Od fana do stalkera. Spektrum postaw fanowskich w koreańskim przemyśle kulturowym

The article characterizes three fannish attitudes among South Korean audience of popular culture – the True Fan, the Ani-Fan and the Saseang (Obsessive Fan) by discussing fan activities and practices. The author puts particular emphasis on the Korean music industry, and its top-down way of structuring and manipulating the fan-object of affection as well as intra-fandom relationships through enforcing models of behavior and interaction with idols among fans. The category of parasocial relationship is key to this analysis as central to Korean pop culture industry; other concepts discussed include bottom-up and top-down practices and Deleuze’s rhizomatic concept of culture, especially fitting for a discussion concerning the fan niche system found in South Korea as well as the interactions between the fandom and the pop culture industry.Artykuł prezentuje aktywności i praktyki fanowskie wśród południowokoreańskich odbiorców kultury popularnej celem ogólnej charakterystyki dostępnych postaw, które mieszczą się w modelowych ujęciach Prawdziwego Fana, Anty-fana i Saseang – Fan Obsesyjnego. Zwraca się tu uwagę na szczególną rolę koreańskiego przemysłu muzycznego, który odgórnie strukturyzuje i manipuluje relacją fan – obiekt afektu oraz relacjami wewnątrzfandomowy, narzucając sposoby interakcji z idolami i modele zachowań wśród fanów. Kluczowe w analizie są kategorie relacji paraspołecznej jako centralnej dla struktury koreańskiego przemysłu kulturowego, praktyk oddolnych i odgórnych oraz koncepcji kultury kłączowatej Delezue, która szczególnie przystaje do opisu systemu fanowskich „nisz ekologicznych” w Korei Południowej i interakcji między fandomem a przemysłem kulturowym

Jurisdiction in Matters of Succession on the Basis of Regulation (EU) NO 650/2012

Purpose – The aim of this presentation is to show the importance of EU Regulation in matters of succession and its consequences on legal position of EU citizens. Owing to above the speech will be present the different kind of jurisdiction, depending of the connector. On the top of that, the presentation will concern the issue of international civil procedure introduced by Polish code and its relation to EU Regulation

Jurisdiction in the Succession Matters under the Regulation (EU) NO 650/2012 of the European Parliament and of the Council of 4 july 2012 in the Face of Polish International Civil Procedure

The aim of the article is to present the impact of EU Regulation no. 650/2012 on determination of jurisdiction in succession matters. The paper presents the distinction between Polish and European system of admitting jurisdiction and its consequence

Monocyte-Derived Dendritic Cells as Model to Evaluate Species Tropism of Mosquito-Borne Flaviviruses

Several mosquito-borne Flaviviruses such as Japanese encephalitis virus (JEV), West Nile virus (WNV), Dengue Virus (DENV), and Zika virus (ZIKV) can cause severe clinical disease. Being zoonotic, Flaviviruses infect a wide variety of terrestrial vertebrates, which dependent of the virus-host interactions, can enhance ongoing epidemics and maintain the virus in the environment for prolonged periods. Targeted species can vary from amphibians, birds to various mammals, dependent on the virus. For many mosquito-borne flaviviruses the spectrum of targeted species is incompletely understood, in particular with respect to their contribution to the maintenance of virus in certain geographical regions. Furthermore, little is known about virus and host factors contributing to species tropism. The present study utilized human and porcine monocyte-derived dendritic cells (MoDC) as a cell culture model to better understand Flavivirus species tropism and innate immune responses. MoDC were selected based on their presence in the skin and their role as an early target cell for several Flaviviruses and their role as immune sentinels. While differences in viral infectivity and replication were minor when comparing porcine with human MoDC for some of the tested Flaviviruses, a particularly strong replication in human MoDC was found with USUV, while JEV appeared to have a stronger tropism for porcine MoDC. With respect to innate immune responses we found high induction of TNF and IFN-β in both human and porcine MoDC after infection with JEV, WNV, and USUV, but not with DENV, ZIKV, and Wesselsbron virus. Spondweni virus induced these cytokine responses only in porcine MoDC. Overall, innate immune responses correlated with early infectivity and cytokine production. In conclusion, we demonstrate Flavivirus-dependent differences in the interaction with MoDC. These may play a role in pathogenesis but appear to only partially reflect the expected species tropism

The analysis of incidence of risk factors of neoplastic diseases among patients with a diagnosed neoplastic disease

