Seguimento de 5 anos de acuidade visual de pacientes com degeneração macular relacionada à idade exudativa (ÚMIDA) tratada com radioterapia e medicamentos antiangiogênicos / 5 years follow-up of visual acuity from patients with exudative (WET) age-related macular degeneration, treated with radiotherapy and antiangiogenic drugs

Objetivo: a degeneração macular relacionada à idade (DMRI) é atualmente uma das principais causas de deficiência visual grave em pacientes com mais de 55 anos. Existem aproximadamente 170 milhões de pessoas com alguma forma da doença em todo o mundo. Os tratamentos atuais da forma exsudativa ainda apresentam limitações, principalmente relacionadas à necessidade de inúmeras injeções intravítreas de antiangiogênicos ao longo do seguimento. O objetivo deste estudo é avaliar a acuidade visual e estabilidade de pacientes tratados com radioterapia intraocular com estrôncio 90 e duas injeções intravítreas de bevacizumabe nos 16 pacientes do grupo I, e uma aplicação de radioterapia intraocular com estrôncio 90 e duas injeções intravítreas de ranibizumabe em 13 pacientes no grupo II durante um acompanhamento de 5 anos.Métodos: Todos os 29 pacientes apresentaram neovascularização de coróide secundária à DMRI e foram acompanhados com exame oftalmológico completo, angiografia de fluorescência e tomografia de coerência óptica.Resultados: 87,5% dos pacientes do grupo I e 53,84% do grupo II mantiveram boa acuidade visual ao final dos 60 meses de seguimento. A média da melhor acuidade visual corrigida apresentou ganho de + 10,4 letras e + 5,23 letras, respectivamente, em tabela específica. O grupo bevacizumabe manteve-se estável ao longo do acompanhamento, além de um maior número de pacientes que alcançou acuidade visual ? 20/40.Conclusão: A radioterapia intraocular combinada com antiangiogênicos se enquadra no arsenal terapêutico disponível para DMRI neovascular como uma opção segura, especialmente nos casos que ocorrem com injeções intravítreas repetidas.

Diagnósticos de enfermagem relacionados ao politraumatismo em atendimento pré-hospitalar móvel

The aim was to identify the most frequent nursing diagnoses in occurrences of multiple trauma, since this activity, exclusive to nurses, is recognized for its work of excellence in pre-hospital care. The results help nurses to act in the context of trauma emergencies and highlight the potential of nursing diagnoses in prioritizing care for patients who are victims of multiple traumas. It was evidenced that the Acute Pain diagnosis was more prevalent, even though pain is subjective and the target of lived experiences in relation to sensory perception. Then, the diagnosis of Impaired Physical Mobility, which involves the ability to move and the immobilizations performed during care, and then the diagnoses related to oxygenation and breathing, such as Ineffective Breathing Pattern and Impaired Gas Exchange. Specific nursing interventions for the diagnoses found were presented.Objetivou-se identificar os diagnósticos de enfermagem mais frequentes em ocorrências de politraumatismo, uma vez que essa atividade, privativa do enfermeiro, é reconhecida pelo seu trabalho de excelência no atendimento pré-hospitalar. Os resultados auxiliam na atuação do enfermeiro no cenário das emergências em trauma e salientam o potencial dos diagnósticos de enfermagem na priorização da assistência às pacientes vítimas de múltiplos traumas. Evidenciou-se que o diagnóstico Dor Aguda teve mais prevalência, mesmo a dor sendo subjetiva e alvo de experiências vividas em relação a percepção sensorial. Em seguida, o diagnóstico de Mobilidade Física Prejudicada, que envolve a capacidade de mover-se e as imobilizações feitas no atendimento, e então os diagnósticos relacionados à oxigenação e respiração, como Padrão Respiratório Ineficaz e Troca de Gases Prejudicada. Intervenções de enfermagem específicas para os diagnósticos encontrados foram apresentadas

Diagnósticos de enfermagem relacionados ao politraumatismo em atendimento pré-hospitalar móvel

