Pseudospin, Spin, and Coulomb Dirac-Symmetries: Doublet Structure and Supersymmetric Patterns

Relativistic symmetries of the Dirac Hamiltonian with a mixture of spherically symmetric Lorentz scalar and vector potentials, are examined from the point of view of supersymmetric quantum mechanics. The cases considered include the Coulomb, pseudospin and spin limits relevant, respectively, to atoms, nuclei and hadrons.Comment: 8 pages, 1 figure, Proc. Int. Workshop on "Blueprints for the Nucleus: From First Principles to Collective Motion", May 17-23, 2004, Feza Gursey Institute, Istanbul, Turke

Energy Level Statistics of the U(5) and O(6) Symmetries in the Interacting Boson Model

We study the energy level statistics of the states in U(5) and O(6) dynamical symmetries of the interacting boson model and the high spin states with backbending in U(5) symmetry. In the calculations, the degeneracy resulting from the additional quantum number is eliminated manually. The calculated results indicate that the finite boson number $N$ effect is prominent. When $N$ has a value close to a realistic one, increasing the interaction strength of subgroup O(5) makes the statistics vary from Poisson-type to GOE-type and further recover to Poisson-type. However, in the case of $N \to \infty$, they all tend to be Poisson-type. The fluctuation property of the energy levels with backbending in high spin states in U(5) symmetry involves a signal of shape phase transition between spherical vibration and axial rotation.Comment: 38 pages, 13 figure

Quadrupole shape invariants in the interacting boson model

In terms of the Interacting Boson Model, shape invariants for the ground state, formed by quadrupole moments up to sixth order, are studied in the dynamical symmetry limits and, for the first time, over the whole structural range of the IBM-1. The results are related to the effective deformation parameters and their fluctuations in the geometrical model. New signatures that can distinguish vibrator and gamma-soft rotor structures, and one that is related to shape coexistence, are identified.Comment: 10 pages, ReVTeX, epsf, 2 Postscript figures include

Extended M1 sum rule for excited symmetric and mixed-symmetry states in nuclei

A generalized M1 sum rule for orbital magnetic dipole strength from excited symmetric states to mixed-symmetry states is considered within the proton-neutron interacting boson model of even-even nuclei. Analytic expressions for the dominant terms in the B(M1) transition rates from the first and second $2^+$ states are derived in the U(5) and SO(6) dynamic symmetry limits of the model, and the applicability of a sum rule approach is examined at and in-between these limits. Lastly, the sum rule is applied to the new data on mixed-symmetry states of 94Mo and a quadrupole d-boson ratio $nd(0^+_1)/nd(2^+_2) \approx 0.6$ is obtained in a largely parameter-independent wayComment: 19 pages, 3 figures, Revte

SU(3) realization of the rigid asymmetric rotor within the IBM

It is shown that the spectrum of the asymmetric rotor can be realized quantum mechanically in terms of a system of interacting bosons. This is achieved in the SU(3) limit of the interacting boson model by considering higher-order interactions between the bosons. The spectrum corresponds to that of a rigid asymmetric rotor in the limit of infinite boson number.Comment: 9 pages, 2 figures, LaTeX, epsfi

Universal Predictions for Statistical Nuclear Correlations

We explore the behavior of collective nuclear excitations under a multi-parameter deformation of the Hamiltonian. The Hamiltonian matrix elements have the form $P(|H_{ij}|)\propto 1/\sqrt{|H_{ij}|}\exp(-|H_{ij}|/V)$, with a parametric correlation of the type $\log \langle H(x)H(y)\rangle\propto -|x-y|$. The studies are done in both the regular and chaotic regimes of the Hamiltonian. Model independent predictions for a wide variety of correlation functions and distributions which depend on wavefunctions and energies are found from parametric random matrix theory and are compared to the nuclear excitations. We find that our universal predictions are observed in the nuclear states. Being a multi-parameter theory, we consider general paths in parameter space and find that universality can be effected by the topology of the parameter space. Specifically, Berry's phase can modify short distance correlations, breaking certain universal predictions.Comment: Latex file + 12 postscript figure

An efficient integral equation technique for the analysis of arbitrarily shaped capacitive waveguide circuits

In this contribution a new and efficient integral equation formulation is presented for the analysis of arbitrarily shaped capacitive waveguide devices. The technique benefits from the symmetry of the structure in order to reduce the dimensions of the problem from three to two dimensions. For the first time, this technique formulates the waveguide capacitive discontinuity problem as a 2-D scattering problem with oblique incidence, combined with an efficient calculation of the parallel plate Green's functions. The numerical method allows the efficient evaluation of the electromagnetic fields inside the analyzed structures. Results for different practical capacitive waveguide devices are successfully compared with commercial software tools for validation of the proposed theory. Finally, a novel low-pass filter implementation based on circular conducting posts has been proposed. The field contour lines in the critical gaps of the new structure are curved due to the use of rounded posts. This could result in improved power handling capabilities with respect to standard corrugated low-pass filters. Copyright 2011 by the American Geophysical Union.This work has been developed with financial support from SENECA project reference 08833/PI/08, and CICYT project reference TEC2007-67630-C03.Quesada Pereira, FD.; Vera Castejon, P.; Alvarez Melcon, A.; Gimeno Martinez, B.; Boria Esbert, VE. (2011). An efficient integral equation technique for the analysis of arbitrarily shaped capacitive waveguide circuits. Radio Science. 46:1-11. doi:10.1029/2010RS004458S1114

Heterologous Expression of Membrane Proteins: Choosing the Appropriate Host

International audienceBACKGROUND: Membrane proteins are the targets of 50% of drugs, although they only represent 1% of total cellular proteins. The first major bottleneck on the route to their functional and structural characterisation is their overexpression; and simply choosing the right system can involve many months of trial and error. This work is intended as a guide to where to start when faced with heterologous expression of a membrane protein. METHODOLOGY/PRINCIPAL FINDINGS: The expression of 20 membrane proteins, both peripheral and integral, in three prokaryotic (E. coli, L. lactis, R. sphaeroides) and three eukaryotic (A. thaliana, N. benthamiana, Sf9 insect cells) hosts was tested. The proteins tested were of various origins (bacteria, plants and mammals), functions (transporters, receptors, enzymes) and topologies (between 0 and 13 transmembrane segments). The Gateway system was used to clone all 20 genes into appropriate vectors for the hosts to be tested. Culture conditions were optimised for each host, and specific strategies were tested, such as the use of Mistic fusions in E. coli. 17 of the 20 proteins were produced at adequate yields for functional and, in some cases, structural studies. We have formulated general recommendations to assist with choosing an appropriate system based on our observations of protein behaviour in the different hosts. CONCLUSIONS/SIGNIFICANCE: Most of the methods presented here can be quite easily implemented in other laboratories. The results highlight certain factors that should be considered when selecting an expression host. The decision aide provided should help both newcomers and old-hands to select the best system for their favourite membrane protein