Estudo de pacientes com história de reações sistêmicas a himenópteDa Rosem Florianópolis.

Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis, 199

Databasing Molecular Neuroimaging

Molecular neuroimaging Most molecular imaging studies relies on analysis of values from brain regions and report descriptive statistics for these values. There are two significant difficulties when comparing molecular neuroimaging studies: 1. Regions differ between studies: E.g., some include values for “temporal cortex ” others do not. 2. Measured and reported values differ between studies and they are not comparable: Tracers and receptors; transport rates (e.g., K1), distribution volume, binding potentials; different methods to compute the values

Anatomic Thoracoscopic Repair of Esophageal Atresia

Background: The thoracoscopic approach to repair esophageal atresia (EA) with tracheoesophageal fistula (TEF) provides excellent view, allowing the most skillful surgeons to spare the azygos vein by performing the esophageal anastomosis over (on the right side) the azygos vein. Seeking the most anatomic repair, we started to perform the esophageal anastomosis underneath (on the left side) the azygos vein: anatomic thoracoscopic repair of esophageal atresia (ATREA). We aim to compare results of ATREA with the classic thoracoscopic repair. Methods: During the last 4 years, in our center, all infants with EA with distal TEF were operated by thoracoscopy sparing the azygos vein. According to the surgical technique, two groups were created: Group A-treated with ATREA and Group B-treated with classic thoracoscopic repair over (on the right side) the azygos vein. We retrospectively collected data regarding features of the newborn (gestational age, gender, karyotype changes, associated anomalies, birth weight), surgery (operative technique, operative time, and surgical complications), hospitalization (duration of mechanical ventilation, thoracic drainage, time for the first feeding, time of admission, and early complications) and follow-up [tracheomalacia, gastroesophageal reflux disease (GERD), anastomotic stricture, recurrence of fistula]. results: Group A had seven newborns and Group B had four newborns. There were no statistically significant differences between both groups concerning the evaluated variables on surgery, hospitalization, and follow-up. Nevertheless, in Group A, there was an infant with a right aortic arch where ATREA was particularly useful as it avoided that the azygos vein and the aortic arch were left compressed in between the esophagus and trachea. Postoperatively, one patient of Group B had a major anastomotic leak with empyema requiring surgical re-intervention. During follow-up, anastomotic stricture requiring esophageal dilation occurred with similar rates in both groups. In Group B, one patient had severe and symptomatic tracheomalacia requiring aortopexy and severe GERD requiring fundoplication. No patients developed recurrent fistula. conclusion: The ATREA is feasible in the great majority of patients with EA with TEF without compromising long-term results and might be particularly useful for those infants with malformations of the cardiac venous return vessels and/or major aortic malformations.projects NORTE-01-0246-FEDER-000012, NORTE-01-0145-FEDER-000013, and NORTE-01-0145-FEDER-000023, supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER)info:eu-repo/semantics/publishedVersio

Evaluation of government equity participation in the minerals sector: a case study of Tanzania from 1996-2015

