6,311 research outputs found
Inhomogeneous Nucleation of Quark-Gluon Plasma in High Energy Nuclear Collisions
We estimate the probability that a hard nucleon-nucleon collision is able to
nucleate a seed of quark--gluon plasma in the surrounding hot and dense
hadronic matter formed during a central collision of two large nuclei at AGS
energies. The probability of producing at least one such seed is on the order
of 1-100\%. We investigate the influence of quark--gluon plasma formation on
the observed multiplicity distribution and find that it may lead to noticable
structure in the form of a bump or shoulder.Comment: 16 pages, latex and 12 ps figures available on reques
Helioseismic Holography of an Artificial Submerged Sound Speed Perturbation and Implications for the Detection of Pre-Emergence Signatures of Active Regions
We use a publicly available numerical wave-propagation simulation of Hartlep
et al. 2011 to test the ability of helioseismic holography to detect signatures
of a compact, fully submerged, 5% sound-speed perturbation placed at a depth of
50 Mm within a solar model. We find that helioseismic holography as employed in
a nominal "lateral-vantage" or "deep-focus" geometry employing quadrants of an
annular pupil is capable of detecting and characterizing the perturbation. A
number of tests of the methodology, including the use of a plane-parallel
approximation, the definition of travel-time shifts, the use of different
phase-speed filters, and changes to the pupils, are also performed. It is found
that travel-time shifts made using Gabor-wavelet fitting are essentially
identical to those derived from the phase of the Fourier transform of the
cross-covariance functions. The errors in travel-time shifts caused by the
plane-parallel approximation can be minimized to less than a second for the
depths and fields of view considered here. Based on the measured strength of
the mean travel-time signal of the perturbation, no substantial improvement in
sensitivity is produced by varying the analysis procedure from the nominal
methodology in conformance with expectations. The measured travel-time shifts
are essentially unchanged by varying the profile of the phase-speed filter or
omitting the filter entirely. The method remains maximally sensitive when
applied with pupils that are wide quadrants, as opposed to narrower quadrants
or with pupils composed of smaller arcs. We discuss the significance of these
results for the recent controversy regarding suspected pre-emergence signatures
of active regions
Comparing various multi-component global heliosphere models
Modeling of the global heliosphere seeks to investigate the interaction of
the solar wind with the partially ionized local interstellar medium. Models
that treat neutral hydrogen self-consistently and in great detail, together
with the plasma, but that neglect magnetic fields, constitute a sub-category
within global heliospheric models. There are several different modeling
strategies used for this sub-category in the literature. Differences and
commonalities in the modeling results from different strategies are pointed
out. Plasma-only models and fully self-consistent models from four research
groups, for which the neutral species is modeled with either one, three, or
four fluids, or else kinetically, are run with the same boundary parameters and
equations. They are compared to each other with respect to the locations of key
heliospheric boundary locations and with respect to the neutral hydrogen
content throughout the heliosphere. In many respects, the models' predictions
are similar. In particular, the locations of the termination shock agree to
within 7% in the nose direction and to within 14% in the downwind direction.
The nose locations of the heliopause agree to within 5%. The filtration of
neutral hydrogen from the interstellar medium into the inner heliosphere,
however, is model dependent, as are other neutral results including the
hydrogen wall. These differences are closely linked to the strength of the
interstellar bow shock. The comparison also underlines that it is critical to
include neutral hydrogen into global heliospheric models.Comment: 10 pages, 4 figures, submitted to a special section at A&A of an ISSI
team "Determination of the physical Hydrogen parameters of the LIC from
within the Heliosphere
Time--Distance Helioseismology Data Analysis Pipeline for Helioseismic and Magnetic Imager onboard Solar Dynamics Observatory (SDO/HMI) and Its Initial Results
The Helioseismic and Magnetic Imager onboard the Solar Dynamics Observatory
(SDO/HMI) provides continuous full-disk observations of solar oscillations. We
develop a data-analysis pipeline based on the time-distance helioseismology
method to measure acoustic travel times using HMI Doppler-shift observations,
and infer solar interior properties by inverting these measurements. The
pipeline is used for routine production of near-real-time full-disk maps of
subsurface wave-speed perturbations and horizontal flow velocities for depths
ranging from 0 to 20 Mm, every eight hours. In addition, Carrington synoptic
maps for the subsurface properties are made from these full-disk maps. The
pipeline can also be used for selected target areas and time periods. We
explain details of the pipeline organization and procedures, including
processing of the HMI Doppler observations, measurements of the travel times,
inversions, and constructions of the full-disk and synoptic maps. Some initial
results from the pipeline, including full-disk flow maps, sunspot subsurface
flow fields, and the interior rotation and meridional flow speeds, are
presented.Comment: Accepted by Solar Physics topical issue 'Solar Dynamics Observatory
The Aspergillus nidulans cnxABC locus is a single gene encoding two catalytic domains required for synthesis of precursor Z, an intermediate in molybdenum cofactor biosynthesis
Seismic Emissions from a Highly Impulsive M6.7 Solar Flare
On 10 March 2001 the active region NOAA 9368 produced an unusually impulsive
solar flare in close proximity to the solar limb. This flare has previously
been studied in great detail, with observations classifying it as a type 1
