218 research outputs found

    The Oral Health of a Group of 19th Century South Australian Settlers in Relation to Their General Health and Compared with That of Contemporaneous Samples

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    The aims of this study are to determine the oral health status of a rare sample of 19th-century migrant settlers to South Australia, how oral conditions may have influenced their general health, and how the oral health of this group compares with contemporaneous samples in Australia, New Zealand, and Britain. Dentitions of 18 adults and 22 subadults were investigated using non-destructive methods (micro-CT, macroscopic, radiographic). Extensive carious lesions were identified in seventeen adults and four subadults, and from this group one subadult and sixteen adults had antemortem tooth loss. Sixteen adults showed evidence of periodontal disease. Enamel hypoplastic (EH) defects were identified in fourteen adults and nine subadults. Many individuals with dental defects also had skeletal signs of comorbidities. South Australian individuals had the same percentage of carious lesions as the British sample (53%), more than other historic Australian samples, but less than a contemporary New Zealand sample. Over 50% of individuals from all the historic cemeteries had EH defects, suggesting systemic health insults during dental development were common during the 19th century. The overall oral health of the South Australian settlers was poor but, in some categories, (tooth wear, periapical abscess, periodontal disease), better than the other historic samples

    What drives support for higher public spending?

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    This paper examines the role of individual and household characteristics in explaining patterns of support for higher public spending on seven of the most important public spending programmes including health, education, the police and defence. Different groups in the population, such as the elderly, those who are highly educated, and those who support particular political parties, tend to support distinctive types of spending. There is some evidence that use of private alternatives to public services reduces support for higher state spending in the fields of health care and transport, although no evidence is found that this is true for education. There is a fair degree of consonance between the factors affecting support for higher spending which individuals perceive as being in their own interest and that which they support as being in the interests of the country as a whole. Those differences that are found appear readily explicable. The association between having children in the household and supporting higher spending on education, for instance, is far stronger in the case of private interests than for the country as a whole. Personal use of private sector alternatives also appears to have less impact on perceptions of the national interest in expanded public provision than on perceptions of self interest. There is some evidence that individuals tend to express a greater degree of support for those benefits for which they might or do qualify themselves. Some groups, such as better-off households and Conservative supporters, are clearly more hostile than others to spending on social security spending generally.

    Draft genome sequence of Raoultella ornithinolytica P079F W, isolated from the feces of a preterm infant

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    Here, we describe the draft genome sequence of Raoultella ornithinolytica P079F W, isolated from the feces of an infant residing in a neonatal intensive care unit during an ongoing study to characterize the neonate gut microbiota. P079F W will be used in studies investigating the role of the microbiome in neonatal infections

    Summer crops: relative water use efficiencies and legacy impacts in farming systems

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    Take home message • While summer crops offer rotational options in the farming system, choose the correct crop to match your available soil water and crop history • Sorghum is a reliable performer often exceeding other options in terms of returnedpermmusedCottonandmaizerequirehigherwateravailabilityandproducelessreliableWUE( returned per mm used • Cotton and maize require higher water availability and produce less reliable WUE (/mm). However, cotton has legacy impacts on water availability for subsequent crops that should be considered • Mungbean can produce higher /mminlowwateravailabilitysituations(150mmofplantavailablewaterwillmaximisecropWUEandprofitability.Everyextrammatsowingcouldbeworthasmuchas/mm in low water availability situations ( 150 mm of plant available water will maximise crop WUE and profitability. Every extra mm at sowing could be worth as much as 35-70 extra return/ha • Higher density sorghum crops may provide greater crop competition against weeds and potential upside yield benefits in good season. We have seen limited legacy benefits (e.g. improved ground cover) or costs (e.g. greater soil water/nutrient extraction) for soil water or nutrient availability

    Managing crop differences in soil water extraction and legacy impacts within a farming system

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    Take home message Shorter season, faster maturing crops can leave residual surface water from unutilised late season rain and/or residual deep water due to shallower roots and quicker maturity Legumes such as lentils, fababeans, field pea, and chickpea often leave 20-40 mm extra residual soil water compared to canola and winter cereals Higher residual water may not remain at sowing of next crop – fallow efficiency differences between crops and seasons can influence this – e.g. low cover after legumes For summer crops, mungbean typically leaves 20mm more residual water than sorghum/maize while cotton leaves 20mm less (i.e. mungbean > sorghum/maize > cotton) Early-sown, slower maturing crops (e.g. early sown winter crops) can dry the profile deeper (>2m) and utilise deep stored soil to support higher yield in dry springs. The legacy of drier soil may warrant changes to crop sequence and management to avoid yield penalties Extra residual water at sowing can increase grain yield of subsequent crops when water is limited during the critical period for yield determination so the marginal WUE (i.e. extra yield per mm of extra soil water available) can be very high (>60kg/ha/mm) As the value of the residual water is seasonally dependent, understanding how management (crop choice, sowing dates, N management) can be adjusted to capture value from such legacies across a sequence of crops is the goal of current farming systems research

    Continuous Brain-derived Neurotrophic Factor (BDNF) Infusion After Methylprednisolone Treatment in Severe Spinal Cord Injury

