46 research outputs found

    Data for wetlandscapes and their changes around the world

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    Geography and associated hydrological, hydroclimate and land-use conditions and their changes determine the states and dynamics of wetlands and their ecosystem services. The influences of these controls are not limited to just the local scale of each individual wetland but extend over larger landscape areas that integrate multiple wetlands and their total hydrological catchment – the wetlandscape. However, the data and knowledge of conditions and changes over entire wetlandscapes are still scarce, limiting the capacity to accurately understand and manage critical wetland ecosystems and their services under global change. We present a new Wetlandscape Change Information Database (WetCID), consisting of geographic, hydrological, hydroclimate and land-use information and data for 27 wetlandscapes around the world. This combines survey-based local information with geographic shapefiles and gridded datasets of large-scale hydroclimate and land-use conditions and their changes over whole wetlandscapes. Temporally, WetCID contains 30-year time series of data for mean monthly precipitation and temperature and annual land-use conditions. The survey-based site information includes local knowledge on the wetlands, hydrology, hydroclimate and land uses within each wetlandscape and on the availability and accessibility of associated local data. This novel database (available through PANGAEA https://doi.org/10.1594/PANGAEA.907398; Ghajarnia et al., 2019) can support site assessments; cross-regional comparisons; and scenario analyses of the roles and impacts of land use, hydroclimatic and wetland conditions, and changes in whole-wetlandscape functions and ecosystem services

    Pathways from research to sustainable development: insights from ten research projects in sustainability and resilience

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    Drawing on collective experience from ten collaborative research projects focused on the Global South, we identify three major challenges that impede the translation of research on sustainability and resilience into better-informed choices by individuals and policy-makers that in turn can support transformation to a sustainable future. The three challenges comprise: (i) converting knowledge produced during research projects into successful knowledge application; (ii) scaling up knowledge in time when research projects are short-term and potential impacts are long-term; and (iii) scaling up knowledge across space, from local research sites to larger-scale or even global impact. Some potential pathways for funding agencies to overcome these challenges include providing targeted prolonged funding for dissemination and outreach, and facilitating collaboration and coordination across different sites, research teams, and partner organizations. By systematically documenting these challenges, we hope to pave the way for further innovations in the research cycle

    Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

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    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

    Imagining an Imperial Modernity: Universities and the West African Roots of Colonial Development

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    © 2016 Informa UK Limited, trading as Taylor & Francis GroupThis article takes the formation and work of the ‘Elliot’ Commission on Higher Education in West Africa (1943–45) to reconsider the roots of British colonial development. Late colonial universities were major development projects, although they have rarely been considered as such. Focusing particularly on the Nigerian experience and the controversy over Yaba Higher College (founded 1934), the article contends that late colonial plans for universities were not produced in Britain and then exported to West African colonies. Rather, they were formed through interactions between agendas and ideas with roots in West Africa, Britain and elsewhere. These debates exhibited asymmetries of power but produced some consensus about university development. African and British actors conceptualised modern education by combining their local concerns with a variety of supra-local geographical frames for development, which included the British Empire and the individual colony. The British Empire did not in this case forestall development, but shaped the ways in which development was conceived

    Sustainable agriculture : From global challenges to local land management

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    Despite the success of agriculture management practices in increasing the availability of food needed to meet the requirements of the expanding global population, there are increasing demands placed on the resources on which the sector depends. Opportunities for the development of agricultural systems are constrained by increasing competition, from other sectors, for shared resources. In tackling this constraint, agricultural management solutions are often narrowly focused on problems related to single resources. But this single focus may lead to unintended trade-offs. To make sound management decisions, there is a need to better understand trade-offs which may occur from resource use efficiency solutions implemented in the agricultural sector. With a particular focus on soil and water resources, the aim of this thesis was to investigate trade-offs that occur, when meeting demands placed on agriculture systems, if management solutions are narrowly focused. Broadly, we hypothesize that approaches to land management that take a more holistic view of agricultural systems being part of an ecosystem mosaic should be adopted to ensure sustainability. A global assessment of potential land requirements shows that national level production of sufficiently nutritious food may be constrained by land availability, such that allocation of land to nutritious crop production might come at the cost of lost land for other crops or uses. This constraint will be the most prevalent in African states. In further studies, we focused on the management of water resources, which are becoming particularly limiting for crops that have high water demands, such as rice. Through a meta-analysis of paired plot experiments, which assessed the effect of water saving irrigation in rice production, and soil sampling within An Giang, a major rice producing province of Vietnam, we examined the effect of water management practices on soil properties. The meta-analysis finds that significant reductions in soil organic carbon, and potentially organic matter bound nutrients, have been observed when water efficient practices replace continual flood irrigation. This suggests that, although yield reductions may not be seen in the short term, water saving irrigation may, over time, lead to reductions in soil fertility and yields. Within An Giang province, there are concerns regarding the loss of flood-borne, nutrient rich, sediments in fields where the annual flood waters have been completely regulated. However, we find that this complete regulation does not result in reduced soil nutrient properties when compared to areas where floods are only partially regulated. The effect of different land management practices on soil properties were further explored within the Kilombero Valley, Tanzania. Comparing farming practices along a gradient of intensity, we found contrasting effects of irrigation and fertilization, with irrigation increasing soil organic carbon and fertilization reducing soil organic carbon. Overall, the results of this thesis highlight the importance of looking beyond meeting short term needs, which can have negative long term consequences. The success of land management practices implemented now do not, necessarily, equate to their continued success in the future. As demands placed on agriculture are going to increase, the long term trade-offs which may occur from present practices must be at the forefront of agricultural management

