month of birth is associated with multiple sclerosis but not with HLA-DR15 in Finland (2012) Mult Scler, 18, pp. 563-568Fernandes de Abreu, D.A., Babron, M.C., Rebeix, I., Season of birth and not vitamin D receptor promoter polymorphisms is a risk factor for multiple sclerosis (2009) Mult Scler, 15, pp. 1146-1152Willer, C.J., Dyment, D.A., Sadovnick, A.D., Timing of birth and risk of multiple sclerosis: Population based study (2005) BMJ, 330, p. 120. , Canadian Collaborative Study GroupDeussing, E.C., Jankosky, C.J., Clark, L.L., Estimated incidence of multiple sclerosis among United States Armed Forces personnel using the Defense Medical Surveillance System (2012) Mil Med, 177, pp. 594-600Staples, J., Ponsonby, A.L., Lim, L., Low maternal exposure to ultraviolet radiation in pregnancy, month of birth, and risk of multiple sclerosis in offspring: Longitudinal analysis (2010) BMJ, 340, p. 1640Givon, U., Zeilig, G., Dolev, M., The month of birth and the incidence of multiple sclerosis in the Israeli population (2012) Neuroepidemiology, 38, pp. 64-68Fragoso, Y.D., Shearer, K.D., Adoni, T., Month of birth does not seem to interfere with the development of multiple sclerosis later in life in Brazilian patients (2012) Neuroepidemiology, 39, pp. 70-71Koch, M., de Keyser, J., Tremlett, H., Timing of birth and disease progression in multiple sclerosis (2008) Mult Scler, 14, pp. 793-798Tremlett, H.L., Devonshire, V.A., Does the season or month of birth influence disease progression in multiple sclerosis? (2006) Neuroepidemiology, 26, pp. 195-198Poser, C.M., Paty, D.W., Scheinberg, L., New diagnostic criteria for multiple sclerosis: Guidelines for research protocols (1983) Ann Neurol, 13, pp. 227-231McDonald, W.I., Compston, A., Edan, G., Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis (2001) Ann Neurol, 50, pp. 121-127Polman, C.H., Reingold, S.C., Edan, G., Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria" (2005) Ann Neurol, 58, pp. 840-846Kurtzke, J.F., Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS) (1983) Neurology (Cleveland), 33, pp. 1444-1452Damasceno, A., von Glehn, F., de Deus-Silva, L., Monthly variation of multiple sclerosis activity in the Southern hemisphere: Analysis from 996 relapses in Brazil (2012) Eur J Neurol, 19, pp. 660-662Altmann, D.M., Review series on helminths, immune modulation and the hygiene hypothesis: Nematode coevolution with adaptive immunity, regulatory networks and the growth of inflammatory diseases (2009) Immunology, 126, pp. 1-2Correale, J., Farez, M.F., The impact of environmental infections (parasites) on MS activity (2011) Mult Scler, 17, pp. 1162-1169Watson, P.E., McDonald, B.W., Seasonal variation of nutrient intake in pregnancy: Effects on infant measures and possible influence on diseases related to season of birth (2007) Eur J Clin Nutr, 61, pp. 1271-1280Melcon, M., Melcon, C., Bartoloni, L., Towards establishing MS prevalence in Latin America and the Caribbean (2013) Mult Scler, 19, pp. 145-152. , The "Grupo Colaborativo Multicéntrico para el Estudio de la Esclerosis Multiple en America Latina y el Caribe" (GEEMAL)Taylor, B.V., Pearson, J.F., Clarke, G., MS prevalence in New Zealand, an ethnically and latitudinally diverse country (2010) Mult Scler, 16, pp. 1422-1431Dobson, R., Giovannoni, G., Ramagopalan, S., The month of birth effect in multiple sclerosis: Systematic review, meta-analysis and effect of latitude (2013) J Neurol Neurosurg Psychiatry, 84, pp. 427-43

Measurement of D0D^0, D+D^+, Ds+D_s^+ and D∗+D^{*+} Production in Fixed Target 920-GeV Proton-Nucleus Collisions.

The inclusive production cross sections of the charmed mesons D^0, D^+, D_s^+ and D^{*+} have been measured in interactions of 920 GeV protons on C, Ti, and W targets with the HERA-B detector at the HERA storage ring. Differential cross sections as a function of transverse momentum and Feynman's x variable are given for the central rapidity region and for transverse momenta up to \pT=3.5 GeV/$c$. The atomic mass number dependence and the leading to non-leading particle production asymmetries are presented as well.Comment: Submitted to EPJ