Introduction: Risk of neoplastic diseases in the whole world’s population has been increasing regularly. Thanks to the GLOBACAN data base operating under the auspices of the International Union Against Cancer it has been reported that up to 2002 10,900,000 of new cases of cancer were diagnosed and 6,700 deaths were reported. According to the World Health Organization, in 2020 we may expect about 10 million deaths, including 7-8 millions in the developing countries, while this number in the developed countries will not change and will be 2-3 million. The world’s most frequently occurring tumour is lung cancer. It accounts for 12.4% of all tumours diagnosed. According to the epidemiological research, the basic factors responsible for cancer development among people are those environmental factors that result from humans’ behaviour.Objective: The objective is to analyze the occurrence of risk factors of a neoplastic disease among patients with a diagnosed oncological disease.Material and methods: The research involved 500 patients of the oncology department. Women accounted for more than a half of all patients, namely 58%, while men 42%. In order to obtain the research material, a standardized questionnaire has been applied, including interview and physical examination, enabling assessment and analysis of occurrence of cancer risk factors.Results: The most frequently diagnosed tumour among women is breast cancer (20%), while among men the most frequently occurring is prostate cancer (10%). 20% of women and 10% of men lived near high-voltage line. 11% of women were active smokers while 6% passive smokers. When it comes to men, 18% were active smokers, while 5% passive smokers.Conclusions: The most frequent cancer among women is breast cancer, while among men prostate cancer. Smoking does not have a significant influence on cancer development in women, however, it has a significant influence on cancer development in men. Overweight and obesity have a significant influence on cancer development in women, while they have insignificant influence on cancer development in men

Living with cancer and multi-morbidity: the role of primary care

As more people live longer with cancer, the number of patients with cancer and multiple other chronic conditions (multimorbidity) has increased. The presence of multimorbidity impacts on all stages of cancer care, from prevention and early detection through to end of life care, but research into cancer and multimorbidity is in its infancy. This review explores the impact of multimorbidity on adults living with (and beyond) cancer, with particular attention paid to the role of primary care in supporting patients in this situation. Patterns of multimorbidity vary depending on cancer type and stage, as well as population characteristics and available data (e.g. number of conditions assessed). Cancer survivors are at increased risk of developing other chronic conditions, due to a combination of shared risk factors (e.g. smoking and obesity), effects of cancer treatments and psychosocial effects. Primary care has a central role to play in supporting multimorbid adults living with cancer, providing holistic care of physical and mental well being, while taking treatment burden and social circumstances into account. New models of person-centred and personalized cancer care include holistic needs assessments, care planning, treatment summaries and cancer care reviews, and depend on improved communication between oncologists and primary care colleagues

The potential of microelectrode arrays and microelectronics for biomedical research and diagnostics

Planar microelectrode arrays (MEAs) are devices that can be used in biomedical and basic in vitro research to provide extracellular electrophysiological information about biological systems at high spatial and temporal resolution. Complementary metal oxide semiconductor (CMOS) is a technology with which MEAs can be produced on a microscale featuring high spatial resolution and excellent signal-to-noise characteristics. CMOS MEAs are specialized for the analysis of complete electrogenic cellular networks at the cellular or subcellular level in dissociated cultures, organotypic cultures, and acute tissue slices; they can also function as biosensors to detect biochemical events. Models of disease or the response of cellular networks to pharmacological compounds can be studied in vitro, allowing one to investigate pathologies, such as cardiac arrhythmias, memory impairment due to Alzheimer's disease, or vision impairment caused by ganglion cell degeneration in the retin

Microstructure and mechanical properties of friction stir welded joints made from ultrafine grained aluminium 1050

In order to obtain ultrafine grained structure, commercially pure aluminium (Al 1050) plates were subjected up to 8 passes of Incremental Equal Channel Angular Pressing (IECAP) following route C. Plates in different stages of IECAP were joined using Friction Stir Welding (FSW). All welded samples were investigated to determine their mechanical properties and structure evolution in the joint zone. The joining process reduced mechanical strength of material in the nugget zone, which was explained by the grain growth resulting from temperature rise during FSW. Nevertheless, the obtained results are promising in comparison to other methods of joining aluminium

Bearing the Burden of Tick-Borne Encephalitis in Europe, 2012-2020: Rising Cases, Future Predictions and Climate Change

Background: Tick-borne encephalitis (TBE) is a central nervous system disease that is posing a growing public health challenge in Europe. Its disease burden, despite carrying a significant global impact, is still relatively unexplored. This study aims to outline a regression model of how the increasing cases will influence the burden of TBE in the upcoming years, using YLDs (years lived with disability) and DALYs (Disability-adjusted life years), and address climate change as a determinant. Methods: Information regarding the number of cases, YLDs and DALYs of TBE was collected from European countries using available surveillance data from 2012 to 2020. Number of TBE cases and burden projections were created until 2025, using a linear regression model. The total reported cases of TBE cases in this timeframe, age-group and gender distribution were inserted and modeled in ECDC BCoDE Toolkit, a software application that calculates the burden of communicable diseases, YLDs and DALYs of each year. A non-systematic bibliographic search was conducted exploring the impact of climate change on TBE. Results: Our findings showed a linear growth in number of TBE cases (74.3% increase), DALYs (71.3%), YLDs (71.75%) in European countries from 2012 to 2020. By 2025, these factors are likely to increase by 141% (95% CI: [108%,175%]), 134% (95% CI: [91%,177%]) and 134% (95% CI: [98%,172%]) compared to 2012, respectively (p<0.0001). Conclusions: The likelihood of morbidity and mortality increase of TBE, as well as climate-related changes in tick activity, highlight that prompt action is necessary by introducing preventive measures in European populations