130 research outputs found

    Current state and future of pediatric allergology in Europe: A road map

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    The history of pediatric allergology (PA) in Europe is relatively youthful, dating back to 1984, when a small group of pediatricians founded the European Working Group on Pediatric Allergy and Immunology—later giving rise to ESPACI (European Society on Pediatric Allergology and Clinical Immunology). In 1990, the first dedicated journal, Pediatric Allergy and Immunology (PAI), was founded. There are striking differences across Europe, and even within European countries, in relation to the training pathways for doctors seeing children with allergic disease(s). In 2016, the EAACIClemens von Pirquet Foundation (CvP) organized and sponsored a workshop with the European Academy of Allergy and Clinical Immunology (EAACI) Pediatric Section. This collaboration focussed on the future of PA and specifically on education, research, and networking/ advocacy. The delegates representing many countries across Europe have endorsed the concept that optimal care of children with allergic diseases is delivered by pediatricians who have received dedicated training in allergy, or allergists who have received dedicated training in pediatrics. In order to meet the needs of children and families with allergic disease(s), the pediatric allergist is highly encouraged to develop several networks. Our challenge is to reinforce a clear strategic approach to scientific excellence to across our member base and to ensure and enhance the relevance of European pediatric research in allergy. With research opportunities in basic, translational, clinical, and epidemiologic trials, more trainees and trained specialists are needed and it is an exciting time to be a pediatric allergologist

    Measurement of the W boson mass

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    International audienceThe W boson mass is measured using proton-proton collision data at s \sqrt{s} = 13 TeV corresponding to an integrated luminosity of 1.7 fb1^{−1} recorded during 2016 by the LHCb experiment. With a simultaneous fit of the muon q/pT_{T} distribution of a sample of W → μν decays and the ϕ^{*} distribution of a sample of Z → μμ decays the W boson mass is determined to bemw=80354±23stat±10exp±17theory±9PDFMeV, {m}_w=80354\pm {23}_{\mathrm{stat}}\pm {10}_{\mathrm{exp}}\pm {17}_{\mathrm{theory}}\pm {9}_{\mathrm{PDF}}\mathrm{MeV}, where uncertainties correspond to contributions from statistical, experimental systematic, theoretical and parton distribution function sources. This is an average of results based on three recent global parton distribution function sets. The measurement agrees well with the prediction of the global electroweak fit and with previous measurements.[graphic not available: see fulltext

    Associated production of prompt J/ψJ/\psi and Υ\mathit{\Upsilon} mesons in pppp collisions at s=13TeV\sqrt{s}=13\,\mathrm{TeV}

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    International audienceThe associated production of prompt J/ψJ/\psi and Υ\mathit{\mathit{\Upsilon}} mesons in pppp collisions at a centre-of-mass energy of s=13TeV\sqrt{s}=13\,\mathrm{TeV} is studied using LHCb data, corresponding to an integrated luminosity of 4fb14\,\mathrm{fb}^{-1}. The measurement is performed for J/ψJ/\psi (Υ\mathit{\Upsilon}) mesons with a transverse momentum pT<10(30)GeV/cp_{\mathrm{T}}<10\,(30)\,\mathrm{GeV}/c in the rapidity range 2.0<y<4.52.0<y<4.5. In this kinematic range, the cross-section of the associated production of prompt J/ψJ/\psi and Υ(1S)\mathit{\Upsilon}(1S) mesons is measured to be 133±22±7±3pb133 \pm 22 \pm 7 \pm 3 \, \mathrm{pb}, with a significance of 7.9σ7.9\,\sigma, and that of prompt J/ψJ/\psi and Υ(2S)\mathit{\Upsilon}(2S) mesons to be 76±21±4±7pb76\pm 21 \pm 4 \pm 7 \, \mathrm{pb}, with a significance of 4.9σ4.9\,\sigma. The first uncertainty is statistical, the second systematic, and the third due to uncertainties on the used branching fractions. This is the first observation of the associated production of J/ψJ/\psi and Υ(1S)\mathit{\Upsilon}(1S) in proton-proton collisions. Differential cross-sections are measured as function of variables that are sensitive to kinematic correlations between the J/ψJ/\psi and Υ(1S)\mathit{\Upsilon}(1S) mesons. The effective cross-sections of the associated production of prompt J/ψJ/\psi and Υ\mathit{\Upsilon} mesons are obtained and found to be compatible with measurements using other particle productions

