A syllable-based investigation of coarticulation

Coarticulation has been long investigated in Speech Sciences and Linguistics (Kühnert & Nolan, 1999). This thesis explores coarticulation through a syllable based model (Y. Xu, 2020). First, it is hypothesised that consonant and vowel are synchronised at the syllable onset for the sake of reducing temporal degrees of freedom, and such synchronisation is the essence of coarticulation. Previous efforts in the examination of CV alignment mainly report onset asynchrony (Gao, 2009; Shaw & Chen, 2019). The first study of this thesis tested the synchrony hypothesis using articulatory and acoustic data in Mandarin. Departing from conventional approaches, a minimal triplet paradigm was applied, in which the CV onsets were determined through the consonant and vowel minimal pairs, respectively. Both articulatory and acoustical results showed that CV articulation started in close temporal proximity, supporting the synchrony hypothesis. The second study extended the research to English and syllables with cluster onsets. By using acoustic data in conjunction with Deep Learning, supporting evidence was found for co-onset, which is in contrast to the widely reported c-center effect (Byrd, 1995). Secondly, the thesis investigated the mechanism that can maximise synchrony – Dimension Specific Sequential Target Approximation (DSSTA), which is highly relevant to what is commonly known as coarticulation resistance (Recasens & Espinosa, 2009). Evidence from the first two studies show that, when conflicts arise due to articulation requirements between CV, the CV gestures can be fulfilled by the same articulator on separate dimensions simultaneously. Last but not least, the final study tested the hypothesis that resyllabification is the result of coarticulation asymmetry between onset and coda consonants. It was found that neural network based models could infer syllable affiliation of consonants, and those inferred resyllabified codas had similar coarticulatory structure with canonical onset consonants. In conclusion, this thesis found that many coarticulation related phenomena, including local vowel to vowel anticipatory coarticulation, coarticulation resistance, and resyllabification, stem from the articulatory mechanism of the syllable

Deep learning assessment of syllable affiliation of intervocalic consonants

In English, a sentence like “He made out our intentions.” could be misperceived as “He may doubt our intentions.” because the coda /d/ sounds like it has become the onset of the next syllable. The nature and occurrence condition of this resyllabification phenomenon are unclear, however. Previous empirical studies mainly relied on listener judgment, limited acoustic evidence, such as voice onset time, or average formant values to determine the occurrence of resyllabification. This study tested the hypothesis that resyllabification is a coarticulatory reorganisation that realigns the coda consonant with the vowel of the next syllable. Deep learning in conjunction with dynamic time warping (DTW) was used to assess syllable affiliation of intervocalic consonants. The results suggest that convolutional neural network- and recurrent neural network-based models can detect cases of resyllabification using Mel-frequency spectrograms. DTW analysis shows that neural network inferred resyllabified sequences are acoustically more similar to their onset counterparts than their canonical productions. A binary classifier further suggests that, similar to the genuine onsets, the inferred resyllabified coda consonants are coarticulated with the following vowel. These results are interpreted with an account of resyllabification as a speech-rate-dependent coarticulatory reorganisation mechanism in speech

Accurate Multi-physics Numerical Analysis of Particle Preconcentration Based on Ion Concentration Polarization

This paper studies mechanism of preconcentration of charged particles in a straight micro-channel embedded with permselective membranes, by numerically solving coupled transport equations of ions, charged particles and solvent fluid without any simplifying assumptions. It is demonstrated that trapping and preconcentration of charged particles are determined by the interplay between drag force from the electroosmotic fluid flow and the electrophoretic force applied trough the electric field. Several insightful characteristics are revealed, including the diverse dynamics of co-ions and counter ions, replacement of co-ions by focused particles, lowered ion concentrations in particle enriched zone, and enhanced electroosmotic pumping effect etc. Conditions for particles that may be concentrated are identified in terms of charges, sizes and electrophoretic mobilities of particles and co-ions. Dependences of enrichment factor on cross-membrane voltage, initial particle concentration and buffer ion concentrations are analyzed and the underlying reasons are elaborated. Finally, post priori a condition for validity of decoupled simulation model is given based on charges carried by focused charge particles and that by buffer co-ions. These results provide important guidance in the design and optimization of nanofluidic preconcentration and other related devices.Comment: 18 pages, 11 firgure

Superhydrophobic and Oleophobic Surfaces. Synthesis and Applications

Surface patterning is an overwhelming approach to mechanically modifying metal surfaces and improving their tribological properties, such as repellency, lower friction, and more excellent corrosion resistance. Patterned surfaces can be applied to various industrial uses, such as cutting tools, submarines, and self-cleaning surfaces. In this paper, the novel nature-inspired flat-top-pillar double-undercut designs were proposed to achieve an apparent angle that satisfies super-hydrophobicity and endure higher pressure on which external forces are exerted. The main objective is to enlarge the change in Gibbs free energy for the system to exhibit a heterogeneous wetting to a homogeneous one by excavation on the surface needed to be patterned to obtain an additional 30% of the atmospheric pressure while maintaining an apparent contact angle of greater than 150°. The analytical approach yielded decent results showing an extra pressure of more than 3 atm averaged from three different scales of two distinct double-undercut designs calculated by the stability equation derived by the Gibbs free energy. Numerical, finite element analysis was also performed in COMSOL-Multiphysics and demonstrated a Canthotaxis wetting transition phenomenon. An average of 800 pascals of additional pressure was achieved for designs of three distinct permutations of double-undercut angles (50°-40°, 50°-36°, and 40°-36°). Specimens were fabricated on silicon wafers by PolyMUMPs method for proof-of-concept and were ready for the future experiment on apparent contact angle and cross-sectional SEM at post breaching the Cassie-Baxter state