The aim was to identify the most frequent nursing diagnoses in occurrences of multiple trauma, since this activity, exclusive to nurses, is recognized for its work of excellence in pre-hospital care. The results help nurses to act in the context of trauma emergencies and highlight the potential of nursing diagnoses in prioritizing care for patients who are victims of multiple traumas. It was evidenced that the Acute Pain diagnosis was more prevalent, even though pain is subjective and the target of lived experiences in relation to sensory perception. Then, the diagnosis of Impaired Physical Mobility, which involves the ability to move and the immobilizations performed during care, and then the diagnoses related to oxygenation and breathing, such as Ineffective Breathing Pattern and Impaired Gas Exchange. Specific nursing interventions for the diagnoses found were presented.Objetivou-se identificar os diagnósticos de enfermagem mais frequentes em ocorrências de politraumatismo, uma vez que essa atividade, privativa do enfermeiro, é reconhecida pelo seu trabalho de excelência no atendimento pré-hospitalar. Os resultados auxiliam na atuação do enfermeiro no cenário das emergências em trauma e salientam o potencial dos diagnósticos de enfermagem na priorização da assistência às pacientes vítimas de múltiplos traumas. Evidenciou-se que o diagnóstico Dor Aguda teve mais prevalência, mesmo a dor sendo subjetiva e alvo de experiências vividas em relação a percepção sensorial. Em seguida, o diagnóstico de Mobilidade Física Prejudicada, que envolve a capacidade de mover-se e as imobilizações feitas no atendimento, e então os diagnósticos relacionados à oxigenação e respiração, como Padrão Respiratório Ineficaz e Troca de Gases Prejudicada. Intervenções de enfermagem específicas para os diagnósticos encontrados foram apresentadas

Factors associated with grazing behavior in candidates for bariatric surgery at a hospital in the Amazon

BlackgroundTo assess grazing behavior and associated factors in candidates for bariatric surgery monitored at a public hospital that is a reference in the care of people with severe obesity.MethodsCross-sectional analytical study, with candidates for bariatric surgery of both genders, treated in a public hospital in the Amazon. To assess grazing behavior, the Repetitive Eating Questionnaire was used, and to investigate patterns of eating behavior, the Three Factor Eating Questionnaire was used, which assesses: Emotional Eating, Cognitive Restriction and Uncontrolled Eating. Sociodemographic information was obtained through self-report and the description of medication use through the medical record. Body mass index (BMI) was also calculated by measuring weight and height. The SPSS program, v. 21.0 was used. The study was approved by the Research Ethics Committee.ResultsA total of 205 participants were evaluated, with a mean age of 37.5 ± 8.6 years, the majority (93.7%) being women and the majority (59.5%) was not also using medication to lose weight. About 66.3% of the participants had compulsive grazing. The factor with the highest score was cognitive restriction (p < 0.001). Individuals who used weight loss drugs had higher scores in the cognitive restriction factor (p = 0.015) and lower scores for uncontrolled eating (p = 0.008), compulsive grazing (p = 0.021) and non-compulsive grazing (p = 0.034).ConclusionLinear regression showed that emotional eating and uncontrolled eating were predictors of both compulsive grazing and non-compulsive grazing behavior. It was observed that grazing behavior, cognitive restriction, emotional eating and uncontrolled eating are present and correlated in the studied patients. In addition, the use of weight loss drugs seems to help reduce dysfunctional eating behaviors in patients with severe obesity

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

The decay $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ is studied in proton-proton collisions at a center-of-mass energy of $\sqrt{s}=13$ TeV using data corresponding to an integrated luminosity of 5 $\mathrm{fb}^{-1}$ collected by the LHCb experiment. In the $\Lambda_{c}^+ K^{-}$ system, the $\Xi_{c}(2930)^{0}$ state observed at the BaBar and Belle experiments is resolved into two narrower states, $\Xi_{c}(2923)^{0}$ and $\Xi_{c}(2939)^{0}$, whose masses and widths are measured to be $$m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV},$$ where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt $\Lambda_{c}^{+} K^{-}$ sample. Evidence of a new $\Xi_{c}(2880)^{0}$ state is found with a local significance of $3.8\,\sigma$, whose mass and width are measured to be $2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV}$ and $12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}$, respectively. In addition, evidence of a new decay mode $\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-}$ is found with a significance of $3.7\,\sigma$. The relative branching fraction of $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ with respect to the $B^{-} \to D^{+} D^{-} K^{-}$ decay is measured to be $2.36 \pm 0.11 \pm 0.22 \pm 0.25$, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

Measurement of the ratios of branching fractions R(D∗)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

The ratios of branching fractions $\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu})$ and $\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu})$ are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb${ }^{-1}$ of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode $\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}$. The measured values are $\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024$ and $\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066$, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is $\rho=-0.43$. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Educomunicação, Transformação Social e Desenvolvimento Sustentável

Esta publicação apresenta os principais trabalhos dos GTs do II Congresso Internacional de Comunicação e Educação nos temas&nbsp;Transformação social, com os artigos que abordam principalmente Educomunicação e/ou Mídia-Educação, no contexto de políticas de diversidade, inclusão e equidade; e, em Desenvolvimento Sustentável&nbsp;os artigos que abordam os avanços da relação comunicação/educação no contexto da educação ambiental e desenvolvimento sustentável