434 research outputs found
Comprehensive Characterization of Raw Simvastatin and Fasudil as Therapeutics in Targeted Pulmonary Drug Delivery for Pulmonary Hypertension
Beta-diversity of Central European forests decreases along an elevational gradient due to the variation in local community assembly processes
Beta-diversity has been repeatedly shown to decline with increasing
elevation, but the causes of this pattern remain unclear, partly because they
are confounded by coincident variation in alpha- and gamma-diversity. We used
8,795 forest vegetation-plot records from the Czech National Phytosociological
Database to compare the observed patterns of beta diversity to null-model
expectations (beta-deviation) controlling for the effects of alpha- and
gamma-diversity. We tested whether \b{eta}-diversity patterns along a 1,200 m
elevation gradient exclusively depend on the effect of varying species pool
size, or also on the variation of the magnitude of community assembly
mechanisms determining the distribution of species across communities (e.g.,
environmental filtering, dispersal limitation). The null model we used is a
novel extension of an existing null-model designed for presence/absence data
and was specifically designed to disrupt the effect of community assembly
mechanisms, while retaining some key features of observed communities such as
average species richness and species abundance distribution. Analyses were
replicated in ten subregions with comparable elevation ranges. Beta-diversity
declined along the elevation gradient due to a decrease in gamma-diversity,
which was steeper than the decrease in alpha-diversity. This pattern persisted
after controlling for alpha- and gamma-diversity variation, and the results
were robust when different resampling schemes and diversity metrics were used.
We conclude that in temperate forests the pattern of decreasing beta-diversity
with elevation does not exclusively depend on variation in species pool size,
as has been hypothesized, but also on variation in community assembly
mechanisms. The results were consistent across resampling schemes and diversity
measures, thus supporting the use of vegetation plot databases for
understanding...Comment: Accepted version 25 pages, 5 figures, 1 tabl
Evolución de las garantías de derechos laborales de las trabajadoras domésticas en Colombia a partir del año 2014 en el marco de la transnacionalización del campo jurídico
Las trabajadoras domésticas en Colombia han sido víctimas de violaciones de derechos laborales por parte del Estado. Ante esto, se han fortalecido y organizado en distintas asociaciones y sindicatos. Adicionalmente, han establecido redes de cooperación con distintos actores a nivel transnacional, lo cual ha conllevado a la transnacionalización del campo jurídico; y a alcanzar logros importantes que pueden evidenciarse en la evolución de la jurisprudencia colombiana. Un ejemplo de ello, es la ratificación del "Convenio Nº189 sobre los Trabajadores y Trabajadoras Domésticas del año 2011", de la Organización Internacional del Trabajo (OIT) por parte del Estado Colombiano.Female domestic workers in Colombia, have been victims of labor rights violations by the Colombian State. Given this situation, domestic workers have strengthened themselves, and organized in several associations and trade unions. In addition, they have established cooperative networks with many transnational actors, which has led to the legal area transnationalization and has made it possible to accomplish some important achievements that can be seen in the evolution of the Colombian jurisprudence. To set an example of it, there is the ratification of International Labour Organization "Domestic Workers Convention Nº189, 2011" by the Colombian State.InternacionalistaPregrad
Estudio e implementación de un controlador para un robot tipo Segway y de los algoritmos que lo capacitan para el seguimiento de trayectorias desconocidas
Proyecto de Planificación Recursos Empresariales Módulo de presupuesto UTN. Aplicativo: Sistema de Gestión del proceso de ejecución, seguimiento y liquidación del presupuesto UTN.
Las personas y las organizaciones se desenvuelven en varios ámbitos, uno de ellos es el económico, lamentablemente esta área es inestable, predomina la incertidumbre. Por esto, es importante que se planeen las actividades a través de un presupuesto, dado que cuanto menor sea el riesgo menor será la incertidumbre[1].
