Evaluating the Rationale for Folding Wing Tips Comparing the Exergy and Breguet Approaches

The design and development processes for future aircraft aims to address the environmental and efficiency challenges needed to facilitate the engineering of concepts that are far more integrated and require a multidisciplinary approach. This study investigates the benefit of incorporating span extension wing tips onto future aircraft configurations as a method of providing improved aerodynamic efficiency, whilst allowing the extension to fold on the ground to meet airport gate size constraints. Although the actuated wing tips are not studied in detail, the focus of this study is to compare two different methods of analysis that can be used to identify the benefit and limitations of adding such devices. The two methods considered are a quasi-steady implicit energy analysis based on the Breguet Range Equation and an explicit energy analysis based on the first and second laws of thermodynamics known as Exergy Analysis. It has been found that both methods provide agreeable results and have individual merits. The Breguet Range Equation can provide quick results in early design, whilst the Exergy Analysis has been found to be far more extensive and allows the complete dynamic behaviour of the aircraft to be assessed through a single metric. Hence, allowing comparison of losses from multiple subsystems

Exploring the contribution of exposure heterogeneity to the the cessation of the 2014 Ebola epidemic

<div><p>The unexpected early cessation of the recent West Africa Ebola outbreak demonstrated shortcomings of popular forecasting approaches and has not been fully understood yet. A popular hypothesis is that public health interventions mitigated the spread, such as ETUs and safe burials. We investigate whether risk heterogeneity within the population could serve as an alternative explanation. We introduce a model for spread in heterogeneous host population that is particularly well suited for early predictions due to its simplicity and ease of application. Furthermore, we explore the conditions under which the observed epidemic trajectory can be explained without taking into account the effect of public health interventions. While the obtained fits closely match the total case count time series, closer inspection of sub-population results made us conclude that risk heterogeneity is unlikely to fully explain the early cessation of Ebola; other factors such as behavioral changes and other interventions likely played a major role. More accurate predictions in a future scenario require models that allow for early sub-exponential growth, as well as access to additional data on patient occupation (risk level) and location, to allow identify local phenomena that influence spreading behavior.</p></div

Maternal anaemia and its impact on perinatal outcome in a tertiary care hospital in Pakistan

Maternal anaemia is a common problem in pregnancy, particularly in developing countries. We investigated the relationship between maternal anaemia and perinatal outcome in a cohort of 629 pregnant women from October 2001 to 2002. Of these, 313 were anaemic (haemoglobin \u3c 11 g/L). Perinatal outcomes included preterm delivery, low birth weight, intrauterine growth retardation, perinatal death, low Apgar scores and intrauterine fetal death. Univariate and multivariate analyses were performed. The risk of preterm delivery and low birth weight among the anaemic women was 4 and 1.9 times more respectively than the non-anaemic women. The neonates of anaemic women also had 1.8 times increased risk having low Apgar scores at 1 minute and there was a 3.7 greater risk of intrauterine fetal death among the anaemic women than the non-anaemic women

Multi-objective optimal longitudinal flight control system design for large flexible transport aircraft

This paper presents a multi-objective evolutionary algorithm design of a longitudinal optimal controller for a large flexible transport aircraft. The algorithm uses a mixed optimization approach based on a combination of Linear Quadratic Regulator (LQR) control and a Multi-Objective Genetic Algorithm (MOGA) to search over a set of possible weighting function structures and parameter values in order to satisfy a number of conflicting design criteria. The proposed approach offers a number of potential optimal solutions lying on or near the Pareto optimal front of competing objectives. The approach is explained in this paper and some results are presented

Adopting exergy analysis for use in aerospace

Thermodynamic analysis methods, based on an exergy metric, have been developed to improve system efficiency of traditional heat driven systems such as ground based power plants and aircraft propulsion systems. However, in more recent years interest in the topic has broadened to include applying these second law methods to the field of aerodynamics and complete aerospace vehicles. Work to date is based on highly simplified structures, but such a method could be shown to have benefit to the highly conservative and risk averse commercial aerospace sector. This review justifies how thermodynamic exergy analysis has the potential to facilitate a breakthrough in the optimization of aerospace vehicles based on a system of energy systems, through studying the exergy-based multidisciplinary design of future flight vehicles

Studies on drought tolerance in maize inbred lines using morphological and molecular approaches

A set of hundred homozygous maize inbred lines were analyzed for drought toleranceby studying twenty-four traits related to maturity, morphological, physiological, yield, quality and few root traits. Evaluation confirmed a wide range of variability revealing significant response of main effects (lines, irrigations and years and their respective digenic and trigenic interactions). These lines were subjected to different stress regimes over years leading to identification of fifteen elite lines which performed well under droughtstress showing inbuilt drought tolerance. A set of 32 SSR markers, having genome-wide coverage, were chosen for genotyping the inbred lines. These markers generated a total of 239 polymorphic alleles with an average of 7.47 alleles per locus. The minimum and maximum PIC value was 0.886 and 0.608 with a mean of 0.782. The coefficient of genetic dissimilarity ranged from 0.215 to 0.148. DARwin derived cluster analysis grouped 15 elite maize lines in three major clusters with five lines each in cluster-III and II and four lines in cluster-I with KDM-361A as root. Molecular diversity however, confirmed diverse genetic nature of six lines (KDM-372, KDM-343A, KDM-331, KDM-961, KDM-1051 and KDM-1156) showing drought tolerance. Exploitation of identified elite lines in a crossing program involving all possible combinations would help to develop hybrids with inbuilt mechanism to drought tolerance. Markers viz., umc -1766, umc-1478 and phi-061 recorded PIC >8 and alleles per locus more than 9 and therefore, discriminated the set of lines more efficiently. Genotyping data complemented by morpho- hysiological parameters were used to identify a number of pair-wise combinations for the development of mapping population segregating for drought tolerance and potential heterotic pairs for the development of drought tolerant hybrids.

Prevalence of Cancer in Adult Patients with Atopic Dermatitis:A Nationwide Study

Abstract is missing (Short communication