    Sustainable agriculture : From global challenges to local land management

    No full text
    Despite the success of agriculture management practices in increasing the availability of food needed to meet the requirements of the expanding global population, there are increasing demands placed on the resources on which the sector depends. Opportunities for the development of agricultural systems are constrained by increasing competition, from other sectors, for shared resources. In tackling this constraint, agricultural management solutions are often narrowly focused on problems related to single resources. But this single focus may lead to unintended trade-offs. To make sound management decisions, there is a need to better understand trade-offs which may occur from resource use efficiency solutions implemented in the agricultural sector. With a particular focus on soil and water resources, the aim of this thesis was to investigate trade-offs that occur, when meeting demands placed on agriculture systems, if management solutions are narrowly focused. Broadly, we hypothesize that approaches to land management that take a more holistic view of agricultural systems being part of an ecosystem mosaic should be adopted to ensure sustainability. A global assessment of potential land requirements shows that national level production of sufficiently nutritious food may be constrained by land availability, such that allocation of land to nutritious crop production might come at the cost of lost land for other crops or uses. This constraint will be the most prevalent in African states. In further studies, we focused on the management of water resources, which are becoming particularly limiting for crops that have high water demands, such as rice. Through a meta-analysis of paired plot experiments, which assessed the effect of water saving irrigation in rice production, and soil sampling within An Giang, a major rice producing province of Vietnam, we examined the effect of water management practices on soil properties. The meta-analysis finds that significant reductions in soil organic carbon, and potentially organic matter bound nutrients, have been observed when water efficient practices replace continual flood irrigation. This suggests that, although yield reductions may not be seen in the short term, water saving irrigation may, over time, lead to reductions in soil fertility and yields. Within An Giang province, there are concerns regarding the loss of flood-borne, nutrient rich, sediments in fields where the annual flood waters have been completely regulated. However, we find that this complete regulation does not result in reduced soil nutrient properties when compared to areas where floods are only partially regulated. The effect of different land management practices on soil properties were further explored within the Kilombero Valley, Tanzania. Comparing farming practices along a gradient of intensity, we found contrasting effects of irrigation and fertilization, with irrigation increasing soil organic carbon and fertilization reducing soil organic carbon. Overall, the results of this thesis highlight the importance of looking beyond meeting short term needs, which can have negative long term consequences. The success of land management practices implemented now do not, necessarily, equate to their continued success in the future. As demands placed on agriculture are going to increase, the long term trade-offs which may occur from present practices must be at the forefront of agricultural management

    Text mining of cancer-related information: Review of current status and future directions

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    AbstractPurposeThis paper reviews the research literature on text mining (TM) with the aim to find out (1) which cancer domains have been the subject of TM efforts, (2) which knowledge resources can support TM of cancer-related information and (3) to what extent systems that rely on knowledge and computational methods can convert text data into useful clinical information. These questions were used to determine the current state of the art in this particular strand of TM and suggest future directions in TM development to support cancer research.MethodsA review of the research on TM of cancer-related information was carried out. A literature search was conducted on the Medline database as well as IEEE Xplore and ACM digital libraries to address the interdisciplinary nature of such research. The search results were supplemented with the literature identified through Google Scholar.ResultsA range of studies have proven the feasibility of TM for extracting structured information from clinical narratives such as those found in pathology or radiology reports. In this article, we provide a critical overview of the current state of the art for TM related to cancer. The review highlighted a strong bias towards symbolic methods, e.g. named entity recognition (NER) based on dictionary lookup and information extraction (IE) relying on pattern matching. The F-measure of NER ranges between 80% and 90%, while that of IE for simple tasks is in the high 90s. To further improve the performance, TM approaches need to deal effectively with idiosyncrasies of the clinical sublanguage such as non-standard abbreviations as well as a high degree of spelling and grammatical errors. This requires a shift from rule-based methods to machine learning following the success of similar trends in biological applications of TM. Machine learning approaches require large training datasets, but clinical narratives are not readily available for TM research due to privacy and confidentiality concerns. This issue remains the main bottleneck for progress in this area. In addition, there is a need for a comprehensive cancer ontology that would enable semantic representation of textual information found in narrative reports

    Global assessment of accountability in water and sanitation services using GLAAS data

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    The Global Analysis and Assessment of Sanitation and Drinking-Water (GLAAS) is one of UN-Water’s regular reports. Its focuses include aspects of investment and the enabling environment for the delivery of water, sanitation and hygiene services. Accountability refers to the mechanisms through which duty bearers, elected officials and service providers report to rights holders and other stakeholders within the service delivery framework. Accountability contributes to good sector performance and the overall sustainability of services. The aim of this study was to evaluate the level of accountability in the drinking-water and sanitation sector globally, based on the available data from the GLAAS survey of 2014. To achieve this, accountability was defined from a human rights perspective, and particularised for water and sanitation. Next the quantitative and open-ended questions from the GLAAS survey that related to this definition were analysed for all 94 responding countries. Comparisons were drawn between water and sanitation services in urban and rural settings, and regional trends were identified. The results show higher levels of accountability for water than sanitation services, and limited information on wastewater. Potential means to strengthen accountability in water and sanitation globally are seen to include improving access to information on the services provided, enacting participation policies and increasing the capacity of regulatory institutions. Particular attention should be paid to rural services. The GLAAS survey could be modified for a better understanding of the accountability mechanisms for WASH service provision
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