Internationalization Of Management Buyouts

Multivariate statistical analysis is utilized to explore the association between firm strategies, contributions made by venture capitalists and incentives for owners and employees and three exporting variables in a stratified random sample of 147 management buyouts and buyins. Firms focusing upon a diversified product/ service range and/or advertising were significantly more likely to be exporters. Firms focusing upon product/ service quality and financial efficiency and those with high proportions of employees receiving performance related pay were significantly less likely to be exporters. Manufacturing firms and firms focusing upon a diversified product/ service range and/or advertising were significantly more likely to report high percentages of sales exported. Variations in the proportion of sales exported over time were associated with strategies focused upon product/service quality and a diversified product/ service range

The characterisation of diesel nozzle flow using high speed imaging of elastic light scattering

Two identical, conventional six-hole, valve-covered orifice (VCO) diesel injectors have been modified in order to provide optical access to the region below the needle, and the nozzle-flow passages. This has been achieved through the removal of the metal tips, and their replacement with transparent acrylic tips of identical geometry. These two identical injectors were employed in order to offer comparability between the measurements. One of them had a dark, anodised inner surface at the base, while the other had a silvered inner surface at the base. Elastic scattering of incident white light from the internal cavitating flow inside the nozzle holes of the optically accessible diesel injector tips was captured on a high-speed electronic camera. The optical image data was obtained for three injector rail pressures ranging from 200 bar to 400 bar, and for five diesel fuels of varying density, viscosity, and distillation profile, in order to identify variations in cavitation flow behaviour inside the nozzle hole passages. A set of mean time-resolved diesel fuel flow images were obtained from 30 successive fuel injection pulses, for each operating condition, for each injector. The mean cavitation image occurring in the nozzle holes was converted to the mean proportion of nozzle hole area producing cavitation-induced optical scattering. The mean normalised area images were then analysed, and were able to demonstrate the anticipated inverse relationship between injected fuel mass and cavitation volume fraction (indicated by mean normalised area), and the effect of fuel viscosity and distillation profile on cavitation volume fraction (again indicated by mean normalised area)

Little evidence for association between the TGFBR1*6A variant and colorectal cancer: a family-based association study on non-syndromic family members from Australia and Spain.

Genome-wide linkage studies have identified the 9q22 chromosomal region as linked with colorectal cancer (CRC) predisposition. A candidate gene in this region is transforming growth factor beta receptor 1 (TGFBR1). Investigation of TGFBR1 has focused on the common genetic variant rs11466445, a short exonic deletion of nine base pairs which results in truncation of a stretch of nine alanine residues to six alanine residues in the gene product. While the six alanine (*6A) allele has been reported to be associated with increased risk of CRC in some population based study groups this association remains the subject of robust debate. To date, reports have been limited to population-based case-control association studies, or case-control studies of CRC families selecting one affected individual per family. No study has yet taken advantage of all the genetic information provided by multiplex CRC families. Methods: We have tested for an association between rs11466445 and risk of CRC using several family-based statistical tests in a new study group comprising members of non-syndromic high risk CRC families sourced from three familial cancer centres, two in Australia and one in Spain. Results: We report a finding of a nominally significant result using the pedigree-based association test approach (PBAT; p = 0.028), while other family-based tests were non-significant, but with a p-value < 0.10 in each instance. These other tests included the Generalised Disequilibrium Test (GDT; p = 0.085), parent of origin GDT Generalised Disequilibrium Test (GDT-PO; p = 0.081) and empirical Family-Based Association Test (FBAT; p = 0.096, additive model). Related-person case-control testing using the 'More Powerful' Quasi-Likelihood Score Test did not provide any evidence for association (M-QL5; p = 0.41). Conclusions: After conservatively taking into account considerations for multiple hypothesis testing, we find little evidence for an association between the TGFBR1*6A allele and CRC risk in these families. The weak support for an increase in risk in CRC predisposed families is in agreement with recent meta-analyses of case-control studies, which estimate only a modest increase in sporadic CRC risk among 6*A allele carriers

Little evidence for association between the TGFBR1*6A variant and colorectal cancer: a family-based association study on non-syndromic family members from Australia and Spain

