Smoothness and long time existence for solutions of the Cahn-Hilliard equation on manifolds with conical singularities

We consider the Cahn-Hilliard equation on manifolds with conical singularities. For appropriate initial data we show that the solution exists in the maximal $L^q$-regularity space for all times and becomes instantaneously smooth in space and time, where the maximal $L^q$-regularity is obtained in the sense of Mellin-Sobolev spaces. Moreover, we provide precise information concerning the asymptotic behavior of the solution close to the conical tips in terms of the local geometry.Comment: 26 page

Using history to help refine international business theory: ownership advantages and the eclectic paradigm.

In John Dunning’s eclectic paradigm firms need to have ownership, location, and internalisation advantages in order to cross borders and engage in foreign direct investment. By drawing on historical evidence on the evolution of a group of leading marketing-based multinationals in consumer goods, this paper claims that, despite its richness, the eclectic paradigm, and in particular the concept of ‘ownership advantages’, needs to be revised and extended, to take into account different levels of institutional analysis. For the eclectic paradigm to give a rounded view of the internationalising firm it needs to acknowledge the critical importance of firm-specific ownership advantages such as the role of the entrepreneur

An instance of the MIKADO migration model

In this document, we briefly describe the main contribution to the deliverable on experimenting with the implementation of most of the calculi considered in the project. First, we describe how two well known calculi for mobile processes KLAIM and Dπ have been implemented on the top of IMC. We then describe the implementation of the MiKO programming language, an instance of the parametric calculus introduced in the WP1 with the TyCO calculus as the content of the membrane itself. After this, we outline the description of the implementation of the abstract machine for an instance of the Kell Calculus that dedicates particular attention to the proof of its correctness. Our presentation ends with a discussion of the problem of implementing security membranes on the top of an execution platform

In-situ electrochemical quantification of active sites in Fe-N/C non-precious metal catalysts

The economic viability of low temperature fuel cells as clean energy devices is enhanced by the development of inexpensive oxygen reduction reaction catalysts. Heat treated iron and nitrogen containing carbon based materials (Fe–N/C) have shown potential to replace expensive precious metals. Although significant improvements have recently been made, their activity and durability is still unsatisfactory. The further development and a rational design of these materials has stalled due to the lack of an in situ methodology to easily probe and quantify the active site. Here we demonstrate a protocol that allows the quantification of active centres, which operate under acidic conditions, by means of nitrite adsorption followed by reductive stripping, and show direct correlation to the catalytic activity. The method is demonstrated for two differently prepared materials. This approach may allow researchers to easily assess the active site density and turnover frequency of Fe–N/C catalysts

Evidence that the degree of band 3 phosphorylation modulates human erythrocytes nitric oxide efflux – in vitro model of hyperfibrinogenemia

© 2011 – IOS Press and the authors. All rights reservedRecent evidence has shown that plasma fibrinogen, a major cardiovascular risk factor, interacts with the erythrocyte membrane and acts to influence blood flow via erythrocyte nitric oxide (NO) modulation. In the present pioneer in-vitro study, whole blood samples were harvested from healthy subjects and aliquots were incubated in the absence (control aliquots) and presence of fibrinogen at different degrees of band 3 phosphorylation, and the levels of NO, nitrite, nitrate and S-nitroglutathione (GSNO) were determined. Hyperfibrinogenemia interferes with erythrocyte NO mobilization without changing its efflux in a way that seems to be dependent of the degree of band 3 phosphorylation. In presence of higher fibrinogen concentrations the NO efflux is reinforced when band 3 is phosphorylated (p < 0.001). Higher levels of nitrite, nitrate and GSNO were documented (p < 0.05). However, the mechanisms by which fibrinogen signalling modulates erythrocyte function remain to be clarified and are currently under study. These conditions may be considered an approach to be followed in blood storage for transfusions.This study was supported by grants from the FCT - Fundação para a Ciência e a Tecnologia (project reference PTDC/SAU-OSM/73449/2006