white-light flare with a very hard spectrum in hard X-rays. The flare was also
associated with a type II radio burst and coronal mass ejection. The flare
emission characteristics appeared to closely correspond with previous instances
of seismic emission from acoustically active flares. Using standard local
helioseismic methods, we identified the seismic signatures produced by the
flare that, to date, is the least energetic (in soft X-rays) of the flares
known to have generated a detectable acoustic transient. Holographic analysis
of the flare shows a compact acoustic source strongly correlated with the
impulsive hard X-ray, visible continuum, and radio emission. Time-distance
diagrams of the seismic waves emanating from the flare region also show faint
signatures, mainly in the eastern sector of the active region. The strong
spatial coincidence between the seismic source and the impulsive visible
continuum emission reinforces the theory that a substantial component of the
seismic emission seen is a result of sudden heating of the low photosphere
associated with the observed visible continuum emission. Furthermore, the
low-altitude magnetic loop structure inferred from potential--field
extrapolations in the flaring region suggests that there is a significant
inverse correlation between the seismicity of a flare and the height of the
magnetic loops that conduct the particle beams from the corona.Comment: 16 pages, 7 figures, Solar Physics Topical Issue: SOHO 19/GONG 2007
"Seismology of Magnetic Activity", Accepte
Live Attenuated Varicella-Zoster Vaccine in Hematopoietic Stem Cell Transplantation Recipients
AbstractHematopoietic stem cell transplantation (HSCT) recipients are at risk for varicella-zoster virus (VZV) reactivation. Vaccination may help restore VZV immunity; however, the available live attenuated VZV vaccine (Zostavax) is contraindicated in immunocompromised hosts. We report our experience with using a single dose of VZV vaccine in 110 adult autologous and allogeneic HSCT recipients who were about 2Â years after transplantation, free of graft-versus-host disease, and not receiving immunosuppression. One hundred eight vaccine recipients (98.2%) had no clinically apparent adverse events with a median follow-up period of 9.5Â months (interquartile range, 6 to 16; range, 2 to 28). Two vaccine recipients (1.8%) developed a skin rash (one zoster-like rash with associated pain, one varicella-like) within 42Â days post-vaccination that resolved with antiviral therapy. We could not confirm if these rashes were due to vaccine (Oka) or wild-type VZV. No other possible cases of VZV reactivation have occurred with about 1178Â months of follow-up. Live attenuated zoster vaccine appears generally safe in this population when vaccinated as noted; the overall vaccination risk needs to be weighed against the risk of wild-type VZV disease in this high-risk population
Analysis of lesion localisation at colonoscopy: outcomes from a multi-centre U.K. study
Background:
Colonoscopy is currently the gold standard for detection of colorectal lesions, but may be limited in anatomically localising lesions. This audit aimed to determine the accuracy of colonoscopy lesion localisation, any subsequent changes in surgical management and any potentially influencing factors.
Methods:
Patients undergoing colonoscopy prior to elective curative surgery for colorectal lesion/s were included from 8 registered U.K. sites (2012–2014). Three sets of data were recorded: patient factors (age, sex, BMI, screener vs. symptomatic, previous abdominal surgery); colonoscopy factors (caecal intubation, scope guide used, colonoscopist accreditation) and imaging modality. Lesion localisation was standardised with intra-operative location taken as the gold standard. Changes to surgical management were recorded.
Results:
364 cases were included; majority of lesions were colonic, solitary, malignant and in symptomatic referrals. 82% patients had their lesion/s correctly located at colonoscopy. Pre-operative CT visualised lesion/s in only 73% of cases with a reduction in screening patients (64 vs. 77%; p = 0.008). 5.2% incorrectly located cases at colonoscopy underwent altered surgical management, including conversion to open. Univariate analysis found colonoscopy accreditation, scope guide use, incomplete colonoscopy and previous abdominal surgery significantly influenced lesion localisation. On multi-variate analysis, caecal intubation and scope guide use remained significant (HR 0.35, 0.20–0.60 95% CI and 0.47; 0.25–0.88, respectively).
Conclusion:
Lesion localisation at colonoscopy is incorrect in 18% of cases leading to potentially significant surgical management alterations. As part of accreditation, colonoscopists need lesion localisation training and awareness of when inaccuracies can occur
Surface-focused Seismic Holography of Sunspots: I. Observations
We present a comprehensive set of observations of the interaction of p-mode
oscillations with sunspots using surface-focused seismic holography. Maps of
travel-time shifts, relative to quiet-Sun travel times, are shown for incoming
and outgoing p modes as well as their mean and difference. We compare results
using phase-speed filters with results obtained with filters that isolate
single p-mode ridges, and further divide the data into multiple temporal
frequency bandpasses. The f mode is removed from the data. The variations of
the resulting travel-time shifts with magnetic-field strength and with the
filter parameters are explored. We find that spatial averages of these shifts
within sunspot umbrae, penumbrae, and surrounding plage often show strong
frequency variations at fixed phase speed. In addition, we find that positive
values of the mean and difference travel-time shifts appear exclusively in
waves observed with phase-speed filters that are dominated by power in the
low-frequency wing of the p1 ridge. We assess the ratio of incoming to outgoing
p-mode power using the ridge filters and compare surface-focused holography
measurements with the results of earlier published p-mode scattering
measurements using Fourier-Hankel decomposition.Comment: Solar Physics, accepte
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