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Genome-wide linkage studies have identified the 9q22 chromosomal region as linked with colorectal cancer (CRC) predisposition. A candidate gene in this region is transforming growth factor β receptor 1 (TGFBR1). Investigation of TGFBR1 has focused on the common genetic variant rs11466445, a short exonic deletion of nine base pairs which results in truncation of a stretch of nine alanine residues to six alanine residues in the gene product. While the six alanine (*6A) allele has been reported to be associated with increased risk of CRC in some population based study groups this association remains the subject of robust debate. To date, reports have been limited to population-based case–control association studies, or case–control studies of CRC families selecting one affected individual per family. No study has yet taken advantage of all the genetic information provided by multiplex CRC families

Evaluating a financial service opportunity via judgemental modelling

The financial services market is currently undergoing tremendous change, due to the twin influences of developments in the field of Electronic Data Interchange (EDI) and changes in the legislation determining how banks will be allowed to operate after 1992. Describes research whose objective was to evaluate the viability of introducing a new service to handle cross-border payments, undertaken for a large multinational bank, and focused on respondents from a variety of firms within the European Community. Uses a combination of a PC-based judgemental modelling package and in-depth interviews to develop a clear understanding of the needs of both the originators′ and the vendors′ requirements. Although based on a relatively small sample, the detailed findings permit development of an effective approach to segmenting the market for the particular service

A prediction model for colon cancer surveillance data

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/112258/1/sim6500-sup-0001-Supplementary1.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/112258/2/sim6500.pd

SiO masers in TX Cam: Simultaneous VLBA observations of two 43 GHz masers at four epochs

We present the results of simultaneous high resolution observations of v=1 and v=2, J=1-0 SiO masers toward TX Cam at four epochs covering a stellar cycle. Near maser maximum (Epochs III and IV), the individual components of both masers are distributed in ring-like structures but the ring is severely disrupted near stellar maser minimum (Epochs I and II). In Epochs III and IV there is a large overlap between the radii at which the two maser transitions occur. However in both epochs the average radius of the v=2 maser ring is smaller than for the v=1 maser ring, the difference being larger for Epoch IV. The observed relative ring radii in the two transitions, and the trends on the ring thickness, are close to those predicted by the model of Humphreys et al. (\cite{humphreys02}). In many individual features there is an almost exact overlap in space and velocity of emission from the two transitions, arguing against pure radiative pumping. At both Epochs III and IV in many spectral features only 50% of the flux density is recovered in our images, implying significant smooth maser structure. For both transitions we find that red- and blue-shifted masers occur in all parts of the rings, with relatively few masers at the systemic velocity. Thus there is no evidence for rotation, although the blue-shifted masers are somewhat more prominent to the west. At all four epochs red-shifted components are generally brighter than blue-shifted ones. At Epochs III and IV, we see many filamentary or spoke-like features in both v=1 and v=2 masers, especially in the red-shifted gas. These spokes show systematic velocity gradients consistent with a decelerating outward flow with increasing radius. We outline a possible model to explain why, given the presence of these spokes, there is a deficit of maser features at the systemic velocity.Comment: 15 pages, 10 figs, accepted to A&A, Abstract is reduced (see the paper for full length

Sensitive VLBI Studies of the OH Megamaser Emission from IRAS 17208-0014

We present phase-referenced VLBI results on the radio continuum and the OH 18 cm megamaser emission from the Ultra-Luminous Infrared Galaxy, IRAS 17208--0014. The observations were carried out at 1599 MHz using the Very Long Baseline Array, the phased VLA, and the Green Bank Telescope. The highest resolution radio continuum results show several compact sources with brightness temperatures on the order of $10^{6}$ K. These sources are more likely to be clustered supernova remnants and/or luminous radio supernovae. However, the agreement between the number of observed and expected compact sources above the 5 $\sigma$ level supports the possibility that each one of the compact sources could be dominated by a recently detonated luminous radio supernova. The continuum results suggest that there is no radio-loud AGN in the nuclear region of this galaxy. The OH 18 cm megamaser emission in IRAS 17208--0014 is detected at various angular resolutions. It has an extent of $170 \times 110$ pc, and is mostly localized in two regions separated by 61 pc. The structure and dynamics of the maser emission seem to be consistent with a clumpy, rotating, ring-like geometry, with the two dominant maser regions marking the tangential points of the proposed rotating-ring distribution. Assuming Keplerian motion for the rotating maser ring, the enclosed dynamical mass and the mass density within a radius of 30.5 pc, are about {$3 \times 10^7 ({\rm sin}^{-2}i) M{_\odot}$}, and $281 ({\rm sin}^{-2} i) M{_\odot} {\rm pc}^{-3}$, respectively.Comment: 8 pages, 5 figures. ApJ Accepte