3,717 research outputs found
Square-planar vs. Trigonal bipyramidal geometry in Pt(II) complexes containing triazole-based glucose ligands as potential anticancer agents
This article describes the synthesis, characterization, and biological activity of novel square-planar cationic platinum(II) complexes containing glucoconjugated triazole ligands and a comparison with the results obtained from the corresponding five-coordinate complexes bearing the same triazole ligands. Stability in solution, reactivity with DNA and small molecules of the new compounds were evaluated by NMR, fluorescence, and UV–vis absorption spectroscopy, together with their cytotoxic action against pairs of immortalized and tumorigenic cell lines. The results show that the square-planar species exhibit greater stability than the corresponding five-coordinate ones. Furthermore, although the square-planar complexes are less cytotoxic than the latter ones, they exhibit a certain selectivity. These results simultaneously demonstrate that overall stability is a fundamental prerequisite for preserving the performance of the agents and that coordinative saturation constitutes a point in favor of their biological action
Compact relaxations for polynomial programming problems
Reduced RLT constraints are a special class of Reformulation- Linearization Technique (RLT) constraints. They apply to nonconvex (both continuous and mixed-integer) quadratic programming problems subject to systems of linear equality constraints. We present an extension to the general case of polynomial programming problems and discuss the derived convex relaxation. We then show how to perform rRLT constraint generation so as to reduce the number of inequality constraints in the relaxation, thereby making it more compact and faster to solve. We present some computational results validating our approach
Nuclear halo and the coherent nuclear interaction
The unusual structure of Li11, the first halo nucleus found, is analyzed by
the Preparata model of nuclear structure. By applying Coherent Nucleus Theory,
we obtain an interaction potential for the halo-neutrons that rightly
reproduces the fundamental state of the system.Comment: 9 pages Submitted to International Journal of Modern Physics E
(IJMPE
Ageing test of the ATLAS RPCs at X5-GIF
An ageing test of three ATLAS production RPC stations is in course at X5-GIF,
the CERN irradiation facility. The chamber efficiencies are monitored using
cosmic rays triggered by a scintillator hodoscope. Higher statistics
measurements are made when the X5 muon beam is available. We report here the
measurements of the efficiency versus operating voltage at different source
intensities, up to a maximum counting rate of about 700Hz/cm^2. We describe the
performance of the chambers during the test up to an overall ageing of 4 ATLAS
equivalent years corresponding to an integrated charge of 0.12C/cm^2, including
a safety factor of 5.Comment: 4 pages. Presented at the VII Workshop on Resistive Plate Chambers
and Related Detectors; Clermont-Ferrand October 20th-22nd, 200
Channel estimation method with improved performance for the UMTS-TDD mode
Channel estimation is an essential building block for UTRA-TDD high performance receivers. Once the performance of the channel estimator algorithm proposed by 3GPP is highly dependent on the time spreading between consecutive multi-path components, a Successive Multi-path channel Estimation Technique (SMET) that improves the time resolution is proposed in this paper. A SMET based maximum likelihood approach for vectorial channel estimation, to include the estimation of the direction-of-arrival, is also proposed. This algorithm solves efficiently the complex problem of DOA estimation of multiple users in a multi path propagation environment even when the number of required DOA's exceeds the number of antenna array elements. Another property of the proposed algorithm is its ability to resolve signals from different users arriving from the same direction. This is due to processing in both time and space dimensions. The performance of these algorithms is assessed by resorting to simulations in multi-path environments using the UMTS-TDD specifications, and also by comparing the rms estimation errors against the Crámer-Rao Bound. The effect of imperfect channel estimation on the performance of RAKE and Hard-Decision Parallel Interference Canceller receivers is also analysed. The results show that a good performance can be achieved with SMET, from low to high values of Eb/n0
Wax: A benign hydrogen-storage material that rapidly releases H2-rich gases through microwave-assisted catalytic decomposition
Hydrogen is often described as the fuel of the future, especially for application in hydrogen powered fuel-cell vehicles (HFCV’s). However, its widespread implementation in this role has been thwarted by the lack of a lightweight, safe, on-board hydrogen storage material. Here we show that benign, readily-available hydrocarbon wax is capable of rapidly releasing large amounts of hydrogen through microwave-assisted catalytic decomposition. This discovery offers a new material and system for safe and efficient hydrogen storage and could facilitate its application in a HFCV. Importantly, hydrogen storage materials made of wax can be manufactured through completely sustainable processes utilizing biomass or other renewable feedstocks
Entanglement in Many-Body Systems
The recent interest in aspects common to quantum information and condensed
matter has prompted a prosperous activity at the border of these disciplines
that were far distant until few years ago. Numerous interesting questions have
been addressed so far. Here we review an important part of this field, the
properties of the entanglement in many-body systems. We discuss the zero and
finite temperature properties of entanglement in interacting spin, fermionic
and bosonic model systems. Both bipartite and multipartite entanglement will be
considered. At equilibrium we emphasize on how entanglement is connected to the
phase diagram of the underlying model. The behavior of entanglement can be
related, via certain witnesses, to thermodynamic quantities thus offering
interesting possibilities for an experimental test. Out of equilibrium we
discuss how to generate and manipulate entangled states by means of many-body
Hamiltonians.Comment: 61 pages, 29 figure
Nonlinear Integer Programming
Research efforts of the past fifty years have led to a development of linear
integer programming as a mature discipline of mathematical optimization. Such a
level of maturity has not been reached when one considers nonlinear systems
subject to integrality requirements for the variables. This chapter is
dedicated to this topic.
The primary goal is a study of a simple version of general nonlinear integer
problems, where all constraints are still linear. Our focus is on the
computational complexity of the problem, which varies significantly with the
type of nonlinear objective function in combination with the underlying
combinatorial structure. Numerous boundary cases of complexity emerge, which
sometimes surprisingly lead even to polynomial time algorithms.
We also cover recent successful approaches for more general classes of
problems. Though no positive theoretical efficiency results are available, nor
are they likely to ever be available, these seem to be the currently most
successful and interesting approaches for solving practical problems.
It is our belief that the study of algorithms motivated by theoretical
considerations and those motivated by our desire to solve practical instances
should and do inform one another. So it is with this viewpoint that we present
the subject, and it is in this direction that we hope to spark further
research.Comment: 57 pages. To appear in: M. J\"unger, T. Liebling, D. Naddef, G.
Nemhauser, W. Pulleyblank, G. Reinelt, G. Rinaldi, and L. Wolsey (eds.), 50
Years of Integer Programming 1958--2008: The Early Years and State-of-the-Art
Surveys, Springer-Verlag, 2009, ISBN 354068274
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