Deconvolution approach for floating wind turbines

Green renewable energy is produced by floating offshore wind turbines (FOWT), a crucial component of the modern offshore wind energy industry. It is a safety concern to accurately evaluate excessive weights while the FOWT operates in adverse weather conditions. Under certain water conditions, dangerous structural bending moments may result in operational concerns. Using commercial FAST software, the study's hydrodynamic ambient wave loads were calculated and converted into FOWT structural loads. This article suggests a Monte Carlo-based engineering technique that, depending on simulations or observations, is computationally effective for predicting extreme statistics of either the load or the response process. The innovative deconvolution technique has been thoroughly explained. The suggested approach effectively uses the entire set of data to produce a clear but accurate estimate for severe response values and fatigue life. In this study, estimated extreme values obtained using a novel deconvolution approach were compared to identical values produced using the modified Weibull technique. It is expected that the enhanced new de-convolution methodology may offer a dependable and correct forecast of severe structural loads based on the overall performance of the advised de-convolution approach due to environmental wave loading.publishedVersio

A Label-Free Platform for Identification of Exosomes from Different Sources.

Exosomes contain cell- and cell-state-specific cargos of proteins, lipids, and nucleic acids and play significant roles in cell signaling and cell-cell communication. Current research into exosome-based biomarkers has relied largely on analyzing candidate biomarkers, i.e., specific proteins or nucleic acids. However, this approach may miss important biomarkers that are yet to be identified. Alternative approaches are to analyze the entire exosome system, either by "omics" methods or by techniques that provide "fingerprints" of the system without identifying each individual biomolecule component. Here, we describe a platform of the latter type, which is based on surface-enhanced Raman spectroscopy (SERS) in combination with multivariate analysis, and demonstrate the utility of this platform for analyzing exosomes derived from different biological sources. First, we examined whether this analysis could use exosomes isolated from fetal bovine serum using a simple, commercially available isolation kit or necessitates the higher purity achieved by the "gold standard" ultracentrifugation/filtration procedure. Our data demonstrate that the latter method is required for this type of analysis. Having established this requirement, we rigorously analyzed the Raman spectral signature of individual exosomes using a unique, hybrid SERS substrate made of a graphene-covered Au surface containing a quasi-periodic array of pyramids. To examine the source of the Raman signal, we used Raman mapping of low and high spatial resolution combined with morphological identification of exosomes by scanning electron microscopy. Both approaches suggested that the spectra were collected from single exosomes. Finally, we demonstrate for the first time that our platform can distinguish among exosomes from different biological sources based on their Raman signature, a promising approach for developing exosome-based fingerprinting. Our study serves as a solid technological foundation for future exploration of the roles of exosomes in various biological processes and their use as biomarkers for disease diagnosis and treatment monitoring

Optimal map-making with singularities

In this work, we investigate the optimal map-making technique for the linear system $\bm{d}=\bm{A}\bm{x}+\bm{n}$ while carefully taking into account singularities that may come from either the covariance matrix $\bm{C} = \$ or the main matrix$\bm{A}$. We first describe the general optimal solution, which is quite complex, and then use the modified pseudo inverse to create a near-optimal solution, which is simple, robust, and can significantly alleviate the unwanted noise amplification during map-making. The effectiveness of the nearly optimal solution is then compared to that of the naive co-adding solution and the standard pseudo inverse solution, showing noticeable improvements. Interestingly, all one needs to get the near-optimal solution with singularity is just a tiny change to the traditional optimal solution that is designed for the case without singularity.Comment: 24 pages, 7 figures, and 2 appendice

Simulation of the Signal Propagation for Thin-gap RPC in the ATLAS Phase-II Upgrade

Thin-gap Resistive Plate Chambers (RPCs) with a 1 mm gap size are introduced in the Phase-II ATLAS upgrade. Smaller avalanche charge due to the reduced gap size raises concerns for signal integrity. This work focuses on the RPC signal propagation process in lossless conditions, and an analytical study is implemented for the ATLAS RPC. Detector modeling is presented, and the simulation of the RPC signal is discussed in detail. Simulated characteristic impedance and crosstalk have been compared with the measured value to validate this model. This method is applied to different RPC design geometries, including the newly proposed $\eta-\eta$ readout scheme.Comment: 6 pages, 5 figures, submitted to NIM