Electric Momentum: Dynamics of Transportation Electrification and Stories from the Road

The climate is undeniably changing. The Intergovernmental Panel on Climate Change (IPCC) published yet another report this year outlining how extreme weather, brought on by our use of Earth\u27s resources, causes loss of nature and human life around the world. The summer of 2023 broke records for high ocean temperatures and melting polar ice, and abnormally potent floods and fires touched all corners of the Earth. Industrial production of goods, and the personal choices that purchase them, are responsible for massive amounts of greenhouse gases (GHG), including carbon dioxide and methane. GHG emissions thicken the Earth\u27s atmosphere and continue the destabilization of the climate. It\u27s an all-encompassing phenomenon that asks us to reevaluate our relationship with the world: how we extract, consume, and dispose of renewable and non-renewable resources. The United States ranks second in the world for GHG emissions. Transportation is the most significant GHG-emitting sector of the US economy. Passenger vehicles contribute more than half of all transportation emissions. Electric vehicles may be one useful solution to reducing GHG emissions in this country. Rural schools and households have a unique opportunity to benefit from transportation electrification, if government subsidies and public charging infrastructure is in place. This portfolio of journalistic work explores the dynamics of emerging EV technology and to what extent the efficiency and reliability of these vehicles may reduce our climate impacts

Meat for Missoula: Educating Our Youth on Sustainable Meat Production Practices

In autumn 2016, a controversy arose when a student group, Advocates for Animals, took up a campaign against three meat pigs at the PEAS Farm due to strong views about animal consumption. Pigs serve as a central piece of food source education to hundreds of Missoula children who visit the farm every year. Unfortunately, the controversy overshadowed the educational purpose of exposing children to sustainable meat production practices. Moreover, access to the PEAS Farm and good food education is not available to all local children. I wondered whether education was accessible elsewhere. Unfortunately, child-appropriate, culturally relevant food literature is scarce. In my research, I read and critiqued dozens of children’s books on food and farming. However, much of the literature is outdated, inaccurate, or dull. In response, I have written and illustrated a children’s book that provides accurate and relevant information with engaging illustrations. This book could reach an audience that cannot visit the PEAS Farm or access other sustainable food education resources. Offering this kind of information to children allows for important discussion of where food comes from and what kind of food we want in our community

The rare case of positive FDG-positron emission tomography for giant cavernous hemangioma of the liver

Hemangioma is the most common benign liver tumor and the second most common liver tumor after metastases. Large hemangiomas are often heterogeneous. When they exceed 4 cm in diameter, they are termed giant hemangiomas. These giant hemangiomas often present heterogeneous patterns. These heterogeneous appearances are shown because of intratumoral changes due to several degenerative phenomena. PET/CT is reported to be useful for the differentiation of benign from malignant liver lesions. We report the case of a large hepatic hemangioma characterized by high FDG uptake

Analysis of seismically-isolated two-block systems using a multi–rocking-body dynamic model

A novel multibody rocking model is developed to investigate the dynamic response of two stacked rigid blocks placed on a linear base isolation device. The model is used to investigate the dynamic response of a realistic statue-pedestal system subject to pulse-like ground motions. The analysis shows that, in general, base isolation increases the safety level of the rocking system. However, for large period pulses or small size blocks, the isolator can amplify the ground motion, resulting in a lower minimum overturning acceleration than for the nonisolated system. Further, the amplification or shock spectrum of a linear mass-dashpot-spring oscillator, was found to be the reciprocal of the minimum nondimensional overturning acceleration of the investigated rocking system. Novel rocking spectra are obtained by normalizing the frequency of the pulse by the frequency of the isolator. The analysis also demonstrates how the dynamic response of the two stacked blocks is equivalent to that of a single-block configuration coincident with the whole system assumed monolithic or the upper block alone, whichever is more slender

Displacement-based design procedures for rigid block isolation

When subjected to earthquakes, many objects or structural elements behave like rocking rigid blocks. Computer servers, medical shelves, art objects, statues, and electrical transformers are frequently included in this category. Protection of these objects is an important task, considering that their value could be inestimable or their operation crucial during earthquakes; base isolation technology has been proven to be a viable option for this purpose. Initially, the dynamic model of a rocking rigid block placed on a base isolation device is reviewed. Then, two equivalent-static displacement-based procedures for designing the isolators for these types of objects are proposed, and the main steps are illustrated. The first procedure aims to determine isolator characteristics to prevent the initiation of rocking motion during the code-level earthquake event. The second procedure is aimed at designing isolators that allow a specified maximum rotation of the block during seismic events. The proposed procedures are validated by means of time-history analyses for a suite of spectrum-compatible accelerograms. The first displacement-based procedure appears particularly suitable for objects of small to medium size. The validation of the second procedure demonstrates that the equal displacement rule can be applied for this kind of systems, despite their softening. The results also indicate that the approach is particularly effective for medium to large structures/objects, if small oscillations are acceptable. The controlled rocking procedure offers a significant advantage by allowing for a reduction in the maximum displacement and period of the isolator, compared to situations where rocking motion must be prevented entirely

CPC-135 The Effect of Gender on the Use of Medicines in Multiple Sclerosis Patients

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Pseudozyma aphidis bloodstream infection in a patient with aggressive lymphoma and a history of intravenous drug use: Case report and review of the literature

Pseudozyma aphidis is an environmental fungus which causes opportunistic infections in immunocompromised patients. Here we report the case of a 54-year-old, intravenous drug user woman, newly diagnosed to have an aggressive lymphoma, who developed a bloodstream infection caused by P. aphidis treated successfully with amphotericin-B therapy. The precise identification was assessed by sequencing. We propose to consider intravenous drug use as a risk factor for invasive infections due to this environmental yeast

N-Acetylcysteine causes analgesia in a mouse model of painful diabetic neuropathy

N-Acetylcysteine, one of the most prescribed antioxidant drugs, enhances pain threshold in rodents and humans by activating mGlu2 metabotropic glutamate receptors. Here, we assessed the analgesic activity of N-acetylcysteine in the streptozotocin model of painful diabetic neuropathy and examined the effect of N-acetylcysteine on proteins that are involved in mechanisms of nociceptive sensitization. Mice with blood glucose levels ≥250 mg/dl in response to a single intraperitoneal (i.p.) injection of streptozotocin (200 mg/kg) were used for the assessment of mechanical pain thresholds. Systemic treatment with N-acetylcysteine (100 mg/kg, i.p., either single injection or daily injections for seven days) caused analgesia in diabetic mice. N-acetylcysteine-induced analgesia was abrogated by the Sxc- inhibitors, sulfasalazine (8 mg/kg, i.p.), erastin (30 mg/kg, i.p.), and sorafenib (10 mg/kg, i.p.), or by the mGlu2/3 receptor antagonist, LY341495 (1 mg/kg, i.p.). Repeated administrations of N-acetylcysteine in diabetic mice reduced ERK1/2 phosphorylation in the dorsal region of the lumbar spinal cord. The analgesic activity of N-acetylcysteine was occluded by the MEK inhibitor, PD0325901 (25 mg/kg, i.p.), the TRPV1 channel blocker, capsazepine (40 mg/kg, i.p.), or by a cocktail of NMDA and mGlu5 metabotropic glutamate receptor antagonists (memantine, 25 mg/kg, plus MTEP, 5 mg/kg, both i.p.). These findings offer the first demonstration that N-acetylcysteine relieves pain associated with diabetic neuropathy and holds promise for the use of N-acetylcysteine as an add-on drug in diabetic patients