SL(2,Z) tensionless string backgrounds in IIB string theory

We examine a tensionless limit of a SL(2,Z) set of background solutions to IIB supergravity theory, obtained by performing an infinite boost. This yields a solution that corresponds to taking the original string tension to zero. The limit reproduces ordinary Minkowski space except for a delta-like singularity along the string. We study the field content and the energy momentum tensor.Comment: 1+8 pages, LaTeX, JHEP styl

Transition density of diffusion on Sierpinski gasket and extension of Flory's formula

Some problems related to the transition density u(t,x) of the diffusion on the Sierpinski gasket are considerd, based on recent rigorous results and detailed numerical calculations. The main contents are an extension of Flory's formula for the end-to-end distance exponent of self-avoiding walks on the fractal spaces, and an evidence of the oscillatory behavior of u(t,x) on the Sierpinski gasket.Comment: 11 pages, REVTEX, 2 postscript figure

Evaluating Short-Run Forecasting Properties of the KOF Employment Indicator for Switzerland in Real Time

This study investigates the usefulness of the business tendency surveys collected at the KOF institute for short-term forecasting of employment in Switzerland aggregated in the KOF Employment Indicator. We use the real time dataset in order to simulate the actual predictive process using only the information that was available at the time when predictions were made. We evaluate the presence of predictive content of the KOF Employment Indicator both for nowcasts that are published two months before the first official release and for one-quarter ahead forecasts published five months before the first official release. We find that inclusion of the KOF Employment Indicator leads to substantial improvement both in in-sample as well as, more importantly, in out-of-sample prediction accuracy. This conclusion holds both for nowcasts and one-quarter ahead forecasts

Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes

Essentials Deep vein thrombosis (DVT) has a large unknown genetic component. We sequenced coding areas of 734 hemostasis-related genes in 899 DVT patients and 599 controls. Variants in F5, FGA-FGG, CYP4V2-KLKB1-F11, and ABO were associated with DVT risk. Associations in KLKB1 and F5 suggest a more complex genetic architecture than previously thought. Summary: Background Although several genetic risk factors for deep vein thrombosis (DVT) are known, almost all related to hemostasis, a large genetic component remains unexplained. Objectives To identify novel genetic determinants by using targeted DNA sequencing. Patients/Methods We included 899 DVT patients and 599 controls from three case\u2013control studies (DVT-Milan, Multiple Environmental and Genetic Assessment of risk factors for venous thrombosis [MEGA], and the Thrombophilia, Hypercoagulability and Environmental Risks in Venous Thromboembolism [THE-VTE] study) for sequencing of the coding regions of 734 genes involved in hemostasis or related pathways. We performed single-variant association tests for common variants (minor allele frequency [MAF] 65 1%) and gene-based tests for rare variants (MAF 64 1%), accounting for multiple testing by use of the false discovery rate (FDR). Results Sixty-two of 3617 common variants were associated with DVT risk (FDR 0.2). Conclusions We confirmed associations between DVT and common variants in F5,ABO,FGA\u2013FGG, and CYP4V2\u2013KLKB1\u2013F11, and observed secondary signals in F5 and CYP4V2\u2013KLKB1\u2013F11 that warrant replication and fine-mapping in larger studies