An exploration of intervention options to enhance the management of supply chain greenhouse gas emissions in the UK

The management of greenhouse gas emissions (GHGEs) within the supply chains of large organisations is receiving increasing attention as a way to achieve climate mitigation objectives. Climate mitigation policy for direct GHGEs and organisations' role in managing environmental impacts within supply chains is well covered in the literature. However, the targeting of indirect GHGE from the supply chain, and the intervention options that exist are still underdeveloped, especially in terms of information and informal based interventions, or support and capacity building approaches. Interview data was collected on the supply chain GHGE management actions of large supply chain leading organisations in the UK such as brand companies and public sector organisations. This is used to construct framework through which an initial and exploratory assessment of the efficacy and likely impacts of a range of interventions, designed to increase levels of supply chain GHGE management by supply chain leading organisations, is conducted. It is demonstrates that the management of indirect GHGEs could form an additional strategy for climate mitigation objectives, with information based options representing a good option for policymakers

Structural reliability analysis of multiple limit state functions using multi-input multi-output support vector machine

Selecting and using an appropriate structural reliability method is critical for the success of structural reliability analysis and reliability-based design optimization. However, most of existing structural reliability methods are developed and designed for a single limit state function and few methods can be used to simultaneously handle multiple limit state functions in a structural system when the failure probability of each limit state function is of interest, for example, in a reliability-based design optimization loop. This article presents a new method for structural reliability analysis with multiple limit state functions using support vector machine technique. A sole support vector machine surrogate model for all limit state functions is constructed by a multi-input multi-output support vector machine algorithm. Furthermore, this multi-input multi-output support vector machine surrogate model for all limit state functions is only trained from one data set with one calculation process, instead of constructing a series of standard support vector machine models which has one output only. Combining the multi-input multi-output support vector machine surrogate model with direct Monte Carlo simulation, the failure probability of the structural system as well as the failure probability of each limit state function corresponding to a failure mode in the structural system can be estimated. Two examples are used to demonstrate the accuracy and efficiency of the presented method

Constraints on Non-Newtonian Gravity from Recent Casimir Force Measurements

Corrections to Newton's gravitational law inspired by extra dimensional physics and by the exchange of light and massless elementary particles between the atoms of two macrobodies are considered. These corrections can be described by the potentials of Yukawa-type and by the power-type potentials with different powers. The strongest up to date constraints on the corrections to Newton's gravitational law are reviewed following from the E\"{o}tvos- and Cavendish-type experiments and from the measurements of the Casimir and van der Waals force. We show that the recent measurements of the Casimir force gave the possibility to strengthen the previously known constraints on the constants of hypothetical interactions up to several thousand times in a wide interaction range. Further strengthening is expected in near future that makes Casimir force measurements a prospective test for the predictions of fundamental physical theories.Comment: 20 pages, crckbked.cls is used, to be published in: Proceedings of the 18th Course of the School on Cosmology and Gravitation: The Gravitational Constant. Generalized Gravitational Theories and Experiments (30 April- 10 May 2003, Erice). Ed. by G. T. Gillies, V. N. Melnikov and V. de Sabbata, 20pp. (Kluwer, in print, 2003

Repair Wind Field of Oil Spill Regional Using SAR Data

In this paper, we compared the normalized radar cross section (NRCS) of the synthetic aperture radar in the cases of oil spill and clean sea areas with image samples and determined their thresholds of the NRCS of SAR. we used the NRCS of clean water from the adjacent patches spill area to replace NRCS of oil spill area and retrieval wind field by CMOD5.N and comparison of wind velocity mending of oil spill with Model data the root mean square of wind speed and wind direction inversion are 0.89m/s and 20.26 satisfactory results, respectively. Therefore, after the occurrence not large scale oil spill, the real wind field could be restored by this method.&nbsp

Characterization of intrinsic properties of cingulate pyramidal neurons in adult mice after nerve injury

The anterior cingulate cortex (ACC) is important for cognitive and sensory functions including memory and chronic pain. Glutamatergic excitatory synaptic transmission undergo long-term potentiation in ACC pyramidal cells after peripheral injury. Less information is available for the possible long-term changes in neuronal action potentials or intrinsic properties. In the present study, we characterized cingulate pyramidal cells in the layer II/III of the ACC in adult mice. We then examined possible long-term changes in intrinsic properties of the ACC pyramidal cells after peripheral nerve injury. In the control mice, we found that there are three major types of pyramidal cells according to their action potential firing pattern: (i) regular spiking (RS) cells (24.7%), intrinsic bursting (IB) cells (30.9%), and intermediate (IM) cells (44.4%). In a state of neuropathic pain, the population distribution (RS: 21.3%; IB: 31.2%; IM: 47.5%) and the single action potential properties of these three groups were indistinguishable from those in control mice. However, for repetitive action potentials, IM cells from neuropathic pain animals showed higher initial firing frequency with no change for the properties of RS and IB neurons from neuropathic pain mice. The present results provide the first evidence that, in addition to synaptic potentiation reported previously, peripheral nerve injury produces long-term plastic changes in the action potentials of cingulate pyramidal neurons in a cell type-specific manner

Mental Health Diagnoses and Utilization of VA Non-Mental Health Medical Services Among Returning Iraq and Afghanistan Veterans

Over 35% of returned Iraq and Afghanistan veterans in VA care have received mental health diagnoses; the most prevalent is post-traumatic stress disorder (PTSD). Little is known about these patients’ use of non-mental health medical services and the impact of mental disorders on utilization. To compare utilization across three groups of Iraq and Afghanistan veterans: those without mental disorders, those with mental disorders other than PTSD, and those with PTSD. National, descriptive study of 249,440 veterans newly utilizing VA healthcare between October 7, 2001 and March 31, 2007, followed until March 31, 2008. We used ICD9-CM diagnostic codes to classify mental health status. We compared utilization of outpatient non-mental health services, primary care, medical subspecialty, ancillary services, laboratory tests/diagnostic procedures, emergency services, and hospitalizations during veterans’ first year in VA care. Results were adjusted for demographics and military service and VA facility characteristics. Veterans with mental disorders had 42–146% greater utilization than those without mental disorders, depending on the service category (all P < 0.001). Those with PTSD had the highest utilization in all categories: 71–170% greater utilization than those without mental disorders (all P < 0.001). In adjusted analyses, compared with veterans without mental disorders, those with mental disorders other than PTSD had 55% higher utilization of all non-mental health outpatient services; those with PTSD had 91% higher utilization. Female sex and lower rank were also independently associated with greater utilization. Veterans with mental health diagnoses, particularly PTSD, utilize significantly more VA non-mental health medical services. As more veterans return home, we must ensure resources are allocated to meet their outpatient, inpatient, and emergency needs

International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe

In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors’ experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible

Degree of adaptive male mate choice is positively correlated with female quality variance

When the cost of reproduction for males and variance in female quality are high, males are predicted to show adaptive mate choice. Using Drosophila melanogaster, we test this prediction and show that sperm limited males preferentially mated with young and/or well fed females. The preferred females had higher reproductive output – direct evidence of adaptive precopulatory male mate choice. Our most striking finding is the strong positive correlation between the degree of mating bias showed by the males and the variance in the fitness of the females. We discuss the possible mechanism for such adaptive male mate choice and propose that such choice has important consequences with respect to the existing understanding of the mating system and the evolution of aging