A multiregion assessment of observed changes in the areal extent of temperature and precipitation extremes

This study examines trends in the area affected by temperature and precipitation extremes across five large-scale regions using the climate extremes index (CEI) framework. Analyzing changes in temperature and precipitation extremes in terms of areal fraction provides information from a different perspective and can be useful for climate monitoring. Trends in five temperature and precipitation components are analyzed, calculated using a new method based on standard extreme indices. These indices, derived from daily meteorological station data, are obtained from two global land-based gridded extreme indices datasets. The four continental-scale regions of Europe, North America, Asia, and Australia are analyzed over the period from 1951 to 2010, where sufficient data coverage is available. These components are also computed for the entire Northern Hemisphere, providing the first CEI results at the hemispheric scale. Results show statistically significant increases in the percentage area experiencing much-above-average warm days and nights and much-below-average cool days and nights for all regions, with the exception of North America for maximum temperature extremes. Increases in the area affected by precipitation extremes are also found for the Northern Hemisphere regions, particularly Europe and North America

Comparison of Forced ENSO-Like Hydrological Expressions in Simulations of the Preindustrial and Mid-Holocene

Using the water isotope- and vapor source distribution (VSD) tracer-enabled Goddard Institute for Space Studies ModelE-R, we examine changing El Nino-Southern Oscillation (ENSO)-like expressions in the hydrological cycle in a suite of model experiments. We apply strong surface temperature anomalies associated with composite observed El Nino and La Nina events as surface boundary conditions to preindustrial and mid-Holocene model experiments in order to investigate ENSO-like expressions in the hydrological cycle under varying boundary conditions. We find distinct simulated hydrological anomalies associated with El Nino-like ("ENSOWARM") and La Nina-like ("ENSOCOOL") conditions, and the region-specific VSD tracers show hydrological differences across the Pacific basin between El Nino-like and La Nina-like events. The application of ENSOCOOL forcings does not produce climatological anomalies that represent the equal but opposite impacts of the ENSOWARM experiment, as the isotopic anomalies associated with ENSOWARM conditions are generally stronger than with ENSOCOOL and the spatial patterns of change distinct. Also, when the same ENSO-like surface temperature anomalies are imposed on the mid-Holocene, the hydrological response is muted, relative to the preindustrial. Mid-Holocene changes in moisture sources to the analyzed regions across the Pacific reveal potentially complex relationships between ENSO-like conditions and boundary conditions. Given the complex impacts of ENSO-like conditions on various aspects of the hydrological cycle, we suggest that proxy record insights into paleo-ENSO variability are most likely to be robust when synthesized from a network of many spatially diverse archives, which can account for the potential nonstationarity of ENSO teleconnections under different boundary conditions

Modeling Insights into Deuterium Excess as an Indicator of Water Vapor Source Conditions

Deuterium excess (d) is interpreted in conventional paleoclimate reconstructions as a tracer of oceanic source region conditions, such as temperature, where precipitation originates. Previous studies have adopted co-isotopic approaches to estimate past changes in both site and oceanic source temperatures for ice core sites using empirical relationships derived from conceptual distillation models, particularly Mixed Cloud Isotopic Models (MCIMs). However, the relationship between d and oceanic surface conditions remains unclear in past contexts. We investigate this climate-isotope relationship for sites in Greenland and Antarctica using multiple simulations of the water isotope-enabled Goddard Institute for Space Studies (GISS) ModelE-R general circulation model and apply a novel suite of model vapor source distribution (VSD) tracers to assess d as a proxy for source temperature variability under a range of climatic conditions. Simulated average source temperatures determined by the VSDs are compared to synthetic source temperature estimates calculated using MCIM equations linking d to source region conditions. We show that although deuterium excess is generally a faithful tracer of source temperatures as estimated by the MCIM approach, large discrepancies in the isotope-climate relationship occur around Greenland during the Last Glacial Maximum simulation, when precipitation seasonality and moisture source regions were notably different from present. This identified sensitivity in d as a source temperature proxy suggests that quantitative climate reconstructions from deuterium excess should be treated with caution for some sites when boundary conditions are significantly different from the present day. Also, the exclusion of the influence of humidity and other evaporative source changes in MCIM regressions may be a limitation of quantifying source temperature fluctuations from deuterium excess in some instances

A multiregion model evaluation and attribution study of historical changes in the area affected by temperature and precipitation extremes

The skill of eight climate models in simulating the variability and trends in the observed areal extent of daily temperature and precipitation extremes is evaluated across five large-scale regions, using the climate extremes index (CEI) framework. Focusing on Europe, North America, Asia, Australia, and the Northern Hemisphere, results show that overall the models are generally able to simulate the decadal variability and trends of the observed temperature and precipitation components over the period 1951–2005. Climate models are able to reproduce observed increasing trends in the area experiencing warm maximum and minimum temperature extremes, as well as, to a lesser extent, increasing trends in the areas experiencing an extreme contribution of heavy precipitation to total annual precipitation for the Northern Hemisphere regions. Using simulations performed under different radiative forcing scenarios, the causes of simulated and observed trends are investigated. A clear anthropogenic signal is found in the trends in the maximum and minimum temperature components for all regions. In North America, a strong anthropogenically forced trend in the maximum temperature component is simulated despite no significant trend in the gridded observations, although a trend is detected in a reanalysis product. A distinct anthropogenic influence is also found for trends in the area affected by a much-above-average contribution of heavy precipitation to annual precipitation totals for Europe in a majority of models and to varying degrees in other Northern Hemisphere regions. However, observed trends in the area experiencing extreme total annual precipitation and extreme number of wet and dry days are not reproduced by climate models under any forcing scenario