    Measurement of the double-differential inclusive jet cross section in proton-proton collisions at s\sqrt{s} = 5.02 TeV

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    International audienceThe inclusive jet cross section is measured as a function of jet transverse momentum pTp_\mathrm{T} and rapidity yy. The measurement is performed using proton-proton collision data at s\sqrt{s} = 5.02 TeV, recorded by the CMS experiment at the LHC, corresponding to an integrated luminosity of 27.4 pb1^{-1}. The jets are reconstructed with the anti-kTk_\mathrm{T} algorithm using a distance parameter of RR = 0.4, within the rapidity interval y\lvert y\rvert<\lt 2, and across the kinematic range 0.06 <\ltpTp_\mathrm{T}<\lt 1 TeV. The jet cross section is unfolded from detector to particle level using the determined jet response and resolution. The results are compared to predictions of perturbative quantum chromodynamics, calculated at both next-to-leading order and next-to-next-to-leading order. The predictions are corrected for nonperturbative effects, and presented for a variety of parton distribution functions and choices of the renormalization/factorization scales and the strong coupling αS\alpha_\mathrm{S}

    Measurement of the double-differential inclusive jet cross section in proton-proton collisions at s\sqrt{s} = 5.02 TeV

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    International audienceThe inclusive jet cross section is measured as a function of jet transverse momentum pTp_\mathrm{T} and rapidity yy. The measurement is performed using proton-proton collision data at s\sqrt{s} = 5.02 TeV, recorded by the CMS experiment at the LHC, corresponding to an integrated luminosity of 27.4 pb1^{-1}. The jets are reconstructed with the anti-kTk_\mathrm{T} algorithm using a distance parameter of RR = 0.4, within the rapidity interval y\lvert y\rvert<\lt 2, and across the kinematic range 0.06 <\ltpTp_\mathrm{T}<\lt 1 TeV. The jet cross section is unfolded from detector to particle level using the determined jet response and resolution. The results are compared to predictions of perturbative quantum chromodynamics, calculated at both next-to-leading order and next-to-next-to-leading order. The predictions are corrected for nonperturbative effects, and presented for a variety of parton distribution functions and choices of the renormalization/factorization scales and the strong coupling αS\alpha_\mathrm{S}

    Search for the lepton-flavour violating decays B0K0μ±eB^0 \to K^{*0} \mu^\pm e^\mp and Bs0ϕμ±eB_s^0 \to \phi \mu^\pm e^\mp

