Review on Workplace Spirituality

The Corona Pandemic was a time to learn and grow for people and organizations all around the world.  The organizations understood the importance of efficient and innovative management techniques. Certain organizations were in fact thriving, with customers and employees valuing the organizations. despite the lower sales and insufficiency of funds. they were ready to forfeit a discount, pay more than the actual price and share their income to pool resources for the organization. Researchers found that organizational commitment was more in such organizations. On further analysing the reviews of researchers, it was observed that organizational spirituality started from an individual, usually the leader, and quickly became the organization’s culture. There was an increase in workplace joy, health, commitment, creativity, security and a feeling of home within the organization. In this paper, we have attempted to summarize the concept of workplace spirituality from various original papers which were published on ‘Web of science’ database. The idea is to have a complete and concise understanding of the term workplace spirituality

Clinicopathological Study of Ovarian Germ Cell Tumours in Tertiary Care Hospital, Tamil Nadu, India: A cross-sectional Study

Introduction: Ovarian germ cell tumours are a heterogeneous group of neoplasms derived from primitive germ cells of the embryonic gonad, either directly or indirectly. They can be classified as benign and malignant, with slow and rapid growth and spread, respectively. Benign ovarian germ cell tumours are common, while malignant tumours are rare and account for about 2.6% of all ovarian malignancies. They are more common in the second and third decades of life and typically present with abdominal mass, pain, and elevated serum tumour markers, which aid in primary diagnosis and follow-up. Aim: To analyse the distribution of germ cell tumours in the ovary in relation to age, parity, mode of presentation, biochemical markers, histomorphological patterns, and immunohistochemical markers. Materials and Methods: This cross-sectional study was conducted at Department of Pathology, Sree Balaji Medical College, Hospital and Research Institute, Chromepet, Chennai, Tamil Nadu, India. The study involved 86 ovarian specimens, of which 25 were germ cell tumours. Complete clinical history, radiological findings, and pre-operative laboratory test values were recorded. The ovarian specimens were carefully examined for gross appearances, fixed in 10% neutral buffered formalin for 24-48 hours, and subjected to histopathological processing, routine and special staining, and immunohistochemical study after observing the different morphological patterns of the ovarian specimens received. Results: The age range of presentation was between 14 years and 58 years. Seventeen patients were parous (14 benign and 3 malignant), and eight (5 benign and 3 malignant) were nulliparous. Abdominal mass and abdominal pain were the most common modes of presentation. Out of 25 germ cell tumours, 19 were benign cystic mature teratomas, 2 were immature teratomas, 1 was a yolk sac tumour, 2 were dysgerminomas, and 1 was a carcinoid tumour, with 6 being malignant and 19 being benign tumours. Among the 6 malignant ovarian tumours, 5 cases had raised serum tumour markers {cancer antigen-125 (CA-125), Alpha-Fetoprotein (AFP)} pre-operatively, and the levels reduced and became normal after surgery. Among the 2 cases of immature teratoma, one was Grade-II and the other was Grade-III. For one case with mixed tumour components, CD-30 and α-fetoprotein immunohistochemical markers were performed, showing negative and positive results, respectively. Conclusion: Among the histopathological subtypes, benign cystic teratomas were the most common ovarian germ cell tumours in this study. Both benign and malignant tumours presented with abdominal pain and abdominal mass. Most of the tumours were diagnosed between the ages of 21 and 40 years. In this study, α-fetoprotein immunohistochemical marker showed strong positivity, confirming a single tumour component

Green synthesis of novel pyrazoline carbothioamides: A potent antimicrobial and antioxidant agents

Oxidative-stress induces inflammatory diseases caused by drug-resistant microbial stains are on the increase necessitating the invention of novel small-molecules for intervention therapy. In search of new small molecules of potent antioxidant properties, the current study was undertaken to synthesize pyrazoles and study their radical scavenging abilities. An efficient and accessible green protocol for the synthesis of thiophene-pyrazole hybrids through the 3 + 2 annulation, the reaction of chalcones 3(a-k) with thiosemicarbazide hydrochloride 4 in freshly prepared aqueous citrus extract medium produced the thiophene tethered pyrazoline carbothioamides 5(a-k) in good yields. Structure proofs of new pyrazoles provided by spectroscopic studies and elemental analysis. Furthermore, preliminary assessment of the antimicrobial, DPPH, and hydroxyl radical scavenging activities of the compounds shows that, compounds 5c and 5k have excellent antimicrobial activities, and 5a, 5b, 5c, 5d, 5g, and 5k exhibited excellent DPPH, and hydroxyl radical scavenging abilities

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Not AvailableThe cyclic guanomonophosphate (cGMP) dependent protein kinase (PKG) plays an important role in the food related behaviours of several insect species. Here we report the influence of cGMP dependent PKG on prey consumption of adult predatory coccinellid, Cryptolaemus montrouzieri Mulsant (Coleoptera: Coccinellidae). The oral cGMP treatment (which increases PKG activity) enhanced the feeding potential of C. montrouzieri. The good foragers responded more positively to the cGMP treatment compared to the poor foragers. The cGMP levels estimated through ELISA were significantly (P < 0.001) high in the digestive tissues of unfed as well as cGMP treated C. montrouzieri compared to normal fed beetles. This finding suggests that cGMP is involved in the higher feeding rates of C. montrouzieri and the partial foraging gene (~455 bp) which encodes the cGMP dependent PKG was isolated from genomic DNA of C. montrouzieri using gene specific primers.Not Availabl