21 research outputs found

    Il professionista riflessivo: apprendere dalla pratica professionale

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    Il professionista pu\uf2 arrivare a comprendere che la realizzazione di s\ue9 passa attraverso l\u2019esercizio e l\u2019interpretazione della propria professione. Il riconoscimento del legame tra lavoro e vita reale pu\uf2 spiegare da dove pu\uf2 scaturire la forza per dare una motivazione di senso a favore di ci\uf2 che fa, delle persone per cui lavora e dell\u2019ambiente che vuole contribuire a trasformare

    Long-Lasting Efficacy of Radio Electric Asymmetric Conveyer Neuromodulation Treatment on Functional Dysmetria, an Adaptive Motor Behavior

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    BackgroundFluctuating asymmetry (FA) is widely defined as the deviation from perfect bilateral symmetry and is considered an epigenetic measure of environmental stress. Rinaldi and Fontani hypothesized that the FA morpho-functional changes originate from an adaptive motor behavior determined by functional alterations in the cerebellum and neural circuits, not caused by a lesion, but induced by environmental stress. They called this phenomenon functional dysmetria (FD). On this premise, they developed the radio electric asymmetric conveyer (REAC) technology, a neuromodulation technology aimed at optimizing the best neuro-psycho-motor strategies in relation to environmental interaction.AimsPrevious studies showed that specific REAC neuro postural optimization (NPO) treatment can induce stable FD recovery. This study aimed to verify the duration of the NPO effect in inducing the stable FD recovery over timeMaterials and methodsData were retrospectively collected from a population of 29,794 subjects who underwent a specific semiological FD assessment and received the NPO treatment, regardless of the pathology referred.ResultsThe analysis of the data collected by the various participants in the study led us to ascertain the disappearance of FD in 100% of the cases treated, with a stability of the result detected up to 18 years after the single administration of the REAC NPO treatment.ConclusionsThe REAC NPO neurobiological modulation treatment consisting of a single administration surprisingly maintains a very long efficacy in the correction of FD. This effect can be explained as the long-lasting capacity of the NPO treatment to induce greater functional efficiency of the brain dynamics as proven in previous studies

    Drag in wet granular materials

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    We have studied experimentally the effect of the water content on the drag force applied by a wet granular system on a probe moving through it at constant velocity. Similar to what has been observed for dry granular systems, the drag force is found to be independent of the velocity of the probe. By comparing our result with the dry case, we have shown that three main physical mechanisms occur: cohesion (consequence of capillary forces), contact lubrication and dilatancy induced by cohesion. The influence of the latter mechanism prevails in our system and the relative influence of the two former ones is found to depend on grains' characteristics. At important water contents, the granular system may become heterogeneous and its structure is modified by the motion of the probe. Our analysis is strengthened by shear cell experiments which also point out the importance of the geometry of the system on the effect of the water content

    Facilitating the Use of the Theory of Representative Sampling for Granular Waste: Number of Particles, Sample Size and Uncertainty Arising From Sampling

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    International audienceEnvironmental forensics assessments are often based on few analytical measurements. Biased data can, therefore, led the involved actors to be improperly charged or acquitted. Data reliability, considered in terms of uncertainty and variability, is determined by the analytical methods and the performed sampling procedures. The influence of this latter increases with highly heterogeneous materials characterized by the presence of trace, “rare” elements (both considered resources or contaminants), as occurring in the field of waste management. Nevertheless, the theoretical principles behind representative sampling are still not well understood in the waste community, which often underestimates its influence on the reliability of the resulting data and consequent decisions. Applying the binomial probability distribution, the theory of representative sampling is reviewed to facilitate its use for granular solid wastes. The concept of the number of particles n that shall compose a representative sample is introduced. Within n, the same fraction p shall be included of “rare” particles present in the lot to be characterized. Also, n depends on the minimum achievable variability of test results, i.e., coefficient of variation CV computable on a set of equivalent samples. Data are presented quantifying occurring intra and inter-laboratory variability of the most used chemical-physical and ecotoxicological analyses of homogeneous material. Accordingly, a specific formula to calculate n is proposed. Three requirements are then laid down to transform n into mass of sample. Representative samples must include a fraction p of particles considered “rare” in terms of i) presence/concentration of substances and ii) particles size distribution, since large waste particles are seldom characterized by the same composition of fine particles. Further, iii) the size of the sampling equipment shall prevent segregation of larger particles. The mass of a representative sample is calculated by reconciling these three conditions. According to the dedicated technical standards, the layout of a replication experiment is developed to measure the uncertainty arising from a sampling plan designed for waste classified with European Waste Code 191212 “other wastes including mixtures of materials from mechanical treatment of wastes”.Practical and design challenges that can affect the correct performance of the related experimental activities and the reliability of the outcomes are discussed

    Intramolecular Aminoazidation of Unactivated Terminal Alkenes by Palladium-Catalyzed Reactions with Hydrogen Peroxide as the Oxidant

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    The palladium-catalyzed aminoazidation of aminoalkenes yielding azidomethyl-substituted nitrogen-containing heterocycles was developed. The procedure requires oxidative conditions and occurs at room temperature in the presence of hydrogen peroxide and NaN3 as the azide source. These conditions provide selective exo-cyclization/azidation of the carbon-carbon double bond, furnishing a versatile approach toward five-, six-, and seven-membered heterocyclic rings

    In vitro development of engineered muscle using a scaffold based on the pressure-activated-microsyringe (PAM) technique

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    The development of new human skeletal muscle tissue is an alternative approach to the replacement of tissue after severe damage, for example in the case of traumatic injury, where surgical reconstruction is often needed following major loss of natural tissue. Treatment to date has involved the transfer of muscle tissue from other sites, resulting in a functional loss and volume deficiency of donor sites. Approaches that seek to eliminate these problems include the relatively new solution of skeletal muscle engineering. Here there are two main components to consider: (a) the cells with their regenerative potential; and (b) the polymeric structure onto which cells are seeded and where they must perform their activities. In this paper we describe well-defined two- and three-dimensional polymeric structures able to drive the myoblast process of adhesion, proliferation and differentiation. We examine a series of polymers and protein adhesions with which to functionalize the structures, and cell-seeding methods, with a view to defining the optimal protocol for engineering skeletal muscle tissue. All polymer samples were tested for their mechanical and biological properties, to support the validity of our results in the real context of muscle tissue engineering

    Site location and crystal field of Nd3+ ions in congruent strontium barium niobate

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    The site location of Nd3+ ions in congruent strontium barium niobate (Sr0.6Ba0.4Nb2O6) has been systematically investigated by means of low-temperature optical and electron paramagnetic resonance spectroscopies. The experimental results obtained by these complementary techniques clearly indicate that Nd3+ ions are mainly located in only one of the four available cationic sites, the A2 sites, and preserving the C-s local symmetry of these host cation sites. The energy levels and g-factor value experimentally obtained by both techniques have been used to calculate the crystal field parameters for the Nd3+ ions in this A2 cationic site
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