716 research outputs found

    Procedures for management control of computer programming in Apollo

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    Procedures for management control of computer programming in Apollo projec

    Darwin-Lagrangian Analysis for the Interaction of a Point Charge and a Magnet: Considerations Related to the Controversy Regarding the Aharonov-Bohm and Aharonov-Casher Phase Shifts

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    The classical electromagnetic interaction of a point charge and a magnet is discussed by first calculating the interaction of point charge with a simple model magnetic moment and then suggesting a multiparticle limit. The Darwin Lagrangian is used to analyze the electromagnetic behavior of the model magnetic moment (composed of two oppositely charged particles of different mass in an initially circular orbit) interacting with a passing point charge. The changing mangetic moment is found to put a force back on a passing charge; this force is of order 1/c^2 and depends upon the magnitude of the magnetic moment. It is suggested that in the limit of a multiparticle magnetic toroid, the electric fields of the passing charge are screened out of the body of the magnet while the magnetic fields penetrate into the magnet. This is consistent with our understanding of the penetration of electromagnetic velocity fields into ohmic conductors. Conservation laws are discussed. The work corresponds to a classical electromagnetic analysis of the interaction which is basic to understanding the controversy over the Aharonov-Bohm and Aharonov-Casher phase shifts and represents a refutation of the suggestions of Aharonov, Pearle, and Vaidman.Comment: 33 page

    MACS: Multi-agent COTR system for Defense Contracting

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    The field of intelligent multi-agent systems has expanded rapidly in the recent past. Multi-agent architectures and systems are being investigated and continue to develop. To date, little has been accomplished in applying multi-agent systems to the defense acquisition domain. This paper describes the design, development, and related considerations of a multi-agent system in the area of procurement and contracting for the defense acquisition community

    Weighted-density approximation for general nonuniform fluid mixtures

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    In order to construct a general density-functional theory for nonuniform fluid mixtures, we propose an extension to multicomponent systems of the weighted-density approximation (WDA) of Curtin and Ashcroft [Phys. Rev. A 32, 2909 (1985)]. This extension corrects a deficiency in a similar extension proposed earlier by Denton and Ashcroft [Phys. Rev. A 42, 7312 (1990)], in that that functional cannot be applied to the multi-component nonuniform fluid systems with spatially varying composition, such as solid-fluid interfaces. As a test of the accuracy of our new functional, we apply it to the calculation of the freezing phase diagram of a binary hard-sphere fluid, and compare the results to simulation and the Denton-Ashcroft extension.Comment: 4 pages, 4 figures, to appear in Phys. Rev. E as Brief Repor

    Effects of antenatal betamethasone on preterm human and mouse ductus arteriosus: comparison with baboon data.

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    BackgroundAlthough studies involving preterm infants ≤34 weeks gestation report a decreased incidence of patent ductus arteriosus after antenatal betamethasone, studies involving younger gestation infants report conflicting results.MethodsWe used preterm baboons, mice, and humans (≤276/7 weeks gestation) to examine betamethasone's effects on ductus gene expression and constriction both in vitro and in vivo.ResultsIn mice, betamethasone increased the sensitivity of the premature ductus to the contractile effects of oxygen without altering the effects of other contractile or vasodilatory stimuli. Betamethasone's effects on oxygen sensitivity could be eliminated by inhibiting endogenous prostaglandin/nitric oxide signaling. In mice and baboons, betamethasone increased the expression of several developmentally regulated genes that mediate oxygen-induced constriction (K+ channels) and inhibit vasodilator signaling (phosphodiesterases). In human infants, betamethasone increased the rate of ductus constriction at all gestational ages. However, in infants born ≤256/7 weeks gestation, betamethasone's contractile effects were only apparent when prostaglandin signaling was inhibited, whereas at 26-27 weeks gestation, betamethasone's contractile effects were apparent even in the absence of prostaglandin inhibitors.ConclusionsWe speculate that betamethasone's contractile effects may be mediated through genes that are developmentally regulated. This could explain why betamethasone's effects vary according to the infant's developmental age at birth

    Exploration and exploitation in the presence of network externalities

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    This paper examines the conditions under which exploration of a new, incompatible technologyis conducive to firm growth in the presence of network externalities. In particular, this studyis motivated bythe divergent evolutions of the PC and the workstation markets in response to a new technology: reduced instruction set computing (RISC). In the PC market, Intel has developed new microprocessors bymaintaining compatibilitywith the established architecture, whereas it was radicallyr eplaced byRISC in the workstation market. History indicates that unlike the PC market, the workstation market consisted of a large number of power users, who are less sensitive to compatibilitythan ordinaryusers. Our numerical analysis indicates that the exploration of a new, incompatible technologyis more likelyto increase the chance of firm growth when there are a substantial number of power users or when a new technologyis introduced before an established technologytakes off. (; ; ;

    Persistence of maternal antibodies to influenza A virus among captive mallards (\u3ci\u3eAnas platyrhynchos\u3c/i\u3e)

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    Wild waterfowl are maintenance hosts of most influenza A virus (IAV) subtypes and are often the subjects of IAV surveillance and transmission models. While maternal antibodies have been detected in yolks and in nestlings for a variety of wild bird species and pathogens, the persistence of maternal antibodies to IAVs in mallard ducklings (Anas platyrhynchos) has not been previously investigated. Nonetheless, this information is important for a full understanding of IAV transmission dynamics because ducklings protected by maternal antibodies may not be susceptible to infection. In this study, we examined the transfer of IAV-specific maternal antibodies to ducklings. Blood samples were collected approximately every five days from ducklings hatched from hens previously infected with an H6 strain of IAV. Serum samples were tested for antibodies to IAV by an enzyme-linked immunosorbent assay. The median persistence of maternal antibodies in ducklings was 12.5 days (range: 4-33 days) post-hatch. The majority of ducklings (71%) had detectable maternal antibodies from 4 to 17 days post-hatch, while a small subset of individuals (29%) had detectable maternal antibodies for up to 21-33 days post-hatch. Antibody concentrations in hens near the time of egg laying were correlated with maternal antibody concentrations in the initial blood sample collected from ducklings (0-4 days post-hatch). Knowledge of the duration of maternal antibodies in ducklings will aid in the interpretation of IAV serological surveillance results and in the modeling of IAV transmission dynamics in waterfowl

    Prospectus, May 6, 1992

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    https://spark.parkland.edu/prospectus_1992/1013/thumbnail.jp
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