El Presupuesto es uno de los ejes fundamentales de la gestión financiera dentro de una organización permitiendo planear los recursos (ingresos) con los que se cuenta, para dar cumplimiento a los planes operativos desarrollados (gastos) y cuyo grado de medición se lo realiza en su ejecución; y es ahí donde el presupuesto logra su propósito midiendo lo real con lo planificado y la gestión administrativa; además el presupuesto es susceptible a cambios ya que las finanzas son inestables por diferentes factores: mala planificación, imprevistos no contemplados, necesidades adicionales etc., por lo que se debe contar con estrategias que permitan modificar la presupuestación, a fin de que la gestión organizacional pueda quedar encuadrada entre el Presupuesto, la Decisión y el Control, ya que la aceptación de las pautas de conductas previamente establecidas constituye la única norma para evaluar, premiar o rectificar la ejecución realizada.Proyecto de Planificación Recursos Empresariales Módulo de presupuesto UTN. Aplicativo: Sistema de Gestión del proceso de ejecución, seguimiento y liquidación del presupuesto UTN
Esperanza en Pacientes Oncológicos Paliativos hacia una revisión sistemática
Objetivo. Revisión sobre el término esperanza. Método. Estudio sistemático, en el que se han seleccionado 31 artículos con población oncológica adulta, en estadio terminal, de edades entre 20 a 88 años, de ambos géneros. Resultado. La esperanza, es inherente para la vida del ser humano, es una expectativa del futuro, dinámica, cambiante, fluctuante, medible y multifacética; presenta dos connotaciones como verbo y como sustantivo. La esperanza se puede mantener y fomentar mediante estrategias personales del paciente, del entorno social y de los profesionales de la salud; además, existen herramientas, técnicas, programas y psicoterapias que facilitan dichos resultados. Conclusión. La esperanza se puede fomentar, mantener y fortalecer y es fundamental para esta etapa de enfermedad. No existe un protocolo de intervención específico, lo principal es escuchar al paciente
Relación entre inteligencia emocional y suicidio: una revisión sistemática
En Colombia actualmente existen numerosas problemáticas de salud pública, sin embargo, el suicidio es uno de los más prevalentes. Este problema es precedido por un conjunto de eventos que buscan de forma intencional acabar con la vida, y esto se conoce como comportamiento o conducta suicida, el cual es consecuencia de reacciones emocionales mal gestionadas que entrañan un déficit en la inteligencia emocional de un individuo; es por eso que esta es de vital importancia, ya que permite que un sujeto conozca, comprenda y gestione de manera asertiva las diferentes emociones que experimenta a lo largo de su existencia. Objetivo: Conocer/identificar la relación que existe entre el suicidio y la inteligencia emocional.In Colombia there are currently numerous public health problems, however, suicide is one of the most prevalent. This problem is preceded by a set of events that intentionally seek to end life, and this is known as suicidal behavior or behavior, which is a consequence of poorly managed emotional reactions that entail a deficit in the emotional intelligence of an individual; that is why this is of vital importance, since it allows a subject to know, understand and assertively manage the different emotions that he experiences throughout his existence. Objective: To know/identify the relationship between suicide and emotional intelligence
Haemolysis and lipemia interfere with resistin and myeloperoxidase BioVendor ELISA assays
Introduction: The aim of our study was to investigate the influence of haemolysis and lipemia on resistin (RES) and myeloperoxidase (MPO) measurement by BioVendor enzyme-linked immunosorbent assays (ELISA).
Materials and methods: Blood was taken from healthy volunteers into lithium heparin tubes. Plasma samples were spiked with Lipofundin®
emulsion (B. Braun Melsungen AG, Germany) for lipemia interference testing. Haemolysed samples were obtained by drawing aliquots of heparinized blood through a 26 gauge needle. Index of haemolysis (H), lipemia (L) and triglyceride concentration were measured on Abbott Architect c8000. Haemoglobin concentration was measured on Sysmex XN-1000. Concentrations of RES and MPO in all samples were determined with RES and MPO ELISA kits (BioVendor, Czech Republic). All measurements were performed in triplicate. Biases from the native samples were calculated for both analytes and compared with an arbitrary value (e.g. ± 10%).
Results: Triglyceride concentration in the investigated samples ranged from 0.57 to 38.23 mmol/L, which corresponds to L index from - 0.01 to
13.77. Haemoglobin concentration in all samples ranged from 0 to 8 g/L which correspond to H index from 0.05 to 8.77. Both MPO and RES showed significant biases at 1 g/L haemoglobin (58.7% and 66.7%, respectively). Also, both MPO and RES showed significant biases at 4.66 mmol/L triglycerides (33.8% and - 12.2%, respectively).
Conclusions: Resistin BioVendor assays are affected by haemolysis and lipemia already at low degree of interferent. Haemolysis was found to interfere at 1 g/L haemoglobin for both assays, while lipemia interferes at 4.66 mmol/L of triglycerides
Delivering an In-Home Exercise Program via Telerehabilitation: A Pilot Study of Lung Transplant Go (LTGO)
We evaluated the feasibility, safety, system usability, and intervention acceptability of Lung Transplant Go (LTGO), an 8-week in-home exercise intervention for lung transplant recipients using a telerehabilitation platform, and described changes in physical function and physical activity from baseline to post-intervention. The intervention was delivered to lung transplant recipients in their home via the Versatile and Integrated System for TeleRehabilitation (VISYTER). The intervention focused on aerobic and strengthening exercises tailored to baseline physical function. Participants improved walk distance (6-minute walk distance), balance (Berg Balance Scale), lower body strength (30-second chair stand test) and steps walked (SenseWear Armband®). No adverse events were reported. Participants rated the program highly positively in regard to the technology and intervention. The telerehabilitation exercise program was feasible, safe, and acceptable. Our findings provide preliminary support for the LTGO intervention to improve physical function and promote physical activity in lung transplant recipients.
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