Understanding the role of sea surface temperature-forcing for variability in global temperature and precipitation extremes

The oceans are a well-known source of natural variability in the climate system, although their ability to account for inter-annual variations of temperature and precipitation extremes over land remains unclear. In this study, the role of sea-surface temperature (SST)-forcing is investigated for variability and trends in a range of commonly used temperature and precipitation extreme indices over the period 1959 to 2013. Using atmospheric simulations forced by observed SST and sea-ice concentrations (SIC) from three models participating in the Climate of the Twentieth Century Plus (C20C+) Project, results show that oceanic boundary conditions drive a substantial fraction of inter-annual variability in global average temperature extreme indices, as well as, to a lower extent, for precipitation extremes. The observed trends in temperature extremes are generally well captured by the SST-forced simulations although some regional features such as the lack of warming in daytime warm temperature extremes over South America are not reproduced in the model simulations. Furthermore, the models simulate too strong increases in warm day frequency compared to observations over North America. For extreme precipitation trends, the accuracy of the simulated trend pattern is regionally variable, and a thorough assessment is difficult due to the lack of locally significant trends in the observations. This study shows that prescribing SST and SIC holds potential predictability for extremes in some (mainly tropical) regions at the inter-annual time-scale

Annexin-enriched osteoblast-derived vesicles act as an extracellular site of mineral nucleation within developing stem cell cultures

The application of extracellular vesicles (EVs) as natural delivery vehicles capable of enhancing tissue regeneration could represent an exciting new phase in medicine. We sought to define the capacity of EVs derived from mineralising osteoblasts (MO-EVs) to induce mineralisation in mesenchymal stem cell (MSC) cultures and delineate the underlying biochemical mechanisms involved. Strikingly, we show that the addition of MO-EVs to MSC cultures significantly (P < 0.05) enhanced the expression of alkaline phosphatase, as well as the rate and volume of mineralisation beyond the current gold-standard, BMP-2. Intriguingly, these effects were only observed in the presence of an exogenous phosphate source. EVs derived from non-mineralising osteoblasts (NMO-EVs) were not found to enhance mineralisation beyond the control. Comparative label-free LC-MS/MS profiling of EVs indicated that enhanced mineralisation could be attributed to the delivery of bridging collagens, primarily associated with osteoblast communication, and other non-collagenous proteins to the developing extracellular matrix. In particular, EV-associated annexin calcium channelling proteins, which form a nucleational core with the phospholipid-rich membrane and support the formation of a pre-apatitic mineral phase, which was identified using infrared spectroscopy. These findings support the role of EVs as early sites of mineral nucleation and demonstrate their value for promoting hard tissue regeneration

Hepatitis E in England and Wales

In 2005, 329 cases of hepatitis E virus infection were confirmed in England and Wales; 33 were confirmed indigenous infections, and a further 67 were estimated to be indigenous infections. Hepatitis E should be considered in the investigation of patients with hepatitis even if they have no history of travel

Deep ocean drivers better explain habitat preferences of sperm whales Physeter macrocephalus than beaked whales in the Bay of Biscay

Species Distribution Models are commonly used with surface dynamic environmental variables as proxies for prey distribution to characterise marine top predator habitats. For oceanic species that spend lot of time at depth, surface variables might not be relevant to predict deep-dwelling prey distributions. We hypothesised that descriptors of deep-water layers would better predict the deep-diving cetacean distributions than surface variables. We combined static variables and dynamic variables integrated over different depth classes of the water column into Generalised Additive Models to predict the distribution of sperm whales Physeter macrocephalus and beaked whales Ziphiidae in the Bay of Biscay, eastern North Atlantic. We identified which variables best predicted their distribution. Although the highest densities of both taxa were predicted near the continental slope and canyons, the most important variables for beaked whales appeared to be static variables and surface to subsurface dynamic variables, while for sperm whales only surface and deep-water variables were selected. This could suggest differences in foraging strategies and in the prey targeted between the two taxa. Increasing the use of variables describing the deep-water layers would provide a better understanding of the oceanic species distribution and better assist in the planning of human activities in these habitats.Versión del edito

The timing of anthropogenic emergence in simulated climate extremes

Determining the time of emergence of climates altered from their natural state by anthropogenic influences can help inform the development of adaptation and mitigation strategies to climate change. Previous studies have examined the time of emergence of climate averages. However, at the global scale, the emergence of changes in extreme events, which have the greatest societal impacts, has not been investigated before. Based on state-of-the-art climate models, we show that temperature extremes generally emerge slightly later from their quasi-natural climate state than seasonal means, due to greater variability in extremes. Nevertheless, according to model evidence, both hot and cold extremes have already emerged across many areas. Remarkably, even precipitation extremes that have very large variability are projected to emerge in the coming decades in Northern Hemisphere winters associated with a wettening trend. Based on our findings we expect local temperature and precipitation extremes to already differ significantly from their previous quasi-natural state at many locations or to do so in the near future. Our findings have implications for climate impacts and detection and attribution studies assessing observed changes in regional climate extremes by showing whether they will likely find a fingerprint of anthropogenic climate change