158 research outputs found

    Optical bus of centralized relay protection and automation system of medium voltage switchgear for data collection and transmission

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    The article deals with the system of information collection and transfer from a centralized relay protection and automation system for medium voltage electrical units based on a passive optical bus. The issues of electromagnetic compatibility of technical devices are also considered, and the intensity of electromagnetic interference is calculated in the distribution center of medium voltage. Since the electric power industry objects are characterized by a complex electromagnetic environment, including a significant adverse effect on the reliability and full functionality of modern microprocessor relay protection and anti-emergency automatic systems, the solution is considered for a centralized relay protection and automation system based on xPON passive optical network technology.Key words: centralized system of relay protection and automation, signaling and measurements; distribution point of medium voltage; medium voltage distribution network; electromagnetic interference; conductive low-frequency interference; conductive highfrequency interference; IEC 61850; IEC 61000-2-5-195; IEC 61000-4; Degree of electromagnetic compatibility intensity

    Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells

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    Glucose transport in adipose cells is regulated by changing the distribution of glucose transporter 4 (GLUT4) between the cell interior and the plasma membrane (PM). Insulin shifts this distribution by augmenting the rate of exocytosis of specialized GLUT4 vesicles. We applied time-lapse total internal reflection fluorescence microscopy to dissect intermediates of this GLUT4 translocation in rat adipose cells in primary culture. Without insulin, GLUT4 vesicles rapidly moved along a microtubule network covering the entire PM, periodically stopping, most often just briefly, by loosely tethering to the PM. Insulin halted this traffic by tightly tethering vesicles to the PM where they formed clusters and slowly fused to the PM. This slow release of GLUT4 determined the overall increase of the PM GLUT4. Thus, insulin initially recruits GLUT4 sequestered in mobile vesicles near the PM. It is likely that the primary mechanism of insulin action in GLUT4 translocation is to stimulate tethering and fusion of trafficking vesicles to specific fusion sites in the PM

    Study of high temperature and high density plasmoids in axially symmetrical magnetic fields

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    Within the framework of an Institutional Partnership of the Alexander von Humboldt Foundation, the Budker Institute of Nuclear Physics Novisibirsk (BINP) and Forschungszentrum Dresden-Rossendorf worked together in a joint project devoted to the research at the coupled GDT-SHIP facility of the BINP with the focus on the study of plasma phenomena within the SHIP mirror section. The project began at July 1st, 2005 and ended on August 30th, 2008. It included work packages of significant theoretical, computational and analyzing investigations. The focus of this final report is on the presentation of results achieved whereas the work that was done is described briefly only. Chapter 2 illustrates the GDT-SHIP facility and describes shortly the planned topics of the SHIP plasma research. Chapter 3 explains the main extensions and modifications of the Integrated Transport Code System (ITCS) which were necessary for the calculations of the fast ion and neutral gas particle fields in SHIP, describes briefly the scheme of computations and presents significant results of pre-calculations from which conclusions were drawn regarding the experimental program of SHIP. In chapter 4, the theoretical and computational investigations of self-organizing processes in two-component plasmas of the GDT-SHIP device are explained and the results hitherto achieved are presented. In chapter 5, significant results of several experiments with moderate and with enhanced plasma parameters are presented and compared with computational results obtained with the ITCS. Preparing neutron measurements which are planned for neutron producing experiments with deuterium injection, Monte Carlo neutron transport calculations with the MCNP code were also carried out. The results are presented. Finally, from the results obtained within the joint research project important conclusions are drawn in chapter 6

    Современная роль и перспективы электрофизиологических методов исследования в офтальмологии. Обзор литературы

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    Electrophysiological research today remains an important method for the objective assessment of the functional state of the components of the visual analyzer. There are methods, for example, OCT, that can objectively assess the structural and anatomical integrity of the retina, however, only indirectly shows functional activity. The undoubted advantage of EFR is the ability, excluding the subjectivity of the subject, to perform a functional topographic assessment of the malfunction of all systems of the visual analyzer. Private electrophysiology of the vision organ is represented by a variety of methods for recording the electrobiological activity of the cells of the visual analyzer: ERG, EOG, VEP, mfERG (multifocal electroretinography), and each option is directed to a separate part of it, therefore, to complete the picture, in particular in research works on animal models may use several techniques. In general, the limitation of EFR is its complexity and many confounding factors that can affect the result, ranging from stimulation parameters to the state of the patient himself. At the same time, the main area of prospective use of electrophysiological research is differential diagnosis, preclinical toxicology and scientific and experimental models. However, in recent decades, the active introduction of registration methods, including the appearance of multifocal electroretinography, as well as changes in the conditions of electrophysiological studies, open up new possibilities for the future evolution of the method. Classical methods for evaluating EFR data, taking into account the growth of data flow, do not provide detailed qualitative and quantitative information about the state of the visual analyzer. This leaves the possibility and the need for the study, optimization and algorithmization of the assessment data of the differentiated criteria inherent for a particular ocular pathology. EFRs require simpler and more adapted protocols for clinical practice, allowing a strictly differentiated approach to the smallest anatomical and functional changes, based on open databases and modern adaptation based on artificial intelligence. © 2020 Ophthalmology Publishing Group. All rights reserved
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