A research report submitted to the Faculty of Engineering and the Built Environment, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Science in Engineering, Johannesburg, 2018Government’s equity role in the minerals sector is one of the nationalist measures to have a greater control and management of mineral resources in a country. This study looks into evaluation of government equity participation in the minerals sector in which Tanzania is a case study from 1996 to 2015. Amongst the objectives of the study was the determination of the number of mineral rights, minimum allowable exploration expenditures in Prospecting Licences (PLs) and forms of equity role of Tanzanian government in the minerals sector with their projects. Methodology of research included going through the background of the study, literature review, collection of data and analysis of PLs, Mining Licences (MLs) and Special Mining Licences (SMLs) to mention a few. Some of results of the research have indicated that, there were106 mineral rights (97 PLs, 3 MLs and 6 SMLs). State Mining Corporation (STAMICO) and National Development Corporation (NDC) as parastatals and Treasury Registrar (TR), a government agent owned these mineral rights on the behalf of the Tanzanian government (TZGT). It was also found that there are three forms of equity role namely: carried equity, paid equity and free carry equity that were applicable in prospecting, medium and large scale mining in the country. Carried equity role was applied in 56 PLs, 3 medium scale mines and 4 large scale mines. The three medium scale mines in which carried equity role was applied were Merelani TanzaniteOne Mining Ltd (MTM), Kigosi Gold Mine (KGM) and Ngaka Coal Mine (NCM). On the other hand, carried equity role was also exercised in the four large scale mines namely: Buckreef Gold Mine (BKGM), Liganga Iron ore Mine (LIOM), Mchuchuma Coal Mine (MCM) and Williamson Diamonds Mine (WDM). Paid equity role was applied in 41 PLs and 2 large scale mines namely: Kiwira Coal Mine (KCM and Stamigold Biharamulo Mine (SBM). Although the Mining Act, 2010 defines the free carry equity in terms of the free carried interest (FCI), this equity role approach is not yet in practice in Tanzania. In 2014, TZGT planned to execute free carry equity in Nachu Graphite Project (NGRP) and Mkuju River Uranium Project (MRUP). Negotiations for having free carried interest (FCI) for each project were conducted between the TZGT and project’s owners from 2014 to 2015. In 2015, negotiations between parties were concluded iii unsuccessful, as parties could not reach consensus on FCIs. This consequently impeded signing of minerals development agreements (MDAs), which also limited execution of the free carry equity role by the government. Research revealed also that there were a number of challenges or shortfalls faced by the TZGT equity role strategy in the mineral sector. One of the major challenge was the secrecy in agreements and contracts entered between the TZGT and the private sector investors through various business ownerships and mineral developments pertaining the minerals sector. This in turn resulted to non-transparency and unaccountability in the prospecting and mining, which risked TZGT entering unfair and/or objectionable agreements or contracts. Some of the conclusions were counter productivity of TZGT equity role and inadequacy of financial benefits realised from the strategy. These conclusions demonstrated ineffective performance of equity role of the Tanzanian government in prospecting, medium and large scale mining. Recommendations given in this research study report, is that, the government should review the Mining Act and Regulations of 2010. This is to allow the government incorporation of Parliament in the handling of agreements or contracts in the minerals sector. Moreover, proposition of fixed rates of FCI is among areas of future research work.XL201

Forest-derived lignin biomarkers in an Australian oxisol decrease substantially after 90 years of pasture

The dynamics of soil organic matter are a key factor in controlling the terrestrial carbon cycle. Compound specific stable carbon isotope analysis has given new insight in to the stability of individual organic molecules in soil. For lignin, one of the major plant compounds, available data suggest the existence of both a labile (turnover time <1 year) and a relatively stable (turnover time in the range of decades) pool. However, these data derive almost exclusively from agricultural soils in temperate climates. In order to extend the range both in ecosystem type and observed time span, we analysed a pasture soil in subtropical Australia that had experienced a land use change from rainforest 90 years earlier. We determined the concentration and isotopic signature of lignin biomarkers and compared them to those in an existing rainforest soil nearby and to samples of the respective vegetation. The land use change shifted both the relative abundance of lignin biomarkers and their isotopic signatures. In particular, the isotope data indicate that the pasture soil contains only small proportions of inherited rainforest-derived lignin biomarkers, which are mostly close to or below detection limit. These drastic changes in biomarker composition indicate that the original lignin structure had little chance to persist in this soil over a century. Thus, the stable soil organic carbon identified an earlier study of this soil is probably highly altered material and lignin biomarkers are not a suitable proxy of this stable carbon

Optimal Sufficient Requirements on the Embedded Ising Problem in Polynomial Time

One of the central applications for quantum annealers is to find the solutions of Ising problems. Suitable Ising problems, however, need to be formulated such that they, on the one hand, respect the specific restrictions of the hardware and, on the other hand, represent the original problems which shall actually be solved. We evaluate sufficient requirements on such an embedded Ising problem analytically and transform them into a linear optimization problem. With an objective function aiming to minimize the maximal absolute problem parameter, the precision issues of the annealers are addressed. Due to the redundancy of several constraints, we can show that the formally exponentially large optimization problem can be reduced and finally solved in polynomial time for the standard embedding setting where the embedded vertices induce trees. This allows to formulate provably equivalent embedded Ising problems in a practical setup.Comment: 34 pages, 3 figure