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    A search for the lepton-flavour violating decays B0K0μ±eB^0 \to K^{*0} \mu^\pm e^\mp and Bs0ϕμ±eB_s^0 \to \phi \mu^\pm e^\mp is presented, using proton-proton collision data collected by the LHCb detector at the LHC, corresponding to an integrated luminosity of 9fb19\,\text{fb}^{-1}. No significant signals are observed and upper limits of \begin{align} {\cal B}( B^0 \to K^{*0} \mu^+ e^- ) &< \phantom{1}5.7\times 10^{-9}~(6.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^- e^+ ) &< \phantom{1}6.8\times 10^{-9}~(7.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^\pm e^\mp ) &< 10.1\times 10^{-9}~(11.7\times 10^{-9}),\newline {\cal B}( B_s^0 \to \phi \mu^\pm e^\mp ) &< 16.0\times 10^{-9}~(19.8\times 10^{-9}) \end{align} are set at 90% (95%)90\%~(95\%) confidence level. These results constitute the world's most stringent limits to date, with the limit on the decay Bs0ϕμ±eB_s^0 \to \phi \mu^\pm e^\mp the first being set. In addition, limits are reported for scalar and left-handed lepton-flavour violating New Physics scenarios.A search for the lepton-flavour violating decays B0^{0} → K0^{*0}μ±^{±}e^{∓} and Bs0 {B}_s^0 → ϕμ±^{±}e^{∓} is presented, using proton-proton collision data collected by the LHCb detector at the LHC, corresponding to an integrated luminosity of 9 fb1^{−1}. No significant signals are observed and upper limits ofB(B0K0μ+e)<5.7×109(6.9×109),B(B0K0μe+)<6.8×109(7.9×109),B(B0K0μ±e)<10.1×109(11.7×109),B(Bs0ϕμ±e)<16.0×109(19.8×109) {\displaystyle \begin{array}{c}\mathcal{B}\left({B}^0\to {K}^{\ast 0}{\mu}^{+}{e}^{-}\right)<5.7\times {10}^{-9}\left(6.9\times {10}^{-9}\right),\\ {}\mathcal{B}\left({B}^0\to {K}^{\ast 0}{\mu}^{-}{e}^{+}\right)<6.8\times {10}^{-9}\left(7.9\times {10}^{-9}\right),\\ {}\mathcal{B}\left({B}^0\to {K}^{\ast 0}{\mu}^{\pm }{e}^{\mp}\right)<10.1\times {10}^{-9}\left(11.7\times {10}^{-9}\right),\\ {}\mathcal{B}\left({B}_s^0\to \phi {\mu}^{\pm }{e}^{\mp}\right)<16.0\times {10}^{-9}\left(19.8\times {10}^{-9}\right)\end{array}} are set at 90% (95%) confidence level. These results constitute the world’s most stringent limits to date, with the limit on the decay Bs0 {B}_s^0 → ϕμ±^{±}e^{∓} the first being set. In addition, limits are reported for scalar and left-handed lepton-flavour violating New Physics scenarios.[graphic not available: see fulltext]A search for the lepton-flavour violating decays B0K0μ±eB^0 \to K^{*0} \mu^\pm e^\mp and Bs0ϕμ±eB_s^0 \to \phi \mu^\pm e^\mp is presented, using proton-proton collision data collected by the LHCb detector at the LHC, corresponding to an integrated luminosity of 9fb19\,\text{fb}^{-1}. No significant signals are observed and upper limits of \begin{align} {\cal B}( B^0 \to K^{*0} \mu^+ e^- ) &< \phantom{1}5.7\times 10^{-9}~(6.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^- e^+ ) &< \phantom{1}6.8\times 10^{-9}~(7.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^\pm e^\mp ) &< 10.1\times 10^{-9}~(11.7\times 10^{-9}),\newline {\cal B}( B_s^0 \to \phi \mu^\pm e^\mp ) &< 16.0\times 10^{-9}~(19.8\times 10^{-9}) \end{align} are set at 90% (95%)90\%~(95\%) confidence level. These results constitute the world's most stringent limits to date, with the limit on the decay Bs0ϕμ±eB_s^0 \to \phi \mu^\pm e^\mp the first being set. In addition, limits are reported for scalar and left-handed lepton-flavour violating New Physics scenarios

    Multiplicity and transverse momentum dependence of charge-balance functions in pPb and PbPb collisions at LHC energies

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    International audienceMeasurements of the charge-dependent two-particle angular correlation function in proton-lead (pPb) collisions at a nucleon-nucleon center-of-mass energy of sNN\sqrt{s_\mathrm{NN}} = 8.16 TeV and lead-lead (PbPb) collisions atsNN\sqrt{s_\mathrm{NN}} = 5.02 TeV are reported. The pPb and PbPb datasets correspond to integrated luminosities of 186\nbinv and 0.607 nb1^{-1}, respectively, and were collected using the CMS detector at the CERN LHC. The charge-dependent correlations are characterized by balance functions of same- and opposite-sign particle pairs. The balance functions, which contain information about the creation time of charged particle pairs and the development of collectivity, are studied as functions of relative pseudorapidity (Δη\Delta \eta) and relative azimuthal angle (Δϕ\Delta \phi), for various multiplicity and transverse momentum (pTp_\mathrm{T}) intervals. A multiplicity dependence of the balance function is observed in Δη\Delta \eta and Δϕ\Delta \phi for both systems. The width of the balance functions decreases towards high-multiplicity collisions in the momentum region <\lt2 GeV, for pPb and PbPb results. No multiplicity dependence is observed at higher transverse momentum. The data are compared with HYDJET, HIJING and AMPT generator predictions, none of which capture completely the multiplicity dependence seen in the data