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    Although methylprednisolone (MP) is the standard of care in acute spinal cord injury (SCI), its functional outcome varies in clinical situation. Recent report demonstrated that MP depresses the expression of growth-promoting neurotrophic factors after acute SCI. The present study was designed to investigate whether continuous infusion of brain-derived neurotrophic factor (BDNF) after MP treatment promotes functional recovery in severe SCI. Contusion injury was produced at the T10 vertebral level of the spinal cord in adult rats. The rats received MP intravenously immediately after the injury and BDNF was infused intrathecally using an osmotic mini-pump for six weeks. Immunohistochemical methods were used to detect ED-1, Growth associated protein-43 (GAP-43), neurofilament (NF), and choline acethyl transferase (ChAT) levels. BDNF did not alter the effect of MP on hematogenous inflammatory cellular infiltration. MP treatment with BDNF infusion resulted in greater axonal survival and regeneration compared to MP treatment alone, as indicated by increases in NF and GAP-43 gene expression. Adjunctive BDNF infusion resulted in better locomotor test scores using the Basso-Beattie-Bresnahan (BBB) test. This study demonstrated that continuous infusion of BDNF after initial MP treatment improved functional recovery after severe spinal cord injury without dampening the acute effect of MP

    City Know-How

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    Human health and planetary health are influenced by city lifestyles, city leadership, and city development. For both, worrying trends are leading to increasing concern and it is imperative that human health and environmental impacts become core foci in urban policy. Changing trajectory will require concerted action; the journal Cities & Health is dedicated to supporting the flow of knowledge, in all directions, to help make this happen. We wish to foster communication between researchers, practitioners, policy-makers, communities, and decision-makers in cities. This is the purpose of the City Know-how section of the journal. ‘Research for city practice’ disseminates lessons from research by explaining key messages for city leaders, communities, and the professions involved in city policy and practice. ‘City shorts’ provide glimpses of what is being attempted or achieved ‘on the ground’ and ’case studies’ are where you will find evaluations of interventions. Last, ‘Commentary and debate’ extends conversations we are having to develop and mobilize much needed new thinking. Join in these conversations. In order to strengthen the community of interest, we would like to include many and varied voices, including those from younger practitioners and researchers who are supporting health and health equity in everyday urban lives

    Development of a longitudinal integrated clerkship at an academic medical center

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    In 2005, medical educators at the University of California, San Francisco (UCSF), began developing the Parnassus Integrated Student Clinical Experiences (PISCES) program, a year-long longitudinal integrated clerkship at its academic medical center. The principles guiding this new clerkship were continuity with faculty preceptors, patients, and peers; a developmentally progressive curriculum with an emphasis on interdisciplinary teaching; and exposure to undiagnosed illness in acute and chronic care settings. Innovative elements included quarterly student evaluation sessions with all preceptors together, peer-to-peer evaluation, and oversight advising with an assigned faculty member. PISCES launched with eight medical students for the 2007/2008 academic year and expanded to 15 students for 2008/2009. Compared to UCSF's traditional core clerkships, evaluations from PISCES indicated significantly higher student satisfaction with faculty teaching, formal didactics, direct observation of clinical skills, and feedback. Student performance on discipline-specific examinations and United States Medical Licensing Examination step 2 CK was equivalent to and on standardized patient examinations was slightly superior to that of traditional peers. Participants' career interests ranged from primary care to surgical subspecialties. These results demonstrate that a longitudinal integrated clerkship can be implemented successfully at a tertiary care academic medical center

    Orthodontic treatment needs in the western region of Saudi Arabia: a research report

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    BACKGROUND: Evaluation of self perceived and actual need for orthodontic treatment helps in planning orthodontic services and estimating the required resources and man power. In the present study, the perceptive need as evaluated by patients and the actual need to orthodontic treatment, as assessed by orthodontists, were evaluated at two types of dental practices in the city of Jeddah using the Index of Orthodontic Treatment Need (IOTN). METHODS: A consecutive sample of 743 adults seeking orthodontic treatment at two different types of dental practices in Jeddah; King Abdulaziz University, Faculty of Dentistry (KAAU) (Free treatment) and two private dental polyclinics (PDP) (Paid treatment), was examined for orthodontic treatment need using the dental health component (DHC) of the IOTN. The self-perceived need for orthodontic treatment was also determined using the aesthetic component (AC) of the IOTN. The IOTN score and the incidence of each variable were calculated statistically. AC and DHC categories were compared using the Chi-Square and a correlation between them was assessed using Spearman's correlation test. AC and DHC were also compared between the two types of dental practices using the Chi-Square. RESULTS: The results revealed that among the 743 patients studied, 60.6% expressed no or slight need for treatment, 23.3% expressed moderate to borderline need and only16.1% thought they needed orthodontic treatment. Comparing these estimates to professional judgments, only 15.2% conformed to little or no need for treatment, 13.2% were assessed as in borderline need and 71.6% were assessed as in need for treatment (p < 0.001). Spearman's correlation test proved no correlation (r = -.045) between the two components. Comparing the AC and the DHC between the KAAU group and PDP group showed significant differences between the two groups (p < 0.001). CONCLUSION: Patient's perception to orthodontic treatment does not always correlate with professional assessment. The IOTN is a valid screening tool that should be used in orthodontic clinics for better services especially, in health centers that provide free treatment
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