6,106 research outputs found
Instability of ion kinetic waves in a weakly ionized plasma
The fundamental higher-order Landau plasma modes are known to be generally
heavily damped. We show that these modes for the ion component in a weakly
ionized plasma can be substantially modified by ion-neutral collisions and a dc
electric field driving ion flow so that some of them can become unstable. This
instability is expected to naturally occur in presheaths of gas discharges at
sufficiently small pressures and thus affect sheaths and discharge structures.Comment: Published in Phys. Rev. E, see
http://link.aps.org/doi/10.1103/PhysRevE.85.02641
Collaborative semantic web browsing with Magpie
Web browsing is often a collaborative activity. Users involved in a joint information gathering exercise will wish to share knowledge about the web pages visited and the contents found. Magpie is a suite of tools supporting the interpretation of web pages and semantically enriched web browsing. By automatically associating an ontology-based semantic layer to web resources, Magpie allows relevant services to be invoked as well as remotely triggered within a standard web browser. In this paper we describe how Magpie trigger services can provide semantic support to collaborative browsing activities
The ant abdomen: The skeletomuscular and soft tissue anatomy of Amblyopone australis workers (Hymenoptera: Formicidae)
Recent studies of insect anatomy evince a trend towards a comprehensive and integrative investigation of individual traits and their evolutionary relationships. The abdomen of ants, however, remains critically understudied. To address this shortcoming, we describe the abdominal anatomy of Amblyopone australis Erichson, using a multimodal approach combining manual dissection, histology, and microcomputed tomography. We focus on skeletomusculature, but additionally describe the metapleural and metasomal exocrine glands, and the morphology of the circulatory, digestive, reproductive, and nervous systems. We describe the muscles of the dorsal vessel and the ducts of the venom and Dufour\u27s gland, and characterize the visceral anal musculature. Through comparison with other major ant lineages, apoid wasps, and other hymenopteran outgroups, we provide a first approximation of the complete abdominal skeletomuscular groundplan in Formicidae, with a nomenclatural schema generally applicable to the hexapod abdomen. All skeletal muscles were identifiable with their homologs, while we observe potential apomorphies in the pregenital skeleton and the sting musculature. Specifically, we propose the eighth coxocoxal muscle as an ant synapomorphy; we consider possible transformation series contributing to the distribution of states of the sternal apodemes in ants, Hymenoptera, and Hexapoda; and we address the possibly synapomorphic loss of the seventh sternalâeighth gonapophyseal muscles in the vespiform Aculeata. We homologize the ovipositor muscles across Hymenoptera, and summarize demonstrated and hypothetical muscle functions across the abdomen. We also give a new interpretation of the proximal processes of gonapophyses VIII and the ventromedial processes of gonocoxites IX, and make nomenclatural suggestions in the context of evolutionary anatomy and ontology. Finally, we discuss the utility of techniques applied and emphasize the value of primary anatomical research
Validation of Nike Fuel Band Step Counter in Children with Visual Impairments
Please view abstract in the attached PDF file
Motivational Effects of Physical Activity Monitoring Bands and Talking Pedometers on Children with Visual Impairments
Please view abstract in the attached PDF file
Harnack inequality and regularity for degenerate quasilinear elliptic equations
We prove Harnack inequality and local regularity results for weak solutions
of a quasilinear degenerate equation in divergence form under natural growth
conditions. The degeneracy is given by a suitable power of a strong
weight. Regularity results are achieved under minimal assumptions on the
coefficients and, as an application, we prove local estimates
for solutions of a degenerate equation in non divergence form
Application of a single-objective, hybrid genetic algorithm approach to pharmacokinetic model building.
A limitation in traditional stepwise population pharmacokinetic model building is the difficulty in handling interactions between model components. To address this issue, a method was previously introduced which couples NONMEM parameter estimation and model fitness evaluation to a single-objective, hybrid genetic algorithm for global optimization of the model structure. In this study, the generalizability of this approach for pharmacokinetic model building is evaluated by comparing (1) correct and spurious covariate relationships in a simulated dataset resulting from automated stepwise covariate modeling, Lasso methods, and single-objective hybrid genetic algorithm approaches to covariate identification and (2) information criteria values, model structures, convergence, and model parameter values resulting from manual stepwise versus single-objective, hybrid genetic algorithm approaches to model building for seven compounds. Both manual stepwise and single-objective, hybrid genetic algorithm approaches to model building were applied, blinded to the results of the other approach, for selection of the compartment structure as well as inclusion and model form of inter-individual and inter-occasion variability, residual error, and covariates from a common set of model options. For the simulated dataset, stepwise covariate modeling identified three of four true covariates and two spurious covariates; Lasso identified two of four true and 0 spurious covariates; and the single-objective, hybrid genetic algorithm identified three of four true covariates and one spurious covariate. For the clinical datasets, the Akaike information criterion was a median of 22.3 points lower (range of 470.5 point decrease to 0.1 point decrease) for the best single-objective hybrid genetic-algorithm candidate model versus the final manual stepwise model: the Akaike information criterion was lower by greater than 10 points for four compounds and differed by less than 10 points for three compounds. The root mean squared error and absolute mean prediction error of the best single-objective hybrid genetic algorithm candidates were a median of 0.2 points higher (range of 38.9 point decrease to 27.3 point increase) and 0.02 points lower (range of 0.98 point decrease to 0.74 point increase), respectively, than that of the final stepwise models. In addition, the best single-objective, hybrid genetic algorithm candidate models had successful convergence and covariance steps for each compound, used the same compartment structure as the manual stepwise approach for 6 of 7 (86 %) compounds, and identified 54 % (7 of 13) of covariates included by the manual stepwise approach and 16 covariate relationships not included by manual stepwise models. The model parameter values between the final manual stepwise and best single-objective, hybrid genetic algorithm models differed by a median of 26.7 % (qâ = 4.9 % and qâ = 57.1 %). Finally, the single-objective, hybrid genetic algorithm approach was able to identify models capable of estimating absorption rate parameters for four compounds that the manual stepwise approach did not identify. The single-objective, hybrid genetic algorithm represents a general pharmacokinetic model building methodology whose ability to rapidly search the feasible solution space leads to nearly equivalent or superior model fits to pharmacokinetic data
A remark on an overdetermined problem in Riemannian Geometry
Let be a Riemannian manifold with a distinguished point and
assume that the geodesic distance from is an isoparametric function.
Let be a bounded domain, with , and consider
the problem in with on ,
where is the -Laplacian of . We prove that if the normal
derivative of along the boundary of is a
function of satisfying suitable conditions, then must be a
geodesic ball. In particular, our result applies to open balls of
equipped with a rotationally symmetric metric of the form
, where is the standard metric of the sphere.Comment: 8 pages. This paper has been written for possible publication in a
special volume dedicated to the conference "Geometric Properties for
Parabolic and Elliptic PDE's. 4th Italian-Japanese Workshop", organized in
Palinuro in May 201
- âŠ