    Measurement of multidifferential cross sections for dijet production in proton-proton collisions at s\sqrt{s} = 13 TeV

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    International audienceA measurement of the dijet production cross section is reported based on proton-proton collision data collected in 2016 at s\sqrt{s} = 13 TeV by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of up to 36.3 fb1^{-1}. Jets are reconstructed with the anti-kTk_\mathrm{T} algorithm for distance parameters of RR = 0.4 and 0.8. Cross sections are measured double-differentially (2D) as a function of the largest absolute rapidity ymax\lvert y_\text{max}\rvert of the two jets with the highest transverse momenta pTp_\mathrm{T} and their invariant mass m1,2m_{1,2}, and triple-differentially (3D) as a function of the rapidity separation yy^*, the total boost yby_\mathrm{b}, and either m1,2m_{1,2} or the average pTp_\mathrm{T} of the two jets. The cross sections are unfolded to correct for detector effects and are compared with fixed-order calculations derived at next-to-next-to-leading order in perturbative quantum chromodynamics. The impact of the measurements on the parton distribution functions and the strong coupling constant at the mass of the Z boson is investigated, yielding a value of αS\alpha_\mathrm{S} = 0.1179 ±\pm 0.0019

    Multiplicity and transverse momentum dependence of charge-balance functions in pPb and PbPb collisions at LHC energies

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    International audienceMeasurements of the charge-dependent two-particle angular correlation function in proton-lead (pPb) collisions at a nucleon-nucleon center-of-mass energy of sNN\sqrt{s_\mathrm{NN}} = 8.16 TeV and lead-lead (PbPb) collisions atsNN\sqrt{s_\mathrm{NN}} = 5.02 TeV are reported. The pPb and PbPb datasets correspond to integrated luminosities of 186\nbinv and 0.607 nb1^{-1}, respectively, and were collected using the CMS detector at the CERN LHC. The charge-dependent correlations are characterized by balance functions of same- and opposite-sign particle pairs. The balance functions, which contain information about the creation time of charged particle pairs and the development of collectivity, are studied as functions of relative pseudorapidity (Δη\Delta \eta) and relative azimuthal angle (Δϕ\Delta \phi), for various multiplicity and transverse momentum (pTp_\mathrm{T}) intervals. A multiplicity dependence of the balance function is observed in Δη\Delta \eta and Δϕ\Delta \phi for both systems. The width of the balance functions decreases towards high-multiplicity collisions in the momentum region <\lt2 GeV, for pPb and PbPb results. No multiplicity dependence is observed at higher transverse momentum. The data are compared with HYDJET, HIJING and AMPT generator predictions, none of which capture completely the multiplicity dependence seen in the data

    Probing small Bjorken-xx nuclear gluonic structure via coherent J/ψ\psi photoproduction in ultraperipheral PbPb collisions at sNN\sqrt{s_\mathrm{NN}} = 5.02 TeV

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    International audienceQuasi-real photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The first measurement of the coherent J/ψ\psi photoproduction cross section in ultraperipheral lead-lead collisions is presented over a wide range of photon-nucleus center-of-mass energies per nucleon (WγNPb^\text{Pb}_{\gamma\text{N}}). Results are obtained using data at the nucleon-nucleon center-of-mass energy of 5.02 TeV collected by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 1.52 nb1^{-1}. The cross section is observed to rise rapidly at low WγNPb^\text{Pb}_{\gamma\text{N}}, and plateau above WγNPb^\text{Pb}_{\gamma\text{N}}\approx 40 GeV, up to 400 GeV, a new regime of small Bjorken-xx (\approx 6 ×\times 105^{-5}) gluons being probed in a heavy nucleus. The observed energy dependence is not predicted by current quantum chromodynamic models
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